Severe Anemia Causes & Reasons

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Severe Anemia Symptom Checker: Possible causes include Iron Deficiency. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.

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Possible Causes

Iron Deficiency

When severe, anemia may cause shortness of breath, dizziness, and a rapid heart rate. Occasionally, severe anemia causes chest pain and heart failure. [merckmanuals.com]

While there are several causes of anemia, iron deficiency is the most common. [americanpregnancy.org]

anemia, according to a University of Rochester Medical Center study published in the scientific journal PLoS One. [urmc.rochester.edu]

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Anemia

All publications report a positive result when HBO2 is delivered as treatment for severe anemia. [archive.rubicon-foundation.org]

If anemia is slowly ongoing (chronic), the body may adapt and compensate for the change; in this case there may not be any symptoms until the anemia becomes more severe. [web.archive.org]

Herein, we report an unusual case of severe anemia complicating cardiac transplantation. [ncbi.nlm.nih.gov]

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Iron Deficiency Anemia

OBJECTIVE: To evaluate the proportion of children with moderate to severe iron-deficiency anemia who have associated celiac disease. [ncbi.nlm.nih.gov]

Heavy menstrual bleeding (menorrhagia) and pregnancy and delivery can cause significant iron loss leading to severe anemia The aim of the present study was to characterize [ncbi.nlm.nih.gov]

An adolescent male presented with recurrent episodes over several years of severe iron deficiency anemia and associated severe thrombocytopenia. [ncbi.nlm.nih.gov]

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Hemolytic Anemia

Severe hemolytic anemia (HA) is an uncommon adverse reaction of intravenous immunoglobulin (IVIg) administration. [ncbi.nlm.nih.gov]

CONCLUSIONS: C. perfringens infection should be considered in a febrile patient who has severe hemolytic anemia with a very low MCV, hemolyzed blood sample, and negative Coombs [ncbi.nlm.nih.gov]

We also found that the severity of anemia was significantly greater with G6PD Med and G6PD Cairo than with G6PD A-; and with G6PD Cairo, compared to the other two variants [ncbi.nlm.nih.gov]

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Hypoxia

anemia Chronic lung disease, such as emphysema Congestive heart failure What are the signs and symptoms of hypoxia? [drugs.com]

Pure cerebral hypoxia can occur due to pulmonary disease, altitude sickness, or severe anemia. [encyclopedia.com]

Acute hypoxia is often a result of acute hemolysis with severe anemia resulting in reduced oxygen content in blood. [bloodjournal.org]

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Pernicious Anemia

INTRODUCTION To our knowledge, there are no reported cases of severe pernicious anemia predisposing to hypoxic hepatitis (HH). [journals.lww.com]

Here, we report a rare coincidence of heterozygous hemoglobinopathy (Hb) Stanleyville II and severe pernicious anemia due to autoimmune gastritis. [ncbi.nlm.nih.gov]

We report a case of severe megaloblastic anemia due to pernicious anemia in which initial screening studies appeared to exclude B12 deficiency. [academic.oup.com]

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Aplastic Anemia

OVERVIEW: What every practitioner needs to know about severe aplastic anemia Are you sure your patient has severe aplastic anemia? [clinicaladvisor.com]

Aplastic Anemia Survival Over Time, Unrelated HCT Figure 2: Pediatric Severe Aplastic Anemia Survival Over Time, Unrelated HCT Figure 3: Severe Aplastic Anemia Survival, [bethematchclinical.org]

Recently the stem cells from cord blood have been used for the treatment of severe aplastic anemia following acute liver failure and living related liver transplantation. [mazecordblood.com]

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Hypermenorrhea

Moderate to severe anemia can also cause shortness of breath, rapid heart rate, lightheadedness and headaches. Severe pain. [pharmacypedia.org]

[…] enough to cause increased anemia and is sometimes sufficient to be life threatening. [popline.org]

Most cases of anemia are mild, but even mild anemia can cause weakness and fatigue. [pharmacypedia.org]

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Leukemia

People may need blood transfusions if leukemia has caused severe anemia. They may need antibiotics if infections develop. [merckmanuals.com]

Severe in 90% Severe in 90% Mild in about 50% Mild in 80% Platelets Low in 80% Low in 90% Low in 20 to 30% High in 60% Low in 10% Lymphadenopathy Common Occasional Common [msdmanuals.com]

[…] in myeloblasts Occasionally hemolytic anemia and hypogammaglobulinemia Low leukocyte alkaline phosphatase level Philadelphia chromosome–positive in 90% Chronic leukemias [msdmanuals.com]

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Cooley's Anemia

Definitions Coo·ley's anemia a form of thalassemia characterized by severe anemia, growth retardation, etc. and usually resulting in death at an early age: the genes causing [yourdictionary.com]

There are both mild and severe forms of alpha thalassemia and beta thalassemia. Severe beta thalassemia is often called Cooley's anemia. [blood.emedtv.com]

