Severe Disorder: Causes & Reasons

Possible Causes for Severe Disorder

Muscular Dystrophy-Dystroglycanopathy Type A1

Fukuyama congenital muscular dystrophy is a more severe disorder characterized by brain malformations, hypotonia and muscle weakness. [sema4.com]

[…] anomaly disorders known as the cobblestone lissencephalies. [read.qxmd.com]

[…] characterized by severe congenital muscular dystrophy, structural brain anomalies and eye abnormalities. [oxfordmedicine.com]

Muscular Dystrophy-Dystroglycanopathy Type A3

Brain histology shows severely disorganized cytoarchitecture and suggests a neuronal migration disorder. Microtia has been reported in several patients. [disorders.eyes.arizona.edu]

[…] neuronal migration disorder Walker-Warburg syndrome. [genome.jp]

Other disorders that should be excluded are Meckel syndrome, Fryns syndrome, trisomies 18 and 13, severe Fukuyama-type congenital muscular dystrophy (FCMD) (1) and maternal [thefetus.net]

Muscular Dystrophy-Dystroglycanopathy Type A2

The disorder represents the most severe end of a phenotypic spectrum of similar disorders resulting from defective glycosylation of alpha-dystroglycan (DAG1; 128239), collectively [ncbi.nlm.nih.gov]

Brain histology shows severely disorganized cytoarchitecture and suggests a neuronal migration disorder. Microtia has been reported in several patients. [disorders.eyes.arizona.edu]

Severe Malignant Osteopetrosis November 20, 2018 by Peter Ciszewski Osteopetrosis refers to a group of rare, inherited skeletal disorders characterized by increased bone density [checkrare.com]

Fatal Infantile Lactic Acidosis with Methylmalonic Aciduria

Clinically it manifests with severe psychomotor delay, hypotonia, failure to thrive, feeding difficulties and dystonia. [orpha.net]

ORPHA:17 Classification level: Disorder Synonym(s): - Prevalence: Unknown Inheritance: Autosomal recessive Age of onset: Infancy, Neonatal ICD-10: E71.1 OMIM: 245400 UMLS: [orpha.net]

Charcot-Marie-Tooth Disease Type 4H

Depending on the specific gene that is altered, this severe, early-onset form of the disorder may also be classified as CMT1 or CMT4. [medlineplus.gov]

Clinically and pathologically very similar to Charcot-Marie-Tooth type 4B1 with childhood-onset of muscle weakness, senso / 715800000 SNOMEDCT-BE (disorder) / 715800000 A [wordscope.com]

Clinically and pathologically very similar to Charcot-Marie-Tooth type 4B1 with childhood-onset of muscle weakness, senso / 715800000 SNOMEDCT-BE (disorder) / 715800000 Autosomal [wordscope.com]

Amish Lethal Microcephaly

A new metabolic disorder characterized by severe congenital microcephaly, death within the first year, and severe 2-ketoglutaric aciduria has been found among the Old-Order [jhu.pure.elsevier.com]

@article{Kelley2002AmishLM, title={Amish lethal microcephaly: a new metabolic disorder with severe congenital microcephaly and 2-ketoglutaric aciduria.}, author={Richard I [semanticscholar.org]

PY - 2002/11/1 Y1 - 2002/11/1 N2 - A new metabolic disorder characterized by severe congenital microcephaly, death within the first year, and severe 2-ketoglutaric aciduria [jhu.pure.elsevier.com]

Mixed Anxiety and Depressive Disorder

disorder, With mild use disorder F10.259Alcohol-induced psychotic disorder, With moderate or severe use disorder F10.959Alcohol-induced psychotic disorder, Without use disorder [dr-bob.org]

severity of the disorder,” the authors reported. [psychiatryadvisor.com]

The scale measures the severity of the disorder (CGI-S) and also improvement during the therapy (CGI-I). [dovepress.com]

Bipolar Disorder

These findings may lead to new therapeutic strategies influencing epigenetic targets in severe psychiatric disorders. [ncbi.nlm.nih.gov]

Bipolar disorder, severe, with psychosis Bipolar disorder, severe, without psychosis Bipolar disorder, severe, wo psychosis Mild bipolar disorder Moderate bipolar disorder [icd9data.com]

[…] models of severe psychiatric disorders. [ncbi.nlm.nih.gov]

Somatic Delusional Disorder

Several new chapters dealing with new concepts in biology and treatment of mental disorders have been added. [books.google.com]

A case of somatic delusional disorder with a severe secondary eating disorder is described. [ncbi.nlm.nih.gov]

disorders. [books.google.com]

Adjustment Disorder

ICD-10) severe stress and adjustment disorder diagnoses between 1995 and 2011. [ncbi.nlm.nih.gov]

