Small Brain: Causes & Reasons

Possible Causes for Small Brain

brains and a life expectancy of between five and six months the chance alteration of gene frequencies in a population, with such alterations having greatest impact on small [quizlet.com]

[…] head) from birth, brain hypoplasia (underdeveloped brain), micrognathia (small chin), irritability (at second or third month of age), seizures, problems controlling their [en.wikipedia.org]

[…] head and a small brain. [icdlist.com]

Microcephaly

Micrencephaly (an abnormally small brain) was observed, with almost complete agyria, hydrocephalus, and multifocal dystrophic calcifications in the cortex and subcortical [ncbi.nlm.nih.gov]

Patients with rare genetic mutations shed light on how Zika virus causes microcephaly "The current study was initiated when a patient presented with a small brain size at [sciencedaily.com]

The term micrencephaly refers to "small brain," and this is a pathological term. [medlink.com]

Vascular Dementia

Small blockages deprive some brain cells of oxygen, causing a series of small strokes that kill brain cells. [health.harvard.edu]

[…] strokes that progressively destroy the brain. [britannica.com]

It is caused by small blood clots preventing oxygen reaching the brain tissue. The small clots are sometimes known as Transient Ischaemic Attacks or TIAs. [dementiauk.org]

Ruptured Cerebral Aneurysm

Treatment Options A small brain aneurysm that has not ruptured may only need to be monitored; however, if the aneurysm is large, has high-risk features, or has burst, it may [neurosurgery.wustl.edu]

Many people live with small brain aneurysms that go unnoticed. [brighamandwomens.org]

[…] patient’s brain blood vessels. [neurosurgery.wustl.edu]

CADASIL Syndrome

What is Small Vessel Disease (SVD)? SVD refers to pathological processes that affect the structure and function of small penetrating vessels within the brain. [uvm.edu]

small-vessel disease myotonic dystrophy type 1 think of it in younger patients with small vessel ischemic white matter change predilection for anterior temporal lobe white [radiopaedia.org]

It is a progressive disorder of the small arteries of the brain leading to brain infarcts, migraine, seizures, mood disorders / severe depressive episodes, cognitive impairment [ctgt.net]

Multi-Infarct Dementia

It can also cause small infarcts near the base of the brain. Small vessel disease develops much deeper in the brain than the damage caused by many strokes. [alzheimers.org.uk]

In vascular dementia, the vessels blocked are very small, resulting in the death of small areas of brain tissue on the outer surface of the brain called the cerebral cortex [healthengine.com.au]

Small vessel disease often damages the bundles of nerve fibres that carry signals around the brain, known as white matter. [alzheimers.org.uk]

Congenital Neuronal Ceroid Lipofuscinosis

Infants with CLN10 disease have a small brain and small head ( microcephaly ). They also have problems controlling their movements. [rarediseases.info.nih.gov]

Infants with CLN10 disease have a small brain and small head (microcephaly). They also have problems controlling their movements. [rarediseases.org]

The areas of the brain involved in thinking and emotions are also severely affected. [rarediseases.info.nih.gov]

Berry Aneurysm

In summary, patients with small brain aneurysms that do not rupture (about 80%) have a very good prognosis while those who suffer a rupture have a fair to poor prognosis. [emedicinehealth.com]

The survival rate for those with a ruptured brain aneurysm is about 60% (40% die). For those who survive and recover, about 66% have some permanent neurological defect. [emedicinehealth.com]

Autosomal Recessive Primary Microcephaly Type 2

Nome malattia codice esenzione malattia di riferimento METAEMOGLOBINEMIA DA DEFICIT DI METAEMOGLOBINAREDUTTASI RDG010 ANEMIE EREDITARIE METAPLASIA MIELOIDE AGNOGENICA RD0070 ANEMIE APLASTICHE ACQUISITE (ESCLUSO: FORME MIDOLLARI APLASTICHE TRANSITORIE) METEMOGLOBINEMIA CONGENITA EREDITARIA RDG010 ANEMIE EREDITARIE[…] [malattierare.regione.veneto.it]

Brain. 2015 Aug. Abstract Cerebral small vessel disease represents a heterogeneous group of disorders leading to stroke and cognitive impairment. [pubmed.ncbi.nlm.nih.gov]

Keywords: CADASIL; CARASIL; HTRA1; small vessel disease; vascular dementia. © The Author (2015). [pubmed.ncbi.nlm.nih.gov]

