Serositis: Causes & Reasons

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Possible Causes for Serositis

Systemic Lupus Erythematosus

ESRp, serositis, and anti-dsDNA antibodies were related to disease activity regardless of infections. [ncbi.nlm.nih.gov]

CONCLUSIONS: We describe a rare case of pericardial mesothelioma in a patient with a clinical presentation compatible with lupus serositis. [ncbi.nlm.nih.gov]

The prevalence of serositis was also higher and photosensitivity less. [doi.org]

Systemic Juvenile Idiopathic Arthritis

Appearance of rash, hepatosplenomegaly, serositis and generalized lymphadenopathy. [symptoma.com]

Minor criteria get 1 point each and include: Onset age < 35 yrs.; prodromal sore throat; serositis; RES involvement (lymphadenopathy, hepatosplenomegaly or increased LFT’s [rheumnow.com]

It is distinguished from other forms of JIA by extra-articular symptoms such as fever, hepatosplenomegaly, lymphadenopathy and serositis. [symptoma.com]

Adult-Onset Still Disease

Minor criteria get 1 point each and include: Onset age < 35 yrs.; prodromal sore throat; serositis; RES involvement (lymphadenopathy, hepatosplenomegaly or increased LFT’s [rheumnow.com]

Although less severe systemic manifestations, like serositis and pneumonitis, were observed, reversible liver involvement was common; the frequency of recurrent disease and [ncbi.nlm.nih.gov]

Other common features are leukocytosis, thrombocy-tosis, elevations of the serum hepatic aminotransferase concentrations, splenomegaly, and serositis. [link.springer.com]

Familial Mediterranean Fever

Familial Mediterranean fever (FMF) is an autosomal recessive disorder characterized by periodic fever and serosal inflammation. [ncbi.nlm.nih.gov]

Familial Mediterranean fever (FMF) is a genetic autoinflammatory disorder that usually develops before 20 years of age and is characterized by periodic fever with serositis [ncbi.nlm.nih.gov]

Familial Mediterranean fever (FMF) is a disorder characterized by recurrent attacks of fever and serosal inflammation, particularly abdominal pain. [ncbi.nlm.nih.gov]

Polyserositis

* * * poly·se·ro·si·tis (pol″e-sēr″o-siґtis) [ poly- + serositis ] general inflammation of serous membranes with serous effusion; see also Concato disease. [medicine.academic.ru]

Treatment of systemic lupus erythematosus-serositis. In: Current diagnosis and treatment: rheumatology. New York: McGraw-Hill; 2013. [jmedicalcasereports.biomedcentral.com]

Allgemeinerkrankung auf wie Tuberkulose, Toxoplasmose, Lupus erythematodes und Polyarthritis[1].… … Deutsch Wikipedia polyserositis — “+ noun Etymology: New Latin, from poly + serositis [medicine.academic.ru]

Whipple Disease

Cardinal Findings: Diarrhea, steatorrhea, weight loss, fever, arthritis, serositis, and lymphadenopathy are seen. [rheumaknowledgy.com]

Other findings include increased skin pigmentation, anemia, lymphadenopathy, chronic cough, serositis, peripheral edema, and CNS symptoms. [merckmanuals.com]

Other findings include increased skin pigmentation, anemia, lymphadenopathy, chronic cough, serositis, peripheral edema, and central nervous system symptoms. [merckmanuals.com]

Chronic Kidney Insufficiency

Uremic serositis is a syndrome of pericarditis, pleural effusion, and sometimes ascites in any combination. [meddean.luc.edu]

Eosinophilic Gastroenteritis

Serosal form is one subtype of EG. The aetiology and pathogenesis of EG are unknown and the diagnosis and treatment properly are difficult for physician. [ncbi.nlm.nih.gov]

Here we are reporting a 40 years old male who presented to us with eosinophilic ascites, a rare presentation of serosal variant of eosinophilic gastroenteritis (EGED). [ncbi.nlm.nih.gov]

[…] occur in the serosal type as well[17]. [wjgnet.com]

Eosinophilic Gastritis

[…] disease; mucosal biopsies may be normal when disease is primarily mural or serosal Ascites with eosinophilia may occur with serosal disease Often have positive skin tests [pathologyoutlines.com]

Histology showed eosinophilic gastritis infiltrating the muscular and serosal layers of the pylorus and antrum. [ncbi.nlm.nih.gov]

IgE Stomach most common site, but primary eosinophilic gastritis without involvement of esophagus or duodenum is uncommon; symptoms relate to site Either mucosal, mural or serosal [pathologyoutlines.com]

Lupus Erythematosus

We present a case of a male black patient with SLE who presented with neurolupus, serositis, skin manifestations and Class IV/V lupus nephritis on histology. [ncbi.nlm.nih.gov]

