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1,878 Possible Causes for Sparse, Abnormal Hair

  • Ectodermal Dysplasia

    PURPOSE: Anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) is characterized by hypohidrosis, dental abnormalities, sparse hair, and immunodeficiency.[] Abstract Hair abnormalities in ectodermal dysplasia may be difficult to identify.[] All had fine, slow-growing scalp hair and body hair and some had sparse eyebrows and short eyelashes. Nearly all showed decrease in sweating.[]

  • Netherton Syndrome

    The corneocyte surface areas correlated significantly with the rate of combined sparse and dense diffuse patterns of desmoglein 1.[] Netherton syndrome is an autosomal recessive disorder, characterized by ichthyosis, atopic manifestations, and hair shaft abnormalities (trichorrhexis invaginata).[] We report 2 children who presented since the first months of life cheek erythema followed by the appearance of sparse ILC lesions on the face, trunk and proximal extremities[]

  • Monilethrix

    We define the molecular basis of monilethrix in a Japanese patient who has had sparse and fragile scalp hairs since birth.[] Trichoscopy in genetic hair shaft abnormalities Abstract Background : Diagnosis of hair shaft abnormalities is based on light microscopic examination of more than 50 plucked[] Localized autosomal recessive hypotrichosis (LAH) is a recently defined disorder characterized by fragile, short, sparse hairs on the scalp, trunk, and extremities.[]

  • Rothmund Thomson Syndrome

    Rothmund-Thomson syndrome (RTS) is a rare autosomal recessive disorder mainly characterized by cutaneous poikiloderma, sparse hair, short stature and skeletal defects.[] Rothmund-Thomson syndrome (RTS) is a rare autosomal recessive disorder with clinical features consisting of poikiloderma, skeletal abnormalities, sparse hair, absent or scanty[] , sparse hair distribution, juvenile cataracts, and a predisposition to osteosarcoma.[]

  • Hidrotic Ectodermal Dysplasia

    sparse scalp hair 59 32 hallmark (90%) Very frequent (99-80%) HP:0002209 3 sparse axillary hair 59 32 frequent (33%) Frequent (79-30%) HP:0002215 4 absent eyebrow 59 32 hallmark[] Moreover, hair abnormalities develop at birth, infancy, or childhood and include partial or complete hair loss on the scalp, axillary, and pubic regions.[] Sparse scalp hair and dysplastic nails are seen early in life.[]

  • Menkes Disease

    A 6-month-old Thai male infant presented with seizure, global delayed development, hypotonia and sparse, short, lightly pigmented and kinky hair.[] Menkes disease is a rare X-linked recessive disorder of copper metabolism, characterised by progressive neurological degeneration, abnormal hair and connective tissue manifestations[] ;21) (q13.3;p11.1) karyotype presented with skin redundancy, especially in the neck, prominent occiput and micrognathia, and later developed hypotonia, hypopigmentation, sparse[]

  • Loose Anagen Syndrome

    People experiencing excessively unusual amounts of hair breakage may have an abnormality within the hair shafts.[] The children studied had sparse hair that did not grow long and that pulled easily from the scalp.[] The typical patient is a child with sparse fine hair that can easily be pulled out.[]

  • Trichorhinophalangeal Syndrome

    The syndrome is characterised by sparse slow-growing hair, a bulbous pear-shaped nose, cone-shaped epiphyses and deformities of the interphalangeal joints resembling those[] Trichorhinophalangeal syndrome (TRPS) comprises a distinctive combination of hair, facial and bony abnormalities with variable expression.[] Patient's mother shared the same facial features, and presented sparse hair and small hands.[]

  • Rapp-Hodgkin Syndrome

    This syndrome is characterized by stiff sparse hair with the appearance of steel wool, sparse eyebrows and lashes, cleft palate, absence of lacrimal punctae, epiphora, a decreased[] […] of teeth, hair, nails and sweating.[] He had sparse, wiry, slow growing and uncombable hair, but no pili torti or pili canaliculi characteristic of RHS.[]

  • Cartilage Hair Hypoplasia

    The patient had the typical features of CHH, including sparse hair and metaphyseal abnormalities.[] Biopsy shows hypoplasia (underdevelopment) of cartilage to be the nature of the skeletal abnormality. The hair is unusually fine, sparse and light-colored.[] Cartilage-hair hypoplasia (CHH) is a rare autosomal recessive skeletal dysplasia characterized by short stature, sparse hair, and a variable degree of immunodeficiency.[]

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