Scn9a-Related Inherited Erythromelalgia

Brain. 2012 Sep. Abstract Patients with small fibre neuropathy typically manifest pain in distal extremities and severe autonomic dysfunction. [pubmed.ncbi.nlm.nih.gov]

[…] correlate with autonomic symptoms in small fibre neuropathy Chongyang Han et al. [pubmed.ncbi.nlm.nih.gov]

Affiliations PMID: 22826602 DOI: 10.1093/brain/aws187 Case Reports Functional profiles of SCN9A variants in dorsal root ganglion neurons and superior cervical ganglion neurons [pubmed.ncbi.nlm.nih.gov]

Idiopathic Basal Ganglia Calcification Type 1

Other Names Learn More: HPO ID 80%-99% of people have these symptoms Abnormality of neuronal migration 0002269 Cerebral calcification Abnormal deposits of calcium in the brain [rarediseases.info.nih.gov]

brain vessels 0002504 Chorea 0002072 Dense calcifications in the cerebellar dentate nucleus 0002461 Depressivity Depression 0000716 Dysarthria Difficulty articulating speech [rarediseases.info.nih.gov]

0002514 Hepatomegaly Enlarged liver 0002240 Intrauterine growth retardation Prenatal growth deficiency Prenatal growth retardation [ more ] 0001511 Microcephaly Abnormally small [rarediseases.info.nih.gov]

Cerebral Small Vessel Disease

Abstract Small vessel cerebrovascular disease (SVCD) is one of the most frequent vessel disorders in the aged brain. [ncbi.nlm.nih.gov]

CNS Metastasis

Results A 41-year old man diagnosed with metastatic adenocarcinoma of the lung with bilateral pulmonary nodules and 3 small brain micro metastases in April 2014. [jto.org]

[…] barrier removes small molecules from the CNS through efflux activity 4 The blood-brain barrier forms a CNS sanctuary for metastatic disease 4 The blood-barrier is reinforced [biooncology.com]

Case Presentation The patient in this case is a 70-year-old female diagnosed with multiple brain metastases from primary small-cell carcinoma of the lung. [hindawi.com]

Ophthalmoplegic Neuromuscular Disorder with Abnormal Mitochondria

Clinical, histopathological and genetic data from a small community living in the Reunion Island. [link.springer.com]

Brain 119: 295–308 CrossRef PubMed Google Scholar Fletcher S, Wilton SD, Howell JMcC (2000) Gene therapy and molecular approaches to the treatment of hereditary muscular disorders [link.springer.com]

Autosomal Recessive Myosin Storage Myopathy

Clinical, histopathological and genetic data from a small community living in the Reunion Island. [link.springer.com]

[…] vascular disease, is characterized by progressive degeneration of vascular smooth muscle cells (vSMCs) of small arteries in the brain, leading to recurrent ischemic stroke [academia.edu]

[…] defects mainly centred Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), a Notch3 dominant mutation-induced cerebral small [academia.edu]

Adenocarcinoma of the Lung Stage 1A

Non-small-cell lung cancer with brain metastasis at presentation. Clin Lung Cancer 2018; 19: e373-9. [ Links ] 28 Schouten LJ, Rutten J, Huveneers HA, Twijnstra A. [scielo.cl]

Adenocarcinoma of the Lung Stage 1B

Non-small-cell lung cancer with brain metastasis at presentation. Clin Lung Cancer 2018; 19: e373-9. [ Links ] 28 Schouten LJ, Rutten J, Huveneers HA, Twijnstra A. [scielo.cl]

Large-Cell Lung Cancer Stage 4

Non-small-cell lung cancer with brain metastasis at presentation. Clin Lung Cancer 2018; 19: e373-9. [ Links ] 28 Schouten LJ, Rutten J, Huveneers HA, Twijnstra A. [scielo.cl]

Microcephaly with Simplified Gyral Pattern

[…] head and a small brain. [ghr.nlm.nih.gov]

Autosomal recessive primary microcephaly (often shortened to MCPH, which stands for "microcephaly primary hereditary") is a condition in which infants are born with a very small [rarediseases.info.nih.gov]

As a result, affected infants have fewer nerve cells (neurons) than normal and are born with an unusually small brain. [ghr.nlm.nih.gov]

Brain Irradiation

When cancers that originate elsewhere cause small metastases in the brain, initial treatment should not routinely be followed by whole brain radiation therapy, because that [curetoday.com]