[…] function and reduction in parotid gland swelling during the postoperative follow-up period, after 7 months of the gastrectomy, anti-DNA antibody levels were increased and serositis [ncbi.nlm.nih.gov]

Treatments for mild to moderate serositis or arthritis include hydroxychloroquine, non-steroidal anti-inflammatory drugs, or corticosteroids. [bestpractice.bmj.com]

Drug-Induced Lupus Erythematosus

To our knowledge this is the first reported case of TMP/SMX-induced DILE presenting with life-threatening serositis. [ncbi.nlm.nih.gov]

The common features were fever, arthralgia, myalgia, serositis, and the presence of anti-histone autoantibodies. [ncbi.nlm.nih.gov]

Findings include skin manifestations, arthritis, serositis, anti-nuclear and anti-histone antibodies positivity. [ncbi.nlm.nih.gov]

Malignant Mesothelioma

Differential diagnoses of serosal-based lesions are fully discussed and the use of immunohistochemical stains is explained. [springer.com]

Malignant mesothelioma is a diffuse tumor arising in the pleura, peritoneum, or other serosal surface and is closely associated with asbestos exposure. [ncbi.nlm.nih.gov]

Abstract Malignant mesothelioma is a diffuse tumor arising in the pleura, peritoneum, or other serosal surface and is closely associated with asbestos exposure. [joi.jlc.jst.go.jp]

Familial Pericarditis

Abstract Familial Mediterranean fever (FMF) is characterized by recurrent attacks of febrile serositis. [ncbi.nlm.nih.gov]

Cassar Demarco, Daniela ; Coleiro, Bernard ; Mallia, Carmel Date: 2015 Abstract: Familial Mediterranean Fever (FMF) is a condition characterized by recurrent febrile poly-serositis [um.edu.mt]

Serositis —Inflammation of a serosal membrane (any membrane that lines a body cavity that does not open to the outside of the body). [healthofchildren.com]

Amyloidosis in Familial Mediterranean Fever

FMF is characterized by sporadic, paroxysmal attacks of fever and serosal inflammation, lasting 1-3 days. Patients may develop renal amyloidosis. [ingentaconnect.com]

Serositis — Inflammation of a serosal membrane. Polyserositis refers to the inflammation of two or more serosal membranes. [medical-dictionary.thefreedictionary.com]

Serositis —Inflammation of a serosal membrane (any membrane that lines a body cavity that does not open to the outside of the body). [healthofchildren.com]

Tumor Necrosis Factor Receptor 1-associated Periodic Syndrome

Serosal inflammation (pleuritis, peritonitis) is common. Abdominal pain and arthralgias are frequent symptoms. [orpha.net]

Clinically, episodes of severe myalgia, arthralgia/arthritis, sterile peritonitis, scrotal inflammation, serositis, migratory rash, conjunctivitis, and recurrent fever are [jrheum.org]

Malignant Peritoneal Mesothelioma

Double-contrast radiography revealed transverse ridging with convergence, suggesting a serosal lesion. [ncbi.nlm.nih.gov]

Interestingly, MM in the setting of endometriosis has only been observed in the peritoneum and not in other serosal cavities. [ncbi.nlm.nih.gov]

It is a tumour that arises from the mesothelium of a serosal cavity. [ncbi.nlm.nih.gov]

Libman-Sacks Disease

[…] chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal [hon.ch]

Systemic Lupus Erythematosus with Organ/System Involvement

0.05), which was characterized by a mild disease with infrequent major organ involvement compared to cluster 2, which had the highest frequency of nephritis, renal failure, serositis [ncbi.nlm.nih.gov]

However, children were also treated for other disease manifestations, including cytopenia, vasculitis, arthritis, serositis, neuropsychiatric disease, skin disorders, pulmonary [the-rheumatologist.org]

[…] which was significantly elevated in patients with serositis (5.7±1.99 MPLU) than those without (4.2±1.68 MPLU) (p< 0.05). [scialert.net]

Pneumatosis Cystoides Intestinalis

The resected segment of the bowel showed multiple thin walled, tense, air-filled cysts on the serosal surface, which collapsed with a popping sound when pricked. [ncbi.nlm.nih.gov]

Rupture of colon Rupture of ileum Rupture of intestine Rupture of small intestine Sepsis-related gastrointestinal lesions Serositis Severe systemic illness-induced intestinal [icd9data.com]

Pneumatosis cystoides intestinalis (PCI) is defined as the presence of gas-containing cysts in the submucosal and serosal layers of the small and large bowel. [scielo.isciii.es]

Endometriosis of the Colon

BACKGROUND: Although endometriosis with sigmoid serosal involvement is not uncommon in women of childbearing age, the mucosal involvement is rare and differential diagnosis [ncbi.nlm.nih.gov]

The masses involve the serosal surface. [ispub.com]

