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2,057 Possible Causes for Sepsis, Splenomegaly

  • Infectious Mononucleosis

    Clinical estimates of splenomegaly are fallible.[] This is of particular importance in the pediatric population, which is at higher risk for postsplenectomy sepsis.[] All patients who have the spleen removed are at risk for the postsplenectomy sepsis. These patients need to be monitored closely.[]

  • Upper Respiratory Infection

    Approximately half of EBV mononucleosis cases involve generalized adenopathy or splenomegaly. An enlarged liver may also be palpable.[] Haemophilus influenzae b sepsis with pneumonia B.[] Lower respiratory tract disease and sepsis represent serious complications, especially in patients with immunocompromise.[]

  • Pharyngitis

    It is characterised by : Sore throat Fever Enlarged cervical lymph nodes Enlarged tonsils and fatigue Other clinical manifestations are splenomegaly (enlarged spleen), hepatomegaly[] Upon hospital presentation, the patient was admitted and rapidly progressed to sepsis and respiratory failure.[] Splenomegaly and/or hepatomegaly can be present in more than 50% of patients.[]

  • Typhus

    The most common CT finding was hepatomegaly (74.4%), followed by splenomegaly (66.7%).[] We report an unusual case of scrub typhus in a patient in Singapore who presented with sepsis and acute respiratory distress syndrome but lacked the pathognomonic eschar.[] Low serum albumin and elevated procalcitonin, consistent with bacterial sepsis, were observed in 70% of cases.[]

  • Chronic Lymphocytic Leukemia

    In the physical examination, generalized lymphadenopathy and hepato- and/or splenomegaly may be noted.[] Brentuximab vedotin had a transient effect, but the patient died of sepsis due to residual PTCL and pancytopenia.[] Infections: Infection, including pneumonia, sepsis, septic shock, hepatitis and death have occurred.[]

  • Infective Endocarditis

    This score includes clinical, epidemiological (male, fever, splenomegaly, clubbing, vascular disease and stroke) and biological criteria (Leucocytes 10,000/mm3, sedimentation[] She was admitted presently due to the symptoms of septicemia.[] Patients with SRL lesions were mainly men (P   .01), had liver disease (P   .001) with natural valve (P   .050) and mitro-aortic valve involvement (P   .042), splenomegaly[]

  • Congenital Acquired Immune Deficiency Syndrome

    Category A (mildly symptomatic) - Infants or children that present wth 2 or more of the following: dermatitis, hepatomegaly, splenomegaly, lymphadenopathy ( 2 sites involved[] […] disease, amyotrophic lateral sclerosis, burns, chemotherapy, coeliac disease, corticosteroids, depression and mental stress, IBD, leprosy, NSAIDs, radiation, sarcoidosis, sepsis[] Bacterial infection: severe repeated bacterial infections, such as sepsis, pneumonia, diarrhea, urinary tract infection, skin infections, central nervous system infections[]

  • Malaria

    We report the case of a 12-year-old child who was admitted to our Department, with 7 days' history of high fever and splenomegaly.[] Neonates with congenital malaria may present with non-specific signs and symptoms which may be mistaken for neonatal sepsis and inborn error of metabolism resulting in delay[] Hyperreactive malarial splenomegaly (also called “tropical splenomegaly syndrome”) occurs infrequently and is attributed to an abnormal immune response to repeated malarial[]

  • Mantle Cell Lymphoma

    Fatigue, generalized lymphadenopathy and splenomegaly are its typical features.[] There were three treatment-related deaths during the study, two due to sepsis and one due to embolic stroke.[] A baseline F-FDG PET/CT scan in a patient with mantle cell lymphoma showed diffuse minimally FDG-avid lymphadenopathy and splenomegaly.[]

  • Disseminated Histoplasmosis

    This case highlights consideration of disseminated histoplasmosis in patients presenting with diffuse adenopathy along with hepatomegaly and/or splenomegaly in the right clinical[] The ratio in patients with bacterial sepsis was 0.84.[] On the basis of a comparative analysis of those who died and survived, the absence of splenomegaly and hepatomegaly and the presence of H. capsulatum in the peripheral blood[]

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