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57 Possible Causes for Severe Onychodystrophy, Thick Wiry Hair

  • Hidrotic Ectodermal Dysplasia

    What to be alert for in the history --Abnormally thick and wiry hair in infancy --Progressive alopecia with age --Progressively dystrophic nails --Palmoplantar changes --Painful[dermatologyadvisor.com] In infancy, scalp hair is wiry, brittle, patchy, and pale; progressive hair loss may lead to total alopecia by puberty.[en.wikipedia.org] […] with age --Distal onycholysis --Micronychia or partial anonychia --Paronychia common Hair findings ( Figure 1 ) Figure 1.[dermatologyadvisor.com]

  • Craniofrontonasal Dysplasia

    wiry hair, and occasionally cleft lip and/or palate.[genedx.com] wiry hair with orbital asymmetry and strabismus. 5 The extracranial features include multiple skeletal malformations, such as sloping shoulders, dysplastic clavicles, thoracic[ncbi.nlm.nih.gov] , wiry, and curly hair at 2-3 months Defects in formation of toes and fingers, broad fingers and toes, curved last finger Increased webbing in between the fingers and toes[dovemed.com]

    Missing: Severe Onychodystrophy
  • Acrodermatitis Continua of Hallopeau

    Involvement of the adjacent nail bed and matrix frequently result in severe onychodystrophy or even anonychia.[ncbi.nlm.nih.gov] Nails showed severe onychodystrophy with confluent pustules covering the nail bed; however, the left fourth and right second, third, and fourth toenails were spared (Fig.[ncbi.nlm.nih.gov]

    Missing: Thick Wiry Hair
  • Alopecia Areata

    Nail examination revealed severe onychodystrophy of all 20 nails, including onycholysis, onychorrhexis and leukonychia (fig. 1 b).[karger.com]

    Missing: Thick Wiry Hair
  • Cronkhite-Canada Syndrome

    A 67-year-old man with nausea, appetite loss, frequent diarrhea and severe weight loss presented with alopecia, skin hyperpigmentation and onychodystrophy.[ncbi.nlm.nih.gov] On subsequent days of the stay in the hospital he developed hypogeusia and showed onychodystrophy.[ncbi.nlm.nih.gov] Endoscopy of Upper GI and Lower GI tract revealed severe gastroduodenitis with polyp in duodenum and multiple polyps whole throughout the colon respectively.[ncbi.nlm.nih.gov]

    Missing: Thick Wiry Hair
  • Muscular Dystrophy

    […] and severe muscle atrophy mainly affecting the extremities.[ncbi.nlm.nih.gov] On physical examination as an adult, we observed diffuse non-scarring alopecia on the scalp, onychodystrophy (pachyonychia) in all 20 nails, dental decay, mild dysphonia,[ncbi.nlm.nih.gov]

    Missing: Thick Wiry Hair
  • Trichotillomania

    hairs they describe as being different from the rest (eg, "wiry," "thick," "stubby," "kinky," or of a darker color). 19 Unfortunately, the trauma of pulling, which damages[web.archive.org] hairs they describe as being different from the rest (eg, “wiry,” “thick,” “stubby,” “kinky,” or of a darker color). 19 Unfortunately, the trauma of pulling, which damages[dx.doi.org] Often, children with TTM will scrutinize and then touch or stroke the hair before pulling. 16, 18 Hairs are usually pulled out individually, and often patients will select[web.archive.org]

    Missing: Severe Onychodystrophy
  • Autosomal Recessive Deafness 24

    […] or developmental delay, and seizures (generalized tonic-clonic, myoclonic, partial, and absence seizures) which sometimes increase in severity over time.[epilepsygenetics.net] DOORS syndrome is characterized by profound sensorineural hearing loss, onychodystrophy (short or absent nails), osteodystrophy (short terminal phalanges), intellectual disability[epilepsygenetics.net]

    Missing: Thick Wiry Hair
  • Acroosteolysis Dominant Type

    Clinically, PPK begins focally in infancy and then becomes diffuse and severe.[emedicine.medscape.com] Progressive, well-defined perioral, perianal, and perineal hyperkeratotic plaques are present, as is onychodystrophy.[emedicine.medscape.com]

    Missing: Thick Wiry Hair
  • Epidermolysis Bullosa Simplex

    […] and severe muscle atrophy mainly affecting the extremities.[ncbi.nlm.nih.gov] On physical examination as an adult, we observed diffuse non-scarring alopecia on the scalp, onychodystrophy (pachyonychia) in all 20 nails, dental decay, mild dysphonia,[ncbi.nlm.nih.gov]

    Missing: Thick Wiry Hair

Further symptoms