Possible Causes for skeletal muscle weakness Muscular Dystrophy From Wikidata Jump to navigation Jump to search myopathy characterized by progressive skeletal muscle weakness degeneration edit English muscular dystrophy myopathy characterized [wikidata.org] […] by progressive skeletal muscle weakness degeneration MD Muscular dystrophy, MD Statements Identifiers Sitelinks Wikipedia (33 entries) edit Wikibooks (0 entries) edit Wikiquote [wikidata.org] Autosomal Recessive Centronuclear Myopathy muscle weakness. [invitae.com] […] characterized by muscle weakness (myopathy) and wasting (atrophy) in the skeletal muscles, which are the muscles used for movement. [icdlist.com] Centronuclear Myopathy is a condition in which there is a weakness in the muscles or atrophy of skeletal muscles. [wikiexclusive.com] Glycogen Storage Disease Type 5 Glycogen storage disease type V (GSD V) is an inherited disorder of glycogen metabolism that affects the skeletal muscle. [genedx.com] Three patients were wheelchair dependent due to skeletal muscle involvement (signs of permanent muscle weakness with atrophy). [link.springer.com] […] features Pain: Legs Arms Fatigue Cramps: Proximal muscles Muscle size Atrophy: Proportionate to weakness May be mild calf hypertrophy Tendon reflexes: Reduced in proportion [neuromuscular.wustl.edu] Barth Syndrome muscle weakness, or family history indicating an X-linked pattern of inheritance. [ncbi.nlm.nih.gov] Barth syndrome should be considered when boys present with cardiomyopathy, especially when associated with increased left ventricular trabeculations, neutropenia, skeletal [ncbi.nlm.nih.gov] Congenital Myopathy with Excess of Thin Filaments To date no therapy exists to treat muscle weakness in nemaline myopathy. [research.vu.nl] […] delay; skeletal muscle weakness; respiratory weakness; drooling; speech impairment; maximum motor function achieved: climb 4 stairs with handrail; electron microscopy result [catalog.coriell.org] The nebulin gene codes for the giant sarcomeric protein nebulin, which plays a crucial role in skeletal muscle contractile performance. [jmg.bmj.com] Nemaline Myopathy Type 5 INTRODUCTION: Nemaline myopathy (NM) is a congenital neuromuscular disorder often characterized by hypotonia, facial weakness, skeletal muscle weakness, and the presence of [ncbi.nlm.nih.gov] Introduction : Nemaline myopathy (NM) is a congenital neuromuscular disorder often characterized by hypotonia, facial weakness, skeletal muscle weakness, and the presence [pubfacts.com] Hypergonadotropic Hypogonadism - Partial Alopecia Characterized by slowly progressive skeletal muscle weakness of the hip and shoulder girdles. Muscle biopsy shows mild dystrophic changes. [ab-y-ss.com] Characterized by slowly progressive skeletal muscle weakness of the hip and shoulder girdles. Muscle biopsy shows mild dystrophic changes.. [antibodyplus.com] LGMD1B is characterized by slowly progressive skeletal muscle weakness of the hip and shoulder girdles. Muscle biopsy shows mild dystrophic changes. [abcam.cn] Polymyositis It presents with symmetric proximal muscle weakness and elevated skeletal muscle enzymes. [visualdx.com] DEFINITION Polymyositis is an idiopathic inflamatory myopathy that causes symmetrical proximal muscle weakness, elevated skeletal muscle enzyme levels,characteristic electromyograhic [de.slideshare.net] The inflammatory myopathies represent the largest group of acquired and potentially treatable causes of skeletal muscle weakness. [accessmedicine.mhmedical.com] Congenital Fiber-Type Disproportion Myopathy Abstract Congenital myopathies are clinical and genetic heterogeneous disorders characterized by skeletal muscle weakness and specific structural changes in muscle fiber. [ncbi.nlm.nih.gov] Congenital myopathies are clinical and genetic heterogeneous disorders characterized by skeletal muscle weakness and specific structural changes in muscle fiber. [pubfacts.com] The myopathy may be progressive and individuals with extensive skeletal muscle weakness may have respiratory insufficiency and scoliosis. [disorders.eyes.arizona.edu] Erb Muscular Dystrophy Muscle weakness can begin as early as age 3, first affecting the muscles of the hips, pelvic area, thighs and shoulders, and later the skeletal (voluntary) muscles in the [mda.org] Inherited disease that causes progressive weakness in the skeletal (and occasionally heart) muscle. [seslisozluk.net] Patients present with muscle weakness in these anatomic areas. The muscle weakness eventually