The aim of this study was to determine the prevalence of adjustment disorder in the first 12 months after severe injury; to determine whether adjustment disorder was a less [ncbi.nlm.nih.gov]

Cyclothymic Disorder

disorder but of a less severe nature. [icd10data.com]

Cyclothymic disorder, or cyclothymia, is a mood disorder that causes periods of highs and lows. It is a less severe type of bipolar disorder. [sharecare.com]

recurrent, moderate F33.2 Major depressive disorder, recurrent severe without psychotic features F33.3 Major depressive disorder, recurrent, severe with psychotic symptoms [icd10data.com]

Somatoform Disorder

Functional disability is a critical measure of treatment outcome in children with severe somatoform disorder. [academic.oup.com]

Disturbi somatoformi gravi e persistenti: diagnosi e trattamento [translation of “Severe and enduring somatoform disorders: recognition and management” by Serena Saraceni [cambridge.org]

Feldman, E. ( 2000 ) Delivering services for severe somatoform disorders. In Severe Mental Illness (ed. Gregoire, A. ), pp. 282 – 293. Oxford : Greenwich Press. [bjp.rcpsych.org]

Dissociative Disorder

Some symptoms can be similar for several disorders. [mindjersey.org]

Chronic child abuse often associated with severe DDs, like dissociative identity disorder, is likely to heighten shame and relationship concerns. [ncbi.nlm.nih.gov]

This study provides further evidence of the association of severe dissociative disorders with trauma, particularly child abuse. [ncbi.nlm.nih.gov]

Severe Combined Immunodeficiency

Severe combined immunodeficiency disorders represent pediatric emergencies due to absence of adaptive immune responses to infections. [ncbi.nlm.nih.gov]

The study aims to identify variables contributing to the best outcomes for stem cell transplant as treatment for severe combined immunodeficiency disorder. [mayo.edu]

Infants with selected CD8 deficiency and severe autoimmune disorders or exaggerated inflammation should be screened for ZAP70 deficiency. [ncbi.nlm.nih.gov]

Dysthymic Disorder

Some researchers suggest that the majority of these individuals are never diagnosed or are not diagnosed until a more severe episodic mood disorder develops. [ncbi.nlm.nih.gov]

Depression escitalopram Dysthymic disorder is a mood disorder consisting of chronic depression, with less severe but longer lasting symptoms than major depressive disorder [shockmd.com]

Dysthymic Disorder A less severe type of depression, dysthymic disorder is experienced long-term and includes chronic symptoms which prevent optimal functioning and deteriorate [traumasurvivorsnetwork.org]

Panic Disorder

How to Fight Severe Panic Disorder Severe panic disorder requires a complete and intensive treatment. [calmclinic.com]

Results of regression analyses showed alexithymia as a mediator between the different types of CT and panic disorder severity, except sexual abuse. [ncbi.nlm.nih.gov]

In general, severity of panic disorder plays only a moderate role in treatment, since the treatments for panic disorder tend to be similar regardless of severity. [calmclinic.com]

Organic Personality Disorder

Anxiety (Definition) Anxiety is a general term for several disorders that cause nervousness, fear, apprehension, and worrying. [healthtap.com]

[…] alcoholism in hospitalized patients with severe personality disorders. [en.wikibooks.org]

Results Thirty-nine per cent of the sample met the criteria for severe personality disorder. [bjp.rcpsych.org]

Mood Disorder

Adults who have severe and ongoing mental illness — schizophrenia, schizoaffective disorder, other psychotic illnesses, severe mood disorders, or personality disorders — benefit [upmc.com]

For more information about our Mood Disorders Treatment and Research programs, or to make a referral, call 1-888-427-1532. [upmc.com]

Diamond Brain Imaging Study Are you a young adult who is currently feeling severely distressed, or are you a young adult who is feeling happy, content, satisfied and has never [upmc.com]

Acute Anxiety

These disorders may be severe and interfere with the ability to live a functional, productive life. [livestrong.com]

See also Post-traumatic Stress Disorder. Treatment The disorder may resolve itself with time or may develop into a more severe disorder such as PTSD. [allpsych.com]

Perhaps the anxiety disorder best known for severe effects is panic disorder. [healthyplace.com]

Inherited Platelet Disorder

The most rare and severe platelet disorders are Bernard-Soulier syndrome (BSS) and Glanzmann Thrombasthenia: Bernard-Soulier syndrome - It is a severe inherited bleeding disorder [wrbd.org]

The most common bleeding disorder is von Willebrand disease (VWD). It is generally less severe than other bleeding disorders. [haemophilia-kenya.org]

Prognosis The outcome depends on the specific disorder and the severity of its symptoms. [medical-dictionary.thefreedictionary.com]

Adjustment Reaction of Adolescence

disorder, current episode depressed, severe, without psychotic features F315Bipolar disorder, current episode depressed, severe, with psychotic features F3160Bipolar disorder [cms.gov]

