Slow Nerve Conduction Velocity: Causes & Reasons

Possible Causes for Slow Nerve Conduction Velocity

Nerve conduction velocities are slow, and distal latencies are prolonged. Segmental demyelination and remyelination occur. Enlarged peripheral nerves may be palpated. [msdmanuals.com]

nerve conduction velocities ( Many phenotypic variants have been reported. [karger.com]

Natural history varies: Some patients are asymptomatic and have only slowed conduction velocities (detected on nerve conduction studies); others are more severely affected [msdmanuals.com]

Guillain-Barré Syndrome

Nerve conduction analysis will reveal slow nerve conduction velocities due to the damage to the nerve. [emedicinehealth.com]

conduction velocities are greatly reduced, and sensory nerve conduction time is often slow o evidence of acute denervation of muscle Serum Creatine Kinase o Elevated or normal [slideshare.net]

[…] signs Elevation of CSF protein after 1 week of symptom Slowed nerve conduction velocity Autonomic dysfunction From National Institute of Neurologic and Communicative Disorders [slideshare.net]

Uremic Neuropathy

Case 58A A Woman with Leg Numbness Pain Weakness and Slow Nerve Conduction Velocities 372 Case 58B A Boy with Leg Weakness 375 Case 59 A Man with Hand Weakness and Numbness [books.google.com]

 Motor nerve conduction velocity - often measured in peroneal nerve - often measured in peroneal nerve - slowing of nerve conduction velocity - slowing of nerve conduction [slideplayer.com]

The nerve conduction velocity was slow and the F response delayed, suggestive of demyelinating neuropathy. [karger.com]

Charcot-Marie-Tooth Disease

HMSN1 is the most common form of hereditary neuropathy, characterized by severely and uniformly slowed nerve conduction velocities and primary hypertrophic myelin pathology [medlink.com]

A broad division may be made between HMSNs with diffusely slow nerve conduction velocity and those with normal or borderline abnormal nerve conduction velocity. [16] HMSN [emedicine.medscape.com]

Ulnar Nerve Entrapment

An electromyographic (EMG) investigation revealed slowing of the motor conduction velocity in the ulnar nerve across the elbow. [ncbi.nlm.nih.gov]

The most reliable finding is slowing of the ulnar across-elbow motor nerve conduction velocity to less than 50 m/sec while recording from the abductor digiti minimi muscle [ncbi.nlm.nih.gov]

Motor nerve conduction studies may show focal slowing of nerve conduction velocity in the ulnar nerve segment crossing the elbow (2). [journals.lww.com]

Peroneal Nerve Compression Neuropathy

Slowing of peroneal nerve conduction velocities at the fibula head may or may not be detected. [neupsykey.com]

There was a focal slowing of the maximum nerve condition velocity across the neck of the fibula. [oandplibrary.org]

Amplitudes can also be compared with the contralateral unaffected peroneal nerve or if necessary to normal control values. [neupsykey.com]

Hereditary Sensory Neuropathy

[…] be distinguished from each other by the typical findings in nerve conduction velocities (marked slowing of motor nerve conduction velocity uniformly in all peripheral nerves [annalsofian.org]

Group 1 was characterized by slow nerve conduction velocities and evidence of hypertrophic demyelinating neuropathy. [emedicine.medscape.com]

Motor nerve conduction velocities are mildly slowed and motor action potentials are reduced in advanced cases. [ncbi.nlm.nih.gov]

Chronic Inflammatory Demyelinating Polyneuropathy

Tests that can be of diagnostic help include nerve conduction testing and electromyography looking for very slow nerve conduction velocities, lumbar puncture looking for elevated [rarediseases.org]

Although the patient noticed little muscle weakness, an electrophysiological study demonstrated slow conduction velocities and prolonged distal latencies, with definite conduction [ncbi.nlm.nih.gov]

Primary demyelination leads to nerve conduction velocity slowing, distal latency prolongation, and F-wave latency prolongation or absence. [em-consulte.com]

Demyelinating Disease

This will give a falsely slow conduction velocity. [ncbi.nlm.nih.gov]

Nerve conduction velocity slowed because of multifocal destruction of myelin segments involving many axons within a peripheral nerve What abnormalities would you see in [quizlet.com]

Carpal Tunnel Syndrome

Median nerve conduction velocities are slowed along the wrists and hands of people with CTS. [handandwristinstitute.com]

Picture of carpal tunnel syndrome The diagnosis is strongly suggested when a nerve conduction velocity test is abnormal. [medicinenet.com]

