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334 Possible Causes for Skin Thickening, Soft Tissue Swelling

  • Acromegaly

    (sebaceous glands) causing oily skin, thickening of the skin, skin tags (growths) Sleep apnea Widened fingers or toes, with swelling, redness, and pain Other symptoms that[nlm.nih.gov] This leads to coarse facial features, soft tissue swelling (including the tongue), enlargement of the hands and feet, respiratory problems, hypertension, diabetes mellitus[ncbi.nlm.nih.gov] Injections often improve symptoms of soft tissue swelling, headache, joint pains and sleep apnea. Patients require lifelong treatment with somatostatin.[pietromortini.com]

  • Mucopolysaccharidosis

    Thickened skin and mild changes in facial features, bone, and skeletal structures become noticeable with age. Growth in height usually stops by age 10.[en.wikipedia.org] Non-specific cutaneous changes that can be seen in all mucopolysaccharidoses are thickened skin with a loss of elasticity on elbows and knees, rough hair and hypertrichosis[actasdermo.org] A distinctive facies with thickening of lips and nostrils as well as an enlarged and protruding tongue forms slowly and may become evident between 2-4 years of age, later[orpha.net]

  • Eosinophilic Fasciitis

    We describe a woman who presented with unilateral progressive skin thickening.[ncbi.nlm.nih.gov] […] and soft tissues.[ncbi.nlm.nih.gov] Painful swelling with progressive induration and thickening of the skin and soft tissues of the limbs and trunk are the clinical hallmarks of the disease.[ncbi.nlm.nih.gov]

  • Primary Hypertrophic Osteoarthropathy

    […] new bone First smooth, then undulating rough, most conspicuous on concavity of long bones (dorsal and medial aspects) Regression of periosteal reaction after thoracotomy Soft-tissue[learningradiology.com] Patients present with joint pain, limb enlargement, skin thickening and finger clubbing.[ncbi.nlm.nih.gov] thickening.[ncbi.nlm.nih.gov]

  • Common Cold

    When suffering from a cold the soft tissues surrounding the sinuses and the Eustachian Tube can swell making the inward movement of air during the descent difficult, and sometimes[skybrary.aero] Itchy, watery eyes and nose are classic signs of an allergy , as are repeated sneezing attacks and itchy skin that lasts for weeks or months.[babycenter.com] Also with allergies, the mucus coming out of your child's nose will continue to run clear, rather than thickening and turning yellow or green as it tends to in children with[babycenter.com]

  • Rhinophyma

    Grade 1: prominent follicular openings with no skin thickening Grade 2: prominent follicular openings with mild skin thickening Grade 3: prominent follicular openings, skin[dermnetnz.org] Rhinophyma is a swelling of the soft tissue of the nose due to sebaceous gland hypertrophy, lymphoedema and fibrosis.[ncbi.nlm.nih.gov] It is a progressive condition wherein the skin becomes thickened and the sebaceous (oil) glands enlarge.[enrichclinic.com.au]

  • Sclerodactyly

    Principal changes include skin thickening, accumulation of collagen, and atrophy of the surrounding tissues with fibrosis.[symptoma.com] Underlying soft tissues can atrophy and depending on severity, sclerodactyly can cause disability.[sclero.org] Initial changes include skin thickening and dermal sclerosis, as a result of fibroblast activation, and accumulation of collagen and skin vessel damage, resulting in damage[symptoma.com]

  • Stasis Dermatitis

    Pressure stockings or wraps can be used to help mechanically move the fluid out of the skin and soft tissues.[nationaleczema.org] As stasis dermatitis progresses, skin thickens, and sores may break open and ooze excess fluid [source: VisualDXHealth ].[health.howstuffworks.com] […] or legs Development of ulcers and sores in the weak skin area Pain in the legs Cracks in the affected region of the skin Thickened skin in the affected leg region Formation[hxbenefit.com]

  • Exostosis

    It is characterized by pain, soft tissue swelling and a growing mass leading to limitation of motion and cosmetic deformity.[link.springer.com] The excessive pressure often forms a callus or thickening of the skin. People who have diabetes should watch these areas carefully.[podiatrynetwork.com] Lumps and Bumps in the Ball of the Foot Painful lumps in the ball of the foot are usually but not always associated with a thickening of the skin or callus.[podiatrynetwork.com]

  • Elephantiasis

    People with lymphedema are prone to bacterial infections that can lead to a mobility-limiting condition where the skin thickens and hardens.[unitingtocombatntds.org] Usually, the upper and lower limbs are affected, but often swelling of the scrotum, vulva and breasts are observed. Soft tissue swelling is sometimes very significant.[medical-enc.com] thickening) Scrotal swelling in men Pain Diagnosis Laboratory testing of blood samples There is a new rapid diagnostic test which detects the presence of the filarial worm[drasatrust.org]

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