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43 Possible Causes for Skin Lesions with Central Clearing

  • Erythema Chronicum Migrans

    A Skin lesion with central clearing, in right lower quadrant of abdomen. Raised lesion marks indicate from which area the attached tick was removed.[] The skin lesion (24 patients) typically lasted about 3 weeks, beginning as a red macule or papule that expanded to form a large ring with central clearing.[] B Skin lesion in left upper quadrant of abdomen, below surgical scar Figure 1 Erythema migrans of case patient and point of attachment of female Amblyomma americanum tick.[]

  • Lyme Disease

    Early skin lesions have an expanding ring form, often with a central clear zone. Fever, chills, myalgia and headache are common. Meningeal involvement may follow.[] […] lesion, often with partial central clearing.[] For purposes of surveillance, EM is defined as a skin lesion that typically begins as a red macule or papule and expands over a period of days to weeks to form a large round[]

  • Syphilis

    There's no statute of limitations on the violation of human rights in medical research, the U.S. government acknowledged Friday. Secretary of State Hillary Clinton and Health and Human Services Secretary Kathleen Sebelius apologized for a U.S.-funded study that led to the deliberate infection of hundreds of[…][]

  • Tinea Corporis

    They are annular in configuration with concentric rings, and central clearing. Scrapings of the lesions are tested, and a topical medication is prescribed .[] It usually produces a ring-shaped lesion which appears to clear in the center. The edges of the lesion may be slightly raised and often itch.[] Introduction Clinical definition superficial fungal infection of the skin "corporis" "body" affected areas include the trunk, legs, arms, and neck does not include the feet[]

  • Secondary Syphilis

    It is essential that healthcare providers are familiar with the full spectrum of clinical presentations of syphilis. A rare manifestation of secondary syphilis is the corymbiform (or corymbose) arrangement, in which a central greater papule is surrounded by smaller satellite lesions. Very few reports of corymbiform[…][]

  • Pityriasis Circinata

    […] to herald patch Small fawn or salmon colored oval Macule s Peripheral scaly collarettes Central clearing Darker skin: Black Children More facial (30% of cases) and scalp[] clearing Christmas tree pattern rash Onset occurs 7-14 days after herald patch Lesions may continue to appear for up to 6 weeks after onset Symmetric bilaterally Smaller[] […] than herald patch ( Rash follows skin Cleavage Lines ( Langer Lines ) Christmas-Tree distribution on back V-Shaped distribution on the chest Individual lesions appear similar[]

  • Tinea Pedis

    The differential diagnosis includes other annular skin lesions. Most patients with tinea corporis are diagnosed clinically.[] Patients typically present with an annular patch or plaque with an advancing, raised, scaling border and central clearing ( Figure 2 ).[]

  • Urticaria

    Maculopapular erythema The bullous type Skin lesions may show hemorrhagic bullae on an erythematous base.[] The maculopapular type Well-defined erythematous maculopapules, which spread peripherally forming polycyclic patches with central clearing.[]

  • Transient Sarcoidosis

    The most common cutaneous lesions of sarcoidosis are brown-red or purple papules and plaques. Through central clearing, annular or circinate lesions may result.[] This autosomal dominant disorder is marked by granulomatous inflammation of the skin, uveal tract, and joints, sparing the lungs.[]

  • Glucagonoma

    Scaling and central clearing seems to indicate that these lesions start to heal, but vesicles and bullae may form in peripheral regions, rupture, ulcerate and become infected[] NME spreads and may eventually affect large parts of the skin. Patients often claim pain and pruritus.[]

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