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59 Possible Causes for Single Thumb Crease

  • Odonto Tricho Ungual Digito Palmar Syndrome

    […] transverse palmar creases first metacarpal hypoplasia prominent interdigital folds single thumb creases Head And Neck Face: prognathism Head And Neck Mouth: thick, coarse[malacards.org] ; Clinodactyly; Camptodactyly; Syndactyly; Single transverse palmar crease ; Persistent fetal fingertip pads; [Feet]; Broad halluces SKIN, NAILS, HAIR: [Skin]; Facial wrinkling[findzebra.com] […] trichodystrophy straw-like fragile hair irregular diameter of hair shaft with hypopigmentation and tendency to fracture (light microscopy) Skeletal Hands: brachydactyly single[malacards.org]

  • Gorlin-Chaudhry-Moss Syndrome

    Anomalies of the extremities (hypoplastic distal phalanges, small/aplastic nails, cutaneous syndactyly , absent flexion crease of the thumbs, single transverse palmar creases[rarediseases.info.nih.gov] Extremity anomalies (hypoplastic distal phalanges, small/aplastic nails, cutaneous syndactyly, absent flexion crease of the thumbs, single transverse palmar creases), umbilical[wiki.romse.org] Anomalies of the extremities (hypoplastic distal phalanges, small/aplastic nails, cutaneous syndactyly, absent flexion crease of the thumbs, single transverse palmar creases[malacards.org]

  • Trigonocephaly

    , bilateral single palmar creases, left talipes equinovarus, eventration of right hemidiaphragm, and bilateral inguinal hernia.[ncbi.nlm.nih.gov] […] basis of metopic craniosynostosis, upslanting palpebral fissures, high arched palate, redundant skin folds at the back of the neck, ventricular septal defect, broad flat thumbs[ncbi.nlm.nih.gov]

  • Ring Chromosome 13

    She had somewhat short second and fifth fingers, with a single crease on the right fifth finger and normal thumbs.[ncbi.nlm.nih.gov]

  • Dursun Syndrome

    Facial dysmorphism with hypertelorism, a broad nasal bridge and a high-arched palate, malformations of the hand with long fingers, proximally placed thumbs and a single palmar[symptoma.com] crease, and pectus carinatum have been reported.[symptoma.com]

  • Trisomy 4p

    […] umbilical artery, multicystic dysplastic left kidney, sacral dimple, anterior displacement of anus, simian creases, abnormal thumb (congenital clasped thumb), overlapping[ncbi.nlm.nih.gov] […] of the nose, large and low set ears, macroglossia, thin upper lip, double outlet right ventricle, atria/ventricular septal defect, cleft mitral valve, pulmonary stenosis, single[ncbi.nlm.nih.gov]

  • Fragile X Syndrome

    , a single palmar crease, and pes planus; clubfeet may be present at birth Pectus excavatum and scoliosis are frequent findings Genitals: Macroorchidism is nearly universal[emedicine.medscape.com] […] protrude Eyes: Strabismus is frequent; occasionally, nystagmus, astigmatism, and ptosis are present Hands and feet: hyperextensible finger joints, hand calluses, double-jointed thumbs[emedicine.medscape.com]

  • Warsaw Breakage Syndrome

    Small fibulae Others Abnormal skin pigmentation Single palmar crease Bloom syndrome Cornelia de Lange syndrome Fanconi anemia Nijmegen breakage syndrome Roberts syndrome[en.wikipedia.org] […] hypoplasia Cardiac features Ventricular septal defect Tetralogy of Fallot Sketelal features Clinodactyly of the fifth fingers Syndactyly of the second and third toes Small thumbs[en.wikipedia.org]

  • Saethre-Chotzen Syndrome

    Associated hands and feet malformations consist of bilateral single transverse palmar creases, syndactyly, broad thumbs, brachydactyly, hallux valgus, triphalangeal thumb,[symptoma.com] […] and/or a broad hallux (big toe) with a valgus deformity (outward angulation of the distal segment of a bone/joint) Hands have a single palmer flexion crease Unevenly positioned[en.wikipedia.org] […] forehead to appear tall and wide Webbing (syndactyly) between the second and third finger and between the second and third toes Short fingers and toes (brachydactyly) Broad thumb[en.wikipedia.org]

  • Smith Lemli Opitz Syndrome

    Abnormalities in limb development are common in SLOS patients and include short thumbs, postaxial polydactyly, and single palmar creases.[themedicalbiochemistrypage.org] These include short thumbs, single palmar creases, postaxial polydactyly and soft-tissue syndactyly of the second and third toes.[doi.org] Cleft palate or bifid uvula is also common. ( e) Limb anomalies include short proximally placed thumbs, single palmar creases, clinodactyly, and postaxial polydactyly. ( f[doi.org]

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