Possible Causes for Serositis Systemic Lupus Erythematosus ESRp, serositis, and anti-dsDNA antibodies were related to disease activity regardless of infections. [ncbi.nlm.nih.gov] CONCLUSIONS: We describe a rare case of pericardial mesothelioma in a patient with a clinical presentation compatible with lupus serositis. [ncbi.nlm.nih.gov] Treatments for mild to moderate serositis or arthritis include hydroxychloroquine, non-steroidal anti-inflammatory drugs, or corticosteroids. [bestpractice.bmj.com] Systemic Juvenile Idiopathic Arthritis Minor criteria get 1 point each and include: Onset age < 35 yrs.; prodromal sore throat; serositis; RES involvement (lymphadenopathy, hepatosplenomegaly or increased LFT’s [rheumnow.com] Appearance of rash, hepatosplenomegaly, serositis and generalized lymphadenopathy. [symptoma.com] Other characteristic manifestations include a prodromal sore throat, arthralgias, myalgias, weight loss, serositis, hepatomegaly (often with elevated hepatic enzymes), splenomegaly [rheumnow.com] Familial Mediterranean Fever Serositis — Inflammation of a serosal membrane. Polyserositis refers to the inflammation of two or more serosal membranes. [medical-dictionary.thefreedictionary.com] vasculitis, lymphadenopathy, organ inflammation/damage Adverse reactions Relieve fever, rash; improve adenopathy, arthritis; lessen organ involvement, serositis Colchicine [clinicaladvisor.com] Familial Mediterranean fever (FMF) is an autosomal recessive disorder characterized by periodic fever and serosal inflammation. [ncbi.nlm.nih.gov] Adult-Onset Still Disease Although less severe systemic manifestations, like serositis and pneumonitis, were observed, reversible liver involvement was common; the frequency of recurrent disease and [ncbi.nlm.nih.gov] Minor criteria get 1 point each and include: Onset age < 35 yrs.; prodromal sore throat; serositis; RES involvement (lymphadenopathy, hepatosplenomegaly or increased LFT’s [rheumnow.com] CRP, white count, and hyperferritinemia (69-97% of patients) -Other findings that may be found include: myalgia, sore throat, hepatomegaly, splenomegaly, lymphadenopathy, serositis [utswim.wordpress.com] Polyserositis * * * poly·se·ro·si·tis (pol″e-sēr″o-siґtis) [ poly- + serositis ] general inflammation of serous membranes with serous effusion; see also Concato disease. [medicine.academic.ru] Treatment of systemic lupus erythematosus-serositis. In: Current diagnosis and treatment: rheumatology. New York: McGraw-Hill; 2013. [jmedicalcasereports.biomedcentral.com] Allgemeinerkrankung auf wie Tuberkulose, Toxoplasmose, Lupus erythematodes und Polyarthritis[1].… … Deutsch Wikipedia polyserositis — “+ noun Etymology: New Latin, from poly + serositis [medicine.academic.ru] Whipple Disease Cardinal Findings: Diarrhea, steatorrhea, weight loss, fever, arthritis, serositis, and lymphadenopathy are seen. [rheumaknowledgy.com] Other findings include increased skin pigmentation, anemia, lymphadenopathy, chronic cough, serositis, peripheral edema, and central nervous system symptoms. [msdmanuals.com] Other findings include increased skin pigmentation, anemia, lymphadenopathy, chronic cough, serositis, peripheral edema, and CNS symptoms. [merckmanuals.com] Chronic Kidney Insufficiency Uremic serositis is a syndrome of pericarditis, pleural effusion, and sometimes ascites in any combination. [meddean.luc.edu] Eosinophilic Gastroenteritis Serosal form is one subtype of EG. The aetiology and pathogenesis of EG are unknown and the diagnosis and treatment properly are difficult for physician. [ncbi.nlm.nih.gov] Sonographic visualization of nodular peritoneal deposits associated with eosinophilic ascites permitted the diagnosis of the serosal form of eosinophilic gastroenteritis. [ncbi.nlm.nih.gov] […] disease; mucosal biopsies may be normal when disease is primarily mural or serosal Ascites with eosinophilia may occur with serosal disease Often have positive skin tests [pathologyoutlines.com] Eosinophilic Gastritis […] disease; mucosal biopsies may be normal when disease is primarily mural or serosal Ascites with eosinophilia may occur with serosal disease Often have positive skin tests [pathologyoutlines.com] Histology showed eosinophilic gastritis infiltrating the muscular and serosal layers of the pylorus and antrum. [ncbi.nlm.nih.gov] IgE Stomach most common site, but primary eosinophilic gastritis without involvement of esophagus or duodenum is uncommon; symptoms relate to site Either mucosal, mural or serosal [pathologyoutlines.com] Lupus Erythematosus Treatments for mild to moderate serositis or arthritis include hydroxychloroquine, non-steroidal anti-inflammatory drugs, or corticosteroids. [bestpractice.bmj.com] We present a case of a male black patient with SLE who presented with neurolupus, serositis, skin