Shagreen Patch Causes & Reasons

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Shagreen Patch Symptom Checker: Possible causes include Lymphangioleiomyomatosis. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.

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Possible Causes

Lymphangioleiomyomatosis

Besides facial angiofibromas and shagreen patches over the back, no other physical signs such as those referable to the respiratory system were noted. [nature.com]

patch Forehead plaque Retinal hamartoma Laboratory Findings Pulmonary function tests are used to assess the lung damage caused by lymphangiomyomatosis. [wikidoc.org]

Finally, signs consistent with TSC, such as facial angiofibromas, periungual fibromas, nail ridging and the shagreen patch, are seen in patients with TSC-LAM. [err.ersjournals.com]

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Tuberous Sclerosis

patches; and 14 lesions (12%), large shagreen patches. [ncbi.nlm.nih.gov]

Only 1 of 5 patients treated for shagreen patches showed improvement at 12 months. Treatment was well tolerated with no serious adverse events. [ncbi.nlm.nih.gov]

Diagnostic methods Diagnosis is based on presence of major (cortical dysplasias; subependymal nodules; SEGA; hypomelanotic macules ( 3, diameter 5 mm); shagreen patch; angiofibromas [orpha.net]

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Familial Cutaneous Collagenoma

Shagreen patches are most often associated with Tuberous sclerosis. [ozarkderm.com]

Shagreen patch: Shagreen patch is a collagenoma variant associated with tuberous sclerosis, a disease most commonly inherited in an autosomal dominant pattern. [emedicine.medscape.com]

FCC: Multiple, indurated cutaneous papulonodules that vary in size are located over the upper two thirds of the back Shagreen patch: Flesh-colored plaques of variable size [dermaamin.com]

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Subungual Fibroma

SHAGREEN PATCH- Leathery plaques of subepidermal fibrosis,usually situated on the trunk. 13. SHAGREEN PATCH. 14. [slideshare.net]

Other lesions which may be present (usually on the trunk) are shagreen patches (these are localized thickening of the skin with a rough surface) and ash-leaf patches (hypopigmented [mrcophth.com]

Shagreen Patch The shagreen patch is an area of thickened, elevated pebbly skin (like an orange peel) usually found on the lower back. It can be single or multiple. [tsalliance.org]

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Renal Fibroma

Shagreen patch was seen in the right lumbosacral region ( Fig. 1 b). [revistanefrologia.com]

Shagreen patch (connective tissue naevus). Cortical tuber. Subependymal nodule (SEN). Subependymal giant cell astrocytoma (SEGA). [patient.info]

patch Cerebral white matter migration lines Multiple retinal nodular hamartomas Gingival fibromas Cortical tuber Non-renal hamartoma Subependymal nodule Retinal achromatic [academic.oup.com]

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Subependymal Giant Cell Astrocytoma

Skin manifestations like shagreen patches were present in two, facial angiofibromas in three, periungal fibromas in two, hypopigmented macules in two and ash-leaf spot in [ncbi.nlm.nih.gov]

(J Child Neurol 1999;14:401) Major features Facial angiofibromas or forehead plaque Nontraumatic ungual or periungual fibroma Hypomelanotic macules (more than 3) Shagreen [pathologyoutlines.com]

Several facial and body hyperpigmented fibrous plaques and a posterior lumbar Shagreen patch were noted. 3. [hindawi.com]

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Third Trimester Pregnancy

Detailed examination of the skin and mucosa revealed Shagreen patches, nontraumatic subungual and gingival fibroma, all features of tuberous sclerosis complex. [degruyter.com]

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Angiomyolipoma

Shagreen patches (white arrows). C. Subungual fibromas in the hand (white arrows). D. Subungual fibromas in the feet (white arrows). [oatext.com]

Shagreen patch connective-tissue nevus composed of collagen, i.e. collagenoma.[11] Ash-leaf spots. Hypopigmented macules.[12] Lymphangioleiomyomatosis. SEGA. [librepathology.org]

patches) (3, 4). [ncbi.nlm.nih.gov]

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Zosteriform Lentiginosis

Patch,) Carney Complex (48 %) ( Lamb Syndrome, Name Syndrome,) Seborrheic Keratosis (48 %) ( Seborrheic Verruca, Senile Wart,) Grovers Disease (45 %) ( Benign Papular Acantholytic [gulfdoctor.net]

toxocariasis, tuberous sclerosis, Wyburn-Mason’s s. serpiginous snakelike lesions; larva migrans, lupus vulgaris, syphilis shagreen patch skin colored indurated plaque [dermadvocate.net]

