Short QT Interval: Causes & Reasons

Possible Causes for Short QT Interval

The ECG shows: Bizarre-looking QRS complexes Very short QT interval J waves = notching of the terminal QRS, best seen in lead V1 Many thanks to Dr James Hayes, FACEM, for [web.archive.org]

Cardiovascular effects include prolonged PR interval, short QT interval, widened QRS complex, and bradycardia. [ncbi.nlm.nih.gov]

Primary Hyperparathyroidism

QT interval on the electrocardiogram 20. [f1000research.com]

Also, manifestations related to symptomatic hypercalcemia can be present; these include nausea, vomiting, constipation, polyuria, polydipsia, mental confusion, coma, and a short [f1000research.com]

Acidosis

Metabolic acidosis is primary reduction in bicarbonate (HCO 3 − ), typically with compensatory reduction in carbon dioxide partial pressure (P co 2 ); pH may be markedly low or slightly subnormal. Metabolic acidoses are categorized as high or normal anion gap based on the presence or absence of unmeasured anions in[…] [merckmanuals.com]

Short QT Syndrome Type 1

Conversely, little is known about the clinical implication of a short QT interval, and only anecdotal reports suggest that a short QT interval could be responsible for an [doi.org]

A short QT interval is the main component of the syndrome, but because of an abnormal relationship between the QT interval and the RR interval in SQTS patients, the short [dx.doi.org]

Only a few reports of persistently short QT interval have been published. [doi.org]

Torsade-De-Pointes Syndrome with Short Coupling Interval

The electrocardiogram (ECG) was characterized by normal QT intervals with short-coupled variant of torsade de pointes. [link.springer.com]

Gussak I, Brugada P, Brugada J, Wright RS, Kopecky SL, et al. (2000) Idiopathic short QT interval: a new clinical syndrome? [omicsonline.org]

Figure 2 shows a long QT interval and polymorphic ventricular tachycardia (torsades de pointes) that began after a long-short sequence [4]. [ipej.org]

Digitalis Toxicity

Abstract Significant digitalis toxicity, although uncommon, is a medical emergency. Recognition of the problem and good supportive care (eg, administration of activated charcoal and binding resins, correction of potassium levels, restoration of heart rhythm) are the cornerstones of treatment. If indicated,[…] [ncbi.nlm.nih.gov]

Idiopathic Hypercalcemia

J Appl Genet. 2017 Aug;58(3):349-353. doi: 10.1007/s13353-017-0397-2. Epub 2017 May 3. Pronicka E 1, 2, Ciara E 3, Halat P 3, Janiec A 4, Wójcik M 5, Rowińska E 4, Rokicki D 4, Płudowski P 5, Wojciechowska E 6, Wierzbicka A 5, Książyk JB 4, Jacoszek A 7, 8, Konrad M 9, Schlingmann KP 9, Litwin M 6. Author information 1[…] [ncbi.nlm.nih.gov]

Hypercalcemia of Malignancy

Abstract Parathyroid hormone-related protein (PTHrP) was originally discovered because of its role in humoral hypercalcemia of malignancy (HHM), a common metabolic complication of many types of cancer. In HHM, PTHrP is released into the circulation by malignant cells and cross reacts with parathyroid hormone (PTH)[…] [ncbi.nlm.nih.gov]

Respiratory Acidosis

Respiratory acidosis Synonym Hypercarbia Related Conditions Hypoxemia Metabolic acidosis Metabolic alkalosis Respiratory alkalosis 1. Description of the problem Respiratory acidosis is caused by relative hypoventilation. Major risk is associated hypoxemia. Clinical importance depends on context and severity, and rate of[…] [clinicaladvisor.com]

Metabolic Acidosis

Previous | Index | Next 5.2.1 Classification by Patho-physiological Mechanism A decrease in plasma bicarbonate can be caused by two mechanisms: A gain of strong acid A loss of base All causes of a metabolic acidosis must work by these mechanisms. The gain of strong acid may be endogenous (eg ketoacids from lipid[…] [anaesthesiamcq.com]

Long QT Syndrome 8

Sotalol did not prolong the QT interval in patients with short QT. [shortqtsyndrome.org]

[…] of CSQTS is an abnormally short QT interval. [crediblemeds.org]

[…] asymptomatic individuals with short QT intervals. [aerjournal.com]