manifestations and Class IV/V lupus nephritis on histology. [ncbi.nlm.nih.gov] In addition to constitutional symptoms, it most frequently involves the skin and joints, although serositis, nephritis, haematological cytopenias, and neurological manifestations [bestpractice.bmj.com] Drug-Induced Lupus Erythematosus The common features were fever, arthralgia, myalgia, serositis, and the presence of anti-histone autoantibodies. [ncbi.nlm.nih.gov] To our knowledge this is the first reported case of TMP/SMX-induced DILE presenting with life-threatening serositis. [ncbi.nlm.nih.gov] Findings include skin manifestations, arthritis, serositis, anti-nuclear and anti-histone antibodies positivity. [ncbi.nlm.nih.gov] Familial Pericarditis Abstract Familial Mediterranean fever (FMF) is characterized by recurrent attacks of febrile serositis. [ncbi.nlm.nih.gov] Cassar Demarco, Daniela ; Coleiro, Bernard ; Mallia, Carmel Date: 2015 Abstract: Familial Mediterranean Fever (FMF) is a condition characterized by recurrent febrile poly-serositis [um.edu.mt] Serositis —Inflammation of a serosal membrane (any membrane that lines a body cavity that does not open to the outside of the body). [healthofchildren.com] Libman-Sacks Disease […] chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal [hon.ch] Amyloidosis in Familial Mediterranean Fever FMF is characterized by sporadic, paroxysmal attacks of fever and serosal inflammation, lasting 1-3 days. Patients may develop renal amyloidosis. [ingentaconnect.com] Serositis — Inflammation of a serosal membrane. Polyserositis refers to the inflammation of two or more serosal membranes. [medical-dictionary.thefreedictionary.com] Serositis —Inflammation of a serosal membrane (any membrane that lines a body cavity that does not open to the outside of the body). [healthofchildren.com] Tumor Necrosis Factor Receptor 1-associated Periodic Syndrome Clinically, episodes of severe myalgia, arthralgia/arthritis, sterile peritonitis, scrotal inflammation, serositis, migratory rash, conjunctivitis, and recurrent fever are [jrheum.org] Serosal inflammation (pleuritis, peritonitis) is common. Abdominal pain and arthralgias are frequent symptoms. [orpha.net] Lupus Nephritis WHO Class 1 Less common [3] Hematological: : petechiae;, pallor, or recurrent infections due to cytopenias Musculoskeletal: myalgia Serositis: : pleuritis and pericarditis → effusions [amboss.com] SLE is a systemic autoimmune disease, most commonly involving the skin, kidneys, joints, heart, and serosal surfaces. [ajkd.org] Symptoms of active systemic lupus erythematosus (SLE), including fatigue, fever, rash, arthritis, serositis, or central nervous system (CNS) disease. 3. [slideshare.net] Lupus Nephritis WHO Class 6 There is a consensus that oral corticosteroids are effective in the management of joint symptoms, fatigue, and serositis in persons with SLE. [aafp.org] Symptoms of active systemic lupus erythematosus (SLE), including fatigue, fever, rash, arthritis, serositis, or central nervous system (CNS) disease. 3. [slideshare.net] Common manifestations, in addition to the malar rash, include cutaneous photosensitivity, nephropathy, serositis, and polyarthritis. [physio-pedia.com] Malignant Peritoneal Mesothelioma Double-contrast radiography revealed transverse ridging with convergence, suggesting a serosal lesion. [ncbi.nlm.nih.gov] Interestingly, MM in the setting of endometriosis has only been observed in the peritoneum and not in other serosal cavities. [ncbi.nlm.nih.gov] Neoplastic and non-neoplastic conditions of serosal membrane origin: CT findings. Radiographics. 2008;28(3):801–17. Article | PubMed Chua TC, Chong CH, Morris DL. [acgcasereports.gi.org] Endometriosis of the Colon BACKGROUND: Although endometriosis with sigmoid serosal involvement is not uncommon in women of childbearing age, the mucosal involvement is rare and differential diagnosis [ncbi.nlm.nih.gov] Typically incidental but can cause pain, obstruction or diarrhea Rarely associated with neoplasms or precancerous changes ( Am J Surg Pathol 2000;24:513 ) Gross description Serosal [pathologyoutlines.com] The masses involve the serosal surface. [ispub.com] Peritoneal Disease As a result of serosal effusion and diffuse serosal thickening by tumor, patients with pleural tumors typically present with chest pain and shortness of breath and abdominal [oxfordscholarship.com] The same can be told for other serosal surfaces of human body, like pericardium and pleura. [jperitoneum.org] Chapter: (p.190) 8 Malignant Diseases of the Pleura, Peritoneum, and Other Serosal Surfaces Source: Asbestos and Its Diseases Allen R. Gibbs John E. [oxfordscholarship.com] Familial Cold Autoinflammatory Syndrome Type 1 Amyloidosis, arthritis are uncommon while deafness, lymphadenopathy, and serositis