Shagreen Patch Causes & Reasons

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Shagreen Patch Symptom Checker: Possible causes include Lymphangioleiomyomatosis. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.

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Patient File

Sex unknown, Age unknown

Reported Symptoms

Shagreen Patch,

Negated

None

Unsure

None

Possible Causes

Lymphangioleiomyomatosis

Besides facial angiofibromas and shagreen patches over the back, no other physical signs such as those referable to the respiratory system were noted. [nature.com]

patch Forehead plaque Retinal hamartoma Laboratory Findings Pulmonary function tests are used to assess the lung damage caused by lymphangiomyomatosis. [wikidoc.org]

Finally, signs consistent with TSC, such as facial angiofibromas, periungual fibromas, nail ridging and the shagreen patch, are seen in patients with TSC-LAM. [err.ersjournals.com]

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Tuberous Sclerosis

patches; and 14 lesions (12%), large shagreen patches. [ncbi.nlm.nih.gov]

Only 1 of 5 patients treated for shagreen patches showed improvement at 12 months. Treatment was well tolerated with no serious adverse events. [ncbi.nlm.nih.gov]

Diagnostic methods Diagnosis is based on presence of major (cortical dysplasias; subependymal nodules; SEGA; hypomelanotic macules ( 3, diameter 5 mm); shagreen patch; angiofibromas [orpha.net]

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Familial Cutaneous Collagenoma

Shagreen patches are most often associated with Tuberous sclerosis. [ozarkderm.com]

Shagreen patch: Shagreen patch is a collagenoma variant associated with tuberous sclerosis, a disease most commonly inherited in an autosomal dominant pattern. [emedicine.medscape.com]

FCC: Multiple, indurated cutaneous papulonodules that vary in size are located over the upper two thirds of the back Shagreen patch: Flesh-colored plaques of variable size [dermaamin.com]

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Subungual Fibroma

SHAGREEN PATCH- Leathery plaques of subepidermal fibrosis,usually situated on the trunk. 13. SHAGREEN PATCH. 14. [slideshare.net]

Other lesions which may be present (usually on the trunk) are shagreen patches (these are localized thickening of the skin with a rough surface) and ash-leaf patches (hypopigmented [mrcophth.com]

Shagreen Patch The shagreen patch is an area of thickened, elevated pebbly skin (like an orange peel) usually found on the lower back. It can be single or multiple. [tsalliance.org]

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Renal Fibroma

Shagreen patch was seen in the right lumbosacral region ( Fig. 1 b). [revistanefrologia.com]

Shagreen patch (connective tissue naevus). Cortical tuber. Subependymal nodule (SEN). Subependymal giant cell astrocytoma (SEGA). [patient.info]

patch Cerebral white matter migration lines Multiple retinal nodular hamartomas Gingival fibromas Cortical tuber Non-renal hamartoma Subependymal nodule Retinal achromatic [academic.oup.com]

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Subependymal Giant Cell Astrocytoma

Skin manifestations like shagreen patches were present in two, facial angiofibromas in three, periungal fibromas in two, hypopigmented macules in two and ash-leaf spot in [ncbi.nlm.nih.gov]

(J Child Neurol 1999;14:401) Major features Facial angiofibromas or forehead plaque Nontraumatic ungual or periungual fibroma Hypomelanotic macules (more than 3) Shagreen [pathologyoutlines.com]

Several facial and body hyperpigmented fibrous plaques and a posterior lumbar Shagreen patch were noted. 3. [hindawi.com]

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Third Trimester Pregnancy

Detailed examination of the skin and mucosa revealed Shagreen patches, nontraumatic subungual and gingival fibroma, all features of tuberous sclerosis complex. [degruyter.com]

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Angiomyolipoma

Shagreen patches (white arrows). C. Subungual fibromas in the hand (white arrows). D. Subungual fibromas in the feet (white arrows). [oatext.com]

Shagreen patch connective-tissue nevus composed of collagen, i.e. collagenoma.[11] Ash-leaf spots. Hypopigmented macules.[12] Lymphangioleiomyomatosis. SEGA. [librepathology.org]

patches) (3, 4). [ncbi.nlm.nih.gov]

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Zosteriform Lentiginosis

Patch,) Carney Complex (48 %) ( Lamb Syndrome, Name Syndrome,) Seborrheic Keratosis (48 %) ( Seborrheic Verruca, Senile Wart,) Grovers Disease (45 %) ( Benign Papular Acantholytic [gulfdoctor.net]

toxocariasis, tuberous sclerosis, Wyburn-Mason’s s. serpiginous snakelike lesions; larva migrans, lupus vulgaris, syphilis shagreen patch skin colored indurated plaque [dermadvocate.net]

