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1,878 Possible Causes for Sparse, Abnormal Hair

  • Ectodermal Dysplasia

    PURPOSE: Anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) is characterized by hypohidrosis, dental abnormalities, sparse hair, and immunodeficiency.[ncbi.nlm.nih.gov] Abstract Hair abnormalities in ectodermal dysplasia may be difficult to identify.[ncbi.nlm.nih.gov] All had fine, slow-growing scalp hair and body hair and some had sparse eyebrows and short eyelashes. Nearly all showed decrease in sweating.[ncbi.nlm.nih.gov]

  • Netherton Syndrome

    The corneocyte surface areas correlated significantly with the rate of combined sparse and dense diffuse patterns of desmoglein 1.[ncbi.nlm.nih.gov] Netherton syndrome is an autosomal recessive disorder, characterized by ichthyosis, atopic manifestations, and hair shaft abnormalities (trichorrhexis invaginata).[ncbi.nlm.nih.gov] We report 2 children who presented since the first months of life cheek erythema followed by the appearance of sparse ILC lesions on the face, trunk and proximal extremities[ncbi.nlm.nih.gov]

  • Monilethrix

    We define the molecular basis of monilethrix in a Japanese patient who has had sparse and fragile scalp hairs since birth.[ncbi.nlm.nih.gov] Trichoscopy in genetic hair shaft abnormalities Abstract Background : Diagnosis of hair shaft abnormalities is based on light microscopic examination of more than 50 plucked[doi.org] Localized autosomal recessive hypotrichosis (LAH) is a recently defined disorder characterized by fragile, short, sparse hairs on the scalp, trunk, and extremities.[ncbi.nlm.nih.gov]

  • Rothmund Thomson Syndrome

    Rothmund-Thomson syndrome (RTS) is a rare autosomal recessive disorder mainly characterized by cutaneous poikiloderma, sparse hair, short stature and skeletal defects.[ncbi.nlm.nih.gov] Rothmund-Thomson syndrome (RTS) is a rare autosomal recessive disorder with clinical features consisting of poikiloderma, skeletal abnormalities, sparse hair, absent or scanty[ncbi.nlm.nih.gov] , sparse hair distribution, juvenile cataracts, and a predisposition to osteosarcoma.[ncbi.nlm.nih.gov]

  • Hidrotic Ectodermal Dysplasia

    sparse scalp hair 59 32 hallmark (90%) Very frequent (99-80%) HP:0002209 3 sparse axillary hair 59 32 frequent (33%) Frequent (79-30%) HP:0002215 4 absent eyebrow 59 32 hallmark[malacards.org] Moreover, hair abnormalities develop at birth, infancy, or childhood and include partial or complete hair loss on the scalp, axillary, and pubic regions.[symptoma.com] Sparse scalp hair and dysplastic nails are seen early in life.[en.wikipedia.org]

  • Menkes Disease

    A 6-month-old Thai male infant presented with seizure, global delayed development, hypotonia and sparse, short, lightly pigmented and kinky hair.[ncbi.nlm.nih.gov] Menkes disease is a rare X-linked recessive disorder of copper metabolism, characterised by progressive neurological degeneration, abnormal hair and connective tissue manifestations[ncbi.nlm.nih.gov] ;21) (q13.3;p11.1) karyotype presented with skin redundancy, especially in the neck, prominent occiput and micrognathia, and later developed hypotonia, hypopigmentation, sparse[ncbi.nlm.nih.gov]

  • Loose Anagen Syndrome

    People experiencing excessively unusual amounts of hair breakage may have an abnormality within the hair shafts.[hairfinder.com] The children studied had sparse hair that did not grow long and that pulled easily from the scalp.[ncbi.nlm.nih.gov] The typical patient is a child with sparse fine hair that can easily be pulled out.[ncbi.nlm.nih.gov]

  • Trichorhinophalangeal Syndrome

    The syndrome is characterised by sparse slow-growing hair, a bulbous pear-shaped nose, cone-shaped epiphyses and deformities of the interphalangeal joints resembling those[ncbi.nlm.nih.gov] Trichorhinophalangeal syndrome (TRPS) comprises a distinctive combination of hair, facial and bony abnormalities with variable expression.[ncbi.nlm.nih.gov] Patient's mother shared the same facial features, and presented sparse hair and small hands.[ncbi.nlm.nih.gov]

  • Rapp-Hodgkin Syndrome

    This syndrome is characterized by stiff sparse hair with the appearance of steel wool, sparse eyebrows and lashes, cleft palate, absence of lacrimal punctae, epiphora, a decreased[ncbi.nlm.nih.gov] […] of teeth, hair, nails and sweating.[ncbi.nlm.nih.gov] He had sparse, wiry, slow growing and uncombable hair, but no pili torti or pili canaliculi characteristic of RHS.[ncbi.nlm.nih.gov]

  • Cartilage Hair Hypoplasia

    The patient had the typical features of CHH, including sparse hair and metaphyseal abnormalities.[ncbi.nlm.nih.gov] Biopsy shows hypoplasia (underdevelopment) of cartilage to be the nature of the skeletal abnormality. The hair is unusually fine, sparse and light-colored.[medicinenet.com] Cartilage-hair hypoplasia (CHH) is a rare autosomal recessive skeletal dysplasia characterized by short stature, sparse hair, and a variable degree of immunodeficiency.[ncbi.nlm.nih.gov]

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