Retrieved April 10th, 2019, from Cooley's anemia noun A usually fatal form of thalassemia in which normal hemoglobin is absent, characterized by severe anemia, enlargement [yourdictionary.com]

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Paroxysmal Nocturnal Hemoglobinuria

Some of the prominent symptoms of PNH include severe anemia, a condition resulting from having too few healthy red blood cells, severe abdominal pain, severe headaches, back [rapharma.com]

anemia) and other symptoms such as kidney failure, high blood pressure in the lungs, abdominal pain, shortness of breath, blood in your urine, problems swallowing, erectile [youtube.com]

This may result in severe anemia, agranulocytic angina, or both. Purpura is rare in PNH. 7. Chronic leukopenia in PNH is believed to be due to a leukocytic abnormality. [ashpublications.org]

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Chronic Lymphocytic Leukemia

Approximately 5-10% of CLL is complicated by autoimmune cytopenia (AIC), such as autoimmune hemolytic anemia (AIHA). [ncbi.nlm.nih.gov]

The most common adverse events were hematologic toxicities occurring in 61 patients (52.1%): severe neutropenia, thrombocytopenia, and anemia were observed in 23 (19.7%), [oadoi.org]

Several cases of AIC have reportedly demonstrated improvement during IBR treatment. However, in our case, the patient developed AIHA during oral IBR treatment. [ncbi.nlm.nih.gov]

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Acute Myeloid Leukemia

anemia characteristic of HP failure, an expected feature of AML • Polychromasia: reduced, since anemia is result of bone marrow production failure • Other RBC pathology: [slideshare.net]

severe anemia, neutropenic sepsis, and severe hemorrhage), providing further rationale for molecular evaluation of at-risk relatives. [ncbi.nlm.nih.gov]

Vitamin B12 deficiency May have a family history consistent with pernicious anemia. Paresthesia is an early symptom. [online.epocrates.com]

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Microcytic Anemia

Further evaluations indicate severe hypochromic microcytic anemia with decreased serum levels of iron, TIBC, and increased serum level of ferritin in this patient. [ncbi.nlm.nih.gov]

The clinical presentation of anemia varies according to its severity. [ncbi.nlm.nih.gov]

Both mk mice and Belgrade rats, which carry an identical DMT1 mutation, exhibit severe microcytic anemia at birth and defective intestinal iron use and erythroid iron use. [ncbi.nlm.nih.gov]

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Hereditary Spherocytosis

In immunocompromised individuals, chronic infections can occur and cause a severe, persistent anemia. [ncbi.nlm.nih.gov]

Individuals with the moderate/severe form have all the features of the moderate form but also have severe anemia. [ghr.nlm.nih.gov]

Patients presenting with the moderate / severe manifestation possess the same features of the moderate form but also have severe anemia. [visualdx.com]

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Malaria

anemia, thrombocytopenia, and bleeding complications. [ncbi.nlm.nih.gov]

The animal presented with thrombocytopenia, severe anemia, and hyperparasitemia during the acute infection. [ncbi.nlm.nih.gov]

Its diverse causes include respiratory compensation of metabolic acidosis, noncardiogenic pulmonary edema, concomitant pneumonia, and severe anemia. [ncbi.nlm.nih.gov]

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Congenital Dyserythropoietic Anemia

anemia resulting in cardiac failure and relatively mild dyserythropoietic features on bone marrow aspiration in contrast to severity of anemia. [ncbi.nlm.nih.gov]

Congenital dyserythropoietic anemia should be considered in the differential diagnosis of hydrops fetalis presenting with a very severe anemia and a skeletal abnormality of [ncbi.nlm.nih.gov]

We report the case of a male infant with a variant of congenital dyserythropoietic anemia (CDA), who developed severe hyperbilirubinemia on the day of birth, subsequent severe [ncbi.nlm.nih.gov]

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Precursor-Cell Lymphoblastic Leukemia

Laboratory findings revealed severe hypercalcemia, anemia, and renal insufficiency with decreased serum parathyroid hormone. [ncbi.nlm.nih.gov]

CASE REPORT We report the case of a 58-year-old male patient who presented with severe chest pain, dyspnea, systemic symptoms, leukopenia, normocytic anemia, and severe lactic [ncbi.nlm.nih.gov]

Severe in 90% Severe in 90% Mild in about 50% Mild in 80% Platelets Low in 80% Low in 90% Low in 20 to 30% High in 60% Low in 10% Lymphadenopathy Common Occasional Common [merckmanuals.com]

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Acute Leukemia

Further complicating matters, many patients with undiagnosed acute leukemia will first present with life-threatening complications, including febrile neutropenia, severe anemia [bcmj.org]

fatigue, severe bleeding (hemorrhage), fever (pyrexia), nausea, headache, low levels of white blood cells with fever (febrile neutropenia), liver damage (transaminases [fda.gov]

The clinical picture is marked by the effects of anemia, which is usually severe (fatigue, malaise), an absence of functioning granulocytes (proneness to infection and inflammation [meds.com]

