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221 Possible Causes for Small Downslanting Palpebral Fissures

  • Gorlin-Chaudhry-Moss Syndrome

    Typical findings in the GCM syndrome are short stature, stocky body build, midface hypoplasia, small eyes, downslanting palpebral fissures, conductive hearing loss, highly[] […] or upslanted palpebral fissures, ectropion of lower eyelid, underdeveloped ala nasi, prominent columella, midface hypoplasia, and underdeveloped small ears with increased[] […] coronal craniosynostosis, facial dysmorphism (brachy/turricephaly, low anterior and posterior hairline, coarse hair, synophrys, depressed supraorbital ridges, short and downslanted[]

  • Acrootoocular Syndrome

    Clinical description Facial dysmorphism is characterized by small head, downslanting palpebral fissures, broad base of the nose, micrognathia and malformed ears.[] palpebral fissures epicanthal folds more Skeletal: delayed bone age Skeletal Feet: small feet widely spaced 1st-2nd toes zygodactyly short 3rd-4th toes protruding calcaneus[] Feet are small with a peculiar shape, wide space between toes 1 and 2 and syndactyly type 1 (see this term). The affected patients have no intellectual deficit.[]

  • Eye Muscle Disorder

    […] jaw (micrognathia); an unusually narrow, highly-arched roof of the mouth (palate); prominent front teeth (incisors); a high nasal bridge; downslanting eyelid folds (palpebral[] fissures); and/or malformed, protruding ears.[] […] characteristic craniofacial malformations may include an unusually small head (microcephaly); abnormal shortness of the groove in the middle of the upper lip (philtrum); a small[]

  • Marfan Syndrome

    Some people also have downslanting palpebral fissures, or eyes that appear to slant downward from the center outward.[] Many have a long face that is narrow, underdeveloped cheek bones, a small lower jaw that recedes, and a highly arched palate.[]

  • Coronary Cataract

    Other ophthalmologic signs observed in SLOS include blepharoptosis, epicanthal folds, strabismus, downslanting small palpebral fissures, mild exophthalmos, retinal pigment[]

  • Arterial Tortuosity Syndrome

    They generally present at birth with facial dysmorphism including beaked nose, blepharophimosis, hypertelorism, downslanting palpebral fissures and a small mouth with retrognathism[] A, Downslanting palpebral fissures and lax skin with prominent anterior axillary skin folds (arrow). B, Extreme laxity of skin fold is demonstrated. Figure 2.[] A small segment of the proximal descending thoracic aorta was narrow. ( Figures 2, 3A, and 3 B). Figure 1.[]

  • Autosomal Dominant Prognathism

    Persons with the condition have downslanting eyes ( antimongoloid palpebral fissures); absence of all or part of the lower lid; underdeveloped cheekbones that appear depressed[] ; a prominent nose, wide mouth, and small receding chin; underdeveloped, malformed, or prominent ears; and small tufts of hair in front of the ears.[]

  • Congenital Mandibular Hypoplasia

    […] jaw, low-set ears, round face, pre-auricular skin tags, hypertelorism, epicanthic folds, downslanting palpebral fissures) Can have congenital heart defect (esp PDA) AR inheritance[] […] of Ch5p Higher rate in girls than boys Feats: - Characteristic cat cry (disappears with age) - FTT and short stature - Facial dysmorphism (microcephaly, broad-based nose, small[]

  • Tel Hashomer Camptodactyly Syndrome

    downslanting palpebral fissures, hypoplastic nose with button tip and slitlike nares, small ''pursed'' mouth), profound sensorineural deafness, and ulnar deviations and contractures[] […] autosomal dominant disorder, described in one family to date, characterized by characteristic facial features (flat facial profile with normal calvarium, hypertelorism, small[]

  • Baller-Gerold Syndrome

    Affected infants may also have a prominent forehead; downslanting eyelid folds (palpebral fissures); small, malformed (dysplastic), low-set ears; and/or other craniofacial[] Affected infants may also have a prominent forehead; downslanting eyelid folds (palpebral fissures), small, malformed (dysplastic), low-set ears, and/or other craniofacial[]

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