Sezary Cell: Causes & Reasons

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Possible Causes for Sezary Cell

Mycosis Fungoides

Sezary cells have a type 2 helper T cell cytokine profile. [omim.org]

cells ( B0a - Clone negative B0b - Clone positive B1 - Circulating Sezary cells (≥5% of lymphocytes) B1a - Clone negative B1b - Clone positive B2 - High blood tumor burden [en.wikibooks.org]

B1: Low numbers of Sezary cells in the blood (more than in B0 but less than in B2). B2: High number of Sezary cells in the blood. [cancer.org]

Cutaneous T-Cell Lymphoma

[…] don't contain cancer cells There may be a small number of Sezary cells in the blood or there may be none Stage IV Skin is dry, red, scaly, or bumpy, and may have tumors on [hopkinsmedicine.org]

[…] mononuclear (cerebriform) cells in the skin, lymph nodes, and peripheral blood (sezary cells) A form of cutaneous t-cell lymphoma, a cancerous disease that affects the skin [icd9data.com]

[…] lesions), or bumps on the skin There are a small number of Sezary (lymphoma) cells in the blood Lymph nodes are normal (not swollen or enlarged) Stage II Dry, red, scaly [hopkinsmedicine.org]

Sézary Syndrome

Sezary cells can be found circulating in the blood in advanced stages of Sezary syndrome. [news.cancerconnect.com]

Sezary syndrome is a rare form of primary cutaneous T cell lymphoma. [ncbi.nlm.nih.gov]

It is characterized by the triad of generalized erythroderma, lymphadenopathy, and neoplastic T cells (Sezary cells) in the skin, lymph nodes, and peripheral blood. [ncbi.nlm.nih.gov]

Mycosis

Sezary cells have a type 2 helper T cell cytokine profile. [omim.org]

cells ( B0a - Clone negative B0b - Clone positive B1 - Circulating Sezary cells (≥5% of lymphocytes) B1a - Clone negative B1b - Clone positive B2 - High blood tumor burden [en.wikibooks.org]

B1: Low numbers of Sezary cells in the blood (more than in B0 but less than in B2). B2: High number of Sezary cells in the blood. [cancer.org]

T-Cell Prolymphocytic Leukemia

Cytologically, the T-PLL cells were round (n = 16) or Sezary cell-like (n = 3). [ncbi.nlm.nih.gov]

Matutes E, Keeling DM, Newland AC, Scott CS, Mitchell D, Traub N, et al. (1990) Sezary cell-like leukemia: a distinct type of mature T cell malignancy. [link.springer.com]

Sezary syndrome is a form of mycosis fungoides, a T-cell lymphoma that occurs only on the skin. [tnoncology.com]

T-Cell Lymphoma Type 1A

B1: Low numbers of Sezary cells in the blood (more than in B0 but less than in B2). B2: High number of Sezary cells in the blood. [cancer.org]

(Sezary cells) in the blood Stage 4 is divided into 3 groups: stage 4A1 means there are high numbers of cancerous T cells (Sezary cells) in the blood (Sezary syndrome) stage [cancerresearchuk.org]

Localized Pagetoid Reticulosis

In Sezary's syndrome Sezary cells with more lobulated nuclei than in mycosis cells and lymphoblast-like cells as in mycosis fungoides could be found. [thedoctorsdoctor.com]

Sezary cell counts in erythrodermic cutaneous T-cell lymphoma: implications for prognosis and staging. Leuk Lymphoma 2006; 47: 1841-56. 7. [ispub.com]

At diagnosis, peripheral blood samples should be analyzed for total white cell, lymphocyte and Sezary cell counts, serum LDH, liver and renal function, lymphocyte subsets, [e-ijd.org]

Folliculotropic Mycosis Fungoides

Quantitation of neoplastic T lymphocytes within the peripheral blood (Sezary cells) is also performed, either by manual differential, flow cytometry, or both. [cancertherapyadvisor.com]

Glomerular disease and urinary sezary cells in cutaneous t-cell lymphomas. Am J Kidney Dis 1993;21:545-7. [ PUBMED ] [Figure 1], [Figure 2], [Figure 3] [ijdvl.com]

