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3 Possible Causes for Some Patients Develop Diabetes Mellitus as Adolescents

  • Metabolic Syndrome

    Hyperinsulinemia leads to development of widespread acanthosis nigricans, followed by onset of diabetes mellitus during adolescence 7, 8.[ncbi.nlm.nih.gov] Some patients develop extreme hypertriglyceridemia especially after the onset of insulin-resistant diabetes mellitus and are prone to recurrent attacks of acute pancreatitis[ncbi.nlm.nih.gov] Diabetes is generally ketosis-resistant.[ncbi.nlm.nih.gov]

  • Cystic Fibrosis

    Individuals with cystic fibrosis may be at risk for developing cystic fibrosis-related diabetes mellitus (CFRD).[rarediseases.org] CFRD may occur in some adolescents with cystic fibrosis, although the prevalence increases during adulthood, as the longer patients live with cystic fibrosis, the more likely[rarediseases.org] […] they are to develop CFRD.[rarediseases.org]

  • Lipodystrophy

    Hyperinsulinemia leads to development of widespread acanthosis nigricans, followed by onset of diabetes mellitus during adolescence 7, 8.[ncbi.nlm.nih.gov] Some patients develop extreme hypertriglyceridemia especially after the onset of insulin-resistant diabetes mellitus and are prone to recurrent attacks of acute pancreatitis[ncbi.nlm.nih.gov] Diabetes is generally ketosis-resistant.[ncbi.nlm.nih.gov]

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