Possible Causes for Sialorrhea Amyotrophic Lateral Sclerosis A review of options for treating sialorrhea in amyotrophic lateral sclerosis. Respir Care. 2015 Mar. 60 (3):446-54. [Medline]. [emedicine.com] Sialorrhea Sialorrhea (drooling), the unintentional loss of saliva from the mouth, occurs in up to 25% of patients with motor neuron disease and affects almost all patients [emedicine.com] Evidence regarding secondary symptoms like spasticity, muscle cramps or sialorrhea remains generally scarce, but some new insights will also be discussed. [ncbi.nlm.nih.gov] Carbamate Poisoning Atropine administration was an effective therapeutic approach for treating signs and symptoms, which included sialorrhea (p=0.0006), nausea (p=0. 0029) and emesis (p lt0.0001 [scielo.br] Rev Gaúcha Enferm. 2009; 30(4):648-55.It should be highlighted the appearance of bronchorrhea, sialorrhea, miosis, diarrhea, muscular fasciculation, seizures and cyanosis, [scielo.br] A detailed analysis of the therapeutic conduct administered to the 70 patients who formed our sample showed that atropine was effective in treating sialorrhea (p=0.0006), [scielo.br] Scorpion Sting Serious symptoms, most common among children, include Restlessness Muscle spasms Abnormal and random head, neck, and eye movements Anxiety and agitation Sialorrhea and diaphoresis [msdmanuals.com] Parkinson Disease Since there is insufficient evidence of glycopyrrolate for the treatment of sialorrhea exceeding 1 week, the practice implication is that it is possibly useful. [ncbi.nlm.nih.gov] […] of selected nonmotor symptoms of Parkinson disease, including rapid eye movement sleep behavior disorder, cognitive impairment, depression, orthostatic hypotension, and sialorrhea [doi.org] […] clozapine for the treatment of psychosis, rivastigmine for the treatment of dementia, and botulinum toxin A (BTX-A) and BTX-B as well as glycopyrrolate for the treatment of sialorrhea [ncbi.nlm.nih.gov] Aromatic L-Amino Acid Decarboxylase Deficiency Drooling Dribbling, Sialorrhea Habitual flow of saliva out of the mouth. [rarediseases.oscar.ncsu.edu] […] features of this condition include a combination of dopamine, noradrenaline, and serotonin deficiencies, and a patient may present with hypotonia, oculogyric crises, sweating, hypersalivation [semanticscholar.org] Clinical Presentation: symptoms may include temperature instability, ptosis of the eyelids, hypersalivation, distal chorea, swallowing difficulties, drowsiness, irritability [ndrf.org] Stomatitis […] an inflammation of the oral cavity, accompanied by the formation of a pseudomembrane. stomatitis, mercurial, n an oral manifestation of mercury poisoning, consisting of hypersalivation [medical-dictionary.thefreedictionary.com] Progressive Bulbar Paralysis Over time, virtually all patients with progressive bulbar palsy will develop sialorrhea that occurs as a result of severe dysphagia. [symptoma.com] Verma A and Steele J (2006) Botulinum toxin improves sialorrhea and quality of living in bulbar amyotrophic lateral sclerosis. Muscle Nerve 34 : 235–237 57. [nature.com] Wilson Disease Initially, the patient presented with akathisia, sialorrhea, oromandibular dystonia (occasionally grimacing) and slight dysarthria. [ncbi.nlm.nih.gov] Drooling, or sialorrhea, is also an early feature of WD and is seen at the initial examination in up to 21% of neurologic cases (23). [atm.amegroups.com] Rhododendron Poisoning […] of dizziness, blurred vision, diplopia, nausea, vomiting, vertigo, headache, sweating/excessive perspiration, extremity paresthesia, impaired consciousness, convulsion, hypersalivation [pubs.rsc.org] Tabun Poisoning Atropine sulfate blocks the muscarinic effects of acetylcholine that cause bronchorrhoea, hypersalivation, bronchoconstriction and bradycardia, thereby reducing these effects [emro.who.int] Malathion Poisoning In addition, the