Sezary syndrome is a leukemic variant.Mycosis fungoides (MF) is an epidermotropic, primary cutaneous T cell lymphoma (CTCL) characterized by infiltrates of small to medium [camosaxomidegucamus.xpg.com.br]

Primary Cutaneous Lymphoma

[…] and cells specific to certain skin lymphomas, such as Sezary cells. [cityofhope.org]

Sezary Syndrome Sezary syndrome accounts for approximately 15% of cutaneous T-cell lymphoma cases ( Cutaneous Lymphoma Foundation 2012 ). [bmc.org]

[…] a poor prognosis (Sezary syndrome and peripheral T-cell lymphoma) and forms with a variable prognosis (pleomorphic small/medium-sized T-cell lymphoma, subcutaneous panniculitis-like [orpha.net]

T-Cell Lymphoma

Cohort Status Cohort 1 Cutaneous T-cell Lymphoma (mycosis fungoides or Sezary syndrome)-2 or fewer. [clinicaltrials.gov]

In the first patient (aged 30) repeated examinations confirmed presence of Sezary cells in peripheral blood samples, dominant T-cell clone in the skin, peripheral blood and [content.sciendo.com]

Primary Cutaneous Follicle Center Lymphoma

This Sezary cell is the malignantCirculating Sezary Cell pleomorphic T cellseen in mycosis fungoides and has a convoluted nucleus 10.  Sezary cells are mononuclear cells [slideshare.net]

[…] and cells specific to certain skin lymphomas, such as Sezary cells. [cityofhope.org]

Sezary syndrome can affect people of any age, but it usually occurs in people over age 50 and is slightly more common in men. [seattlecca.org]

Granulomatous Slack Skin

Page 34 - The histologic spectrum of mycosis fungoides/Sezary syndrome (cutaneous T-cell lymphoma). [books.google.com]

At diagnosis, peripheral blood samples should be analyzed for total white cell, lymphocyte and Sezary cell counts, serum LDH, liver and renal function, lymphocyte subsets, [e-ijd.org]

Blood tests may also be performed to detect the presence of characteristic cells (Sezary cells) in individuals with suspected Sezary syndrome. [rarediseases.org]

Follicular Mucinosis

cell neoplasia. [ncbi.nlm.nih.gov]

[…] lymphoma, Sezary syndrome, Hodgkin lymphoma, acute myeloblastic leukemia, chronic lymphocytic lymphoma and squamous cell carcinoma of the tongue Nodular or plaquelike lesion [pathologyoutlines.com]

Primary follicular mucinosis: Long-term follow-up of patients younger than 40 years with and without clonal T-cell receptor gene rearrangement. [thedoctorsdoctor.com]

Dendritic Cell Sarcoma Not Otherwise Specified

T-cell lymphoma Mycosis fungoides / Sezary syndrome Anaplastic large cell lymphoma, T/null cell, primary cutaneous type Anaplastic large cell lymphoma, T/null ell, primary [en.wikibooks.org]

Sezary Syndrome/Mycosis Fungoides; Peripheral T-Cell Lymphoma, Not Otherwise Specified; Angioimmunoblastic T-Cell Lymphoma; Anaplastic Large Cell Lymphoma, ALK Positive; [springerpub.com]

Fungoides/Sezary syndrome ▪ Lymphomatoid Papulosis ▪ Cutaneous anaplastic large cell lymphoma ▪ Subcutaneous panniculitis-like T-cell lymphoma ▪ Primary cutaneous gamma-delta [enjoypath.com]

B-Cell Prolymphocytic Leukemia

T-cell lymphoma Mycosis fungoides / Sezary syndrome Anaplastic large cell lymphoma, T/null cell, primary cutaneous type Anaplastic large cell lymphoma, T/null ell, primary [en.wikibooks.org]

Sezary syndrome and ATLL are post-thymic T cell malignancies that must be distinguished from the T-cell chronic lymphoproliferative disorders. [web.archive.org]

[…] lymphoma/leukemia (HTLV1+) Extranodal NK/T-cell lymphoma, nasal type Enteropathy-type T-cell lymphoma Hepatosplenic gamma-delta T-cell lymphoma Subcutaneous panniculitis-like [en.wikibooks.org]

