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105 Possible Causes for Severe Thrombocytopenia (Birth

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  • Amegakaryocytic Thrombocytopenia

    […] as a severe thrombocytopenia at birth due to ineffective megakaryocytopoiesis and no characteristic physical anomalies.[] In the last 10 years, we collected data from 20 patients diagnosed with CAMT based on a severe thrombocytopenia since birth and absent or markedly decreased numbers of megakaryocytes[] Although both are characterized by severe ( 50,000/microL) thrombocytopenia at birth, the molecular mechanisms underlying these disorders and their clinical presentations[]

  • Thrombocytopenia

    Four (8%) infants had severe thrombocytopenia (counts 50,000/μL) at birth.[] The isolated thrombocytopenia is severe, with the platelet count being below 20 10 9 /L.[] Three variables had predictive correlations: (1) gestational age at birth (shorter gestation was associated with higher likelihood of severe, persistent thrombocytopenia);[]

  • Toxoplasmosis

    […] delay, thrombocytopenia and anaemia.[] May have no apparent symptoms at birth, with complications developing only later in life.[] Neonatal features of infection vary and include hydrocephalus, microcephaly, intracranial calcifications, chorioretinitis, strabismus, severe sight impairment, epilepsy, developmental[]

  • Growth Failure

    One patient died at the age of 6 months following severe infections from birth and therefore developmental data is not available (F10).[] Marked Thrombocytopenia with Milder Leukopenia Occurs Frequently in Early to Mid-Childhood Nine patients ( 80%) have had documented cytopenia requiring platelet transfusions[]

  • Fetal and Neonatal Alloimmune Thrombocytopenia

    It occurs in approximately 1 in 1000 live births and is the most common cause of severe thrombocytopenia in fetuses and term neonates.[] Outcome was neonatal platelet (PLT) count at birth and amount of severe thrombocytopenia. Furthermore the appearance of ICH was analyzed.[] CONCLUSIONS: All neonates with thrombocytopenia at birth should be evaluated for FNAIT.[]

  • Abruptio Placentae

    Women who had thrombocytopenia (platelet count, The risk factors for preeclampsia were derived from data obtained before randomization.[] Neonatal outcome data included gestational age, preterm birth ( 10 ), admission to a neonatal intensive care unit, and neonatal complications.[] 110 mm Hg no more than one week before delivery if the woman had been treated with an antihypertensive drug), plus one of the following: increasing proteinuria, persistent severe[]

  • Cholestasis

    After birth at 33   0 weeks the newborn presented only transfused RBCs and suffered from anemia, thrombocytopenia, leukopenia, and a cholestatic liver disease.[] The fetus developed fetal anemia and a severe hydrops requiring three intrauterine red blood cell (RBC) transfusions.[]

  • Infantile Hepatic Hemangioendothelioma

    It is clinically evident within the first six months after birth and can be life threatening because of heart failure, intraperitoneal hemorrhage or thrombocytopenia.[] In less severe forms spontaneous regression has been described.[]

  • Thrombocytopenia Due to Sequestration

    The thrombocytopenia improves over time], Congenital amegakaryocytic thrombocytopenia (CAMT) [CAMT severe thrombocytopenia presenting at birth or shortly thereafter with no[] Four (8%) infants had severe thrombocytopenia (counts 50,000/μL) at birth.[] Severe Thrombocytopenia in the neonates ( 120. CAMT Course : Severe CAMT is recognized during the first few days of birth due to easy bleeding/bruising.[]

  • Kasabach Merritt Syndrome

    Hemogram revealed anemia severe thrombocytopenia, prolongation of bleeding, clotting time and increased fibrin degradable products, suggestive of KMS.[] KMS is characterized by giant hemangiomas and severe thrombocytopenia, which may result in life-threatening multi-organ hemorrhage.[] A 14-month old female child was brought with a reddish lesion on the left scapular area noticed at birth, which suddenly increased in size since 3 days.[]

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