Small Hand: Causes & Reasons

Possible Causes for Small Hand

X-Linked Syndromic Mental Retardation Type Armfield

Disease Ontology : 12 A syndromic X-linked intellectual disability characterized by intellectual disability, short stature, seizures, and small hands and feet and in some [malacards.org]

hands and feet and in some cases cleft palate or cataracts/glaucoma that has_material_basis_in variation in the chromosomal region Xq28. [informatics.jax.org]

hands and feet and in some cases cleft palate or cataracts/glaucoma that has_material_basis_in variation in the chromosomal region Xq28. https://www.ncbi.nlm.nih.gov/pubmed [zfin.org]

Sanjad-Sakati Syndrome

She had growth retardation: weight: 3 kg (-3SD), length:50 cm (-3SD), head circumference: 34 cm (-3SD), associated with dysmorphic features including small hands and feet, [ncbi.nlm.nih.gov]

All patients had severe intrauterine growth retardation, short stature, small hands and feet, blue sclera, deep-set eyes, microcephaly, persistent hypocalcaemia and hypoparathyroidism [apps.who.int]

Small hands with short and thin digits. Fig. 2. [karger.com]

Kenny-Caffey Syndrome Type 1

hands and feet. [ebi.ac.uk]

hands and feet. [ NCIT : C130992 ] Tree view Term mappings Preferred root terms All terms This is just here as a test because I lose it Term information Subsets gard_rare [ebi.ac.uk]

Prader-Willi Syndrome

hands and feet, mild dysmorphology, and behavior problems which can be severe. [curlie.org]

Down stated "Her feet and hands remained small and contrasted remarkably with the appendages they terminated. [whonamedit.com]

Description A syndrome characterised by pre and postnatal muscular hypotonia, thus giving an appearance of severe brain damage; obesity, low intelligence, small hands and [web.archive.org]

Rothmund-Thomson Syndrome

It is primarily a clinical diagnosis with manifestations that include poikiloderma, short stature, sparse hair, juvenile cataracts, small hands and feet, bone defects, photosensitivity [ncbi.nlm.nih.gov]

Besides this, less common aspects have been reported like alopecia, cataracts, short stature, musculoskeletal/bone defects or small hands, hypogonadism, abnormal teeth, dysplastic [ncbi.nlm.nih.gov]

hands and bone defects, sunlight sensitivity, hypogonadism, defective dentition, nail abnormality, hyperkeratosis, and mental retardation. [ncbi.nlm.nih.gov]

Andersen-Tawil Syndrome

hand Disproportionately small hands 0200055 Syncope Fainting spell 0001279 Toe syndactyly Fused toes Webbed toes [ more ] 0001770 Triangular face Face with broad temples [rarediseases.info.nih.gov]

Hypertelorism, small mandible, tooth crowding, and small hands were also observed. Table 1 provides a summary of the clinical characteristics of our patients. Table 1. [frontiersin.org]

Additional findings include small hands and feet, loose joints, and abnormal sideways curvature of the spine (scoliosis). [rarediseases.org]

Goldberg-Shprintzen Syndrome

Additional dysmorphic features may include maxillary hypoplasia, hypodontia, high arched palate, short neck, small hands, brachydactyly, fifth finger clinodactyly, fetal finger [orpha.net]

Scapuloperoneal Spinal Muscular Atrophy

hand Talipes equinovarus Abnormality of the musculature ... ... [familydiagnosis.com]

Clinical hallmarks of SPSMA are muscular atrophy of the shoulders, peroneal and small hand muscles resulting in distal weakness, predominantly of the lower limbs, and pectoral [orpha.net]

[…] anomalies clubfoot syndrome Short stature-Pierre Robin syndrome-cleft mandible-hand anomalies clubfoot syndrome Short stature-pituitary and cerebellar defects-small sella [orpha.net]

Developmental and Epileptic Encephalopathy Type 2

hands and feet. [mendelian.co]

]; Small hands; [Feet]; Small feet MUSCLE, SOFT TISSUE: Hypotonia NEUROLOGIC: [Central nervous system]; Seizures, infantile-onset; Hypsarrhythmia; Mental retardation, profound [genome.jp]

hands and feet, eye/vision anomalies, and global developmental delay. 6Q16 DELETION SYNDROME Is also known as del(6)(q16); monosomy 6q16; prader-willi-like syndrome due to [mendelian.co]

Aromatic L-Amino Acid Decarboxylase Deficiency

In addition, we observed that all patients (100.0%) had small hands and feet. [ncbi.nlm.nih.gov]

