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411 Possible Causes for Sole Thickening

  • Sjogren-Larsson Syndrome

    Her palms and soles were slightly thickened. A mild amount of scaling on the scalp also was present (Figure). Her nails were unaffected.[mdedge.com] The patient's skin finely desquamated until 2 weeks of age and then slightly thickened, especially in the flexural areas, palms, and soles.[mdedge.com] Desquamation, especially of the palms and soles, occurs in some cases. The face, hair, and nails usually are spared.[mdedge.com]

  • Skin Infection

    The sole of your foot can also become itchy, thickened and scaly. You might get blisters too.[bupa.co.uk] The soles appear scaly. Less commonly, small water bubbles or spots containing pus appear.[dermatology.org.sg] The toenails can also be affected and look unhealthy, with a yellowish discolouration and thickening seen under the nails.[dermatology.org.sg]

  • Congenital Alopecia

    The skin over the palms and soles showed progressive thickening, which led to mutilating deformities of the hands and fingers.[ncbi.nlm.nih.gov]

  • Left Atrial Hypertrophy

    Remarkably, an increased PTF-V 1 has often been associated with left atrial enlargement which is defined as a rather increased left atrial volume than a solely thickened left[degruyter.com] Hence, the presented approach to thicken the left atrial wall allows to draw conclusions in a much smaller study population compared to clinical studies.[degruyter.com] Although our virtual population of four patients was small compared to most in vivo studies, an in silico approach carries the advantage of solely altering specific anatomical[degruyter.com]

  • Etretinate

    Because of periosteal thickening of the tibia, presumably caused by etretinate, therapy was terminated one year after it began.[ncbi.nlm.nih.gov] Treatment with etretinate was effective for the palms and fingers, but resulted in no improvement of the keratoderma of the soles.[ncbi.nlm.nih.gov]

  • Mycosis

    Erythrodermic form: in the erythrodermic form, the skin becomes red, thickened, and sometimes peels and flakes. The palms and soles thicken and may crack.[encyclopedia.com]

  • Microcornea

    […] skin on palms * Thickened skin on soles Prevention - Microcornea- glaucoma- and absent frontal sinuses Not supplied.[checkorphan.org] […] skin on palms * Thickened skin on soles * Flat face * Round face * Impaired vision * Epicanthic folds * Skull abnormality Note that Microcornea - glaucoma - absent frontal[checkorphan.org] Microcornea - glaucoma - absent frontal sinuses includes the 11 symptoms listed below: * Glaucoma * Small corneas * Missing frontal sinuses * Bony outgrowths on palate * Thickened[checkorphan.org]

  • Acromegaly

    […] of the palms of the hands and soles of the feet.[novartis.com] "Living with Acromegaly Reset the Balance Improve Your Outlook" View and print brochure Symptoms and signs may include: Soft tissue thickening of the palms of the hands and[acromegaly.org] […] visual problems, enlargement of hands, feet, internal organs and/or facial features, oily skin and excessive sweating, sleep apnea, fatigue, joint pain, and soft tissue thickening[novartis.com]

  • Growth Hormone Deficiency

    Palmoplantar keratoderma (PPK) is a diverse group of disorders, characterized by thickening of the palms and soles, which are subdivided into focal or diffuse; it can be acquired[ncbi.nlm.nih.gov]

  • Pityriasis Rubra Pilaris

    The palms and soles thicken and have an orange colour. The nails may thicken and may be discoloured and sometimes shed.[skinsupport.org.uk] soles.[bad.org.uk] […] and soles.[skinsupport.org.uk]

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