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5 Possible Causes for Severely Reduced Central Responses on Multifocal ERG

  • Macular Dystrophy with Central Cone Involvement

    ERG responses to full-field testing are normal but multifocal studies reveal severely reduced central responses.[disorders.eyes.arizona.edu]

  • Goldmann-Favre Syndrome

    […] plateau Multifocal ERG: preserved central responses but reduced with increasing eccentricity EOG light rise undetectable 5 OD: 6.5/6.5/5 OS: 6.5/6/4.5 Severely delayed and[iovs.arvojournals.org] reduced 40/36 Present OFF response plateau Multifocal ERG: preserved central responses but reduced with increasing eccentricity 6 OD: 56/ 100/8.5 Not detectable 10/10 NP[iovs.arvojournals.org] […] response to more peripheral hexagons 3 OD: 8/8.5/13.5 OS: 12.5/9.5/14 Delayed and reduced 6/6 NP NP — 4 OD: 6/6/7 OS: 7.5/6.5/6.5 Normal amplitude, delayed 50/46 Present OFF response[iovs.arvojournals.org]

  • Occult Macular Dystrophy

    The multifocal ERGs 4 demonstrated a loss of local responses in the central retina (fig 2C).[bjo.bmj.com] However, focal macular ERGs with 5, 10, and 15 degrees stimulus spots 3 were severely reduced and essentially absent (fig 2B).[bjo.bmj.com]

  • Peripheral Cone Dystrophy

    Multifocal electroretinography (mfERG) showed well-preserved local responses in the central retina and severely reduced responses in the perifoveal retina (Fig. 1) corresponding[journals.lww.com] The results of mfERGs showed slightly detectable responses in the central area of left eye; however, the amplitudes of the other area were severely reduced in the patients[link.springer.com] Full-field ERG disclosed normal scotopic responses in both eyes but diminished photopic amplitudes (Fig. 2).[journals.lww.com]

  • Quinine

    Slow stimulus (base period of 83 ms) multifocal electroretinogram (ERG) showed electronegative responses outside the inner 5 degrees, with a reduced but electropositive response[ncbi.nlm.nih.gov] […] seen in this central area.[ncbi.nlm.nih.gov] VA recovered to 6/6 right eye and 6/12 left eye, though severely constricted fields were noted.[ncbi.nlm.nih.gov]

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