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254 Possible Causes for Severe Mental Retardation in Some Patients, Skin Plaque

Did you mean: Severe Mental Retardation, in Some Patients, Skin Plaque

  • Cryopyrin-Associated Periodic Syndrome

    Improvement of long-term complications have also been reported in some patients with hearing loss, loss of vision, amyloidosis (kidney disease), growth retardation, but not[] Skin biopsy revealed a sparse infiltrate throughout the entire dermis, including the eccrine adventitia.[] […] the bone abnormalities or existing mental retardation seen in severe NOMID/CINCA.[]

  • Ichthyosis

    The skin can be ichthyotic and severe mental retardation is often accompanied by seizures.[] The dead cells of this horny layer do not slough off at the normal rate but tend instead to adhere to the skin surface to form scales; horny plaques and papules may also be[] […] scaly patches and plaques Clinical images Images hosted on other servers: Lamellar ichthyosis Microscopic (histologic) description Increased stratum corneum with loss of[]

  • Pregnancy

    Discussion: severe mental retardation and cancer among atomic bomb survivors exposed in utero.[] Pruritic urticarial papules and plaques of pregnancy (PUPPP), a skin disease that develops around the 32nd week.[] Signs are red plaques, papules, and itchiness around the belly button that then spreads all over the body except for the inside of hands and face.[]

  • Alzheimer Disease

    MEF2C haploinsufficiency caused by either microdeletion of the 5q14.3 region or mutation is responsible for severe mental retardation with stereotypic movements, epilepsy[] Rosacea, a chronic inflammatory condition of the skin, is also associated with an increased risk of Alzheimer disease, particularly among individuals age 60 or older.[] Neuropathology Neuritic plaques and neurofibrillary tangles The presence of neuritic plaques and neurofibrillary tangles in the brain are used to diagnose Alzheimer disease[]

  • Confluent and Reticulated Papillomatosis

    He has been developmentally delayed since birth and severely mentally retarded, with no speech and little social response.[] Skin lesions mainly consisted of reticulated, pigmented macules, patches and plaques. The most common area of involvement was the chest in five cases.[] Skin markings are preserved, or in the neck and axillae, they may be exaggerated.[]

  • Klinefelter Syndrome

    In these individuals, the classic features of Klinefelter syndrome may be exaggerated, with low I.Q. or moderate to severe mental retardation also occurring.[] The skin was also abnormal, with atrophic skin plaques and areas of telangiectasia along the lines of Blaschko. The karyotype was 47,XXY (Klinefelter syndrome).[] Nearly all patients were severely mentally retarded, with IQ levels usually ranging from 20 to 60. 96 In contrast to 47,XXY patients, 49,XXXXY patients often exhibit micropenis[]

  • Phenylketonuria

    Untreated patients usually exhibit severe mental retardation and poor motor function, with characteristic T2 white matter signal abnormalities on conventional MR images.[] […] the image below); it can be striking in black and Japanese patients, although not all untreated patients are fair; treated patients often have typical pigmentation Fair skin[] Clinical findings included hair hypopigmentation, microcephaly, severe mental retardation with absent development of verbal language and autistic symptoms in all three patients[]

  • Basal Cell Carcinoma

    The skin appears as a crusted plaque that resembles a scar.[] mental retardation, likely associated with genes located within the 4.3Mb deleted region, especially.[] The main characteristics are: Slowly growing plaque or nodule Skin coloured, pink or pigmented Varies in size from a few millimetres to several centimetres in diameter Spontaneous[]

  • Cutis Laxa

    While the patients with GORAB mutations have severe osteopenia, the patients with PYCR1 mutations have severe mental retardation.[] A brief review of penicillamine induced skin changes, specifically cutis laxa and milia en plaque, is presented.[] mental retardation.[]

  • Patterson Pseudoleprechaunism Syndrome

    The features of this connective tissue and neuroendocrine disorder include bronzed hyperpigmentation, cutis laxa of the hands and feet, bodily disproportion, severe mental[] Jaundice - bronze skin Kaposi's Sarcoma - dark spots Kaposiform hemangio-endothelioma - dark skin plaque Keratosis - red-brown skin Lipodermatosclerosis - brown skin Lipoid[] mental retardation, and major bony deformities.[]

Further symptoms