A test of muscles of the extremity, electromyogram ( EMG ), is sometimes performed with the nerve conduction velocity test to exclude or detect other conditions that might [medicinenet.com]

Peripheral Neuropathy

Nerve conduction studies can distinguish demyelinative neuropathy (slowing of conduction velocity or conduction block) from axonal neuropathy (low-action potential amplitudes [neuropathology-web.org]

Nerve conduction studies assess the shape, amplitude, latency, and conduction velocity of an electrical signal conducted over the tested nerve. [aafp.org]

Axonal loss leads to lower amplitudes, and demyelination causes prolonged latency and slow conduction velocity. [aafp.org]

Diabetic Peripheral Neuropathy

[…] of nerve conduction velocities, an indicator of demyelination. [nejm.org]

[4] Sensorimotor polyneuropathy [ edit ] Longer nerve fibers are affected to a greater degree than shorter ones because nerve conduction velocity is slowed in proportion [en.wikipedia.org]

The decrease in sensory and motor amplitudes, indicating axonal destruction, was more pronounced than the slowing of the nerve conduction velocities, which indicates demyelination [nejm.org]

Diabetic Mononeuropathy

[4] Sensorimotor polyneuropathy [ edit ] Longer nerve fibers are affected to a greater degree than shorter ones because nerve conduction velocity is slowed in proportion [en.wikipedia.org]

Prolonged distal latencies Motor & Sensory nerves Conduction velocities: Mildly slowed Amplitudes: Normal Anatomy: Legs more involved than arms Triglyceride level: High [neuromuscular.wustl.edu]

[…] to a nerve's length. [en.wikipedia.org]

Serum Neuropathy

Nerve conduction studies assess the shape, amplitude, latency, and conduction velocity of an electrical signal conducted over the tested nerve. [aafp.org]

Because axons of a chronically demyelinated nerve display different conduction velocities (known as temporal dispersion, TD), the positive phase of the fast motor-unit action [karger.com]

Axonal loss leads to lower amplitudes, and demyelination causes prolonged latency and slow conduction velocity. [aafp.org]

Hereditary ATTR Amyloidosis

In CIDP, large myelinated fiber dysfunction predominates, with slow conduction velocity, high cerebrospinal fluid (CSF) protein content, and virtually no symptoms of autonomic [ncbi.nlm.nih.gov]

In addition, nerve conduction velocity is often mildly decreased in patients with TTR-FAP, and CSF protein content can be elevated, which may increase the confusion with CIDP [ncbi.nlm.nih.gov]

Paraneoplastic Polyneuropathy

Myelin loss results in slowed conduction velocities, prolonged distal latencies, conduction block, temporal dispersion and prolonged minimum F-wave latencies. [aafp.org]

The differential diagnosis of different types of peripheral neuropathy can be divided using electrophysiologic criteria. 7 Axon loss results in loss of amplitude of nerve [aafp.org]

Metachromatic Leukodystrophy

Each child had significant slowing of motor nerve conduction velocity (NCV). [ncbi.nlm.nih.gov]

Protein levels in cerebral spinal fluid (CSF) were elevated and nerve conduction studies revealed slowing down of motor nerve conduction velocity. [ncbi.nlm.nih.gov]

In the infantile and juvenile variants, the conduction velocity of peripheral nerves is markedly reduced. [78stepshealth.us]

Cockayne Syndrome

Nerve conduction velocity showed slow motor conduction suggestive of demyelination. His electroencephalogram was normal. [ijdvl.com]

In peripheral nerves, loss of myelin is marked by slow conduction velocities. CSF protein levels are often elevated. [ncbi.nlm.nih.gov]

Krabbe Disease

Examination shows motor spasticity as well as slowed motor and sensory conduction velocities on nerve conduction studies. [knowledge.statpearls.com]

Brachial Plexus Neuropathy

We describe brachial plexus neuropathy with high-dose cytarabine (Ara-C) therapy in a man who had acute monoblastic leukemia. Signs and symptoms of brachial plexus neuropathy appeared on two occasions within hours of exposure to high-dose Ara-C. Central nervous system complications have been described following[…] [ncbi.nlm.nih.gov]

Distal Spinal Muscular Atrophy Type 5

People with early-onset CMT1B tend to have very slow nerve conduction velocities, with speeds 50 m/s). [cmtausa.org]

