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139 Possible Causes for Smooth Pursuit Abnormalities

  • Chronic Alcoholism

    smooth pursuit eye movements, in saccadic inhibition during antisaccade tasks, and in prepulse inhibition, suggesting disturbed attention modulation and abnormal patterns[ncbi.nlm.nih.gov] Alcoholic patients display: (1) high beta and theta power in the resting electroencephalogram, suggesting hyperarousal of their central nervous system; (2) abnormalities in[ncbi.nlm.nih.gov]

  • Ataxia Telangiectasia

    Major oculomotor findings were fixation abnormalities (6/15), saccadic impairment (15/15), and abnormal smooth pursuit (14/15).[ncbi.nlm.nih.gov] Fifteen AT patients (mean age 12 years and 4 months) underwent a neurovisual evaluation, particularly focused on oculomotor functions (fixation, smooth pursuit, saccades,[ncbi.nlm.nih.gov] […] and abnormal ocular movements).[ncbi.nlm.nih.gov]

  • Barre-Lieou Syndrome

    Hildingsson et al. 5 have proposed dysfunction of the proprioceptive system of the cervicocranial region as an explanation for visual tracking (smooth pursuit) abnormalities[chiroweb.com]

  • Lateral Medullary Syndrome

    These abnormalities include signs of dysfunction of ocular alignment (skew deviation, ocular tilt reaction, and environmental tilt), various types of nystagmus, smooth pursuit[ncbi.nlm.nih.gov] Axial FLAIR MRI of this patient, showing the hyperintensity in the right lateral medulla Abnormalities of ocular tracking eye movements (e.g. smooth pursuit and VOR cancellation[neuroophthalmology.ca] […] and gaze-holding abnormalities (eye deviation, ipsipulsion or lateropulsion, and impaired contralateral pursuit), and saccadic abnormalities (ipsipulsion and torsipulsion[ncbi.nlm.nih.gov]

  • Sclerosteosis Type 2

    Growth delay Enlarged fossa interpeduncularis Abnormality of ocular smooth pursuit Thickened superior cerebellar peduncle Neonatal breathing dysregulation Brainstem dysplasia[mendelian.co] […] corpus callosum morphology Rotary nystagmus Agenesis of cerebellar vermis Communicating hydrocephalus Central apnea Impaired smooth pursuit Abnormal renal physiology Congenital[mendelian.co] […] hypoplasia Noncommunicating hydrocephalus Abnormality of cardiovascular system morphology Cognitive impairment Arthrogryposis multiplex congenita Ventriculomegaly Syndactyly[mendelian.co]

  • Enamel Hypoplasia Cataracts and Aqueductal Stenosis

    […] of ocular smooth pursuit Abnormality of the cerebral white matter Paraplegia Visual loss Hypergonadotropic hypogonadism Hypogonadism Elevated hepatic transaminase Intellectual[mendelian.co] […] pyramidal sign Difficulty walking Encephalopathy Peripheral demyelination Hyperreflexia Depressivity Impaired smooth pursuit Cerebral cortical atrophy Progressive Clonus[mendelian.co] pursuit Pectus excavatum Impaired proprioception Conjunctival telangiectasia Impaired distal vibration sensation Elevated alpha-fetoprotein Chronic axonal neuropathy Short[mendelian.co]

  • Alexander Disease

    Eye movement studies revealed square-wave jerks, gaze paretic nystagmus, rebound nystagmus, impaired smooth pursuit, impaired optokinetic nystagmus, and abnormal fixation[ncbi.nlm.nih.gov] A 51-year-old Chinese man presented with gaze-evoked nystagmus, impaired smooth pursuit and vestibular ocular reflex cancellation, and saccadic dysmetria, along with a family[ncbi.nlm.nih.gov] MRI revealed abnormalities of the medulla and cervical spinal cord typical of adult-onset Alexander disease, and genetic testing showed homozygosity for the p.D295N polymorphic[ncbi.nlm.nih.gov]

  • Cerebellar Ataxia

    pursuit impairment Abnormal vestibulo-ocular reflex With regards to the patients life quality and if severe, these conditions may result in the inability to perform routine[symptoma.com] […] muscles, the inability to rapidly perform alternating or targeted movements and to control motion ranges Instability of ocular alignment, saccadic intrusions and nystagmus, smooth[symptoma.com]

  • Spinocerebellar Ataxia Type 6

    Eye movement abnormalities such as gaze evoked and downbeat nystagmus, impaired smooth pursuit and abnormal vestibulo-ocular reflex are commonly seen in SCA6 patients.[orpha.net] Takeichi et al (2000) reported that while ocular smooth pursuit is diminished, vestibular cancellation is normal. This may be a distinctive finding of this condition.[tchain.com] Patients with prolonged courses exhibit dystonic postures, involuntary movements and abnormalities in tendon reflexes (Ikeuchi et al, 1997).[tchain.com]

  • Autosomal Recessive Ataxia Type Beauce

    […] cerebellum morphology Neuronal loss in central nervous system Incoordination Progressive gait ataxia Abnormality of ocular smooth pursuit Impaired horizontal smooth pursuit[mendelian.co] Generalized hyperreflexia Abnormal pyramidal sign Juvenile onset Postural tremor Impaired smooth pursuit Gaze-evoked horizontal nystagmus Vertical supranuclear gaze palsy[mendelian.co] Delayed gross motor development Saccadic smooth pursuit Neurological speech impairment Spastic paraparesis Paraparesis Dysdiadochokinesis Pontocerebellar atrophy Sensory[mendelian.co]

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