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139 Possible Causes for Smooth Pursuit Abnormalities

  • Chronic Alcoholism

    smooth pursuit eye movements, in saccadic inhibition during antisaccade tasks, and in prepulse inhibition, suggesting disturbed attention modulation and abnormal patterns[] Alcoholic patients display: (1) high beta and theta power in the resting electroencephalogram, suggesting hyperarousal of their central nervous system; (2) abnormalities in[]

  • Ataxia Telangiectasia

    Major oculomotor findings were fixation abnormalities (6/15), saccadic impairment (15/15), and abnormal smooth pursuit (14/15).[] Fifteen AT patients (mean age 12 years and 4 months) underwent a neurovisual evaluation, particularly focused on oculomotor functions (fixation, smooth pursuit, saccades,[] […] and abnormal ocular movements).[]

  • Barre-Lieou Syndrome

    Hildingsson et al. 5 have proposed dysfunction of the proprioceptive system of the cervicocranial region as an explanation for visual tracking (smooth pursuit) abnormalities[]

  • Lateral Medullary Syndrome

    These abnormalities include signs of dysfunction of ocular alignment (skew deviation, ocular tilt reaction, and environmental tilt), various types of nystagmus, smooth pursuit[] Axial FLAIR MRI of this patient, showing the hyperintensity in the right lateral medulla Abnormalities of ocular tracking eye movements (e.g. smooth pursuit and VOR cancellation[] […] and gaze-holding abnormalities (eye deviation, ipsipulsion or lateropulsion, and impaired contralateral pursuit), and saccadic abnormalities (ipsipulsion and torsipulsion[]

  • Sclerosteosis Type 2

    Growth delay Enlarged fossa interpeduncularis Abnormality of ocular smooth pursuit Thickened superior cerebellar peduncle Neonatal breathing dysregulation Brainstem dysplasia[] […] corpus callosum morphology Rotary nystagmus Agenesis of cerebellar vermis Communicating hydrocephalus Central apnea Impaired smooth pursuit Abnormal renal physiology Congenital[] […] hypoplasia Noncommunicating hydrocephalus Abnormality of cardiovascular system morphology Cognitive impairment Arthrogryposis multiplex congenita Ventriculomegaly Syndactyly[]

  • Enamel Hypoplasia Cataracts and Aqueductal Stenosis

    […] of ocular smooth pursuit Abnormality of the cerebral white matter Paraplegia Visual loss Hypergonadotropic hypogonadism Hypogonadism Elevated hepatic transaminase Intellectual[] […] pyramidal sign Difficulty walking Encephalopathy Peripheral demyelination Hyperreflexia Depressivity Impaired smooth pursuit Cerebral cortical atrophy Progressive Clonus[] pursuit Pectus excavatum Impaired proprioception Conjunctival telangiectasia Impaired distal vibration sensation Elevated alpha-fetoprotein Chronic axonal neuropathy Short[]

  • Alexander Disease

    Eye movement studies revealed square-wave jerks, gaze paretic nystagmus, rebound nystagmus, impaired smooth pursuit, impaired optokinetic nystagmus, and abnormal fixation[] A 51-year-old Chinese man presented with gaze-evoked nystagmus, impaired smooth pursuit and vestibular ocular reflex cancellation, and saccadic dysmetria, along with a family[] MRI revealed abnormalities of the medulla and cervical spinal cord typical of adult-onset Alexander disease, and genetic testing showed homozygosity for the p.D295N polymorphic[]

  • Cerebellar Ataxia

    pursuit impairment Abnormal vestibulo-ocular reflex With regards to the patients life quality and if severe, these conditions may result in the inability to perform routine[] […] muscles, the inability to rapidly perform alternating or targeted movements and to control motion ranges Instability of ocular alignment, saccadic intrusions and nystagmus, smooth[]

  • Spinocerebellar Ataxia Type 6

    Eye movement abnormalities such as gaze evoked and downbeat nystagmus, impaired smooth pursuit and abnormal vestibulo-ocular reflex are commonly seen in SCA6 patients.[] Takeichi et al (2000) reported that while ocular smooth pursuit is diminished, vestibular cancellation is normal. This may be a distinctive finding of this condition.[] Patients with prolonged courses exhibit dystonic postures, involuntary movements and abnormalities in tendon reflexes (Ikeuchi et al, 1997).[]

  • Autosomal Recessive Ataxia Type Beauce

    […] cerebellum morphology Neuronal loss in central nervous system Incoordination Progressive gait ataxia Abnormality of ocular smooth pursuit Impaired horizontal smooth pursuit[] Generalized hyperreflexia Abnormal pyramidal sign Juvenile onset Postural tremor Impaired smooth pursuit Gaze-evoked horizontal nystagmus Vertical supranuclear gaze palsy[] Delayed gross motor development Saccadic smooth pursuit Neurological speech impairment Spastic paraparesis Paraparesis Dysdiadochokinesis Pontocerebellar atrophy Sensory[]

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