Conduction velocities were normal or low-normal except for slowing in the demyelinative range at areas of nerve entrapment, where amplitudes were also low. [emedicine.medscape.com]

Neurophysiology Autosomal dominant CMT1 and CMT3, and autosomal recessive CMT4: uniformly slow nerve conduction velocities (NCV) with median and ulnar motor NCV (MNCV) 38 [neupsykey.com]

Ilioinguinal Nerve Entrapment

The anatomy of the ilioinguinal nerve makes it vulnerable to entrapment near its exit from the superficial inguinal ring, where it lies almost directly superior to the pubic tubercle. Ilioinguinal nerve entrapment is a documented complication of inguinal herniorrhaphy, inguinal lymph node dissection, appendectomy,[…] [ncbi.nlm.nih.gov]

Déjerine-Sottas Disease

The parents were heterozygous first cousins with subclinical CMT1B and slow nerve conduction velocities. [ncbi.nlm.nih.gov]

nerve conduction velocity. [ncbi.nlm.nih.gov]

nerve conduction velocities and elevated CSF protein. [genome.jp]

Charcot-Marie-Tooth Disease Type 2S

Most patients with DSS have extremely slow nerve conduction velocities. [cmt.org.uk]

People with early-onset CMT1B tend to have very slow nerve conduction velocities, with speeds 50 m/s). [cmtausa.org]

It is difficult to distinguish between DSS and CH since both have severe pathological changes on sural nerve biopsies and both have very slow nerve conduction velocities. [cmt.org.uk]

Distal Hereditary Motor Neuropathy Type 1

Charcot-Marie-Tooth neuropathy type 1 (CMT1) is a demyelinating peripheral neuropathy characterized by distal muscle weakness and atrophy, sensory loss, and slow nerve conduction [bcbst.com]

HMSN1 is the most common form of hereditary neuropathy, characterized by severely and uniformly slowed nerve conduction velocities and primary hypertrophic myelin pathology [medlink.com]

Classification The major categories of Charcot-Marie-Tooth are Types 1 through 7 an X-linked category Classification of CMT Type I A demyelinating condition that slows nerve [orthobullets.com]

Hereditary Areflexic Dystasia

CHN is characterized clinically by early onset of hypotonia, areflexia, distal muscle weakness, and very slow nerve conduction velocities. [abcam.com]

Most patients with DSS have extremely slow nerve conduction velocities. [mydr.com.au]

DSS is characterized by motor and sensory neuropathy with very slow nerve conduction velocities, increased cerebrospinal fluid protein concentrations, hypertrophic nerve changes [abcam.com]

Inherited Neuropathy

Group one was characterized by slow nerve conduction velocities and demyelinating neuropathy. [en.wikipedia.org]

Charcot-Marie-Tooth neuropathy type 1 (CMT1) is a demyelinating peripheral neuropathy characterized by distal muscle weakness and atrophy, sensory loss, and slow nerve conduction [bcbst.com]

Diminished conduction velocity and action potential amplitude along motor and sensory nerves in affected and unaffected nerves with focal conduction slowing or block at common [medlink.com]

Lower Motor Neuron Syndrome with Late-Adult Onset

[…] biopsy: atrophic fibers & fiber type grouping -several nerves weakness in nerve distribution -slow nerve conduction velocities -denervation & decreased # of motor units on [brainscape.com]

People with early-onset CMT1B tend to have very slow nerve conduction velocities, with speeds 50 m/s). [cmtausa.org]

[…] block of a motor nerve; slowing of conduction velocities in two or more motor nerves; prolonged distal motor latencies in two or more nerves; and prolonged or absent F-waves [consultant360.com]

Familial Progressive Polyneuropathy

Group one was characterized by slow nerve conduction velocities and demyelinating neuropathy. [en.wikipedia.org]

Nerve conduction velocities are slow, and distal latencies are prolonged. Segmental demyelination and remyelination occur. Enlarged peripheral nerves may be palpated. [merckmanuals.com]

nerve conduction velocities ( Many phenotypic variants have been reported. [karger.com]

Distal Hereditary Motor Neuropathy Type 5A

Charcot-Marie-Tooth neuropathy type 1 (CMT1) is a demyelinating peripheral neuropathy characterized by distal muscle weakness and atrophy, sensory loss, and slow nerve conduction [bcbst.com]

Electrophysiology: nerve conduction studies show: Low conduction velocities ( Normal or only mildly slowed conduction velocities (>38 m/s) and reduced action potential amplitudes [patient.info]

velocity. [bcbst.com]