Severe-osteoporosis: Causes & Reasons

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Possible Causes for severe osteoporosis

Osteoporosis

The challenge is further compounded in severe osteoporosis when the cortical thickness is affected more severely. [ncbi.nlm.nih.gov]

A 38-year-old man had been diagnosed with severe osteoporosis most likely due to chronic SIADH. The SIADH was believed to be idiopathic. [ncbi.nlm.nih.gov]

We present a patient with multiple vertebral fractures in the context of severe osteoporosis, who, in the course of investigation for intractable spine and hip pain, was found [ncbi.nlm.nih.gov]

Vertebral Compression Fracture

Nonunion of L3 with severe spinal stenosis was recognized in the preoperative films. Bone mineral analysis showed severe osteoporosis with a T-score of -4.7. [ncbi.nlm.nih.gov]

BACKGROUND: Teriparatide (recombinant human parathyroid hormone 1-34) is increasingly used for the treatment of severe osteoporosis because it stimulates bone formation and [ncbi.nlm.nih.gov]

In severe osteoporosis, the vertebrae become so weak that they collapse upon themselves, leading to spinal deformity. [my.clevelandclinic.org]

Nestor-Guillermo Progeria Syndrome

osteoporosis, and marked osteolysis. [uniprot.org]

[MIM:614008]: An atypical progeroid syndrome characterized by normal development in the first years of life, later followed by the emergence of generalized lipoatrophy, severe [genecards.org]

Definition An atypical progeroid syndrome characterized by normal development in the first years of life, later followed by the emergence of generalized lipoatrophy, severe [uniprot.org]

Senile Osteoporosis

Our sample consisted of 40 elderly women of the mean age of 78 /-5 years, having severe osteoporosis. [ncbi.nlm.nih.gov]

severe osteoporosis. [ncbi.nlm.nih.gov]

Therefore, rapamycin might be a feasible therapeutic approach for senile osteoporosis. [ncbi.nlm.nih.gov]

Lumbar Compression Fracture

Treatment options vary since these patients are elderly and most have medical co-morbidities with severe osteoporosis. [cureus.com]

osteoporosis. 2-4 Old vs. [dynamicchiropractic.com]

osteoporosis.2-4 Old vs. [dynamicchiropractic.com]

Osteoporosis-Pseudoglioma Syndrome

Abstract Isteoporosis-pseudoglioma syndrome (OPPG) is a rare heritable entity that features severe osteoporosis and many variable ophthalmic findings leading to congenital [ncbi.nlm.nih.gov]

Osteoporosis-pseudoglioma syndrome is an autosomal recessive syndrome combining severe premature osteoporosis with a bilateral eye disorder leading to early onset of blindness [ncbi.nlm.nih.gov]

OBJECTIVES: To determine whether intravenous bisphosphonate treatment is helpful for children with osteoporosis pseudoglioma syndrome who have severe osteoporosis. [ncbi.nlm.nih.gov]

Vitamin D Deficiency

Examination results showed severe osteoporosis; both technetium-99m-sestamibi scintigraphy and computed tomography showed an abnormal nodule in the mediastinum, which was [ncbi.nlm.nih.gov]

Prolonged deficiency of vitamin D can cause onset of severe and debilitating conditions, such as fractures, rickets and osteoporosis. [symptoma.com]

Vitamin D deficiency can lead to a loss of bone density, which can contribute to osteoporosis and fractures. Severe vitamin D deficiency can also lead to other diseases. [medlineplus.gov]

Osteopenia and Osteoporosis

Features of Osteoporosis patients 11.1 Cardiovascular and metabolic comorbidities 11.2 Arthritis in patients with osteoporosis 11.3 Respiratory comorbidities 11.4 Severe Osteoporosis [globenewswire.com]

Osteoporosis is considered more serious than osteopenia because the extent of the bone loss is more severe. [medicalnewstoday.com]

Both osteopenia and osteoporosis remain largely under diagnosed because of their asymptomatic nature, especially in the less severe stages of bone loss. [globenewswire.com]

Idiopathic Juvenile Osteoporosis

Bone mineral density (BMD) showed severe osteoporosis [Table 2]. [jnsbm.org]