CONCLUSIONS: Patients with AADC deficiency in Taiwan have particular clinical manifestations of small hands and feet, which have rarely been mentioned in the literature. [ncbi.nlm.nih.gov]

X-Linked Syndromic Mental Retardation Type Wilson-Turner

[…] feet [ more ] 0001773 Short stature Decreased body height Small stature [ more ] 0004322 Small hand Disproportionately small hands 0200055 Tapered finger Tapered fingertips [rarediseases.info.nih.gov]

hands and feet). [encyclopedia2.thefreedictionary.com]

hand / acromicria - Small / hypoplastic / adherent / absent ear lobe - Spindle shaped fingers - Striae - Synophris / synophrys - Tapered fingers - Thick / bushy eyebrows [csbg.cnb.csic.es]

Helsmoortel-van der Aa Syndrome

The characteristic appearance includes short stature, a small rounded head flattened posteriorly, broadening of the neck, slanting eyes, a flattened nose, small broad hands [diapedia.org]

hands and ears, and that has been seen in one family to date. [findzebra.com]

hand　(小さな手)　[HP:0200055]　[15200] 　Stereotypy　(常同性)　[HP:0000733]　[02202] 　Strabismus　(斜視)　[HP:0000486]　[06610] 　Visual impairment　(視力障害)　[HP:0000505]　[06011] (UR-DBMS) 【一般 [syndromefinder.ncchd.go.jp]

Insulin-Like Growth Factor 1 Deficiency

Upon examination she was noted to have protruded forehead, thin hair, small hands and feet, and a saddle nose. [alliedacademies.org]

hands and feet, hypoplastic nails Tsezou et al ., 2000 [ 4 ] p12-p24 tandem - Brachycephaly - Psychomotor delay - High forehead, hypertelorism, epicanthus, deep-set eyes, [ncbi.nlm.nih.gov]

The individuals with LS show the characteristic features such as protruded forehead, saddle nose, blue sclera, and small hands and feet. [alliedacademies.org]

Congenital Disorder of Glycosylation Type 1E

hand Disproportionately small hands 0200055 Smooth philtrum 0000319 Splenomegaly Increased spleen size 0001744 Strabismus Cross-eyed Squint Squint eyes [ more ] 0000486 Telangiectasia [rarediseases.info.nih.gov]

hand Not very common - Between 30% and 50% cases High, narrow palate And 72 more phenotypes. [mendelian.co]

[…] activity 0004855 Respiratory distress Breathing difficulties Difficulty breathing [ more ] 0002098 Retinopathy Noninflammatory retina disease 0000488 Short palm 0004279 Small [rarediseases.info.nih.gov]

Onat Syndrome

hand Disproportionately small hands 0200055 Strabismus Cross-eyed Squint Squint eyes [ more ] 0000486 Subvalvular aortic stenosis Narrowing of blood vessel below aortic heart [rarediseases.info.nih.gov]

Central nervous system abnormalities, including small head size, intellectual disability, poor fine motor skills, or poor eye-hand coordination. [myhealth.alberta.ca]

[…] and Cerebellar Atrophy Growth Mental Deficiency Syndrome of Myhre GROWTH RETARDATION, INTELLECTUAL DEVELOPMENTAL DISORDER, HYPOTONIA, AND HEPATOPATHY Growth Retardation, Small [rgd.mcw.edu]

Autosomal Recessive Primary Microcephaly Type 13

Small hands and feet, hypogonadism. Fragile-X Syndrome Chromosomal Sex chromosome Progressively longer tandem repeats on the long arm of the X-chromosome. [kumc.edu]

Meier-Gorlin Syndrome

Small pits on the palms of the hand and soles of the feet are one of the major criteria of Gorlin syndrome. [gorlinsyndrome.org]

She played with toys, held objects in her hands, collected pyramids, and transferred small objects. [dovepress.com]

These include: An exam of the patient’s skin for basal cell carcinomas, pitting on hands and feet, areas of skin discoloration, and small cysts (milia) around the eyes and [gorlinsyndrome.org]

Geleophysic Dysplasia

Joint mobility was decreased, especially in the hands and elbows. He had very small hands and feet, and a voluminous inguinal hernia was present. [scielo.br]

We studied a 35-year-old woman with geleophysic dysplasia, with short stature, small hands and feet, limitation of joint mobility, mild skin thickening, cardiac valvular disease [ncbi.nlm.nih.gov]

The proposita's sister died of heart failure at 3 years and was reported by the mother to have been a tiny child with small hands. [ncbi.nlm.nih.gov]

