Severe Hypotension: Causes & Reasons

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Possible Causes for Severe Hypotension

Orthostatic Hypotension

A 71-year-old man, who was diagnosed with familial amyloidosis type I, was admitted for treatment of severe orthostatic hypotension associated with recurrent syncopal attacks [ncbi.nlm.nih.gov]

Here we consider the evidence for midodrine in the treatment of severe orthostatic hypotension and how it fits with current management strategies. [ncbi.nlm.nih.gov]

She had severe orthostatic hypotension (supine systolic blood pressure 186 mmHg and standing 79 mmHg). [ncbi.nlm.nih.gov]

Orthostatic Intolerance due to NET Deficiency

A cup of coffee or tea with each meal tends to reduce the severity of orthostatic hypotension. [betterhealth.vic.gov.au]

Urinary salt and water loss cause severe dehydration, plasma hypertonicity, acidosis, decreased circulatory volume, hypotension, and, eventually, circulatory collapse. [merckmanuals.com]

Severe orthostatic hypotension following weight reduction surgery. Arch Intern Med. 2001;161:2145–2147. 11. Billakanty S, Klingman M, Kanjwal Y, Kosinski D, et al. [bariatrictimes.com]

Bolivian Hemorrhagic Fever

The disease in infected animals was also characterized by the development of hypotension and coagulation abnormalities as indicated by severe thrombocytopenia and prolongation [ajtmh.org]

Hypotension may also have been due to decreased plasma protein synthesis. [ajtmh.org]

[…] likely causes of the hemorrhagic tendencies of this disease in infected monkeys were thrombocytopenia and decreased synthesis of coagulation and other plasma proteins due to severe [ajtmh.org]

Argentinian Hemorrhagic Fever

shock, severe myalgia, leukopenia, thrombocytopenia, transient hypocomplementemia Management Rehydration; high–15-45% mortality may ↓ to 1-4% with convalescent serum- specific [medical-dictionary.thefreedictionary.com]

Body systems harmed by Argentine hemorrhagic fever Severe cases of AHF may progress to: Shock Pulmonary edema Diffuse mucosal hemorrhaging Meningoencephalitis with convulsions [naturalpedia.com]

Rodent vectors Akodon arenicola, Calomys laucha, C musculinus Clinical 1-2 wk incubation, followed by mucocutaneous hemorrhage, fever, anorexia, N&V, fluid loss and oliguria, hypotension [medical-dictionary.thefreedictionary.com]

Lassa Fever

Haemorrhage Hypotension Pleural Effusion Seizures Swelling of Face and Neck Approximately 15% of hospitalized patients die. [whereincity.com]

Visceral hemorrhage, respiratory distress, facial edema and hypotension is frequently encountered. [symptoma.com]

Severe cases result in hypotension, pleural effusion, hemorrhage, seizures, encephalopathy, and swelling of the face and neck. [bio.davidson.edu]

Venezuelan Hemorrhagic Fever

Viral hemorrhagic fevers (VHFs) are a group of febrile illnesses caused by RNA viruses from several viral families. [emedicine.medscape.com]

[…] highly infectious viruses lead to a potentially lethal disease syndrome characterized by fever, malaise, vomiting, mucosal and gastrointestinal (GI) bleeding, edema, and hypotension [emedicine.medscape.com]

Hypotension

This case report is the first to demonstrate severe intraoperative hypotension and urticaria from dermographism. [ncbi.nlm.nih.gov]

Initially, she had severe systemic hypotension (41/17 mm Hg). [ncbi.nlm.nih.gov]

When severe hypotension occurs, it prevents oxygen from getting to the brain and other organs, leading to serious problems or can even be fatal. [childrens.com]

Capillary Leak Syndrome

Adult subjects with systemic capillary leak syndrome (SCLS) present with acute and recurrent episodes of vascular leak manifesting as severe hypotension, hypoalbuminemia, [ncbi.nlm.nih.gov]

Idiopathic systemic capillary leak syndrome (SCLS) is a rare process characterized by acute and recurrent episodes of vascular leakage with severe hypotension, hypoalbuminemia [ncbi.nlm.nih.gov]

It is characterized by recurrent episodes of generalized edema and severe hypotension along with hypoproteinemia. [ncbi.nlm.nih.gov]

Dopamine Beta-Hydroxylase Deficiency

Patients with dopamine beta-hydroxylase deficiency have generally been detected in adolescence or adulthood following the onset of severe orthostatic hypotension. [medlink.com]

The mode of inheritance is autosomal recessive, and several different mutations have been identified (Garland et al 2002; Deinum et al 2004). [medlink.com]

DbetaH deficiency is mainly characterized by cardiovascular disorders and severe orthostatic hypotension. [ncbi.nlm.nih.gov]

