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2 Possible Causes for Severe Prenatal Onset Hydrocephalus

  • Macrocephaly

    Of those, a fraction (7/16) will have severe obstructive hydrocephalus of unknown etiology that requires ventricular shunting [ Muller et al 2012 ].[ncbi.nlm.nih.gov] Approximately 20% of individuals with 9q22.3 microdeletion have prenatal onset of macrosomia characterized by birth length and weight above the 95 th centile, which continues[ncbi.nlm.nih.gov]

  • Gorlin Syndrome

    Of those, a fraction (7/16) will have severe obstructive hydrocephalus of unknown etiology that requires ventricular shunting [ Muller et al 2012 ].[ncbi.nlm.nih.gov] Approximately 20% of individuals with 9q22.3 microdeletion have prenatal onset of macrosomia characterized by birth length and weight above the 95 th centile, which continues[ncbi.nlm.nih.gov]

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