spreads to other skeletal muscles as well. [icd10data.com] Nemaline Myopathy Nemaline myopathy (NM) is a congenital neuromuscular disorder often characterized by hypotonia, facial weakness, skeletal muscle weakness, and the presence of rods on muscle [ncbi.nlm.nih.gov] Patients develop large joint contractures during childhood, followed by slowly progressive skeletal muscle weakness during adulthood. [ncbi.nlm.nih.gov] [Total: 3 Average: 2.7/5] Nemaline Myopathy Definition Nemaline myopathy (NM) is an inherited congenital neuromuscular condition characterized by skeletal muscle weakness [primehealthchannel.com] Becker Muscular Dystrophy Patients are often wheelchair-bound by age 12 Becker is characterized by later-onset skeletal muscle weakness Patients remain ambulatory into their 20s Despite milder skeletal [en.wikibooks.org] There is symmetric skeletal muscle weakness/wasting without denervation (sensation and reflexes are intact). [openanesthesia.org] May be the presenting feature, if muscle weakness is mild. [patient.info] Myasthenia Gravis Myasthenia gravis (MG) is a neuromuscular autoimmune disease characterized by skeletal muscle weakness which can impact motor function and, furthermore, produce negative impact [ncbi.nlm.nih.gov] Abstract Myasthenia gravis is a chronic neuromuscular disorder that causes skeletal muscle weakness. [ncbi.nlm.nih.gov] Myasthenia gravis is an autoimmune disease of the neuromuscular junction characterized by painless fluctuating skeletal muscle weakness. [ncbi.nlm.nih.gov] Duchenne Muscular Dystrophy Duchenne muscular dystrophy (DMD) is an X-linked recessive disorder affecting 1 in 3,500 males, characterized by progressive skeletal muscle weakness and death secondary to [ncbi.nlm.nih.gov] Several important methods have been considered standard-in-the-field for analyses of skeletal muscle weakness, strength, endurance, and histopathology, as well as responses [ncbi.nlm.nih.gov] Duchenne muscular dystrophy (DMD) is an X-linked recessive disorder, characterized by progressive skeletal muscle weakness, loss of ambulation, and death secondary to cardiac [ncbi.nlm.nih.gov] Acute Gastroenteritis Hypokalemic periodic paralysis is a condition, characterized by episodic weakness of the skeletal muscle. It may be presented as familial or sporadic (secondary). [ncbi.nlm.nih.gov] Carnitine Transporter Deficiency Children with the childhood myopathic (cardiac) type usually present between ages two to four with heart disease (cardiomyopathy), low muscle tone (hypotonia), skeletal muscle [rarediseases.org] weakness, and elevated serum creatine kinase. [rarediseases.org] Some children with the infantile presentation may also have symptoms of muscle disease. [rarediseases.org] Glycogen Storage Disease Type 2 The adult onset form presents in the third to sixth decade and is similar to the juvenile form but with a slower progression of skeletal muscle weakness. [genedx.com] GSD2 is characterized by respiratory and skeletal muscle weakness and atrophy, resulting in functional disability and reduced life span. [ncbi.nlm.nih.gov] […] to the degree of skeletal muscle weakness should raise the suspicion of Pompe disease. [dx.doi.org] Vitamin D Deficiency As the Vitamin D Council explains, without the vitamin, our bodies may lose bone tissue, leading to bone pain, muscle weakness and possible skeletal deformity. [aplaceformom.com] […] signs and symptoms of osteomalacia (bone pain and tenderness, proximal muscle weakness reported as difficulty in rising from a sitting position). [bestpractice.bmj.com] We present a case of a 30-year-old woman presented with muscle weakness, weight loss, hypercalcaemia and a pathological fracture, eventually with rapidly progressive musculoskeletal [ncbi.nlm.nih.gov] Alpha-B Crystallinopathy However, muscular dystrophy is used to describe primary myopathies with a genetic basis and a progressive course characterized by progressive skeletal muscle weakness and [ncbi.nlm.nih.gov] muscle weakness. [ncbi.nlm.nih.gov] Muscular dystrophy (MD) refers to a group of more than 30 genetic diseases characterized by progressive weakness and degeneration of the skeletal muscles that control movement.Some [monarchinitiative.org] Hereditary Proximal Myopathy with Early Respiratory Failure Hereditary myopathy with early respiratory failure ( HMERF ) is characterized by adult-onset distal or proximal skeletal muscle weakness with respiratory muscle weakness involvement [invitae.com] Methods Whole exome sequencing