Bilateral Massive Adrenal Hemorrhage

At admission, the man presented with fever, severe hypotension, hyperazotemia, acidosis, normonatremia and hypocoagulability, while the girl with severe hypotension, fever [ncbi.nlm.nih.gov]

Invasive monitoring may demonstrate severe hypotension ( 4 L/min/m2), low systemic vascular resistance ( FIGURE 72-1. [mitchmedical.us]

During the postoperative period, the patient presented abdominal pain, nausea, fever, hypotension and severe respiratory distress. [elsevier.es]

Shy-Drager Syndrome

The initial hypertension in the supine position followed by severe hypotension after hydralazine administration, ultimately responsive to vasopressin, led to a diagnosis of [ncbi.nlm.nih.gov]

The use of vasopressin for severe hypotension in patients with autonomic dysfunction unresponsive to vasopressors should be considered. References 1. [journals.lww.com]

The initial hypertension was treated with a direct vasodilator (hydralazine) which resulted in severe hypotension unresponsive to adrenergic agonists. [journals.lww.com]

Kounis Syndrome

Five minutes after receiving a vial of intravenous metamizole, she started to show generalized urticaria, chest pain, and intense dyspnea, accompanied by severe hypotension [revespcardiol.org]

Physical examination demonstrated a heart rate of 30 bpm and severe hypotension (60/40 mmHg). [signavitae.com]

Acetaminophen (Tylenol® or paracetamol), especially its intravenous administration, is not recommended because it might cause severe hypotension due to reduction of cardiac [tmsforacure.org]

Beta Blocker Poisoning

[…] preventing insulin release, so can see hyperglycemia as opposed to the normal-low sugar in B-Blockers Presentation Weak/Dizzy, mild confusion, bradycardia progressing to severe [emcrit.org]

In severe poisoning hypotension can occur from bradyarrhythmia as well as direct myocardial depression. [emergpa.net]

The increase in cAMP can also cause vasodilation, however, which can worsen hypotension. [sinaiem.org]

Pure Autonomic Failure

In the patient, ambulatory blood pressure recording revealed severe hypotension (50/30 mm Hg) after a stressful event. [ncbi.nlm.nih.gov]

All patients had severe symptomatic postural hypotension, without neurological deficits. [ncbi.nlm.nih.gov]

He had severe orthostatic hypotension, abnormal cardiovagal reflexes, and paradoxical sweating in the upper trunk at a room temperature of 18°C. [ncbi.nlm.nih.gov]

Amniotic Fluid Embolism

The plasma bradykinin-generating capacity was found to be very low at the time of the initial clinical manifestations, which were characterized by severe hypotension, cardiorespiratory [ncbi.nlm.nih.gov]

The diagnosis of AFE was made by symptoms of dyspnea, coagulopathy, and severe hypotension. ZnCP-1, the characteristic component of meconium, was elevated in the serum. [ncbi.nlm.nih.gov]

Its main clinical features are severe hypotension, arrhythmia, cardiac arrest, pulmonary and neurological manifestations, and profuse bleeding because of disseminated intravascular [ncbi.nlm.nih.gov]

Phenothiazine Poisoning

If severe hypotension should occur, supportive measures including the use of intravenous vasopressor drugs should be instituted immediately. [home.intekom.com]

Diagnosis Patients presenting with ventricular dysrhythmias, wide QRS complexes, or severe hypotension should be suspected of poisoning by a sodium channel antagonist. [calpoison.org]

Tolerance to the hypotensive effects often develops after a few doses. Rarely, fatal cardiac arrest has occurred secondary to severe hypotension. [drugs.com]

Sheehan Syndrome

It is usually the result of severe hypotension or shock caused by massive hemorrhage during or after delivery. [ncbi.nlm.nih.gov]

Necrosis may occur as a result of severe hypotension or shock due to excessive uterine bleeding following childbirth. [en.wikipedia.org]

During delivery, she sustained a fourth-degree perineal laceration with severe bleeding and hypotension (blood pressure, 60/30 mm Hg). [ajnr.org]

Acute Massive Pulmonary Embolism

Six hours postoperatively, she required emergent intubation when she suddenly became cyanotic, severely hypotensive, and tachypneic, with an oxygen saturation of 50%. [ncbi.nlm.nih.gov]

In the setting of severe hypotension, the finding of RV dysfunction is enough to prompt rapid reperfusion. [emdocs.net]

For the first episode, the patient suffered severe hypotension and no pulsation, a situation similar to PEA. [ispub.com]

Micturition Syncope

To describe a case of severe hypotension and occasional syncope following intermittent catheterisations in a tetraplegic patient. [ncbi.nlm.nih.gov]

Objective: To describe a case of severe hypotension and occasional syncope following intermittent catheterisations in a tetraplegic patient. [nature.com]