heart rate increased and hypersalivation was improved after the initiation of HDF. For aspiration-related pneumonia, sulbactam/ampicillin was used. [jintensivecare.biomedcentral.com] On the third hospital day, OP symptoms were exacerbated, with muscarinic manifestations including bradycardia and hypersalivation and decreased plasma cholinesterase activity [jintensivecare.biomedcentral.com] Clinical manifestations caused by organophosphates include hypersalivation, abdominal pain, nausea, vomiting, diarrhea, muscle fasciculations, bradycardia, and hypotension [jintensivecare.biomedcentral.com] Phencyclidine Intoxication Profuse diaphoresis, hypersalivation, bronchospasm, and urinary retention occurred in less than 5%. [ncbi.nlm.nih.gov] Hypersalivation and lacrimation may occur. Patients may abruptly swing between quiet catatonia and loud or agitated behavior. [accessmedicine.mhmedical.com] Parathion Poisoning After his hospitalization on his third day of poisoning, the patient was comatose, had a tight myosis and a diffuse tremor hypersalivation. [toxicology.imedpub.com] Botulism Randomized double-blind study of botulinum toxin type B for sialorrhea in ALS patients. Muscle Nerve. 2009 Feb. 39(2):137-43. [Medline]. [emedicine.medscape.com] Botulinum toxin type A on oral health in treating sialorrhea in children with cerebral palsy: a randomized, double-blind, placebo-controlled study. [emedicine.medscape.com] Treatment of sialorrhea in children with cerebral palsy: a double-blind placebo controlled trial. Clin Neurol Neurosurg. 2009 Jan. 111(1):79-82. [Medline]. [emedicine.medscape.com] Rabies The diagnosis is easy when a non-immunised patient presents with hydrophobia and hypersalivation after a bite by a known rabid animal but more difficult when a patient presents [ncbi.nlm.nih.gov] Symptoms As the disease progresses, neurological symptoms appear and may include: Insomnia Anxiety Confusion Slight or partial paralysis Excitation Hallucinations Agitation Hypersalivation [rabies.emedtv.com] As the disease progresses, more specific symptoms appear and may include insomnia, anxiety, confusion, slight or partial paralysis, excitation, hallucinations, agitation, hypersalivation [cdc.gov] Mercury Poisoning Gastrointestinal symptoms include a metallic taste, gingivostomatitis, nausea and hypersalivation. [ncbi.nlm.nih.gov] GI effects seen include gingivostomatitis, hypersalivation (ptyalism), non-specific abdominal pain, and nausea. A metallic taste is sometimes reported. [calpoison.org] Most of them showed hyperkinesis, hypersalivation, seizures, and strabismus [ 6, 12 ]. [doi.org] Cholinergic Crisis Features suggestive of a cholinergic crisis (too much medication) include muscle fasciculation, pallor, sweating, hypersalivation and small pupils. [patient.info] […] hyperstimulation by excess acetylcholine, eventually leading to death. 4 Symptoms of OP poisoning include, but are not limited to: miosis, sustained muscle contraction, twitching, hypersalivation [ncbi.nlm.nih.gov] Acrodynia With battery ingestion, one would expect signs of inorganic mercury exposure, such as hypersalivation and vomiting, rather than signs of organic mercury poisoning. [emedicine.com] Familial Dysautonomia Symptoms include speech and movement problems, anterior sialorrhea (drooling) due to hypersalivation as a consequence of poor oropharyngeal coordination; dysphagia and aspiration [ncbi.nlm.nih.gov] Botulinum neurotoxin may help to treat sialorrhea. Prognosis for FD patients has significantly improved over the past decades. [symptoma.com] These include orthostatic hypotension, sialorrhea (excessive salivation), gastrointestinal (GI) motility, bladder dysfunction, hypolacrimation or alacrima, mydriasis, and [journals.lww.com] Esophageal Obstruction Elderly patients are at especially at risk because they often have few teeth. [1] Odynophagia