Typically incidental but can cause pain, obstruction or diarrhea Rarely associated with neoplasms or precancerous changes ( Am J Surg Pathol 2000;24:513 ) Gross description Serosal [pathologyoutlines.com]

Familial Cold Autoinflammatory Syndrome Type 1

Amyloidosis, arthritis are uncommon while deafness, lymphadenopathy, and serositis are absent Etiology FCAS is caused by gain-of-function point mutations in the NLRP3 gene [orpha.net]

but also conjunctivitis when exposed to cold environments, resolution of symptoms within 24 hours of their onset, together with absence of deafness, periorbital edema, serositis [symptoma.com]

[…] periorbital edema (swelling around the eye orbit), lymphadenopathy (enlarged lymph nodes), or inflammation of the pleural, peritoneal or pericardial cavities in the body (serositis [autoinflammatory.org]

Eosinophilic Peritonitis

Ascites fluid is usually detected in patients with serosal layer involvement. [emj.bmj.com]

It can be classified into mucosal, muscular and serosal subtypes based on the involved layer of the intestinal wall [ 5 ]. [omicsonline.org]

[…] peritonitis NOS due to urine K65.8 eosinophilic K65.8 chronic proliferative K65.8 proliferative, chronic K65.8 specified NEC K65.8 urine K65.8 Saponification, mesenteric K65.8 Serositis [icd10data.com]

Peritoneal Disease

As a result of serosal effusion and diffuse serosal thickening by tumor, patients with pleural tumors typically present with chest pain and shortness of breath and abdominal [oxfordscholarship.com]

The same can be told for other serosal surfaces of human body, like pericardium and pleura. [jperitoneum.org]

Chapter: (p.190) 8 Malignant Diseases of the Pleura, Peritoneum, and Other Serosal Surfaces Source: Asbestos and Its Diseases Allen R. Gibbs John E. [oxfordscholarship.com]

Splenosis

Implants can be found anywhere in the peritoneal cavity, especially on the serosal surfaces of small and large bowel, in the mesentery and diaphragm, implanted in visceral [ncbi.nlm.nih.gov]

Implantation and subsequent growth of splenic tissue within the abdomen as a result of disruption of the spleen. splenosis widespread seeding of splenic implants on the serosal [medical-dictionary.thefreedictionary.com]

They are typically small, sessile (as they grow on serosal/peritoneal surfaces) and multiple. They may grow overtime to become quite sizeable. [radiopaedia.org]

Idiopathic Recurrent Pericarditis

[…] or intolerant to therapy. 2–4 This disease is currently viewed as an autoinflammatory disease based on its clinical and laboratory features (recurrent episodes of sterile serosal [ard.bmj.com]

Autoinflammatory diseases, as proposed by experts ( 7, 8 ), are characterized by recurrent episodes of sterile inflammation in different target organs (most commonly skin, serosal [journal.frontiersin.org]

Serositis related to systemic lupus erythematosus: prevalence and outcome. Lupus. 2005; 14: 822-6 M Imazio, A Brucato, R Trinchero, D Spodick and Y Adler. [gilp.org]

Acute Pleuropericarditis

Serositis directly related to IBD is a diagnosis of exclusion. [utsouthwestern.influuent.utsystem.edu]

Abstract Serositis is a rare manifestation of chronic GvHD (cGvHD). [nature.com]

Tucker et al. [9] reported the clinical range of serositis with autoimmune endocrinopathy in their 20 patients. [cureus.com]

Linitis Plastica

Because the mucosal and serosal layers remained intact, diagnosis was markedly delayed, as is commonly seen in scirrhous carcinoma. [ncbi.nlm.nih.gov]

This decision is based on the fact that there is early serosal and lymph-node involvement, a high incidence of ovarian metastasis and absence of hepatic metastasis. [insights.ovid.com]

Lupus Encephalitis

[…] chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal [fpnotebook.com]

Chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal [icd10data.com]

Serositis NSAIDs Moderate steroids Hydroxychloroquine Steroid sparing 22. Cutaneous manifestations of Lupus 23. [slideshare.net]

Allergic Gastritis

[…] following patterns Predominantly mucosal Infiltrates epithelium and may form crypt abscesses Predominantly mural or transmural, involving muscularis propria Predominantly serosal [surgpathcriteria.stanford.edu]

In patients, manifestations of their diseases are based on histologic involvement: mucosal, muscularis, or serosal forms. [1] Any layer of the GI tract can be involved. [emedicine.medscape.com]

Mesothelioma

Abstract Malignant mesothelioma is a diffuse tumor arising in the pleura, peritoneum, or other serosal surface and is closely associated with asbestos exposure. [doi.org]

[…] co-factors in the pathogenesis of asbestos-related mesothelioma include genetic predisposition, diets poor in fruit and vegetables, viruses, immune impairment, recurrent serosal [ncbi.nlm.nih.gov]