Hydroa Vacciniforme-Like Lymphoma

Although most people might know what breast carcinoma is, they might not be familiar with NK/T cell lymphomas (or try Mycosis Fungoides and Sezary Syndrome!). [oncocare.sg]

[…] lymphoma anaplastic immunoblastic pleomorphic lymphomatoid papulosis borderline cases Aggressive malignant CTCLs Sezary syndrome Large cell, CD30 -negative CTCLs immunoblastic [e-immunohistochemistry.info]

Sezary Syndrome, Mycosis Fungoides and variants are presented along with B-cell, CD30, lymphoproliferative disorders among others. [books.google.com]

Aggressive NK-Cell Leukemia

Although the absence of CD7 expression is considered to be a marker for the diagnosis of T cell leukemia/lymphomas such as Sezary cell leukemia and adult T cell leukemia associated [synapse.koreamed.org]

[…] are more aggressive than B-cell lymphomas. • Short account about Sezary syndrome. 3. [slideshare.net]

Mycosis fungoides and Sezary syndrome Variants: Pagetoid reticulosis MF-associated follicular mucinosis Granulomatous slack skin disease Angioimmunoblastic T-cell Iymphoma [dartmouth.edu]

Cutaneous Pseudolymphoma

Seite 34 - The histologic spectrum of mycosis fungoides/Sezary syndrome (cutaneous T-cell lymphoma). [books.google.de]

Sezary cells are also seen in peripheral smear. [ijdpdd.com]

Primary Cutaneous Anaplastic Large-Cell Lymphoma

Limfoamele mycosis fungoides / sindrom Sezary Cutaneous T-Cell Lymphomas: Mycosis Fungoides and Sézary cell lymphomas (mycosis fungoides and Sezary with mycosis fungoides. [mepidyxupewaz.xpg.uol.com.br]

Lymphoma cells called Sezary cells are found in the skin and the blood, and lymph nodes are often enlarged. [bmc.org]

Blood tests may also be performed to detect the presence of characteristic cells (Sezary cells) in individuals with suspected Sezary syndrome. [rarediseases.org]

Prolymphocytic Leukemia

Sezary cell leukemia (SCL) is a rare T cell neoplasia that has been suggested to be a variant of T-prolymphocytic leukemia (T-PLL). [ncbi.nlm.nih.gov]

Sezary cell leukaemia: a distinct T cell disorder or a variant form of T prolymphocytic leukaemia? Leukemia. 1997; 11 (7):1009–1013. [ PubMed ] 14. [ncbi.nlm.nih.gov]

[…] and Sezary syndrome. [cancertherapyadvisor.com]

Leontiasis Ossium

Bone marrow was infiltrated with Sezary cells. Sezary syndrome (SS) is the leukaemic phase of a primary cutaneous T-cell lymphoma, Mycosis Fungoides. [omicsonline.org]

In both the patients the total count of WBC were >50,000/mm 3 and characteristic Sezary cells were more than 80-90%, that is absolute count of Sezary cells were >1000/mm 3 [omicsonline.org]

In both cases leucocyte count was high and of which 80-90% were morphologically Sezary cells. [omicsonline.org]

Neutropenia and Hyperlymphocytosis with Large Granular Lymphocytes

[…] called Sezary cells. [writenowservices.com]

Sezary syndrome and ATLL are post-thymic T cell malignancies that must be distinguished from the T-cell chronic lymphoproliferative disorders. [med-ed.virginia.edu]

Circulating clonal CLA(+) and CD4(+) T cells in Sezary syndrome express the skin-homing chemokine receptors CCR4 and CCR10 as well as the lymph node-homing chemokine receptor [medicaljournals.se]

Basophil Adenoma

Mycosis fungoides/Sezary syndrome Anaplastic large-cell lymphoma, T/null cell, primary cutaneous type Peripheral T-cell lymphoma, not otherwise characterized... ‏ [books.google.com]

الصفحة 17 - Extranodal NK/T-cell lymphoma, nasal type Enteropathy-type T-cell lymphoma Hepatosplenic gamma-delta T-cell lymphoma Subcutaneous panniculitis-like T-cell lymphoma [books.google.com]

