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50 Possible Causes for Skin Biopsy Abnormal, Spontaneous Rupture of Membranes

  • Ehlers Danlos Syndrome

    EDS type IV was diagnosed with a skin biopsy for a collagen abnormality.[ncbi.nlm.nih.gov] Problems during delivery Due to the fragility of connective tissue, those with EDS are more prone to prelabour spontaneous rupture of membranes (SROM), including preterm SROM[patient.info] A skin biopsy disclosed an unremarkable dermis; electron microscopy showed abnormalities in the diameter, contour, and shape of collagen fibrils/fibers.[ncbi.nlm.nih.gov]

  • Staphylococcal Scalded Skin Syndrome

    Pregnancy was uncomplicated until 2 days before delivery when spontaneous rupture of membranes occurred.[jmedicalcasereports.biomedcentral.com]

  • Pruritic Urticarial Papules and Plaques of Pregnancy

    biopsy only if diagnostic uncertainty perivascular and interstitial lymphocytic infiltrate with eosinophils No lab abnormalities Differential Diagnosis Pemphigoid gestationis[medbullets.com] […] pregnancy, and pre-term rupture of membranes ( 121, 122 ).[frontiersin.org] Currently there are two theories: One study discovered male fetal DNA in skin rash biopsies of affected women.[womens-health-advice.com]

  • Ehlers-Danlos Syndrome Type 4

    A skin biopsy is used to check for signs of abnormalities in collagen production. This involves removing a small sample of skin and checking it under a microscope.[healthline.com] Problems during delivery Due to the fragility of connective tissue, those with EDS are more prone to prelabour spontaneous rupture of membranes (SROM), including preterm SROM[patient.info] […] of abnormal type I collagen Dermatosparaxis [12] AR Type VII C Severe skin fragility Sagging, redundant skin Soft, doughy skin texture Easy bruising Premature rupture of[physio-pedia.com]

  • Microscopic Polyangiitis

    Microscopic hematuria was detected but a renal biopsy showed no abnormalities.[ncbi.nlm.nih.gov] Spontaneous deliveries included those with spontaneous onset of labor and those with rupture of membranes before labor.[nejm.org] Histological examination of a skin biopsy from a purpuric papule showed leukocytoclastic vasculitis of the small vessels in the entire dermis.[ncbi.nlm.nih.gov]

  • Syringocystadenoma papilliferum

    […] was obtained by a dermatologist and histopathologic evaluation was reported to show subareolar sclerosing duct hyperplasia without abnormalities of the skin.[bmcdermatol.biomedcentral.com] 69-11 An unusual histological cataract 70-03 Spontaneous rupture of the lens capsule 71-19 Asteroid hyalosis 72-28 Granulomatous anterior uveitis and hyalitis 73-32 Aicardi's[helsinki.fi] Subsequently, one month later, a larger 6 mm punch biopsy was performed by a breast surgical oncologist to the same region of the right breast and histopathologic evaluation[bmcdermatol.biomedcentral.com]

  • Vulvovaginal Disorder

    The treatment is surgical removal or laser destruction of the skin abnormalities. Why are self-exams important?[ochsner.org] […] miscarriage, premature rupture of membranes, pre-term labour and infections following gynaecological surgical procedures, e.g. termination of pregnancy or hysterectomy. 5,7[bpac.org.nz] The diagnosis is made by examining the area with a special scope or magnifying lens plus a biopsy.[ochsner.org]

  • Erythromelalgia

    MAIN OUTCOME MEASURE: Evidence of microvascular abnormalities in skin biopsy specimens.[ncbi.nlm.nih.gov] Spontaneous firing is increased in intact DRG neurons expressing hNav1.7-A1632G Whole-cell current-clamp study requires rupturing the cell membrane and dialyzing the cells[doi.org] Pathophysiology The first insights into the pathophysiology of erythromelalgia associated with thrombocythemia were gained when skin biopsy samples revealed arteriolar fibrosis[emedicine.medscape.com]

  • Globoid Cell Leukodystrophy

    This testing generally includes a blood test and/or skin biopsy to evaluate the levels of galactosylceramidase, the enzyme that is low in people with Krabbe disease.[rarediseases.info.nih.gov] Case report Female triplets were born by caesarean delivery after spontaneous membrane rupture following a 36-week first pregnancy.[docslide.com.br] : 7/5/2015 A diagnosis of Krabbe disease may be suspected based on the presence of characteristic signs and symptoms or in certain states of the United States, due to an abnormal[rarediseases.info.nih.gov]

  • Telangiectasia Macularis Eruptiva Perstans

    […] intraepidermal nerve fiber density (IENFD) in skin biopsy, and/or abnormal temperature thresholds levels in...[medworm.com] Small arteriovenous malformations (telangiectasias) close to the surface of the skin, and mucous membranes often rupture and bleed after slight trauma.[onlinelibrary.wiley.com] Skin biopsy was taken, and histopathologic examination revealed proliferation of mast cells with ovoid and spindle nuclei with distinct cytoplasm borders around the capillaries[e-ijd.org]

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