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Glycogen Storage Disease Type 1

anemia in the absence of renal function compromise in children with glycogen-storage disease I has remained unclear. [emedicine.medscape.com]

For those with more severe hemolytic anemia, splenectomy has been utilized successfully, although the red blood cell defect persists, but the anemia is better compensated. [cancertherapyadvisor.com]

One report mentioned prolonged bleeding time and bruises after several years. 7 Patients had transplantation associated complications, including anemia in the first days after [ojrd.biomedcentral.com]

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Thalassemia

People who have thalassemias can have mild or severe anemia (uh-NEE-me-uh). [web.archive.org]

Thalassemia major (Cooley anemia) is characterized by severe anemia, enlargement of the spleen, and body deformities associated with expansion of the bone marrow. [britannica.com]

Severe Anemia and Other Signs and Symptoms People who have hemoglobin H disease or beta thalassemia major (also called Cooley's anemia) have severe thalassemia. [web.archive.org]

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Anemia of Infection

People with severe anemia may have more severe symptoms that may be life-threatening. [news-medical.net]

This process lowers the amount of red blood cells and can in a severe stage cause severe anemia. Malaria, how is it treated? [hemocue.com]

which may cause more severe anemia. [medbroadcast.com]

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Thalassaemia-Haemoglobin C Disease

[…] incompatible with life -severe anemia -mild anemia -no anemia Which of the following can help distinguish the combination Hgb S-b 0-thalassemia from sickle cell anemia? [quizlet.com]

It is more severe and commonly resembles the symptoms of sickle cell anemia (SS). [hinapatelfoundation.org]

Individuals with Sickle Hemoglobin-D disease (SD) have moderately severe anemia and occasional pain episodes. [scancainc.org]

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Blue Rubber Bleb Nevus Syndrome

Unexpectedly, chronic severe anemia due to systemic inflammation was diagnosed in an old anticoagulated patient with BRNBS. [ncbi.nlm.nih.gov]

He had severe anemia and venous swellings on the trunk. Similar lesions were found in the stomach, bowel and on his foot. [ncbi.nlm.nih.gov]

anemia. [ncbi.nlm.nih.gov]

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Beta Thalassemia

Individuals with thalassemia major usually present within the first two years of life with severe anemia, requiring regular red blood cell (RBC) transfusions. [ncbi.nlm.nih.gov]

Thalassemia can cause mild or severe anemia. Anemia occurs when your body does not have enough red blood cells or hemoglobin. [uchealth.org]

There are several types of this disorder: Beta thalassemia major (Cooley’s anemia). There are two damaged genes. This is the most severe form of this disorder. [hopkinsmedicine.org]

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Vitamin B12 Deficiency

anemia, such as angor, dyspnea on exertion, fatigue or symptoms related to congestive heart failure, such as ankle edema, orthopnea and nocturia. [ncbi.nlm.nih.gov]

The case also highlights the need to consider vitamin B12 deficiency in infants with severe anemia even if their hematological parameters do not indicate megaloblastic anemia [ncbi.nlm.nih.gov]

This also underlines the need to determine vitamin B12 and iron levels in all cases of otherwise unexplained severe anemia occurring in the first months of life. [doi.org]

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Immune Hemolytic Anemia

Eight of these cases of severe immune hemolytic anemia are described. [ncbi.nlm.nih.gov]

In the course of administration of an immunopotentiator, streptococcal agent OK-432, a patient with lung cancer was found to have severe anemia and a strongly positive antiglobulin [ncbi.nlm.nih.gov]

Upon hospital admission a patient was found to have severe anemia and a strongly positive direct antiglobulin test (DAT). [ncbi.nlm.nih.gov]

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Acquired Hemolytic Anemia

Blood transfusion if severe anemia. Warm antibody in IHA is a Panagglutinin. [slideshare.net]

severe anemia) and also of severe treatment-induced infections. [orpha.net]

[…] enzyme deficiency and chronic hemolytic anema, Class II: severe enzyme deficiency but intermittent hemolytic anemia, Class III: moderate enzyme deficiency with intermittent [memorize.com]

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Autoimmune Hemolytic Anemia

When autoimmune hemolytic anemia is secondary to a paraneoplastic process, severe anemia can occur leading to significant morbidity and even mortality. [ncbi.nlm.nih.gov]

Mixed warm and cold autoimmune hemolytic anemia runs a chronic course with severe intermittent exacerbations. [ncbi.nlm.nih.gov]

Because of his severe anemia, on admission to the hospital he was found to have altered mental status, metabolic acidosis, abnormal liver function tests, and a severe coagulopathy [ncbi.nlm.nih.gov]

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Fetal Erythroblastosis

Severe late anemia of hemolytic disease of new born. Pediatric Child Health. 1999;4(3):201-3. [doi.org]

Both infants presented with severe symptomatic anemia ( Table 1 ). [doi.org]

anemia, leading to neurological sequelae in one case. [ncbi.nlm.nih.gov]

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