Studies of young patients with severe osteoporosis. Medicine (Baltimore). 1997, 76: 266-283. 10.1097/00005792-199707000-00005. [ped-rheum.biomedcentral.com]

Two patients with idiopathic juvenile osteoporosis were siblings and one patient with idiopathic juvenile osteoporosis had a daughter with severe osteogenesis imperfecta [ncbi.nlm.nih.gov]

Premature Aging Type Okamoto

[…] erythroid macrocytosis severe developmental delay. [malacards.org]

[…] mellitus, osteoporosis, erythroid macrocytosis, severe growth and developmental deficiency" Am J Med Genet. 1997 Mar 17;69(2):169-70 The statements on this Web site have [wellnessadvocate.com]

Heritability: Autosomal recessive inheritance AKA: premature aging syndrome with osteosarcoma cataracts diabetes osteoporosis erythroid macrocytosis severe developmental delay [monarchinitiative.org]

Vaginitis

Estrogen and adjuvants may be best.[9] Topical treatment with estrogen is effective when the symptoms are severe and relieves the disruption in pH to restore the microbiome [en.wikipedia.org]

Those women who are survivors of hormone-sensitive cancer may need to be treated more cautiously.[1] Some women can have symptoms that are widespread and may be at risk for osteoporosis [en.wikipedia.org]

X-Linked Osteoporosis with Fractures

osteoporosis deformed, gracile (over-tubulated) bones cortical thinning hyperplastic callus formation popcorn calcification : the metaphyses and epiphyses exhibit numerous [radiopaedia.org]

osteoporosis. [nytimes.com]

In severe osteoporosis, thin bones or vertebral fractures may be seen on simple X-rays.. [yourhormones.info]

Vitamin B12 Deficiency

Thanks to its association with the amino acid homocysteine, vitamin B12 is touted for its supposed ability to help several conditions. [livescience.com]

High levels of homocysteine are commonly found in people with osteoporosis, dementia, heart disease, cognitive impairment and depression. [livescience.com]

Cystitis

[…] capital coxa vara: occasionally seen in severe osteoarthritis and Legg-Perthes' disease Associations congenital dislocation of hip - developmental hip dysplasia faulty development [radiopaedia.org]

secondary to tuberculosis or other infection secondary to other underlying bone diseases such as: osteogenesis imperfecta cretinism dyschondroplasia(s) Paget's disease osteoporosis [radiopaedia.org]

Fracture

Although most fractures are caused by trauma, they can be “pathologic” (caused by an underlying disease such as cancer or severe osteoporosis). [my.clevelandclinic.org]

In people with severe osteoporosis, a VCF may be caused by simple daily activities, such as stepping out of the shower, sneezing vigorously or lifting a light object. [aans.org]

People break bones in sports injuries, car accidents, falls, or from osteoporosis (bone weakening due to aging). [my.clevelandclinic.org]

Primary Pigmented Nodular Adrenocortical Disease

As the clinical presentation of Cushing syndrome in this group of patients may be atypical (severe osteoporosis or short stature), the detection of multiple, small adrenocortical [ncbi.nlm.nih.gov]

The first was a thirteen and a half year old male who presented with Cushing syndrome for three years and severe osteoporosis. [ncbi.nlm.nih.gov]

Patients with PPNAD often present with atypical CS, which is characterized by an asthenic, rather than obese, body habitus caused by severe osteoporosis, short stature and [orpha.net]

Exostosis

The patient had history of severe osteoporosis with multiple fractures and was on teriparatide for 16 months. [ncbi.nlm.nih.gov]

Viral Disease

Although more often diagnosed in older women, osteoporosis can affect anyone but there are several lifestyle changes you can make to keep your bones in the best health possible [drugs.com]

Finished: The ABC's of Hepatitis: Get to Know This Viral Disease DON'T MISS Osteoporosis: A Battle For Your Bones Osteoporosis is a condition where bones become weak and brittle [drugs.com]

Gingivitis

One form of gingivitis, called acute necrotizing ulcerative gingivitis, develops quickly and causes moderate to severe pain. [1800dentist.com]

[…] women will have preterm, low birth weight babies - Aggravate existing health conditions - Contribute to new medical problems including, diabetes, respiratory disease and osteoporosis [1800dentist.com]

