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979 Possible Causes for Small Platelets

  • Wiskott Aldrich Syndrome

    Despite the heterogeneity of genetic and clinical findings, a correlation with small platelet size is routinely observed.[ncbi.nlm.nih.gov] A 7-month-old Korean boy presented with recurrent bloody diarrhea, eczema, and persistent thrombocytopenia with small platelets.[ncbi.nlm.nih.gov] platelet, and eczematoid dermatitis.[ncbi.nlm.nih.gov]

  • Klinefelter Syndrome

    platelet, and eczematoid dermatitis.[ncbi.nlm.nih.gov] […] is a rare X-linked recessive disorder characterized by primary progressive T cell immunodeficiency, impaired antipolysaccharide antibody response, thrombocytopenia with small[ncbi.nlm.nih.gov]

  • Portal Vein Thrombosis

    Larger platelets, compared to small ones, increase platelet adhesion and aggregation, and present a higher thrombotic activity.[ncbi.nlm.nih.gov] Mean platelet volume (MPV) is an early marker of platelet activation.[ncbi.nlm.nih.gov]

  • Cerebral Thrombosis

    These findings suggest that a combination of enhanced platelet aggregation and hypertension increases the risk of small deep infarctions accompanied by mild stenotic changes[ncbi.nlm.nih.gov] Many patients of this group had persistent hypertension and small deep infarctions.[ncbi.nlm.nih.gov] Platelet aggregation was also measured in 20 hypertensive control subjects without stroke. Four of them (20%) showed enhanced aggregation.[ncbi.nlm.nih.gov]

  • Vascular Disease

    Platelet-derived microvesicles (pMVs) are small, heterogeneous vesicles released from platelet membranes as a result of activation.[ncbi.nlm.nih.gov]

  • Tricyclic Antidepressant

    Serotonin is a neurotransmitter present in the brain, small intestines, platelets, etc.[wako-chem.co.jp]

  • Ghosal Syndrome

    […] count and morphology – decreased number and abnormal platelets (small) Gray-platelet syndrome (alpha granule deficiency) Platelet count – decreased number Peripheral smear[arupconsult.com] – macrothrombocytopenia with neutrophilic inclusions ( MYH9 disorders) May-Hegglin anomaly, Sebastian syndrome, Fechtner syndrome, Epstein syndrome Thrombocytopenia with small[arupconsult.com] Cytoskeletal protein defect FLNA Wide spectrum disorder – skeletal, cardiac, gastrointestinal dysfunction Wiskott-Aldrich syndrome Cytoskeletal protein defect with decreased small[arupconsult.com]

  • Congenital Deficiency in Alpha-fetoprotein

    4) Maternal cousins, uncles or nephews with small platelets and thrombocytopenia Probable Male patient with congenital thrombocytopenia (less than 70,000 platelets/mm3),[esid.org] […] diseases 5) Lymphoma, leukemia or brain tumor Possible Male patient with thrombocytopenia (less than 70,000 platelets/mm3) and small platelets; or a male patient splenectomized[esid.org] small platelets and at least one of the following: 1) Eczema 2) Abnormal antibody response to polysaccharide antigens 3) Recurrent bacterial or viral infections 4) Autoimmune[esid.org]

  • Immunodeficiency due to Defective Expression of HLA Class 1

    4) Maternal cousins, uncles or nephews with small platelets and thrombocytopenia Probable Male patient with congenital thrombocytopenia (less than 70,000 platelets/mm3),[esid.org] […] diseases 5) Lymphoma, leukemia or brain tumor Possible Male patient with thrombocytopenia (less than 70,000 platelets/mm3) and small platelets; or a male patient splenectomized[esid.org] small platelets and at least one of the following: 1) Eczema 2) Abnormal antibody response to polysaccharide antigens 3) Recurrent bacterial or viral infections 4) Autoimmune[esid.org]

  • Immunodeficiency by Defective Expression of HLA Class 2

    4) Maternal cousins, uncles or nephews with small platelets and thrombocytopenia Probable Male patient with congenital thrombocytopenia (less than 70,000 platelets/mm3),[esid.org] […] diseases 5) Lymphoma, leukemia or brain tumor Possible Male patient with thrombocytopenia (less than 70,000 platelets/mm3) and small platelets; or a male patient splenectomized[esid.org] small platelets and at least one of the following: 1) Eczema 2) Abnormal antibody response to polysaccharide antigens 3) Recurrent bacterial or viral infections 4) Autoimmune[esid.org]

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