are absent Etiology FCAS is caused by gain-of-function point mutations in the NLRP3 gene [orpha.net] […] periorbital edema (swelling around the eye orbit), lymphadenopathy (enlarged lymph nodes), or inflammation of the pleural, peritoneal or pericardial cavities in the body (serositis [autoinflammatory.org] Malignant Mesothelioma Malignant mesothelioma is a diffuse tumor arising in the pleura, peritoneum, or other serosal surface and is closely associated with asbestos exposure. [ncbi.nlm.nih.gov] Abstract Malignant mesothelioma is a diffuse tumor arising in the pleura, peritoneum, or other serosal surface and is closely associated with asbestos exposure. [doi.org] Systemic Lupus Erythematosus with Organ/System Involvement 0.05), which was characterized by a mild disease with infrequent major organ involvement compared to cluster 2, which had the highest frequency of nephritis, renal failure, serositis [ncbi.nlm.nih.gov] However, children were also treated for other disease manifestations, including cytopenia, vasculitis, arthritis, serositis, neuropsychiatric disease, skin disorders, pulmonary [the-rheumatologist.org] “serositis”). [ncbi.nlm.nih.gov] Eosinophilic Peritonitis Ascites fluid is usually detected in patients with serosal layer involvement. [emj.bmj.com] It can be classified into mucosal, muscular and serosal subtypes based on the involved layer of the intestinal wall [ 5 ]. [omicsonline.org] […] peritonitis NOS due to urine K65.8 eosinophilic K65.8 chronic proliferative K65.8 proliferative, chronic K65.8 specified NEC K65.8 urine K65.8 Saponification, mesenteric K65.8 Serositis [icd10data.com] Pneumatosis Cystoides Intestinalis The resected segment of the bowel showed multiple thin walled, tense, air-filled cysts on the serosal surface, which collapsed with a popping sound when pricked. [ncbi.nlm.nih.gov] Rupture of colon Rupture of ileum Rupture of intestine Rupture of small intestine Sepsis-related gastrointestinal lesions Serositis Severe systemic illness-induced intestinal [icd9data.com] As a rare benign complication, patients with PCI may develop pneumoperitoneum when rupture of serosal cysts occurs. [videogie.org] Acute Pleuropericarditis Abstract Serositis is a rare manifestation of chronic GvHD (cGvHD). [nature.com] Serositis directly related to IBD is a diagnosis of exclusion. [utsouthwestern.influuent.utsystem.edu] Tucker et al. [9] reported the clinical range of serositis with autoimmune endocrinopathy in their 20 patients. [cureus.com] Idiopathic Recurrent Pericarditis […] or intolerant to therapy. 2–4 This disease is currently viewed as an autoinflammatory disease based on its clinical and laboratory features (recurrent episodes of sterile serosal [ard.bmj.com] Serositis related to systemic lupus erythematosus: prevalence and outcome. Lupus. 2005; 14: 822-6 M Imazio, A Brucato, R Trinchero, D Spodick and Y Adler. [gilp.org] […] represents an autoinflammatory disease due to a genetically determined dysfunction of the innate immune system that causes a dysregulation of the inflammatory process. 22, 23 Serosal [pediatrics.aappublications.org] Abdominal Visceral Abscess […] mm of serosal reaction) and 55% T4 tumors. [nature.com] The extraperitoneal tissue external to the parietal peritoneum is carried with the reflections to the organs and becomes a part of the serosal layer. [dartmouth.edu] Pathophysiology of abdominal pain: — Neurologic basis for abdominal pain – Stretch is the primary mechanical stimulus of the visceral receptors located on serosal surfaces [medical-institution.com] Splenosis Implants can be found anywhere in the peritoneal cavity, especially on the serosal surfaces of small and large bowel, in the mesentery and diaphragm, implanted in visceral [ncbi.nlm.nih.gov] Implantation and subsequent growth of splenic tissue within the abdomen as a result of disruption of the spleen. splenosis widespread seeding of splenic implants on the serosal [medical-dictionary.thefreedictionary.com] Abdominal splenosis occurs throughout the abdominal cavity but the most common sites in order of frequency are the serosal surface of the bowel, the greater omentum, the parietal [bhj.org.in] Allergic Gastritis […] disease; mucosal biopsies may be normal when disease is primarily mural or serosal Ascites with eosinophilia may occur with serosal disease Often have positive skin tests [pathologyoutlines.com] […] following patterns Predominantly mucosal Infiltrates epithelium and may form crypt abscesses Predominantly mural or transmural, involving muscularis propria Predominantly serosal [surgpathcriteria.stanford.edu] In patients, manifestations of their diseases are based on histologic involvement: mucosal, muscularis, or serosal forms. [1] Any layer of the GI tract can be involved. [emedicine.medscape.com]