Williams-Beuren Syndrome

Williams syndrome definition and facts* *Williams syndrome definition and facts medical author: Charles Patrick Davis, MD, PhD Williams syndrome is a disorder in development that usually results in learning problems, attention deficit disorder, anxiety, and phobias but affected individuals have outgoing personalities. Sings[…] [medicinenet.com]

SHORT Syndrome

Therefore, in order to get a reliable assessment of the QT interval in a patient suspected of having a short QT interval and possibly Short QT Syndrome every effort should [shortqtsyndrome.org]

BUT WHAT IS CONSIDERED A SHORT QT INTERVAL? [mdedge.com]

Jose Luis Merino, FESC Short QT syndrome is an inherited cardiac channelopathy characterised by an abnormally short QT interval and an increased risk of atrial and ventricular [escardio.org]

Long QT Syndrome 3

Loss-of-function mutations in the cardiac calcium channel underlie a new clinical entity characterized by ST-segment elevation, short QT intervals, and sudden cardiac death [emedicine.medscape.com]

The long cycle is the compensatory pause following that VPB, whereas the second short cycle is the coupling interval of the first beat of the tachycardia. [romanianjournalcardiology.ro]

QT interval. [16] Mutations in the genes GPD1-L [17] and SCN1B [18] have been identified in a few familial cases. [emedicine.medscape.com]

Vitamin D Toxicity

Hypercalcemia in ambulatory patients is occasionally caused by vitamin D toxicity. We report nine patients presenting to Columbia University Medical Center with hypercalcemia due to a supplement from the Dominican Republic containing massive amounts of vitamin D. Case histories and laboratory evaluation (calcium, PTH,[…] [ncbi.nlm.nih.gov]

Brugada Syndrome

Mutation in the KCNQ1 gene leading to the short QT-interval syndrome. Circulation. 2004 ; 109 : 2394–2397. [dx.doi.org]

Atrial fibrillation in the setting of familial short QT interval. Heart Rhythm 2004; 1: S165 (abstract). [escardio.org]

Neonatal Cardiac Arrhythmia

Bjerregaard P, Collier JL, Gussak I: Upper limits of QT/QTc intervals in the short QT syndrome. [karger.com]

Idiopathic short QT interval: a new clinical syndrome? Cardiology. 2000; 94(2):99-102. 2. [babymhospital.org]

Gussak I et al. (2000) Idiopathic short QT interval: a new clinical syndrome? Cardiology 94 : 99–102 32. [nature.com]

Andersen-Tawil Syndrome

Short QT syndromes are heart disorders characterized by idiopathic persistently and uniformly short QT interval on ECG in the absence of structural heart disease in affected [novusbio.com]

Short QT syndrome 3 (SQT3) [MIM:609622]: A heart disorder characterized by idiopathic persistently and uniformly short QT interval on ECG in the absence of structural heart [genecards.org]

Defects in KCNJ2 are the cause of short QT syndrome type 3 (SQT3). [mybiosource.com]

Short QT Syndrome

Atrial fibrillation in the setting of familial short QT interval. Heart Rhythm 2004; 1: S165 (abstract). [escardio.org]

[…] asymptomatic individuals with short QT intervals. [ncbi.nlm.nih.gov]

[…] fibrillation QT, ST and T-wave changes in SQTS Short QT interval, peaked T waves and short ST segments in two patients with SQTS 1. [litfl.com]

Digitalis

Digitalis L. Sormustinkukat Foxglove Digitalis, Den Virtuella Floran [DVF] Foodplants for Euphydryas aurinia, E. aurinia beckeri, E. maturna, Melitaea athalia, M. aurelia, Polymixis flavicincta 500x775 (~75Kb) USA: Near Bandera Mtn, (47°24'23N 121°33'51W), King Co., WA, 15.7.1999, Photo © Markku Savela 600x935 (~72Kb) USA:[…] [ftp.funet.fi]

Catecholaminergic Polymorphic Ventricular Tachycardia Type 4

QT intervals, and sudden cardiac death. [link.springer.com]

Pollevick GD, Cordeiro JM et al. (2007) Loss-of-function mutations in the cardiac calcium channel underlie a new clinical entity characterized by ST-segment elevation, short [link.springer.com]

Familial Atrial Fibrillation Type 12

Short QT syndrome. Cardiovasc Res. 2005 Aug 15;67(3):357-66. [ PMID: 15890322 ] [ Full text ] Viskin S. The QT interval: too long, too short or just right. [lifeinthefastlane.com]

