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632 Possible Causes for Small Palpebral Fissures

  • Chromosome 4q32.1-q32.2 Triplication Syndrome

    fissures epicanthal folds small palpebral fissures Head And Neck Nose: wide nasal bridge short nose Head And Neck Ears: low-set ears small ears malformed ears squared-off[malacards.org] fissures Epicanthus Frontal bossing Macrocephaly Microretrognathia Short nose Short philtrum Small palpebral fissure Abnormality of the abdomen Aganglionic megacolon Constipation[familydiagnosis.com] The three sons share with their mother the following facial features: long midface, myopathic face, wide nasal bridge, short nose, short palpebral fissures, and low set, small[ashg.org]

  • Pseudoaminopterin Syndrome

    […] jaw Small lower jaw [ more ] 0000347 Muscular hypotonia Low or weak muscle tone 0001252 Narrow forehead Decreased width of the forehead 0000341 Narrow palpebral fissure Small[rarediseases.info.nih.gov] It is characterized by skull (craniosynostosis and poorly mineralized cranial vault), dysmorphic (ocular hypertelorism, palpebral fissure anomalies, micrognathiacleft lip[malacards.org] The fetal alcohol syndrome is characterized by growth deficiency of prenatal onset, mild to moderate microcephaly, short palpebral fissures, mental deficiency, and fine motor[rrnursingschool.biz]

  • Autosomal Recessive Cutis Laxa Type 1B

    Child had dysmorphism in the form of sagging cheeks, maxillary hypoplasia, prognathism, posteriorly placed large and low set ears, hypertelorism, down slanting palpebral fissures[idoj.in] Such features include downward slanting of the opening between the eyelids (down slanting palpebral fissures), a broad, flat bridge of the nose, abnormally large nostrils[rarediseases.org] , wide open anterior fontanelle, medial epicanthal folds, depressed nose, long philtrum, and small mouth [Figure 1] a.[idoj.in]

  • Carpenter-Waziri Syndrome

    Facial characteristics include medial flair of the eyebrows, exotropia, ptosis, small palpebral fissures, maxillary hypoplasia, thick alae nasi, open mouth with arched palate[oxfordmedicine.com] Find this resource: (p. 147) Differential Matrix Syndrome Microcephaly Skeletal Manifestations Spasticity Comments Miles-Carpenter Short stature, ptosis, small palpebral fissures[oxfordmedicine.com] Facial asymmetry, bitemporal narrowing, and small teeth with irregular placement may be present. Ear size and architecture is not remarkable.[oxfordmedicine.com]

  • RAPADILINO Syndrome

    The 4 year old has talipes equinovarus, bilateral radial reduction defects, small palpebral fissures, small mouth, and skin changes.[digitalcommons.hsc.unt.edu] Additional findings were absence of thumbs, dislocation of joints, unusual facies (long face with narrow palpebral fissures, long slender nose, small chin, and unusual ears[humpath.com] Symptoms and Signs Patients with Rapadilino syndrome exhibit craniofacial anomalies, more commonly in the form of a long face, long slender nose, narrow palpebral fissures[dianamossop.com]

  • Immuno-Osseous Dysplasia

    The patients have a triangular face, broad nasal bridge, bulbous nose tip, small palpebral fissures, short neck, long upper lip, and low hairline.[ncbi.nlm.nih.gov] palpebral fissures, long upper lip and low hairline.[scholars.duke.edu] […] patients have intrauterine growth retardation, short stature with short neck and trunk, peculiar clinical phenotype: triangular face, broad nasal bridge, bulbous nasal tip, small[scholars.duke.edu]

  • Weaver Syndrome

    fissures, small palpebral fissures, strabismus, ptosis, broad nasal root, long philtrum, large and dysmorphic ears, micrognathia and highly arched palate.[atlasgeneticsoncology.org] […] or downslanting palpebral fissures.[karger.com] Craniofacial: macrocephaly, flat occiput, redundant nuchal skin folds, broad forehead with frontal bossing, thin scalp hair, hypertelorism, upslanting or downslanting palpebral[atlasgeneticsoncology.org]

  • Autosomal Dominant Progressive External Ophthalmoplegia

    We prefer to simultaneously recess the lower lid upward to maintain a small palpebral fissure centralized over the pupil.[centrallakesclinic.biz]

  • Blepharophimosis-Epicanthus Inversus-Ptosis Syndrome

    Definition A disorder characterized by eyelid dysplasia, small palpebral fissures, drooping eyelids and a skin fold curving in the mediolateral direction, inferior to the[uniprot.org] palpebral fissures (blepharophimosis), drooping eyelids (ptosis) and a skin fold arising from the lower eyelid (epicanthus inversus).[hmg.oxfordjournals.org] Patients experience a combination of congenital eyelid anomalies: small palpebral fissures, ptosis, telecanthus, and epicanthus inversus.[bmcmedgenet.biomedcentral.com]

  • Branchio-Oculo-Facial Syndrome

    On clinical examination, he presented growth retardation, epicanthal folds, small palpebral fissures, telecanthus, broadened nasal bridge, lip pseudocleft, micrognathia, dysplastic[ncbi.nlm.nih.gov] Our initial examination at age 5 months (Figs. 1,2) showed a partial unilateral cleft lip, high-arched palate, apparently low-set flat ears, small upward slanting palpebral[documents.tips] fissures with lacrimal duct obstruction, broad nose with a broad nasal root, and denudation of the cervical skin (Fig. 3).[documents.tips]

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