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53 Possible Causes for Skin Lesions with Central Clearing

  • Lyme Disease

    Early skin lesions have an expanding ring form, often with a central clear zone. Fever, chills, myalgia and headache are common. Meningeal involvement may follow.[who.int]

  • Erythema Chronicum Migrans

    The skin lesion (24 patients) typically lasted about 3 weeks, beginning as a red macule or papule that expanded to form a large ring with central clearing.[annals.org]

  • Tinea Corporis

    They are annular in configuration with concentric rings, and central clearing. Scrapings of the lesions are tested, and a topical medication is prescribed .[step2.medbullets.com] Introduction Clinical definition superficial fungal infection of the skin "corporis" "body" affected areas include the trunk, legs, arms, and neck does not include the feet[step2.medbullets.com]

  • Secondary Syphilis

    A 62-year-old male presented with a 10-day history of a diffuse, erythematous papular rash sparing the palms and soles. Histopathologic examination of a skin lesion showed loose non-caseating granulomas in a lymphoplasmacytic background. Scattered spirochetes were identified by Treponema pallidum[…][ncbi.nlm.nih.gov]

  • Syphilis

    As evidenced by the Centers for Disease Control and Prevention (CDC) statistics, syphilis is yet again on the rise. It is known as the great mimicker because of its variable symptoms and how frequently it can be confused with other diseases. The different stages of syphilis (primary, secondary, latent, late latent[…][ncbi.nlm.nih.gov]

  • Familial Keratoacanthoma

    The appearance of recurrent nodular skin lesions with central clearing and progressive peripheral spreading on the distal extremities, 6 in the setting of the histopathological[pagepress.org]

  • Urticarial Vasculitis

    clearing of lesions, and residual hyperpigmentation following resolution.[ncbi.nlm.nih.gov] The cutaneous features may include painful, burning or pruritic skin lesions, the persistence of individual lesions greater than 24 hours, palpable purpura, pronounced central[ncbi.nlm.nih.gov] However, because clinical characteristics of urticarial vasculitis may overlap with those of allergic urticaria, confirmation of the diagnosis requires a lesional skin biopsy[ncbi.nlm.nih.gov]

  • Local Lupus Erythematosus

    Two years later, the patient continued to be free of skin lesions. Figure 1. Annular plaques on the upper chest with overlying scale and focal central clearing.[mdedge.com] On follow-up examination 1 month after discontinuation of imiquimod, the patient’s skin lesions had completely cleared.[mdedge.com]

  • Lyme Disease Vaccine

    Following a tick bite 80% of people will develop a red, slowly expanding ring form of skin lesions around the bite, often with a central clear zone.[welltogo.com.au]

  • Erythrasma

    The infected skin is often reddish-brown, may be slightly raised from the surrounding skin and may show the appearance of central clearing.[skincarenet.org] The lesions may appear with central clearing and be slightly raised from the surrounding skin ( Figure 119-5 ).[accessmedicine.mhmedical.com] The lesions may become brownish and appear slightly raised from the surrounding skin with the appearance of central clearing.[aafp.org]

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