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2,802 Possible Causes for Severe Mental Retardation

  • Mental Retardation

    mental retardation, infantile hypotonia, progressive neurologic impairment, recurrent infections, bladder dysfunction, and absent speech.[] Based on twin studies, moderate to severe mental retardation does not appear to be familial, but mild mental retardation does.[] […] functional disomy of chromosome Xq28, including MECP2 as the critical dosage-sensitive gene, are associated with a distinct clinical phenotype in males, characterized by severe[]

  • Profound Mental Retardation

    mental retardation.[] Only three cases have been reported in people with severe or profound mental retardation.[] Mental Retardation, Lewis, Pamela F.[]

  • Patau Syndrome

    Survivors suffer from severe mental retardation and health problems all their lives.[] mental retardation may complicate survival Please rate topic.[] Survivors with Patau syndrome exhibit severe mental retardation and developmental delays and are at increased risk for malignancy.[]

  • Acrocallosal Syndrome

    It is characterised by moderate to severe mental retardation, hypotonia, agenesis of the corpus callosum and preaxial polydactyly involving both feet and the facial features[] mental retardation.[] Typical characteristics of ACLS are hypoplasia/agenesis of corpus callosum, moderate to severe mental retardation, characteristic craniofacial abnormalities, distinctive digital[]

  • Mowat-Wilson Syndrome

    Mowat-Wilson syndrome is a genetic disorder characterized by a distinct facial appearance, moderate-to-severe mental retardation, microcephaly, agenesis of the corpus callosum[] Mowat-Wilson syndrome (MWS) is characterized by severe mental retardation with seizures, specific facial dysmorphism, Hirschsprung disease, anomalies of the corpus callosum[] Mowat-Wilson syndrome is a recently delineated severe mental retardation, multiple congenital anomalies syndrome caused by dominant nonsense or frameshift mutations, deletions[]

  • Chudley-Rozdilsky Syndrome

    Severe mental and growth retardation becomes apparent when the child fails to reach the corresponding developmental milestones.[] Characterized by a congenital, nonprogressive myopathy secondary to (proved histologically and electron microscopically) Multicore myopathy, severe mental retardation, radiologic[] Early and severe mental retardation Mental retardation, severe Severe mental retardation [ more ] 0010864 Myopia Close sighted Near sighted Near sightedness Nearsightedness[]

  • Coffin-Lowry Syndrome

    The degree of severity of the MRI findings correlated with the severity of mental retardation in the patients.[] It is manifested by moderate to severe mental retardation and characteristic facial, hand and skeletal malformations.[] The moderate phenotypic expression of this mutation extends the CLS phenotype to include less severe mental retardation and minor, hitherto unreported signs.[]

  • Pitt-Hopkins Syndrome

    Pitt-Hopkins syndrome (PHS) is a rare syndromic mental disorder, which is mainly characterized by severe motor and mental retardation including absent language development[] All of these proven patients were severely mentally retarded and showed a distinct facial gestalt.[] The presence of severe mental retardation associated with anomalous breathing pattern may suggest the Joubert and Rett syndrome, however these were excluded on the basis of[]

  • Warburg Micro Syndrome 3

    mental retardation, spastic diplegia, and hypogonadism.[] mental retardation, spastic diplegia, and hypogonadism (summary by Morris-Rosendahl et al., 2010).[] […] recessive syndrome characterized by microcephaly, microphthalmia, microcornea, congenital cataracts, optic atrophy, cortical dysplasia, in particular corpus callosum hypoplasia, severe[]

  • Vitamin B12 Deficiency

    Infantile vitamin B12 deficiency has to be considered in the differential diagnosis of mental retardation and infantile spasms, especially if maternal nutritional deficiency[] At the age of 8 years, the girl is symptom-free and visits primary school illustrating remarkable recovery of severe neurodevelopmental delay and symptomatic West syndrome[]

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