Bathing Trunk Nevus, Congenital Nevomelanocytic Nevus, Garment Nevus, Giant Hairy Nevus, Nevus Pigmentosus Et Pilosus,) Connective Tissue Nevus (48 %) ( Collagenoma, Elastoma, Shagreen [gulfdoctor.net]

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Benign Cephalic Histiocytosis

Patch,) Differentials from Google. [gulfdoctor.net]

( Infantile Papular Acrodermatitis, Papular Acrodermatitis Of Childhood, Papulovesicular Acrolocated Syndrome,) Connective Tissue Nevus (57 %) ( Collagenoma, Elastoma, Shagreen [gulfdoctor.net]

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Hamartoma of the Central Nervous System

patches -Minimal to no risk of malignant transformation of skin lesions -Skin lesions tend to increase in size and number through puberty, and then tend to stabalize over [pedclerk.bsd.uchicago.edu]

Major features are cortical tubers, subependymal nodules, subependymal giant cell astrocytomas (SEGA), hypomelanotic skin macules, shagreen patches, retinal nodular hamartomas [neuropathology-web.org]

Salient dermatologic findings of TSC are hypopigmented macules (ash-leaf spots), shagreen patches, periungual fibromas, and adenoma sebaceum. [emedicine.medscape.com]

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Rhabdomyoma of the Myocardium

A shagreen patch was present in the right lower lumbar region. Patient was put on valproate. Patient became conscious and oriented over a span of 1 h. [mjdrdypu.org]

Finally, about the other lesions of TSC, we found hypomelanotic macules in all, facial angiofibroma in 45,1% and shagreen patches in only 19,3%. [bmccardiovascdisord.biomedcentral.com]

patch, facial angioma's, hypomelanotic macules and periungal fibromas. [mjdrdypu.org]

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Cystic Lung Disease

Patients with TSC usually present angiomyolipomas, angiofibromas, hypopigmented macules, shagreen patch, and/or periungual fibromas. [archbronconeumol.org]

patches (rough, elevated lesions commonly seen on the lower back) Hypomelanotic macular lesions, also referred to as ash leaf lesions (oval or ash leaf-shaped lesions with [thelamfoundation.org]

Angiofibromas (acne-like small reddish nodular lesions on the face, especially the nose and cheeks) Subungual fibromas (fibrous nodules arising around or beneath the nails) Shagreen's [thelamfoundation.org]

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Brain Neoplasm

patches, incr. incidence of subependymal astrocytomas hemangiomas in skin, mucosa, organs, bilat renal cell carcinoma, hemangioblastoma in retina, brain stem, and cerebellum [brainscape.com]

[…] in CNS and skin, angiofibromas, mitral regurgitation, ash-leaf spots, cardiac rhabdomyoma, (tuberous sclerosis, autosomal dOminant), MR, renal angiomyolipoma, seizures, shagreen [brainscape.com]

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Severe Idiopathic Pneumococcemia

patch (raised orange peel appearance) adenoma sebaceum (skin colored or pink lesion often present on face in late childhood to early adolescence) - which is a misnomer as [brainscape.com]

[…] rash on the back lasts 4-6 weeks nobody knows what causes it itchy The classic lesions are: - ash leaf macule (often present at birth, most easily seen with a wood's lamp) shagreen [brainscape.com]

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Hereditary Mucoepithelial Dysplasia

Shagreen patches can be seen in patients with: a. Multiple Hamartoma syndrome b. Hereditary hemorrhagic telangictasia c. Tuberous sclerosis * d. [fac.ksu.edu.sa]

/periungual fibromas, shagreen patches, ash-leaf spots, CNS findings (seizures, mental retardation), cardiac rhabdomyomas, and angiomyolipoma CNS findings associated with [studystack.com]

• Two other characteristic skin lesions are • connective tissue hamartomas –shagreen patches • ovoid areas of hypopigmentation -ashleaf spots. [slideshare.net]

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Familial Papillary Thyroid Carcinoma with Papillary Renal Cell Carcinoma

patches, and hypopigmented macules. [jmg.bmj.com]

[…] disease involving multiple tissues and organs. 34 The patients present with dermatological lesions such as facial angiofibromas (adenoma sebaceum), periungual fibromas, shagreen [jmg.bmj.com]

[…] dominant disease involving multiple tissues and organs.34 The patients present with dermatological lesions such as facial angiofibromas (adenoma sebaceum), periungual fibromas, shagreen [jmg.bmj.com]

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Carcinoma of the Breast

patch and elastic tissue nevus. [ncbi.nlm.nih.gov]

[…] skin tags”; when the reticular dermis is involved mostly, the abnormality may be of collagen, elastic tissue, acid mucopolysaccharides, or any combination of them, as in shagreen [ncbi.nlm.nih.gov]

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Hereditary Leiomyomatosis and Renal Cell Cancer

