— redness, erosions, maceration Vagina — inflamed mucosa Not reported in drug-induced pellagra or Hartnup disease Skin thickening and pigmentation Slow onset of hyperkeratosis
[dermnetnz.org]
It was first described by Don Casal, a Spanish court physician in the 1700s, where thickened skin was noted in peasants.
[patient.info]
Initially resembles sunburn – acute onset, red, swollen, painful burning Occasional vesicles and/or bullae Persistent redness, scaling, pigmentation Becomes hyperpigmented, thickened
[dermnetnz.org]