Oculo-Palato-Cerebral Syndrome

hands and feet, cleft palate, joint hypermobility, developmental delay, and cerebral atrophy. [pubmed.ncbi.nlm.nih.gov]

hands and feet, joint laxity, and large ears with thick helices. [civilica.com]

including low-birth weight, microcephaly, cerebral atrophy, mild-to-severe developmental delay, cleft palate, Persistent hyperplastic primary vitreous, microphthalmia, small [sid.ir]

Cornelia De Lange Syndrome

hands to missing fingers or forearms Cleft palate Diaphragmatic hernias, vision and hearing problems, excessive body hair (hirsutism), heart defects, seizures and dental [chop.edu]

Many children have limb abnormalities, ranging from having small hands and particularly short thumbs in mild cases, to almost complete absence of the forearms in severe cases [contact.org.uk]

hands or feet, and missing fingers; • Seizures; • Gastroesophageal reflux; • Hearing loss; and • Vision abnormalities. [secure.ssa.gov]

Aicardi's Syndrome

Some girls also have skin problems, facial asymmetry, small hands, and an increased incidence of tumors. [childneurologyfoundation.org]

Autosomal-Recessive Robinow Syndrome

[…] stature [ more ] 0004322 Small hand Disproportionately small hands 0200055 Thin upper lip vermilion Thin upper lip 0000219 Upslanted palpebral fissure Upward slanting of [rarediseases.info.nih.gov]

hand ; Thin upper lip vermilion ; Thoracic hemivertebrae ; Thoracolumbar scoliosis ; Triangular mouth ; Umbilical hernia ; Vertebral fusion ; Wide anterior fontanel ; Wide [mousephenotype.org]

They may have small hands and feet, fused vertebrae, and genital defects. [wisegeek.com]

Acrodysostosis

Physical examination disclosed followings: weight 45 kg (0.50 SDS ), height 143.7 cm (−0.83 SDS ), synophrys, arched eyebrows, low-set ears, and small squared hands. [abstracts.eurospe.org]

[…] and legs with small hands and feet Short head, measured front to back Short height Small, upturned broad nose with flat bridge Distinct features of the face (short nose, open [medlineplus.gov]

Conclusion: Acrodysostosis should be kept in mind and appropriately evaluated when hormone resistance is detected in cases who presented with small hands and feet as well [abstracts.eurospe.org]

Dysidrosis

Dyshidrosis is a skin condition in which small, fluid-filled blisters appear on the hands and feet. [forums.phoenixrising.me]

Dyshidrosis, which is also known as ‘acute vesiculobullous hand eczema’, is a skin condition causing small blisters on either the hands or feet. [healthguidance.org]

[…] eczema," "pompholyx," and "podopompholyx") is a skin condition that is characterized by small blisters on the hands or feet. [symcat.com]

Aarskog-Scott Syndrome

Partial expression of the syndrome was confirmed in two of the three examined obligate female heterozygotes, who had short stature, small hands and feet, short neck, and a [ncbi.nlm.nih.gov]

[…] feet [ more ] 0001773 Short palm 0004279 Short stature Decreased body height Small stature [ more ] 0004322 Small hand Disproportionately small hands 0200055 Umbilical hernia [rarediseases.info.nih.gov]

Keywords Internal Medicine Metabolic Disease Short Stature Short Neck Small Hand These keywords were added by machine and not by the authors. [link.springer.com]

Female with more than three X Chromosomes

The patient had a characteristic round face, a low hairline, hypertelorism, epicanthus, a long philtrum, high-arched palate, short and webbed neck, small hands and feet, clinodactyly [scholars.northwestern.edu]

hands and feet. [doi.org]

Symptoms related to Pentasomy X include: Wide nasal bridge Intellectual disability Muscular hypotonia Cardiac septa abnormality Short foot Immune system symptoms Small hand [familydiagnosis.com]

Scn9a-Related Inherited Erythromelalgia

Small nerve fibres, small hands and small feet: a new syndrome of pain, dysautonomia and acromesomelia in a kindred with a novel NaV1.7 mutation. [pubmed.ncbi.nlm.nih.gov]

Congenital Disorder of Deglycosylation

Syndromic Moyamoya Disease

First published in 1986 under the editorial direction of Dr. Henry J.M. Barnett, Stroke: Pathophysiology, Diagnosis, and Management continues to provide the dependable, current answers you need to effectively combat the increasing incidence of this disease. Dr. J.P. Mohr, together with new associate editors Philip A.[…] [books.google.com]

Brachydactyly Type E2

ABSTRACT BACKGROUND: Autosomal-dominant brachydactyly type E is a congenital abnormality characterized by small hands and feet, which is a consequence of shortened metacarpals [pesquisa.bvsalud.org]