Partial obstruction of the esophagus can cause odynophagia. [1] Sialorrhea Sialorrhea [explainmedicine.com] Denture Problems Excessive vertical dimension may result in patients showing too much teeth, TMJ pain, muscle pain, difficulty swallowing, gagging, clicking of the dentures, sialorrhea (hypersalivation [dentaltown.com] […] adjust until patient comfortable) Denture vertical dimension occlusion Excessive VDO – Show too much teeth, TMJ pain, muscle pain, hard to swallow or gag, dentures click, hypersalivation [bauersmiles.com] (hypersalivation), and discomfort while chewing. [dentaltown.com] Facial Palsy […] when smiling, inability to close the right eye and to raise the right eyebrow, intense painful symptoms on the right side of the face, difficult in chewing and talking, and sialorrhea [ncbi.nlm.nih.gov] Pseudobulbar Palsy Verma A and Steele J (2006) Botulinum toxin improves sialorrhea and quality of living in bulbar amyotrophic lateral sclerosis. Muscle Nerve 34 : 235–237 57. [nature.com] Conditions mentioned include: hemiparesis; pseudo-bulbar palsy; cerebral vascular catastrophes; dysarthria; emotional over-reaction; hypersalivation; and arterial hypertension [archives.collections.ed.ac.uk] Aphthous Stomatitis They were associated with dysphagia and sialorrhea. Spontaneous healing occurred after 10 to 15 days. [jaad.org] Acrodynia (Pink disease): Oral and perioral ulceration, hypersalivation, gingivitis and early tooth loss are features of acrodynia caused by mercury poisoning, now rarely [stmina-monastery.org] Stroke OBJECTIVE: ed to investigate the association between blood pressure and acute phase stroke lethality in a Brazilian intensive care unit. METHODS: This was an observational, prospective cohort study of hemorrhagic and ischemic stroke intensive care patients. The primary outcome was all-cause mortality during the[…] [ncbi.nlm.nih.gov] Iodine Poisoning Manifestations of acute poisoning include abdominal pain, nausea, vomiting, hypersalivation, conjunctivitis, and collapse. [forum.marksdailyapple.com] Chronic manifestations include hypersalivation, fever, acute rhinitis, swelling and tenderness of the salivary glands, and dermatitis and stomatitis in hypersensitive individuals [forum.marksdailyapple.com] Foreign Body in the Esophagus Patients with complete obstruction of the esophagus hypersalivate and are unable to swallow oral secretions. [merckmanuals.com] The main presenting symptom is acute dysphagia; patients with complete obstruction of the esophagus hypersalivate and are unable to swallow oral secretions. [merckmanuals.com] Peritonsillar Abscess […] by Sue Pondrom • July 1, 2007 SAN DIEGO-A peritonsillar abscess (PTA) is an infection typically occurring in the potential space later to the tonsil. Although, in theory, it should not occur after tonsillectomy, there have been reported cases suggesting that PTA may be due to tonsillar remnants or minor salivary[…] [enttoday.org] Organophosphate Insecticide Antagonists The most frequent signs were meiosis, change in mental status, hypersalivation and fasciculations. Ten patients (21.2%) required mechanical ventilation. [ncbi.nlm.nih.gov] The most frequent clinical signs were meiosis, change in mental status, hypersalivation, agitation and fasciculations (Table 2 ). [ccforum.biomedcentral.com] The physical examination of the boy showed pinpoint pupils (2 mm diameter), hypersalivation and lacrimation. He was responsive to pain, but had slurred speech. [intjem.springeropen.com] Cicuta Maculata Poisoning Cicuta maculata. Synonym: Cicuta douglasii. (Water Hemlock) Apiaceae (Parsley Family) Montane. Wet areas. Summer. Haviland Lake Trail, June 28, 2004. Water Hemlock, found in continually wet areas, such as, lake shores, swamps, and roadside ditches, is highly poisonous, as is its very close, difficult to distinguish[…] [swcoloradowildflowers.com]
