Possible Causes for sparse to no eyebrows Rothmund-Thomson Syndrome […] and thin eyebrow Thin, sparse eyebrows 0000535 Sparse eyelashes Scant eyelashes Scanty eyelashes Thin eyelashes [ more ] 0000653 5%-29% of people have these symptoms Abnormal [rarediseases.info.nih.gov] They often have sparse scalp hair, eyebrows, and eyelashes. [dermaamin.com] Scoliosis Abnormal curving of the spine 0002650 Short philtrum 0000322 Small for gestational age Birth weight less than 10th percentile Low birth weight [ more ] 0001518 Sparse [rarediseases.info.nih.gov] Hidrotic Ectodermal Dysplasia Underdeveloped Thick, discolored Hair Fine, brittle, slow-growing Total balding (alopecia) Missing in spots for males Sparse eyelashes Sparse eyebrow Absent underarm hair [nfed.org] […] and thin eyebrow Thin, sparse eyebrows 0000535 Sparse eyelashes Scant eyelashes Scanty eyelashes Thin eyelashes [ more ] 0000653 5%-29% of people have these symptoms Abnormal [rarediseases.info.nih.gov] Sparse or absent eyebrows Sparse or absent eyelashes Diagnosing Fried Syndrome A physician can diagnose Fried syndrome on the basis of physical features. [nfed.org] Dubowitz Syndrome […] scalp hair Flexural areas eczema Delayed teeth eruption Dental caries Syndactyly of second toes Brachyclinodactyly of fifth fingers Hair is sparse on lateral eyebrows Syndactyly [syndrome.org] Affected individuals also tend to have sparse hair and eyebrows. [rarediseases.org] Lateral telecanthus Drooping upper eyelid Eyes are wide-set Blepharophimosis Prominent ears Epicanthal folds Dysplastic ears that is mild Lower jaw small Facial skin eczema Sparse [syndrome.org] Hypergonadotropic Hypogonadism - Partial Alopecia 60 Very frequent (99-80%) 42 sparse eyebrow 60 Frequent (79-30%) 43 absent gonadal tissue 60 Very frequent (99-80%) [malacards.org] eyebrows, absence of breast tissue, absent ovaries, mild-moderate dorsal kyphosis, thin upper lip and unilateral sensorioneural deafness in one of them. [ncbi.nlm.nih.gov] /absent eyelashes and eyebrows, mineralization defects of the skull, thin dysplastic clavicles, pulmonary hypoplasia, multiple joint contractures and an early neonatal lethal [ab-y-ss.com] Rapp-Hodgkin Syndrome He also had sparse eyelashes and eyebrows, and obstructed lacrimal puncta and epiphora. Bilateral bony external auditory canal stenosis led to hearing loss. [ncbi.nlm.nih.gov] […] by anhidrotic ectodermal dysplasia, cleft lip and palate, and accompanied by a characteristic facies (narrow nose and small mouth); wiry, slow-growing, uncombable hair; sparse [medical-dictionary.thefreedictionary.com] He had sparse, wiry, slow growing and uncombable hair, but no pili torti or pili canaliculi characteristic of RHS. [ncbi.nlm.nih.gov] Kaufman Oculocerebrofacial Syndrome […] and thin eyebrow Thin, sparse eyebrows 0000535 Ventricular septal defect Hole in heart wall separating two lower heart chambers 0001629 Ventriculomegaly 0002119 [rarediseases.info.nih.gov] […] and laterally broad eyebrows, preauricular tags, and micrognathia), mental retardation, and generalised hypotonia. [moh-it.pure.elsevier.com] 0004283 Optic disc pallor 0000543 Ovoid vertebral bodies 0003300 Short nose Decreased length of nose Shortened nose [ more ] 0003196 Single transverse palmar crease 0000954 Sparse [rarediseases.info.nih.gov] Wiedemann-Rautenstrauch Syndrome She had prominent scalp veins, facial dysmorphism sparse eyebrows and hair and significant developmental delay. [ashg.org] sparse hair, sparse eyebrows, sparse eyelashes, prominent scalp veins, entropion, greatly widened anterior