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65 Possible Causes for Shortening of the Fifth Metacarpal

  • Lelis Syndrome

    Patients present shortened fourth and fifth metacarpals with excessive separation between their distal ends, resulting in marked ulnar deviation of the little finger and an[mendelian.co] metacarpals with no other associated abnomalities.[mendelian.co] METACARPAL 4-5 FUSION; MF4 Syndactyly type 8 is a rare, genetic, non-syndromic, congenital limb malformation characterized by unilateral or bilateral fusion of the fourth and fifth[mendelian.co]

  • SHORT Syndrome

    Shortening of the fourth/fifth metacarpals and less commonly metatarsals is seen in a variety of apparently disparate conditions.[radiopaedia.org]

  • Campomelic Dysplasia

    Moderate shortening of second through fifth metacarpals with severe shortening of first metacarpal ( Fig. 123A2 ) and bilateral clubfeet ( Fig. 123B1 ) with severe metatarsus[radiologykey.com]

  • Familial Short Stature

    FSS patients without clinical fifth metacarpal bone shortening had shortened third and fourth metacarpal bones, fifth proximal phalanx, and fifth distal phalanx.[ncbi.nlm.nih.gov] Abstract Fifth metacarpal bone shortening (brachymetacarpia V) was recently described to be highly prevalent in children with familial short stature (FSS).[link.springer.com] Radiologic anthropometry revealed that FSS patients with clinically shortened fifth metacarpal bone frequently had shortened first metacarpal bones, second and third proximal[ncbi.nlm.nih.gov]

  • Crossed Polysyndactyly

    Additional symptoms may involve shortening of fused fourth and fifth metacarpals, ulnar deviation of fingers from second to fifth, interdigital cleft between third and fourth[nature.com] There are shortened fourth and fifth metacarpals with excessive separation between their distal ends, and inability to bring the affected fingers in parallel to other fingers[nature.com] ) The hallmark of this type is the fusion of fourth and fifth metacarpals ( Figure 2 ).[nature.com]

  • Thyrotropin

    Ventriculomegaly and bilateral shortening of the fifth metacarpal bones and the middle phalanges of the fifth fingers might be characteristic features of NAH because of an[ncbi.nlm.nih.gov] In addition to hyperthyroidism, ventriculomegaly and bilateral shortening of the fifth metacarpal bones and the middle phalanges of the fifth fingers were consistently found[ncbi.nlm.nih.gov] In addition, the shortening of the middle phalanges of the fifth fingers has never been previously described, expanding the phenotypic spectrum of the disease.[ncbi.nlm.nih.gov]

  • Pseudohypoparathyroidism Type 1A

    […] fourth and fifth metacarpals, rounded facies, and often mild intellectual deficiency.[en.wikipedia.org] Albright hereditary osteodystrophy the clinical presentation of shortened fourth/fifth metacarpals, short stature, mild mental ******ation and round facies.[forums.studentdoctor.net] There was mild shortening of the fourth and fifth metacarpals (Fig) . He was diagnosed as having PHP with AHO features, and received calcitriol and calcium supplement.[hkmj.org]

  • Syndactyly

    Additional symptoms may involve shortening of fused fourth and fifth metacarpals, ulnar deviation of fingers from second to fifth, interdigital cleft between third and fourth[nature.com] There are shortened fourth and fifth metacarpals with excessive separation between their distal ends, and inability to bring the affected fingers in parallel to other fingers[nature.com] ) The hallmark of this type is the fusion of fourth and fifth metacarpals ( Figure 2 ).[nature.com]

  • Geleophysic Dysplasia 2

    Besides short metacarpals and phalanges, internal notch of the second metacarpal, and external notch of the fifth metacarpal, other consistent features were shortened fourth[jmg.bmj.com] […] and fifth metacarpals and markedly delayed bone age.[jmg.bmj.com]

  • Autosomal Dominant Larsen Syndrome

    Moderate shortening of second through fifth metacarpals with severe shortening of first metacarpal ( Fig. 123A2 ) and bilateral clubfeet ( Fig. 123B1 ) with severe metatarsus[radiologykey.com]

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