A 47-year-old man presenting with C7 ASIA B tetraplegia for 9 months, developed episodes of severe hypotension and occasional syncope following intermittent catheterisations [ncbi.nlm.nih.gov]

Tricyclic Antidepressant Overdose

Cardiovascular toxicity accounts for the majority of the fatalities and may include a hyperdynamic response, various arrhythmias and heart blocks, or severe hypotension. [ncbi.nlm.nih.gov]

These results suggest that hypotension is common after severe TCA overdose and occurs independently of TCA level and prolongation of the QRS interval. [ncbi.nlm.nih.gov]

Seven patients (23%) had admission hypotension, 7 (23%) had severe respiratory depression, 6 (20%) had seizures and 4 (13%) had cardiac arrhythmias. One patient died. [ncbi.nlm.nih.gov]

Addisonian Crisis

Classically it presents as severe hypotension refractory to IV fluids and vasopressors. [coreem.net]

hypotension leading to shock. [icdlist.com]

A 22-year-old man was admitted to an intensive care unit with severe hyponatremia, hypotension and somnolence. [ncbi.nlm.nih.gov]

Phosphine Poisoning

The dominant clinical feature is severe hypotension refractory to dopamine therapy. Diagnosis depends on the clinical suspicion. [emnote.org]

Singh and colleagues [5] demonstrated that non-survivors had more severe hypotension and metabolic acidosis than survivors who had more severe vomiting at aluminium phosphide [journals.lww.com]

Nonsurvivors have more severe hypotension and metabolic acidosis than the survivors who have more severe vomiting [31]. [esim.eg.net]

Traumatic Pneumothorax

However, tension pneumothorax can cause severe hypotension, and open pneumothorax can compromise ventilation. [msdmanuals.com]

Sump Syndrome

A few hours after admission to the hospital, the patient developed severe hypotension, hypoxia, and confusion. He was immediately transferred to ICU and was intubated. [ncbi.nlm.nih.gov]

Assuming that a side-to-side CDD had been performed several decades before in the context of a revision of the CBD due to complicated cholecystectomy, an urgent ERCP was performed [ncbi.nlm.nih.gov]

Acute Pandysautonomia

Since then, several other cases have been described. 2-6 The characteristic features of this syndrome include severe orthostatic hypotension, impaired gastrointestinal and [n.neurology.org]

[…] of orthostatic hypotension decreased. [medlit.ru]

The patient showed "severe postural hypotension without change in heart rate, leading occasionally to fainting without change in heart rate, total absence of sweating, extreme [medlink.com]

Diffuse Intraventricular Block

hypotension with Lopressor"). [manual.jointcommission.org]

Alpha blockers can cause severe first dose hypotension potentially resulting in syncope, thus they are frequently given a night before bedtime. [healio.com]

There are five useful clinical signs to establish the presence and severity of cardiomyopathy: general appearance (cachexia and dyspnea at rest indicate severe impairment) [clevelandclinicmeded.com]

Phenobarbital Poisoning

We report the successful use of continuous renal replacement therapy in a case of severe phenobarbital poisoning associated with severe coma and hypotension. [ncbi.nlm.nih.gov]

In addition, coma recurred and hypotension developed during the procedure in the IHD group.[8] Different studies have also shown that CVVHDF is highly effective in severe [actamedicainternational.com]

[…] poisoning they may wshow paralytic dilation), oliguria, tachycardia, hypotension, lowered body temperature, and coma. [rxlist.com]

Orthostatic Syncope

Although symptom recurrence on follow-up was lower in patients with more severe orthostatic hypotension, the clinical significance of this finding needs to be further defined [ncbi.nlm.nih.gov]

The summary of product characteristics does not define severe orthostatic hypotension because assessment of severity is subjective, based on symptoms and the impact of the [nice.org.uk]

Chronic severe orthostatic hypotension may present as fluctuating cognition/ delirium. [en.wikipedia.org]

OxyContin

Severe Hypotension OxyContin may cause severe hypotension including orthostatic hypotension and syncope in ambulatory patients. [oxycontin.com]

hypotension including orthostatic hypotension and syncope in ambulatory patients; there is increased risk in patients whose ability to maintain blood pressure has already [reference.medscape.com]

[…] withdrawal symptoms; when discontinuing therapy in physically-dependent patient, gradually taper dosage; do not abruptly discontinue therapy in these patients Therapy may cause severe [reference.medscape.com]

Theophylline Poisoning

The low incidence of life-threatening manifestations of severe toxicity (hypotension, serious arrhythmias or seizures) and excellent outcome, contrasts with many previous [ncbi.nlm.nih.gov]

Potential life-threats are likely to be delayed by many hours: hypotension seizures supraventricular tachycardia Metabolic abnormalities potassium supplementation for severe [lifeinthefastlane.com]

Severe cases • N.B. [fr.slideshare.net]