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3,445 Possible Causes for Single Transverse Palmar Crease, Sleep Apnea, Wide Space Between the First and Second Toe

  • Down Syndrome

    transverse palmar crease, and short fifth finger with clinodactyly.[dx.doi.org] Obstructive sleep apnea (OSA) is more common in children with Down syndrome, affecting up to 60% of patients, and may persist in up to 50% of patients after adenotonsillectomy[ncbi.nlm.nih.gov] spacing, often with a deep plantar groove between the first and second toes.[dx.doi.org]

  • Rubinstein-Taybi Syndrome

    transverse palmar crease 0000954 Spina bifida occulta 0003298 Sporadic No previous family history 0003745 Stereotypy Repetitive movements Repetitive or self-injurious behavior[rarediseases.info.nih.gov] Sleep apnea.[ncbi.nlm.nih.gov] Self-mutilation Deliberate self-harm Self mutilation [ more ] 0000742 Shawl scrotum 0000049 Short attention span Poor attention span Problem paying attention [ more ] 0000736 Single[rarediseases.info.nih.gov]

    Missing: Wide Space Between the First and Second Toe
  • Kaufman Oculocerebrofacial Syndrome

    transverse palmar crease 0000954 Sparse and thin eyebrow Thin, sparse eyebrows 0000535 Ventricular septal defect Hole in heart wall separating two lower heart chambers 0001629[rarediseases.info.nih.gov] , see Obstructive sleep apnea obstructive disease of the pulmonary veins , see Pulmonary veno-occlusive disease Obstructive sleep apnea obstructive sleep apnea syndrome ,[herenciageneticayenfermedad.blogspot.com] transverse palmar crease Feeding difficulties in infancy Narrow forehead Brachydactyly Hypoplasia of the corpus callosum Craniosynostosis Constipation Hypermetropia Coloboma[mendelian.co]

    Missing: Wide Space Between the First and Second Toe
  • Coffin-Lowry Syndrome

    transverse palmar crease 0000954 Sporadic No previous family history 0003745 Telecanthus Corners of eye widely separated 0000506 Thick eyebrow Bushy eyebrows Dense eyebrow[rarediseases.info.nih.gov] We reported here a patient with the Coffin-Lowry syndrome associated with obstructive sleep apnea syndrome (OSAS).[ncbi.nlm.nih.gov] apnea syndrome.[ncbi.nlm.nih.gov]

    Missing: Wide Space Between the First and Second Toe
  • Ring Chromosome 10

    Their common features were mental and growth retardation, low birth weight, microcephaly, stubby nose, hypertelorism, strabismus, wide set nipples, single transverse palmar[ncbi.nlm.nih.gov] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] The main features are low birth weight, microcephaly, stubby nose with a prominent nasal bridge, hypertelorism, strabismus, wide-set nipples, single transverse palmar creases[malacards.org]

    Missing: Sleep Apnea
  • Stuve-Wiedemann Syndrome

    transverse palmar crease 0000954 Square face Square facial shape 0000321 Talipes 0001883 Talipes valgus 0004684 Thin ribs Slender ribs 0000883 Thin skin 0000963 Tibial bowing[rarediseases.info.nih.gov] Some infants with STWS may develop episodes where they repeatedly stop breathing during sleep (sleep apnea). Feeding and swallowing difficulties may also occur.[rarediseases.org] […] palpebral fissure Short opening between the eyelids 0012745 Short phalanx of finger Short finger bones 0009803 Short tibia Short shinbone Short skankbone [ more ] 0005736 Single[rarediseases.info.nih.gov]

    Missing: Wide Space Between the First and Second Toe
  • Atelosteogenesis Type 2

    transverse palmar creases.[documents.tips] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] […] or commonly referred to as Sleep Apnea. 18. frequent respiratory infections 19. frequent ear infections. 20. connective tissue disorder 21. dislocation of the shoulders 22[tawnymullins77.blogspot.com]

  • Seckel Syndrome

    transverse palmar crease 0000954 Sloping forehead Inclined forehead Receding forehead [ more ] 0000340 Small anterior fontanelle 0000237 Small for gestational age Birth weight[rarediseases.info.nih.gov] Wide space between first and second toes Wide-spaced big toe Widely spaced 1st-2nd toes Widely spaced first and second toes Widened gap 1st-2nd toes Widened gap first and[rarediseases.info.nih.gov] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

    Missing: Sleep Apnea
  • Postaxial Oligodactyly, Tetramelic

    transverse palmar crease 32 HP:0000954 9 radial bowing 32 HP:0002986 10 postaxial oligodactyly 32 HP:0006210 11 partial-complete absence of 5th phalanges 32 HP:0006209 12[malacards.org] apnea Cone-shaped epiphysis Large hands Dysmenorrhea Palmoplantar keratoderma Widely spaced teeth Cerebral palsy Hoarse voice Acanthosis nigricans Thickened skin Pituitary[mendelian.co] transverse palmar crease Radial deviation of finger Broad hallux Cleft upper lip Gastrointestinal dysmotility Postnatal macrocephaly Microtia, first degree Branchial fistula[mendelian.co]

    Missing: Wide Space Between the First and Second Toe
  • Gorlin-Chaudhry-Moss Syndrome

    Anomalies of the extremities (hypoplastic distal phalanges, small/aplastic nails, cutaneous syndactyly, absent flexion crease of the thumbs, single transverse palmar creases[rarediseases.info.nih.gov] .: Rubinstein- Taybi Syndrome Table 1: Characteristic features of patient suffering from RSTS Features Orthopedic Eye Cardiac Dental Tumors Skin Sleep apnea Characterstic[zdoc.site] apnea Glaucoma type 1C Glaucoma congenital Glaucoma Ectopia Microspherophakia Stiff joints and Short stature syndrome Glaucoma hereditary Glaucoma hereditary adult type 1A[personalizedcause.com]

    Missing: Wide Space Between the First and Second Toe

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