Thus, atrial fibrillation is a part of the short QT syndrome. Short QT interval alone does not predispose to atrial fibrillation. [ipej.org]

Here we report a different KCNJ2 mutation (E299V) identified in a child with a remarkably short QT interval and atrial fibrillation (AF). [pnas.org]

KCNQ3-Related Disorder

Mutation in the KCNQ1 gene leading to the short QT-interval syndrome. Circulation. 2004;109:2394–7. [ncbi.nlm.nih.gov]

Paroxysmal Ventricular Fibrillation Type 1

Idiopathic short QT interval: a new clinical syndrome? Circulation. 2000;94:99-102. [e-arrhythmia.org]

Case subjects were excluded if they had a QT interval corrected for heart rate (QTc) of less than 340 msec (short QT interval) or more than 440 msec (long QT interval) at [nejm.org]

Loss-of-Function Mutations in the Cardiac Calcium Channel Underlie a New Clinical Entity Characterized by ST-Segment Elevation, Short QT Intervals, and Sudden Cardiac Death [bcs.com]

Familial Atrial Fibrillation 3

QT interval and peaked T waves …suggestive of congenital short QT syndrome (SQTS) Q3. [lifeinthefastlane.com]

Thus, atrial fibrillation is a part of the short QT syndrome. Short QT interval alone does not predispose to atrial fibrillation. [ipej.org]

Here we report a different KCNJ2 mutation (E299V) identified in a child with a remarkably short QT interval and atrial fibrillation (AF). [pnas.org]

Torsades De Pointes

View this short 9 minute video on QT intervals and Torsades de Pointes. [aliem.com]

"Twisting of the points," a form of ventricular tachycardia nearly always due to medications and characterized by a long QT interval and a "short-long-short" sequence in the [medical-dictionary.thefreedictionary.com]

The following beat (second beat: long) has a longer QT interval. [en.ecgpedia.org]

Familial Atrial Fibrillation 6

Thus, atrial fibrillation is a part of the short QT syndrome. Short QT interval alone does not predispose to atrial fibrillation. [ipej.org]

QT syndrome and atrial fibrillation caused by mutation in KCNH2, J Cardiovasc Electrophysiol, 2005, vol. 16 (pg. 394 - 6 ) 33 Idiopathic short QT interval: a new clinical [academic.oup.com]

Short QT syndrome In 2003, Gaita and colleagues identified 2 families with an inherited arrhythmia syndrome characterised by shortening of the QT interval. 26 Subsequent genetic [aups.org.au]

Long QT Syndrome 6

The main ECG changes are very short QTc ( Short QT syndrome may be suggested by the presence of: Lone atrial fibrillation in young adults Family member with a short QT interval [lifeinthefastlane.com]

雑誌名 Hum Muta 30 ページ : 557-563 関連する報告書査読あり [雑誌論文] A novel KCNH2 mutation as a modifier for short QT interval 2009 著者名/発表者名 Itoh H, Sakaguchi T, Ashihara T, Ding G W, Nagaoka [kaken.nii.ac.jp]

Suspecting acquired long QT syndrome, the pediatrician obtained an ECG, which demonstrated a prolonged corrected QT interval (QTc ˜0.5 sec ½ ). [pedsinreview.aappublications.org]

Diffuse Intraventricular Block

QT interval Increased u-wave amplitude Prolonged PR-interval Sinus bradycardia ECG changes typical for digoxin intoxication are: Bradyarrhythmias: AV block. [en.ecgpedia.org]

Hypercalcemia During sinus rhythm with normal rates the QT interval is short (Fig. 94-29a bottom). [rjmatthewsmd.com]

[…] typical for digoxin use (digoxin = Lanoxin) are: Oddly shaped ST-depression with 'scooped out' appearance of the ST segment (see figure) Flat, negative or biphasic T wave Short [en.ecgpedia.org]

Paroxysmal Ventricular Fibrillation

Short QTc intervals were more commonly seen during bradycardia. However, the correlation between short QT and a history of VF was independent of heart rate. [ncbi.nlm.nih.gov]

Patients presenting with signs of early repolarization, Brugada Type 1 or 2 ECG, prolonged corrected QT interval (QTc >480 ms), short-QT interval (QTc <320 ms), Wolff–Parkinson–White [academic.oup.com]

The QT segment can be relatively short, but not short enough to meet the short QT syndrome criteria. The Tpeak-Tend interval, a marker of arrhythmic risk, is normal. [symptoma.com]