Download full article brain metastases prophylactic cranial irradiation small-cell lung cancer Previous article Next article Related Articles CancerWorld Plus Novel molecular [cancerworld.net]

BACKGROUND: Is Gamma Knife surgery alone as effective as surgery plus whole brain irradiation (WBRT) for patients with a single, small-sized brain metastasis? [ncbi.nlm.nih.gov]

Perisylvian Polymicrogyria with Cerebellar Hypoplasia and Arthrogryposis

In BPP, the grooves that develop during embryonic growth form improperly on both sides of the brain near the Sylvian fissure, resulting in an increased number of folds that [rarediseases.info.nih.gov]

[…] are unusually small.[1] Signs and symptoms typically become apparent at birth, infancy, or later during childhood, and may include partial paralysis of the face, tongue, [rarediseases.info.nih.gov]

Galloway-Mowat Syndrome Type 7

Detailed imaging of the brain such as magnetic resonance imaging (MRI) may reveal specific brain abnormalities seen in Galloway-Mowat syndrome such as a small cerebellum. [rarediseases.org]

Affected infants may have an abnormally small brain (microcephaly) at birth, or this can develop/progress as they get older. [rarediseases.org]

Several main symptoms associated with the disorder such as nephrotic syndrome, and a small brain (microcephaly) may be obvious at birth. [rarediseases.org]

Galloway-Mowat Syndrome Type 1

Detailed imaging of the brain such as magnetic resonance imaging (MRI) may reveal specific brain abnormalities seen in Galloway-Mowat syndrome such as a small cerebellum. [rarediseases.org]

Affected infants may have an abnormally small brain (microcephaly) at birth, or this can develop/progress as they get older. [rarediseases.org]

Several main symptoms associated with the disorder such as nephrotic syndrome, and a small brain (microcephaly) may be obvious at birth. [rarediseases.org]

Galloway-Mowat Syndrome Type 5

Detailed imaging of the brain such as magnetic resonance imaging (MRI) may reveal specific brain abnormalities seen in Galloway-Mowat syndrome such as a small cerebellum. [rarediseases.org]

Affected infants may have an abnormally small brain (microcephaly) at birth, or this can develop/progress as they get older. [rarediseases.org]

Several main symptoms associated with the disorder such as nephrotic syndrome, and a small brain (microcephaly) may be obvious at birth. [rarediseases.org]

Galloway-Mowat Syndrome Type 6

Detailed imaging of the brain such as magnetic resonance imaging (MRI) may reveal specific brain abnormalities seen in Galloway-Mowat syndrome such as a small cerebellum. [rarediseases.org]

Affected infants may have an abnormally small brain (microcephaly) at birth, or this can develop/progress as they get older. [rarediseases.org]

Several main symptoms associated with the disorder such as nephrotic syndrome, and a small brain (microcephaly) may be obvious at birth. [rarediseases.org]

COL4A1-Related Disorders

In most people, small vessel disease in the brain does not cause symptoms. Painful muscle cramps can occur and can develop before three years of age. [rarediseases.org]

Stroke subtype, vascular risk factors, and total MRI brain small-vessel disease burden. [frontiersin.org]

(E–H) Evaluation of blood–brain barrier integrity using immunoglobulin G (IgG) immunostaining. [ncbi.nlm.nih.gov]

Bilateral Polymicrogyria

Polymicrogyria (PMG) is a condition that affects the development of the human brain by multiple small gyri ( microgyri ) creating excessive folding of the brain leading to [en.wikipedia.org]

This malformation of the brain is a result of numerous small gyri taking over the surface of the brain that should otherwise be normally convoluted. [en.wikipedia.org]

The Greek roots of the name describe its salient feature: many [poly] small [micro] gyri (convolutions in the surface of the brain). [en.wikipedia.org]

Galloway-Mowat Syndrome Type 4

Detailed imaging of the brain such as magnetic resonance imaging (MRI) may reveal specific brain abnormalities seen in Galloway-Mowat syndrome such as a small cerebellum. [rarediseases.org]

Affected infants may have an abnormally small brain (microcephaly) at birth, or this can develop/progress as they get older. [rarediseases.org]

Several main symptoms associated with the disorder such as nephrotic syndrome, and a small brain (microcephaly) may be obvious at birth. [rarediseases.org]