– Tuberous sclerosis (TS): patients present with facial angiofibromas (adenoma sebaceum), shagreen patch, and periungual fibromas. [dermatologyadvisor.com]

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Proliferating Angioendotheliomatosis

patch) Cutaneous endometriosis Cutaneous meningioma (Heterotopic meningeal tissue, Rudimentary meningocele) Cutaneous myelofibrosis Cutaneous myxoma Cutis marmorata telangiectatica [doctors-hospitals-medical-cape-town-south-africa.blaauwberg.net]

patches, periungual fibromas, hypopigmented macules) 1/6-10,000 incidence Two genes involved: TSC1 (9q34) and TSC2 (16p13) Giant cell astrocytomas Renal angiomyolipomas [orthopaedicsone.com]

Chondroid lipoma Chordoma Classic Kaposi sarcoma Collagenous fibroma (Desmoplastic fibroblastoma) Composite hemangioendothelioma Connective tissue nevus (Collagenoma, Elastoma, Shagreen [doctors-hospitals-medical-cape-town-south-africa.blaauwberg.net]

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Vitiligo

patches, or angiofibromas. [pediatrics.aappublications.org]

[…] diagnosis with tuberous sclerosis might be trickier in case of ash-leaf hypopigmented spots (Fig 4A) without seizures or other usually later cutaneous symptoms, such as shagreen [pediatrics.aappublications.org]

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Familial Spontaneous Pneumothorax

patches (rough, elevated lesions commonly seen on the lower back) Hypomelanotic macular lesions, also referred to as ash leaf lesions (oval or ash leaf-shaped lesions with [thelamfoundation.org]

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Spontaneous Pneumothorax

patch ( Figure 3 ). [mdedge.com]

[…] lungs (lymphangioleiomyomatosis, causing pneumothorax or chylothorax), and the skin; skin lesions include facial angiofibromas ( Figure 1 ), ash-leaf spot ( Figure 2 ), and shagreen [mdedge.com]

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Palmoplantar Pustulosis

Patch,) Angiolymphoid Hyperplasia With Eosinophilia (24 %) ( Epithelioid Hemangioma, Histiocytoid Hemangioma, Inflammatory Angiomatous Nodule, Inflammatory Arteriovenous [gulfdoctor.net]

Acral Erythema (24 %) Takayasu Arteritis (24 %) ( Aortic Arch Syndrome, Pulseless Disease,) Pemphigus Vulgaris (24 %) Connective Tissue Nevus (24 %) ( Collagenoma, Elastoma, Shagreen [gulfdoctor.net]

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Woolly Hair Nevus

Classification : Subepidermal Connective tissue naevi Collagen naevi • Familial cutaneous collagenoma • Eruptive collagenoma • Shagreen patch • Other collagenomas Elastic [slideshare.net]

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Generalized Clonic or Tonic-Clonic Seizures

patches) Neurocutaneous disorders (eg, neurofibromatosis, tuberous sclerosis) *Spontaneous venous pulsations are absent in all patients with increased intracranial pressure [msdmanuals.com]

[…] alcohol or sedatives) Certain metabolic disorders (eg, hypocalcemia, hypomagnesemia) Skin lesions (eg, axillary freckling or café-au-lait spots, hypomelanotic skin macules, shagreen [msdmanuals.com]

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Cerebral Neoplasm

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Breast Hamartoma

patches: seen in 20-30% of patients periungual fibroma (Koenen tumors): 20% of patients Treatment and prognosis Treatment of seizures is essential and depending on the degree [radiopaedia.org]

patches, ungula fibromas, cortical dysplasias, and increased risk of several types of tumors, including astrocytoma, cardiac rhabdomyoma, and angiomyolipomas [19,21]. [mdpi.com]

[…] facial angiofibromas (Pringle nodules or adenoma sebaceum); seen in 75% of patients fibrous plaques of the forehead (15-20%) confetti lesions: variant of leukoderma spots shagreen [radiopaedia.org]

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Tumor Lysis Syndrome

Salient dermatologic findings of TSC are hypopigmented macules (ash-leaf spots), shagreen patches, periungual fibromas, and adenoma sebaceum. [emedicine.medscape.com]

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Helsmoortel-van der Aa Syndrome

Cutaneous manifestations are facial angiofibromas (adenoma sebaceum), Shagreen patches, hypopigmented macules, ash leaf spots, café-au-lait spots, facial hypoplasia and periungual [japi.org]

Shagreen patches, a form of collagenoma, may be seen in the lumbosacral region in half of patients. [omicsonline.org]

Fibrous plaques on the forehead or in hairy skin may be regarded as a variant of the shagreen patch. [omicsonline.org]

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