Possible Causes for serositis Chronic Kidney Insufficiency Uremic serositis is a syndrome of pericarditis, pleural effusion, and sometimes ascites in any combination. [meddean.luc.edu] Systemic Lupus Erythematosus ESRp, serositis, and anti-dsDNA antibodies were related to disease activity regardless of infections. [ncbi.nlm.nih.gov] CONCLUSIONS: We describe a rare case of pericardial mesothelioma in a patient with a clinical presentation compatible with lupus serositis. [ncbi.nlm.nih.gov] The prevalence of serositis was also higher and photosensitivity less. [doi.org] Juvenile-Onset Still Disease Appearance of rash, hepatosplenomegaly, serositis and generalized lymphadenopathy. [symptoma.com] JIA and is considered by many to be the most severe JIA subtype. sJIA typically presents with fever of unknown origin and arthritis, together with evanescent skin rash, serositis [clinicaltrials.gov] […] following manifestations: skin rash (evanescent, non-fixed erythematous rash that accompanies fever spikes), generalized lymphadenopathy, hepatomegaly and/or splenomegaly, or serositis [stillsdisease.org] Adult-Onset Still Disease Although less severe systemic manifestations, like serositis and pneumonitis, were observed, reversible liver involvement was common; the frequency of recurrent disease and [ncbi.nlm.nih.gov] Minor criteria get 1 point each and include: Onset age 35 yrs.; prodromal sore throat; serositis; RES involvement (lymphadenopathy, hepatosplenomegaly or increased LFT’s); [rheumnow.com] sore throat or pharyngitis, arthralgia or arthritis ( 65% of patients), transient maculopapular rash, and more rarely myalgia, lymphadenopathy, hepatosplenomegaly, and serositis [orpha.net] Familial Mediterranean Fever Familial Mediterranean fever (FMF) is an autosomal recessive disorder characterized by periodic fever and serosal inflammation. [ncbi.nlm.nih.gov] Familial Mediterranean fever (FMF) is a genetic autoinflammatory disorder that usually develops before 20 years of age and is characterized by periodic fever with serositis [ncbi.nlm.nih.gov] Familial Mediterranean fever (FMF) is a disorder characterized by recurrent attacks of fever and serosal inflammation, particularly abdominal pain. [ncbi.nlm.nih.gov] Eosinophilic Gastroenteritis Serosal form is one subtype of EG. The aetiology and pathogenesis of EG are unknown and the diagnosis and treatment properly are difficult for physician. [ncbi.nlm.nih.gov] Sonographic visualization of nodular peritoneal deposits associated with eosinophilic ascites permitted the diagnosis of the serosal form of eosinophilic gastroenteritis. [ncbi.nlm.nih.gov] Here we are reporting a 40 years old male who presented to us with eosinophilic ascites, a rare presentation of serosal variant of eosinophilic gastroenteritis (EGED). [ncbi.nlm.nih.gov] Eosinophilic Gastritis Histology showed eosinophilic gastritis infiltrating the muscular and serosal layers of the pylorus and antrum. [ncbi.nlm.nih.gov] […] disease; mucosal biopsies may be normal when disease is primarily mural or serosal Ascites with eosinophilia may occur with serosal disease Often have positive skin tests [pathologyoutlines.com] IgE Stomach most common site, but primary eosinophilic gastritis without involvement of esophagus or duodenum is uncommon; symptoms relate to site Either mucosal, mural or serosal [pathologyoutlines.com] Polyserositis Treatment of systemic lupus erythematosus-serositis. In: Current diagnosis and treatment: rheumatology. New York: McGraw-Hill; 2013. [jmedicalcasereports.biomedcentral.com] Synonym: Bamberger's disease, Concato's disease, multiple serositis. Origin: poly- L. Serum, serum, G. [lexic.us] […] itis, inflammation] polyserositis /poly·se·ro·si·tis/ ( -sēr″ah-si tis ) general inflammation of serous membranes, with effusion. polyserositis Inflammation of multiple serosal [medical-dictionary.thefreedictionary.com] Lupus Erythematosus We present a case of a male black patient with SLE who presented with neurolupus, serositis, skin manifestations and Class IV/V lupus nephritis on histology. [ncbi.nlm.nih.gov] […] function and reduction in parotid gland swelling during the postoperative follow-up period, after 7 months of the gastrectomy, anti-DNA antibody levels were increased and serositis [ncbi.nlm.nih.gov] Treatments for mild to moderate serositis or arthritis include hydroxychloroquine, non-steroidal anti-inflammatory drugs, or corticosteroids. [bestpractice.bmj.com] Drug-Induced Lupus Erythematosus To our knowledge this is the first reported case of TMP/SMX-induced DILE presenting with life-threatening serositis. [ncbi.nlm.nih.gov] The common features were fever, arthralgia, myalgia, serositis, and the presence of anti-histone autoantibodies. [ncbi.nlm.nih.gov] Findings include skin manifestations, arthritis, serositis, anti-nuclear and anti-histone antibodies