Bathing Trunk Nevus, Congenital Nevomelanocytic Nevus, Garment Nevus, Giant Hairy Nevus, Nevus Pigmentosus Et Pilosus,) Connective Tissue Nevus (48 %) ( Collagenoma, Elastoma, Shagreen [gulfdoctor.net]

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Benign Cephalic Histiocytosis

Patch,) Differentials from Google. [gulfdoctor.net]

( Infantile Papular Acrodermatitis, Papular Acrodermatitis Of Childhood, Papulovesicular Acrolocated Syndrome,) Connective Tissue Nevus (57 %) ( Collagenoma, Elastoma, Shagreen [gulfdoctor.net]

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Hamartoma of the Central Nervous System

patches -Minimal to no risk of malignant transformation of skin lesions -Skin lesions tend to increase in size and number through puberty, and then tend to stabalize over [pedclerk.bsd.uchicago.edu]

Major features are cortical tubers, subependymal nodules, subependymal giant cell astrocytomas (SEGA), hypomelanotic skin macules, shagreen patches, retinal nodular hamartomas [neuropathology-web.org]

Salient dermatologic findings of TSC are hypopigmented macules (ash-leaf spots), shagreen patches, periungual fibromas, and adenoma sebaceum. [emedicine.medscape.com]

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Rhabdomyoma of the Myocardium

A shagreen patch was present in the right lower lumbar region. Patient was put on valproate. Patient became conscious and oriented over a span of 1 h. [mjdrdypu.org]

Finally, about the other lesions of TSC, we found hypomelanotic macules in all, facial angiofibroma in 45,1% and shagreen patches in only 19,3%. [bmccardiovascdisord.biomedcentral.com]

patch, facial angioma's, hypomelanotic macules and periungal fibromas. [mjdrdypu.org]

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Cystic Lung Disease

Patients with TSC usually present angiomyolipomas, angiofibromas, hypopigmented macules, shagreen patch, and/or periungual fibromas. [archbronconeumol.org]

patches (rough, elevated lesions commonly seen on the lower back) Hypomelanotic macular lesions, also referred to as ash leaf lesions (oval or ash leaf-shaped lesions with [thelamfoundation.org]

Angiofibromas (acne-like small reddish nodular lesions on the face, especially the nose and cheeks) Subungual fibromas (fibrous nodules arising around or beneath the nails) Shagreen's [thelamfoundation.org]

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Brain Neoplasm

patches, incr. incidence of subependymal astrocytomas hemangiomas in skin, mucosa, organs, bilat renal cell carcinoma, hemangioblastoma in retina, brain stem, and cerebellum [brainscape.com]

[…] in CNS and skin, angiofibromas, mitral regurgitation, ash-leaf spots, cardiac rhabdomyoma, (tuberous sclerosis, autosomal dOminant), MR, renal angiomyolipoma, seizures, shagreen [brainscape.com]

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Severe Idiopathic Pneumococcemia

patch (raised orange peel appearance) adenoma sebaceum (skin colored or pink lesion often present on face in late childhood to early adolescence) - which is a misnomer as [brainscape.com]

[…] rash on the back lasts 4-6 weeks nobody knows what causes it itchy The classic lesions are: - ash leaf macule (often present at birth, most easily seen with a wood's lamp) shagreen [brainscape.com]

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Hereditary Mucoepithelial Dysplasia

Shagreen patches can be seen in patients with: a. Multiple Hamartoma syndrome b. Hereditary hemorrhagic telangictasia c. Tuberous sclerosis * d. [fac.ksu.edu.sa]

/periungual fibromas, shagreen patches, ash-leaf spots, CNS findings (seizures, mental retardation), cardiac rhabdomyomas, and angiomyolipoma CNS findings associated with [studystack.com]

• Two other characteristic skin lesions are • connective tissue hamartomas –shagreen patches • ovoid areas of hypopigmentation -ashleaf spots. [slideshare.net]

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Familial Papillary Thyroid Carcinoma with Papillary Renal Cell Carcinoma

patches, and hypopigmented macules. [jmg.bmj.com]

[…] disease involving multiple tissues and organs. 34 The patients present with dermatological lesions such as facial angiofibromas (adenoma sebaceum), periungual fibromas, shagreen [jmg.bmj.com]

[…] dominant disease involving multiple tissues and organs.34 The patients present with dermatological lesions such as facial angiofibromas (adenoma sebaceum), periungual fibromas, shagreen [jmg.bmj.com]

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Carcinoma of the Breast

patch and elastic tissue nevus. [ncbi.nlm.nih.gov]

[…] skin tags”; when the reticular dermis is involved mostly, the abnormality may be of collagen, elastic tissue, acid mucopolysaccharides, or any combination of them, as in shagreen [ncbi.nlm.nih.gov]

