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818 Possible Causes for Small Platelets

  • Wiskott Aldrich Syndrome

    A 7-month-old Korean boy presented with recurrent bloody diarrhea, eczema, and persistent thrombocytopenia with small platelets.[ncbi.nlm.nih.gov] Despite the heterogeneity of genetic and clinical findings, a correlation with small platelet size is routinely observed.[ncbi.nlm.nih.gov] platelet, and eczematoid dermatitis.[ncbi.nlm.nih.gov]

  • Idiopathic Pulmonary Fibrosis

    Finally, in 2014, pirfenidone, a compound with broad antifibrotic, anti-inflammatory and antioxidant properties and nintedanib, an orally available, small-molecule tyrosine[doai.io] […] kinase inhibitor with selectivity for vascular endothelial growth factor, platelet-derived growth factor and fibroblast growth factor receptors, have shown to significantly[doai.io]

  • Inherited Platelet Disorder

    Inherited Platelet Disorder Platelets are small cells that circulate in the blood.[hacacares.org] […] count and morphology – decreased number and abnormal platelets (small) Gray-platelet syndrome (alpha granule deficiency) Platelet count – decreased number Peripheral smear[arupconsult.com] Blood platelets are small cell fragments that help people stop bleeding after blood vessels are damaged.[clinicaltrials.gov]

  • Gray Platelet Syndrome

    Platelet count was decreased (33-150 X 10(9)/1) and small platelets were increased in platelet volume distribution. Bleeding time was prolonged on most occasions.[ncbi.nlm.nih.gov] At day 12 of culture, megakaryocytes from the patients with GPS contained some small alpha-granules labeled for Fg and vWF identical to those found in mature platelets.[ncbi.nlm.nih.gov] It is characterized by very small platelets (most platelet function disorders have normal to large platelets).[verywell.com]

  • Aspirin-induced Platelet Defect

    […] count and morphology – decreased number and abnormal platelets (small) Gray-platelet syndrome (alpha granule deficiency) Platelet count – decreased number Peripheral smear[arupconsult.com] A previous history of massive aspirin ingestion makes such a coagulopathy a serious consideration, but the platelet defect may occur with small doses of aspirin.[jhu.pure.elsevier.com] The fever, renal failure and neurologic features are due to platelet plugging of small vessels causing ischemia.[quizlet.com]

  • Thrombotic Thrombocytopenic Purpura

    […] results in the formation of small platelet clots called thrombi.[en.wikipedia.org] platelet aggregates.[ncbi.nlm.nih.gov] Thrombotic thrombocytopenic purpura (TTP), acquired is a blood disorder characterized by low platelets (i.e., thrombocytopenia ), small areas of bleeding under the skin (i.e[rarediseases.info.nih.gov]

  • Autosomal Dominant Thrombocytopenia 5

    Small platelets. Eczema X-linked thrombocytopenia (XLT) WAS (Xp11) Exon2 X-L Mild immunodeficiency. Defective WAS protein.[ufrgs.br] A small whole blood clot or very small fibrin clots in the EDTA anticoagulated specimen will usually be associated with clumping of platelets on the slide, and with a false[labcorp.com] When your blood has a low number of platelets—the small, disc-shaped cells that bind together when recognizing damaged blood vessels—the condition is called thrombocytopenia[pdsa.org]

  • Thrombocytopenia

    It may result in easy bruising and excessive bleeding from wounds or bleeding in mucous membranes and other tissues A condition in which there is an abnormally small number[icd9data.com] Definition (NCI) A condition in which there is an abnormally small number of platelets in the circulating blood.[fpnotebook.com] […] of platelets in the circulating blood A decrease in the number of platelets in the blood that may result in easy bruising and excessive bleeding from wounds or bleeding in[icd9data.com]

  • Atypical Hemolytic-Uremic Syndrome with Thrombomodulin Anomaly

    Small platelets. Eczema X-linked thrombocytopenia (XLT) WAS (Xp11) Exon2 X-L Mild immunodeficiency. Defective WAS protein.[ufrgs.br] When factor H is deficient or inactive, there is the potential for damage to the small vessels in the kidneys with secondary injury to red blood cells and platelets.[rarediseases.org] Half normal amount of vWF antigen and similarly decreased activity in the Ristocetin cofactor test vonWillebrand Deficiency Type IIA - Functional defect, multimers are too small[quizlet.com]

  • Increased Platelet Destruction

    Platelets are relatively small, irregularly shaped cells of our blood. They are required to maintain the integrity of our blood vessel walls and for blood to clot.[itpwalk.org] When your blood has a low number of platelets—the small, disc-shaped cells that bind together when recognizing damaged blood vessels—the condition is called thrombocytopenia[pdsa.org] […] an abnormally small number of platelets is present in the circulating blood.[medical-dictionary.thefreedictionary.com]

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