Component Complement 5 Deficiency

[…] mononuclear cells in the skin, lymph nodes, and peripheral blood (sezary cells). (12 Dec 1998) [kmle.co.kr]

[…] ichthyosiform erythroderma [医]先天性非大疱性鱼鳞状红皮病 Dominant congenital ichthyosiform erythroderma [医]先天性显性鱼鳞癣状红皮病 Recessive congenital ichthyosiform erythroderma [医]先天性隐性鱼鳞癣状红皮病 Sezary [fastdict.net]

[…] syndrome (the erythrodermic form of cutaneous T-cell lymphoma ) Several very rare congenital ichthyotic conditions Erythroderma may also be a symptom or sign of a systemic [dermnetnz.org]

Schlegelberger-Grote Syndrome

[…] form of cutaneous T-cell lymphoma. [methycancer.psych.ac.cn]

PubMedID 12393503 Title Molecular cytogenetic analysis of cutaneous T-cell lymphomas: identification of common genetic alterations in Sezary syndrome and mycosis fungoides [methycancer.psych.ac.cn]

Cancer Report Cancer : Mycosis fungoides/Sezary's syndrome Summary Cancer Name Mycosis fungoides/Sezary's syndrome Clinics and Pathology Epidemiology This is the most common [methycancer.psych.ac.cn]

Retroperitoneal Lymphoma

Repeated peripheral blood smear revealed younger lymphatic cells (5% were suspicious for Sezary cells). [cyberleninka.org]

Sezary syndrome C. ML, large cell immunoblastic D. Mycosis fungoidies E. [med-ed.virginia.edu]

A large single-center experience with allogeneic stem-cell transplantation for peripheral T-cell non-Hodgkin lymphoma and advanced mycosis fungoides/Sezary syndrome. [emedicine.medscape.com]

Hyperkeratosis Lenticularis Perstans

The inflammatory infiltrate in the HLP lesion was composed of small lymphocytes, which often displayed nuclei with deep infoldings resembling Sezary cells, and larger histiocytic [thedoctorsdoctor.com]

In summary, we describe a case of HLP showing ultrastructurally numerous vesicular bodies in the granular layer and Sezary cell-like lymphocytes and histiocytic cells containing [journals.lww.com]

Lymphomatoid Papulosis

The LyP type B lesion is characterized by a population of CD30 negative mononuclear cells with hyperchromatic cerebriform nuclei similar to the Sezary cell of mycosis fungoides [kjim.org]

Donate ONE ON ONE SUPPORT Menu What is Cutaneous Lymphoma Understanding My Diagnosis Cutaneous T-cell Lymphoma Mycosis Fungoides (MF) Sezary Syndrome (SS) Lymphomatoid Papulosis [clfoundation.org]

Sezary Syndrome (SS) Lymphomatoid Papulosis (LyP) Primary Cutaneous B-Cell Lymphoma (CBCL) Primary Cutaneous Anaplastic Large Cell Lymphoma (PCALCL) Patient Resources Navigating [clfoundation.org]

Parapsoriasis

In addition, CD7(-) Sezary cell lines, and Sezary cells within mycosis fungoides lesions, expressed galectin-1, whereas CD7-positive Sezary cell lines did not express galectin [thedoctorsdoctor.com]

Such cells have been variably termed "mycosis cells," "Lutzner cells" or "Sezary cells." Presence of individual haloed atypical lymphocytes within the epidermis. [dx.doi.org]

To determine specific characteristics of Sezary cells that contribute to galectin-1 resistance, we assessed CD7 expression and cell surface glycosylation of Sezary cells in [thedoctorsdoctor.com]

Zebra Body Myopathy

[…] lymphomas, for mycosis cells and Sezary cells may be inapparent by light microscopy, but are readily seen with TEM (1,6,7,19). [va.gov]

Sezary-Lutzner cells and Pautrier’s micro abscesses are found in Mycosis fungoides. 213. [mypgnotes.com]

Use of TEM is indicated for the pathologic study of skin and lymph node biopsies as well as buffy coats of peripheral blood from patients suspected of having cutaneous T-cell [va.gov]