Anemia

dermatitis herpetiformis and gluten ataxia are among the most commonly seen characteristics In the paediatric population, coeliac disease can lead to severe growth disorders [doi.org]

[…] malabsorption These concurrent conditions can affect various systems and organs, and include manifestations in the skin, musculoskeletal and central nervous system Anaemia, osteoporosis [doi.org]

Thyrotoxicosis Factitia

osteoporosis) Weight loss Prevention Thyroid hormone should be taken only by prescription and under the supervision of a provider. [health.firstlighthealthsystem.org]

osteoporosis) Weight loss Infertility Problems sleeping When to Contact a Medical Professional Contact your provider if you have symptoms of hyperthyroidism. [ufhealth.org]

[…] complications as untreated or improperly treated hyperthyroidism may develop: Abnormal heartbeat (atrial fibrillation) Chest pain (angina) Heart attack Loss of bone mass (if severe [health.firstlighthealthsystem.org]

Alcohol Abuse

Common medical side effects include: High blood pressure Sexual problems Cancer Stomach problems Osteoporosis, especially in women Alcoholism often causes severe social consequences [timberlineknolls.com]

Ganglion Cyst

The stress fracture was thought to have resulted from several factors, including structural weakness due to bony absorption from the ganglion cyst, osteoporosis that induced [ncbi.nlm.nih.gov]

Hypogonadism

Infertility Osteoporosis HIV-associated weight loss Type 2 DM Obesity Metabolic syndrome Monitoring Regular follow-up needed in patients receiving testosterone therapy (Dohle [arupconsult.com]

Severe hypogonadism can also cause mental and emotional changes. [mayoclinic.org]

osteoporosis might be prescribed bisphosphonates to preserve bone mass, in addition to hormone replacement therapy.[21] Genetics[edit] The genetic and molecular basis of [en.wikipedia.org]

Cold Exposure

Premature closure of epiphyses in children; osteoporosis. Muscle atrophy. [patient.info]

Prognosis The prognosis depends on the severity and duration of the cold environment and the presence of any risk factors. [patient.info]

Atopy

Osteoporosis Osteoporosis is a disease that causes very weak bones that break easily. Women are five times more likely to get osteoporosis than men. [pueblo.gsa.gov]

adrenal suppression, osteoporosis, hypertension, diabetes, obesity, striae), their use should be limited to patients with severe disease. [clevelandclinicmeded.com]

Protect Your Identity: What Older Adults Should Know The Identity Protection Guide shares steps to help you protect your personal information and explores several options [pueblo.gsa.gov]

Periodontitis

The aim of this report was to discuss the administration period of BP in the treatment of osteoporosis, the decision-making and clinical management of severe MRONJ and the [ncbi.nlm.nih.gov]

[…] tissues may also play a role in the more severe consequences of the disease. [britannica.com]

[…] disease severity [7]. [medical-clinical-reviews.imedpub.com]

Dermatitis

Bone density scans for osteoporosis Several technologies can assess bone density, but the most common is known as dual energy x-ray absorptiometry (DEXA). 5 ways to boost [health.harvard.edu]

Because long-term use can cause potentially serious side effects like high blood pressure and osteoporosis, they’re usually only used for short periods to treat severe discomfort [innerbody.com]

Osteogenesis Imperfecta Type 13

OI13 is characterized by normal teeth, faint blue sclerae, severe growth deficiency, borderline osteoporosis, severe bone deformity, and recurrent fractures affecting both [malacards.org]

Frontal radiograph of the leg in a patient with type I osteogenesis imperfecta (OI) shows evidence of severe osteoporosis, overtubulation of both the tibia and fibula, and [emedicine.medscape.com]

Other features include severe osteoporosis by DEXA. Type VI Manifestations include moderate-to-severe deformities. They may have blue sclera. [ijem.in]

Esophagitis

Methods We describe three patients who had severe esophagitis shortly after starting to take alendronate and also analyze adverse esophageal effects reported to Merck, the [nejm.org]

Only a fraction of individuals develop severe adverse esophageal reactions to the drug. [archivesofpathology.org]

References 452 Citing Articles Letters Abstract Background Alendronate, an aminobisphosphonate and a selective inhibitor of osteoclast-mediated bone resorption, is used to treat osteoporosis [nejm.org]