positivity. [ncbi.nlm.nih.gov] Whipple Disease Cardinal Findings: Diarrhea, steatorrhea, weight loss, fever, arthritis, serositis, and lymphadenopathy are seen. [rheumaknowledgy.com] Other findings include increased skin pigmentation, anemia, lymphadenopathy, chronic cough, serositis, peripheral edema, and CNS symptoms. [merckmanuals.com] Other findings include increased skin pigmentation, anemia, lymphadenopathy, chronic cough, serositis, peripheral edema, and central nervous system symptoms. [merckmanuals.com] Amyloidosis in Familial Mediterranean Fever FMF is characterized by sporadic, paroxysmal attacks of fever and serosal inflammation, lasting 1-3 days. Patients may develop renal amyloidosis. [ingentaconnect.com] Israel eldad{at}hadassah.org.il Abstract BACKGROUND Familial Mediterranean fever (FMF) is an autosomal recessive disease characterised by recurrent attacks of fever and serositis [ard.bmj.com] Serositis — Inflammation of a serosal membrane. Polyserositis refers to the inflammation of two or more serosal membranes. [medical-dictionary.thefreedictionary.com] Familial Pericarditis Abstract Familial Mediterranean fever (FMF) is characterized by recurrent attacks of febrile serositis. [ncbi.nlm.nih.gov] Cassar Demarco, Daniela ; Coleiro, Bernard ; Mallia, Carmel Date: 2015 Abstract: Familial Mediterranean Fever (FMF) is a condition characterized by recurrent febrile poly-serositis [um.edu.mt] Serositis —Inflammation of a serosal membrane (any membrane that lines a body cavity that does not open to the outside of the body). [healthofchildren.com] Tumor Necrosis Factor Receptor 1-associated Periodic Syndrome Serosal inflammation (pleuritis, peritonitis) is common. Abdominal pain and arthralgias are frequent symptoms. [orpha.net] Malignant Peritoneal Mesothelioma Double-contrast radiography revealed transverse ridging with convergence, suggesting a serosal lesion. [ncbi.nlm.nih.gov] Interestingly, MM in the setting of endometriosis has only been observed in the peritoneum and not in other serosal cavities. [ncbi.nlm.nih.gov] It is a tumour that arises from the mesothelium of a serosal cavity. [ncbi.nlm.nih.gov] Malignant Mesothelioma Malignant mesothelioma is a diffuse tumor arising in the pleura, peritoneum, or other serosal surface and is closely associated with asbestos exposure. [ncbi.nlm.nih.gov] Abstract Malignant mesothelioma (MM) is an aggressive malignancy of the pleura and other serosal membranes originating from mesothelial cells that, despite decades of research [ncbi.nlm.nih.gov] Abstract Malignant mesothelioma is a diffuse tumor arising in the pleura, peritoneum, or other serosal surface and is closely associated with asbestos exposure. [doi.org] Pneumatosis Cystoides Intestinalis The resected segment of the bowel showed multiple thin walled, tense, air-filled cysts on the serosal surface, which collapsed with a popping sound when pricked. [ncbi.nlm.nih.gov] Microscopically, the intestinal mucosa appears superficially normal and unbroken, with gas-containing submucosal or sub-serosal sacs, lined with endothelium and containing [pubs.rsna.org] Rupture of colon Rupture of ileum Rupture of intestine Rupture of small intestine Sepsis-related gastrointestinal lesions Serositis Severe systemic illness-induced intestinal [icd9data.com] Linitis Plastica Because the mucosal and serosal layers remained intact, diagnosis was markedly delayed, as is commonly seen in scirrhous carcinoma. [ncbi.nlm.nih.gov] This decision is based on the fact that there is early serosal and lymph-node involvement, a high incidence of ovarian metastasis and absence of hepatic metastasis. [insights.ovid.com] Libman-Sacks Disease […] chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal [hon.ch] Peritoneal Disease As a result of serosal effusion and diffuse serosal thickening by tumor, patients with pleural tumors typically present with chest pain and shortness of breath and abdominal [oxfordscholarship.com] The same can be told for other serosal surfaces of human body, like pericardium and pleura. [jperitoneum.org] Chapter: (p.190) 8 Malignant Diseases of the Pleura, Peritoneum, and Other Serosal Surfaces Source: Asbestos and Its Diseases Allen R. Gibbs John E. [oxfordscholarship.com] Peritoneal Metastasis RESULTS: According to the laparoscopic results, the patients were divided into T1-T2 stage (n 56) without and into T3-T4 stage (n 80) with tumor invasion into the serosal [ncbi.nlm.nih.gov] […] benign disease group, and the positive rate of immunohistochemistry was closely related to the relative factors of peritoneal metastasis such as tumor infiltration depth, serosal [ncbi.nlm.nih.gov] 21, miR-320c, and miR-1225-5p was validated in the PLF of serosa-invasive and non-invasive GC by qRT-PCR and miR-21 and miR-1225-5p were confirmed to be associated with serosal [ncbi.nlm.nih.gov] Systemic Lupus Erythematosus with Organ/System Involvement 0.05), which was characterized by a mild disease with infrequent major organ involvement compared to cluster 2, which had the highest frequency of nephritis, renal failure, serositis [ncbi.nlm.nih.gov] However, children were also treated for other disease manifestations, including cytopenia, vasculitis, arthritis, serositis, neuropsychiatric disease, skin disorders, pulmonary [the-rheumatologist.org] […] which was significantly elevated in patients with serositis (5.7 1.99 MPLU) than those without (4.2 1.68 MPLU) (p 0.05). [scialert.net] Allergic Gastritis […] disease; mucosal biopsies may be normal when disease is primarily mural or serosal Ascites with eosinophilia may occur with serosal disease Often have positive skin tests [pathologyoutlines.com] […] following patterns Predominantly mucosal Infiltrates epithelium and may form crypt abscesses Predominantly mural or transmural, involving muscularis propria Predominantly serosal [surgpathcriteria.stanford.edu] In patients, manifestations of their diseases are based on histologic involvement: mucosal, muscularis, or serosal forms. [1] Any layer of the GI tract can be involved. [emedicine.medscape.com] Familial Cold Autoinflammatory Syndrome Type 1 Amyloidosis, arthritis are uncommon while deafness, lymphadenopathy, and serositis are absent Etiology FCAS is caused by gain-of-function point mutations in the NLRP3 gene [orpha.net] but also conjunctivitis when exposed to cold environments, resolution of symptoms within 24 hours of their onset, together with absence of deafness, periorbital edema, serositis [symptoma.com] […] months; duration of most attacks less than 24 hours; conjunctivitis in association with attacks; and absence of deafness, swelling around the eyes, enlarged lymph nodes, and serositis [rarediseases.info.nih.gov] Mesothelioma Abstract Malignant mesothelioma is a diffuse tumor arising in the pleura, peritoneum, or other serosal surface and is closely associated with asbestos exposure. [doi.org] […] co-factors in the pathogenesis of asbestos-related mesothelioma include genetic predisposition, diets poor in fruit and vegetables, viruses, immune impairment, recurrent serosal [ncbi.nlm.nih.gov] Splenosis Implants can be found anywhere in the peritoneal cavity, especially on the serosal surfaces of small and large bowel, in the mesentery and diaphragm, implanted in visceral [ncbi.nlm.nih.gov] Implantation and subsequent growth of splenic tissue within the abdomen as a result of disruption of the spleen. splenosis widespread seeding of splenic implants on the serosal [medical-dictionary.thefreedictionary.com] They are typically small, sessile (as they grow on serosal/peritoneal surfaces) and multiple. They may grow overtime to become quite sizeable. [radiopaedia.org] Drug-induced Fever Symptoms may include fatigue, fever, joint pains, arthritis, rash, muscle aches, and serositis. [clinicaladvisor.com] Patients typically experience arthralgia, arthritis, myalgia, and serositis. 1,2,7 TABLE 1 provides a description of the clinical characteristics of DIL. 2,7,8 Arthralgia [uspharmacist.com] History Part I: Pattern Recognition: Patients with drug-induced lupus often experience myalgias, arthralgias, fever, serositis, and cutaneous manifestations such as purpura [clinicaladvisor.com] Lupus Encephalitis […] antibodies Chronic cutaneous lupus Anti-DNA Oral or nasal ulcers Anti-Smith antibodies Nonscarring alopecia Antiphospholipid antibodies Arthritis Low complement (C3, C4, CH50) Serositis [healio.com] […] chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal [fpnotebook.com] […] or mouth, usually painless Arthritis Nonerosive arthritis involving two or more peripheral joints arthritis in which the bones around the joints do not become destroyed Serositis [sarahwang.club] Endometriosis of the Colon BACKGROUND: Although endometriosis with sigmoid serosal involvement is not uncommon in women of childbearing age, the mucosal involvement is rare and differential diagnosis [ncbi.nlm.nih.gov] The masses involve the serosal surface. [ispub.com] Areas of necrosis were present and there was extensive lymphovascular permeation, both within the tumour and within submucosal and serosal lymphatics away from the tumour. [jcp.bmj.com] Lupus Nephritis We present a case of a male black patient with SLE who presented with neurolupus, serositis, skin manifestations and Class IV/V lupus nephritis on histology. [ncbi.nlm.nih.gov] We present a case of a 49-year-old female with an atypical presentation of LN who initially presented with new-onset hypertension, edema, arthritis, serositis and recently [ncbi.nlm.nih.gov] In clinical data, photosensitivity and mouth ulcers were more common in the female patients, while males had more serositis and vasculitis. [ncbi.nlm.nih.gov]
