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81 Possible Causes for Small Platelet Size

  • Wiskott Aldrich Syndrome

    The Wiskott-Aldrich syndrome (WAS) is an X-linked recessive immune deficiency disorder characterized by thrombocytopenia, small platelet size, eczema, recurrent infections[] Despite the heterogeneity of genetic and clinical findings, a correlation with small platelet size is routinely observed.[] A diagnosis of Wiskott-Aldrich syndrome should be considered in any male infant who presents with early onset thrombocytopenia despite an absence of small platelet size, a[]

  • Platelet Storage Pool Deficiency

    Mol Genet Metab. 2017 Mar;120(3):288-294. doi: 10.1016/j.ymgme.2016.12.006. Epub 2016 Dec 18. Author information 1 Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, United States; Division of Genetics and Metabolism, Children's National Health System, Washington,[…][]

  • Infarction

    This clot might break free and begin to travel as a solid mass which blocks local blood vessels (especially small sized ones like capillaries).[] In fact, after an injury the platelets and fibrin form a clot to prevent blood loss.[]

  • Pernicious Anemia

    The number of platelets in the blood. Platelets are small cells that are involved in blood clotting. Red blood cell size.[]

  • Purpura

    This can create purple spots on the skin that range in size from small dots to large patches.[] Sometimes, low platelet levels can cause excessive bruising and bleeding. Platelets are the cells that help your blood clot.[]

  • Leukoerythroblastic Anemia

    Thrombocytopenia is associated with small size of platelets.(2) HbF% in children Fetal haemoglobin (HbF) should be measured pre-transfusion in children as this is an important[] […] reticulocytopenia, and macrocytosis is commonly seen.(2) Blood film examination To exclude other differentials look should for the presence of dysplastic neutrophils , abnormal platelets[]

  • Esophageal Varices

    Univariate analysis revealed significant differences between the grade of spleen, blood parameters, platelet count, international normalized ratio, serum albumin, spleen size[] RESULTS: 69% patients had small and 31% had large varices.[]

  • Aplastic Anemia

    The number of platelets in the blood. Platelets are small cell fragments that are involved in blood clotting. Red blood cell size.[]

  • Autosomal Dominant Macrothrombocytopenia

    Platelet size Disease OMIM Inheritance Gene Features Small Wiskott-Aldrich syndrome 301000 X WAS Immunodeficiency X-linked thrombocytopenia 313900 X WAS No immunodeficiency[] FYB thrombocytopenia na AR FYB Activated platelets Normal ANKRD26 thrombocytopenia 188000 AD ANKRD26 Predisposition to hematological malignancy Platelet disorder, familial[]

  • Primary Myelofibrosis

    Small doses of radiation to the spleen can also be given to reduce its size. This usually provides temporary relief for about 3 to 6 months.[] This sometimes happens because the spleen is destroying blood cells, particularly platelets, at a very fast rate.[]

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