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Hereditary Leiomyomatosis and Renal Cell Cancer

– Tuberous sclerosis (TS): patients present with facial angiofibromas (adenoma sebaceum), shagreen patch, and periungual fibromas. [dermatologyadvisor.com]

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Proliferating Angioendotheliomatosis

patch) Cutaneous endometriosis Cutaneous meningioma (Heterotopic meningeal tissue, Rudimentary meningocele) Cutaneous myelofibrosis Cutaneous myxoma Cutis marmorata telangiectatica [doctors-hospitals-medical-cape-town-south-africa.blaauwberg.net]

patches, periungual fibromas, hypopigmented macules) 1/6-10,000 incidence Two genes involved: TSC1 (9q34) and TSC2 (16p13) Giant cell astrocytomas Renal angiomyolipomas [orthopaedicsone.com]

Chondroid lipoma Chordoma Classic Kaposi sarcoma Collagenous fibroma (Desmoplastic fibroblastoma) Composite hemangioendothelioma Connective tissue nevus (Collagenoma, Elastoma, Shagreen [doctors-hospitals-medical-cape-town-south-africa.blaauwberg.net]

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Vitiligo

patches, or angiofibromas. [pediatrics.aappublications.org]

[…] diagnosis with tuberous sclerosis might be trickier in case of ash-leaf hypopigmented spots (Fig 4A) without seizures or other usually later cutaneous symptoms, such as shagreen [pediatrics.aappublications.org]

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Familial Spontaneous Pneumothorax

patches (rough, elevated lesions commonly seen on the lower back) Hypomelanotic macular lesions, also referred to as ash leaf lesions (oval or ash leaf-shaped lesions with [thelamfoundation.org]

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Spontaneous Pneumothorax

patch ( Figure 3 ). [mdedge.com]

[…] lungs (lymphangioleiomyomatosis, causing pneumothorax or chylothorax), and the skin; skin lesions include facial angiofibromas ( Figure 1 ), ash-leaf spot ( Figure 2 ), and shagreen [mdedge.com]

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Palmoplantar Pustulosis

Patch,) Angiolymphoid Hyperplasia With Eosinophilia (24 %) ( Epithelioid Hemangioma, Histiocytoid Hemangioma, Inflammatory Angiomatous Nodule, Inflammatory Arteriovenous [gulfdoctor.net]

Acral Erythema (24 %) Takayasu Arteritis (24 %) ( Aortic Arch Syndrome, Pulseless Disease,) Pemphigus Vulgaris (24 %) Connective Tissue Nevus (24 %) ( Collagenoma, Elastoma, Shagreen [gulfdoctor.net]

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Woolly Hair Nevus

Classification : Subepidermal Connective tissue naevi Collagen naevi • Familial cutaneous collagenoma • Eruptive collagenoma • Shagreen patch • Other collagenomas Elastic [slideshare.net]

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Generalized Clonic or Tonic-Clonic Seizures

patches) Neurocutaneous disorders (eg, neurofibromatosis, tuberous sclerosis) *Spontaneous venous pulsations are absent in all patients with increased intracranial pressure [merckmanuals.com]

[…] alcohol or sedatives) Certain metabolic disorders (eg, hypocalcemia, hypomagnesemia) Skin lesions (eg, axillary freckling or café-au-lait spots, hypomelanotic skin macules, shagreen [merckmanuals.com]

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Cerebral Neoplasm

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Breast Hamartoma

patches: seen in 20-30% of patients periungual fibroma (Koenen tumors): 20% of patients Treatment and prognosis Treatment of seizures is essential and depending on the degree [radiopaedia.org]

patches, ungula fibromas, cortical dysplasias, and increased risk of several types of tumors, including astrocytoma, cardiac rhabdomyoma, and angiomyolipomas [19,21]. [mdpi.com]

[…] facial angiofibromas (Pringle nodules or adenoma sebaceum); seen in 75% of patients fibrous plaques of the forehead (15-20%) confetti lesions: variant of leukoderma spots shagreen [radiopaedia.org]

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Tumor Lysis Syndrome

Salient dermatologic findings of TSC are hypopigmented macules (ash-leaf spots), shagreen patches, periungual fibromas, and adenoma sebaceum. [emedicine.medscape.com]

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Helsmoortel-van der Aa Syndrome

Cutaneous manifestations are facial angiofibromas (adenoma sebaceum), Shagreen patches, hypopigmented macules, ash leaf spots, café-au-lait spots, facial hypoplasia and periungual [japi.org]

Shagreen patches, a form of collagenoma, may be seen in the lumbosacral region in half of patients. [omicsonline.org]

Fibrous plaques on the forehead or in hairy skin may be regarded as a variant of the shagreen patch. [omicsonline.org]

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