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27 Possible Causes for Small Testicular Volume, Tall Stature, Weight Gain

  • Klinefelter Syndrome

    gain, especially on the stomach or trunk tiredness and fatigue small penis disproportionately long arms and legs compared to the length of the body taller than average height[betterhealth.vic.gov.au] They concluded that the decline in serum testosterone may be related to the small testicular volume and Leydig cell loss near the scars after the procedures.[web.archive.org] These patients usually present with tall stature. We report a case of KS with short stature due to growth hormone deficiency.[ncbi.nlm.nih.gov]

  • Hypogonadotropic Hypogonadism

    gain or weight loss) Long-term (chronic) medical diseases, including chronic inflammation or infections Drug use, such as heroin or use or abuse of prescription opiate medicines[medlineplus.gov] Cryptorchid or maldescended testes and small testicular volume are clinical hallmarks of congenital hypogonadotropic hypogonadism (CHH) [ 1 ].[ijpeonline.biomedcentral.com] In addition the boy developed delay of puberty, bone age, and closure of the epiphyseal lines of long bones with tall stature.[ncbi.nlm.nih.gov]

  • Hypogonadism

    stature, especially if the legs are disproportionately long, gynecomastia, small or soft testes, and a eunuchoid body habitus) Considerations in the physical examination[emedicine.medscape.com] […] testes – volume typically 3 Lack of secondary sexual characteristics Most common cause is Klinefelter syndrome Postpubertal hypogonadism Sexual – decreased libido, erectile[arupconsult.com] gain or weight loss) Long-term (chronic) medical diseases, including chronic inflammation or infections Drug use, such as heroin or use or abuse of prescription opiate medicines[medlineplus.gov]

  • Klinefelter's Syndrome with XY/XXY Mosaic

    gain Can increase energy and sex drive and lower cholesterol levels Can stimulate bone mineralization and prevent loss of bone mass which can lead to osteoporosis Testosterone[en.wikibooks.org] These features would include first and foremost small firm testes (low testicular volume), tall slender body habitus, and in some cases breast enlargement (gynecomastia) and[dermatologyadvisor.com] stature with eunuchoid features, and psychosocial morbidity. 1 3 How common is Klinefelter’s syndrome?[bmj.com]

  • ROHHAD Syndrome

    Children with ROHHAD typically present after 1.5 years of age with rapid weight gain as the initial sign.[ncbi.nlm.nih.gov] […] infants but treatment with recombinant human FSH at age of 5-8 years seems to be less effectiv regarding increasing of the testicular volume and plasmatic levels of antimullerian[mafiadoc.com] IGF-1 levels are higher in morbid obesity and these cases are often tall.[ncbi.nlm.nih.gov]

  • 48,XXXY Syndrome

    It was later discontinued due to weight gain.[childhood-developmental-disorders.imedpub.com] Testicular volume is typically less than 10 ml in postpubertal 47,XXY individuals [ 5 ].[ojrd.biomedcentral.com] While often compared with 47,XXY/Klinefelter syndrome because of shared features including tall stature and hypergonadotropic hypogonadism, 48,XXYY, 48,XXXY and 49,XXXXY syndromes[unboundmedicine.com]

  • 48,XXYY Syndrome

    It has similarities to 47, XXY Klinefelter's syndrome, with tall stature, micro-orchidism, hypergonadotropic hypogonadism and infertility in males.[ncbi.nlm.nih.gov] In puberty and adult life, the main clinical characteristic that differentiates KS syndrome from X fragile syndrome is testicular volume, which is small in the first and big[scielo.br] It was later discontinued due to weight gain.[childhood-developmental-disorders.imedpub.com]

  • XXXXY Syndrome

    In acutely ill children, synbiotics have been linked to greater weight gain and fewer bacterial illnesses after antibiotics are ended.[livingnaturallyonline.com] Testicular volume is typically less than 10 ml in postpubertal 47,XXY individuals [ 5 ].[ojrd.com] While often compared with 47,XXY/Klinefelter syndrome because of shared features including tall stature and hypergonadotropic hypogonadism, 48,XXYY, 48,XXXY and 49,XXXXY syndromes[genetic.org]

  • Gonadotropic Pituitary Adenoma

    Signs and symptoms of excess GH In children (gigantism): Abnormally rapid growth Very tall stature Painful joints Excessive sweating.[innerbody.com] volume (no detailed data was presented). [6] Our patient had a normal testicular size with loss of libido.[neurologyindia.com] Too much of this hormone causes weight gain, particularly in the body’s trunk.[cancer.net]

  • Hypogonadotropic Hypogonadism Type 21

    Rapid weight gain continues into adulthood; stature remains short and may be caused by growth hormone deficiency.[merckmanuals.com] Cryptorchid or maldescended testes and small testicular volume are clinical hallmarks of congenital hypogonadotropic hypogonadism (CHH) [ 1 ].[ijpeonline.biomedcentral.com] They tend to have tall stature and mild motor and language developmental problems. Testosterone levels are normal.[endocrine-abstracts.org]

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