analysis was carried out in a large U.S. family that included seven members suffering from skeletal muscle weakness and respiratory failure. [bmcneurol.biomedcentral.com] Myasthenia gravis may present with respiratory failure with skeletal muscle weakness [ Qureshi et al 2004 ]. [ncbi.nlm.nih.gov] Myopathic Carnitine Deficiency Patients can clinically present with cardiomyopathy, skeletal muscle weakness, myalgia, and extreme fatigue. [allmedx.com] Disease presents in early childhood with a progressive heart disorder (cardiomyopathy) and skeletal muscles weakness and pain (myopathy), low blood levels of L-carnitine, [nutrientsreview.com] Children with the childhood myopathic (cardiac) type usually present between ages two to four with heart disease (cardiomyopathy), low muscle tone (hypotonia), skeletal muscle [rarediseases.org] Limb-Girdle Muscular Dystrophy Type 1H Affiliated tissues include skeletal muscle, and related phenotypes are centrally nucleated skeletal muscle fibers and muscle weakness Disease Ontology : 12 An autosomal dominant [malacards.org] LGMD1B is characterized by slowly progressive skeletal muscle weakness of the hip and shoulder girdles. Muscle biopsy shows mild dystrophic changes. [abcam.com] Myofibrillar Myopathy Type 4 MFM3 is characterized by progressive skeletal muscle weakness greater distally than proximally, tight heel cords, hyporeflexia, cardiomyopathy and peripheral neuropathy in [genecards.org] Skeletal muscle weakness typically starts in distal leg muscles and spreads to proximal muscles, a trend that is about 3 times more common than the opposite ( 69 ). [jci.org] BMD is characterized by later onset skeletal muscle weakness; some individuals remain ambulatory into their 20s. [blueprintgenetics.com] Emery-Dreifuss Muscular Dystrophy Type 1 […] of the SKELETAL MUSCLE. [doctor.am] muscle weakness and degeneration. [biochemsoctrans.org] Muscular dystrophies are characterized by progressive skeletal muscle weakness, defects in muscle proteins, and the death of muscle cells and tissue. [disabled-world.com] Drug-induced Hypokalemia The principal clinical manifestations of potassium depletion are profound skeletal muscle weakness with loss of deep tendon reflexes, smooth muscle weakness resulting in paralytic [jamanetwork.com] Severe hypokalemia, with serum potassium concentrations of 2.5–3 meq/l (Nl: 3.5–5.0 meq/l), may cause muscle weakness, myalgia, tremor, and muscle cramps (owing to disturbed [en.wikipedia.org] […] involve several or all of the skeletal muscles with complete recovery between attacks[ 8, 9 ]. [wjgnet.com] Hypersensitivity In myasthenia gravis, for example, antibodies are produced that bind to and inactivate the acetylcholine receptors on skeletal muscle. [courses.washington.edu] Muscles become weak and easy to fatigue. [courses.washington.edu] Transient Neonatal Myasthenia Gravis Overview of Myasthenia Gravis Myasthenia gravis (MG) is a chronic autoimmune disorder that results in progressive skeletal muscle weakness. [healthcommunities.com] A defect in the transmission of impulses from nerve endings in the muscle fibers result in the development of skeletal muscle weakness. [hmcisrael.com] skeletal muscle weakness [5]. [intechopen.com] Hypokalemic Periodic Paralysis muscle weakness with associated hypokalemia which is precipitated by stress, cold, carbohydrate load, infection, glucose infusion, hypothermia, metabolic alkalosis, anesthesia [njms.in] which in turn leads to sodium (Na) inactivation, skeletal muscle weakness, or paralysis. [cureus.com] […] attacks of skeletal muscle weakness due to associated hypokalemia [1]. [medical-case-reports.imedpub.com] Chronic Progressive External Ophthalmoplegia Pharyngeal, facial, and skeletal muscle weakness seem to be common features. [disorders.eyes.arizona.edu] Although it can be seen in the absence of other clinical manifestations, CPEO is often associated with skeletal muscle weakness. [mussenhealth.us] muscle weakness. [emedicine.com] Kearns-Sayre Syndrome muscle weakness (proximal more than distal) and exercise intolerance are additional features. [ncbi.nlm.nih.gov] Additional symptoms may include mild skeletal muscle weakness, heart block (a cardiac conduction defect), short stature, hearing loss, an inability to coordinate voluntary [ninds.nih.gov] Additional symptoms may include: Mild skeletal muscle weakness Heart block (a cardiac conduction defect) Short stature Hearing loss An inability to coordinate voluntary movements [blouw.moneomed.com]