Adjustment disorders are often diagnosed when it's not clear the person meets the criteria for a more severe disorder, or the actual diagnosis is uncertain. [hopecounselingservices.net]

Critics also pointed to the danger of using this diagnosis in adolescence rather than noting more severe psychopathology such as schizophrenia or personality disorders. [slideshare.net]

Neurotic Disorder

Access to psychiatric treatment by people with neurotic disorders in the general population is likely to be affected both by the severity of disorder and by sociodemographic [tandfonline.com]

BACKGROUND: Access to psychiatric treatment by people with neurotic disorders in the general population is likely to be affected both by the severity of disorder and by sociodemographic [ncbi.nlm.nih.gov]

There are also inequalities in the receipt of treatment, although the major influence is the severity of disorder. [tandfonline.com]

Alcoholic Amnestic Disorder

Alcohol use disorder, severe, with alcohol-induced bipolar or related disorder Alcohol use disorder, severe, with alcohol-induced depressive disorder F10.25 Alcohol dependence [icd10coded.com]

There are various causes of Amnestic Disorders, which range from severe trauma to brain disorders such as Alzheimer’s disease, stroke, encephalitis, and seizures. [allaboutcounseling.com]

moderate, WITH alcohol-induced major neurocognitive disorder, amnestic-confabulatory type Alcohol use disorder, severe, WITH alcohol-induced major neurocognitive disorder [icdlist.com]

Kostmann Syndrome

Kostmann syndrome is a rare, severe, congenital neutropenia disorder characterized by a lack of mature neutrophils (absolute neutrophil counts less than 500 cells/mm3) associated [ebi.ac.uk]

Homepage Rare diseases Search Search for a rare disease Disease definition Kostmann syndrome is a rare, severe, congenital neutropenia disorder characterized by a lack of [orpha.net]

Severe congenital neutropenia-3 is an autosomal recessive bone marrow failure disorder characterized by low numbers of neutrophils, increased susceptibility to bacterial and [ncbi.nlm.nih.gov]

Tic Disorder

BACKGROUND: Clinical experience suggests an association between stressful life events and fluctuations in symptom severity of tic disorder patients. [ncbi.nlm.nih.gov]

Abstract Tourette's syndrome, no longer considered as a rare and unusual disease, is the most severe tic disorder in children. [ncbi.nlm.nih.gov]

Tourette syndrome, the most severe kind of tic disorder, involves both motor and vocal tics that go on for at least a year. [kidshealth.org]

Achondrogenesis Type 1B

Get Update Overview Achondrogenesis is a group of severe disorders that are present from birth and affect the development of cartilage and bone. [diseaseinfosearch.org]

A terrible disease that the Golgi Body causes is Achondrogenesis which is a group of severe disorders that affect cartilage and bone development. [organelleproblems.weebly.com]

The severity of mutation determines which disorder the patient will have. The most severe of these disorders is type 1B. [encyclopedia.com]

Achondrogenesis Type 2

Achondrogenesis, type 2 is a severe, inherited disorder of bone growth. [goldbamboo.com]

Get Update Overview Achondrogenesis is a group of severe disorders that are present from birth and affect the development of cartilage and bone. [diseaseinfosearch.org]

The severity of mutation determines which disorder the patient will have. The most severe of these disorders is type 1B. [encyclopedia.com]

Atelosteogenesis Type 2

Atelosteogenesis, type II is a severe disorder of cartilage and bone development. [goldbamboo.com]

Genetics Home Reference Atelosteogenesis type 2 is a severe disorder of cartilage and bone development. [rarediseases.oscar.ncsu.edu]

Description Atelosteogenesis type 2 is a severe disorder of cartilage and bone development. [medlineplus.gov]

Amphetamine Delusional Disorder

disorder) Psychostimulant dependence (severe use disorder) Psychostimulant dependence, episodic Psychostimulant dependence, moderate use Psychostimulant dependence, severe [icd10data.com]

Moderate 296.34 Major Depressive Disorder, Recurrent, Severe With Psychotic Features 296.33 Major Depressive Disorder, Recurrent, Severe Without Psychotic Features 296.3 [dr-bob.org]

single manic episode, severe without psychotic features 296.04 Bipolar I disorder, single manic episode, severe with psychotic features 296.05 Bipolar I disorder, single [nidagenetics.org]

Factitious Disorder

What causes factitious disorder imposed on self is unknown, but stress and a severe personality disorder, most often borderline personality disorder, may be involved. [merckmanuals.com]

The cause is unknown, although stress and a severe personality disorder, most often borderline personality disorder, are often implicated. Diagnosis is clinical. [merckmanuals.com]

The cause is unknown, but stress and a severe personality disorder may contribute. Symptoms may be dramatic and convincing. [merckmanuals.com]