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34 Possible Causes for Severe Developmental Delay in Survivors

  • Acidosis

    Patients known as "survivors", i.e. those who have survived several episodes, cross a critical threshold and show less severe symptoms including hypotonia, asthenia, developmental[orpha.net] delay (language acquisition and walking) and, in older patients, truncal ataxia, and a characteristic wide-based gait.[orpha.net]

  • Diaphragmatic Hernia

    Perinatal mortality is increased with Cornelia de Lange syndrome; survivors are developmentally delayed 6,7,8. Table I.[iame.com] Cornelia de Lange Syndrome This syndrome can be suspected when a congenital diaphragmatic hernia is associated with several of the additional stigmata outlined in Table I.[iame.com]

  • Meningitis

    […] sequelae, including developmental delay, hydrocephalus, sensorineural deafness and seizures.5–8 The clinical severity of meningitis depends on both the nature of the infecting[dx.doi.org] The fatality rates in industrialized countries are between 5% and 10%, and are considerably higher in the developing world.1–6 Survivors often have resulting neurological[dx.doi.org]

  • Patau Syndrome

    Survivors with Patau syndrome exhibit severe mental retardation and developmental delays and are at increased risk for malignancy.[emedicine.com]

  • Hydrophthalmos

    Survivors exhibit severe developmental delay. Case report The neonate we describe was a female born prematurely by caesarean section at 28 weeks gestational age.[nature.com]

  • Opsoclonus-Myoclonus Syndrome

    In contrast, seven children continued to have a severe developmental delay at T2.[ncbi.nlm.nih.gov] No significant difference in any of the variables was found between NBL survivors and OMS patients without NBL.[ncbi.nlm.nih.gov]

  • Organic Aciduria

    severe developmental delay and recurrent hyperammonemic crises[ 4 – 7 ].[doi.org] Clinical features are typical in complete deficiencies, which present with hyperammonemic coma a few days after birth with 50% mortality[ 4 – 7 ], whereas the survivors experience[doi.org]

  • Lactic Acidosis

    Patients known as "survivors", i.e. those who have survived several episodes, cross a critical threshold and show less severe symptoms including hypotonia, asthenia, developmental[orpha.net] delay (language acquisition and walking) and, in older patients, truncal ataxia, and a characteristic wide-based gait.[orpha.net]

  • Chronic Respiratory Acidosis

    Patients known as "survivors", i.e. those who have survived several episodes, cross a critical threshold and show less severe symptoms including hypotonia, asthenia, developmental[orpha.net] delay (language acquisition and walking) and, in older patients, truncal ataxia, and a characteristic wide-based gait.[orpha.net]

  • Trisomy 18

    Abstract Trisomy 18 is a common chromosomal aberration syndrome involving growth impairment, various malformations, poor prognosis, and severe developmental delay in survivors[ncbi.nlm.nih.gov]

Further symptoms