fontanelles, malar hypoplasia, natal teeth, and beaking of the [accessanesthesiology.mhmedical.com] […] scalp hair, decreased eyebrows and eyelashes, and micrognathia. [orpha.net] Atrichia with Papular Lesions Sparse hairs over the eyebrows and eyelashes were present [ Figure 1 ]. [ncbi.nlm.nih.gov] He had sparse hairs over the eyebrow and eyelashes. He complained of multiple, raised lesions over the face and upper trunk for three years. [ncbi.nlm.nih.gov] Multiple papular lesions over the face with alopecia of scalp, sparse hair over eyebrows (a) Histopathology of a papule over the back revealed multiple mid-dermal cysts containing [ncbi.nlm.nih.gov] Tricho-rhino-phalangeal Syndrome […] and thin eyebrow Thin, sparse eyebrows 0000535 Sparse eyelashes Scant eyelashes Scanty eyelashes Thin eyelashes [ more ] 0000653 Triangular face Face with broad temples and [rarediseases.info.nih.gov] Abstract We describe a 5-year-old girl with features resembling Trichorhinophalangeal syndrome, type I (sparse scalp hair, bushy eyebrows, bulbous nose, long philtrum, cone-shaped [ncbi.nlm.nih.gov] These syndromes have characteristic facial abnormalities such as sparse and slow-growing scalp hair, laterally sparse eyebrows, bulbous pear-shaped nose, elongated and flat [ncbi.nlm.nih.gov] Microcephalic Osteodysplastic Primordial Dwarfism Type II […] and thin eyebrow ; Sparse eyelashes ; Sparse scalp hair ; Stillbirth ; Tetralogy of Fallot Associated Genes RNU4ATAC (Withdrawn symbols: RNU4ATAC1, U4atac ) Mouse Orthologs [mousephenotype.org] Sparse hair and eyebrows, dry skin, short limbs and dislocation of the hips and elbows are other common features. [orpha.net] The patient had intrauterine growth retardation, sparse scalp hair, sparse eyebrows and eyelashes, high arched palate, micrognathia, low set ears, short neck, clenched fists [ajol.info] Odonto-Onycho-Dermal Dysplasia […] and thin eyebrow Thin, sparse eyebrows 0000535 Sparse body hair 0002231 Sparse scalp hair Scalp hair, thinning Sparse, thin scalp hair sparse-absent scalp hair [ more ] 0002209 [rarediseases.info.nih.gov] Some STHAG4 patients manifest mild features of ectodermal dysplasia, including sparse hair, sparse eyebrows, short eyelashes, abnormalities of the nails, sweating anomalies [genecards.org] Some patients may have dry, thin hair and sparse eyebrows, and may have a smooth tongue with missing taste buds. [sema4genomics.com] Kabuki Syndrome Facial features include long palpebral fissures with eversion of the lower lateral eyelid, sparse and arched eyebrows, depressed nasal tip, and large prominent earlobes. [dnatesting.uchicago.edu] […] and thin eyebrow Thin, sparse eyebrows 0000535 Strabismus Cross-eyed Squint Squint eyes [ more ] 0000486 Ventricular septal defect Hole in heart wall separating two lower [rarediseases.info.nih.gov] […] lateral eyebrows, prominent ears, and persistent fetal fingertip pads. [ncbi.nlm.nih.gov] Chromosome 19q13.11 Deletion Syndrome […] hair 0008070 Sparse lateral eyebrow Limited hair on end of eyebrow 0005338 Sparse or absent eyelashes 0200102 Supernumerary nipple Accessory nipple 0002558 Thin skin 0000963 [rarediseases.info.nih.gov] eyebrows in patient 1 and by sparse eyebrows and teeth anomalies in patient 2. [nature.com] […] hair, long face, high frontal hair line, sparse eyebrows and eyelashes, hypoplastic alae nasi, and low-set ears; and (d) shawl scrotum. [molecularcytogenetics.biomedcentral.com] Nestor-Guillermo Progeria Syndrome […] and thin eyebrow ; Sparse eyelashes ; Spotty hyperpigmentation ; Wide cranial sutures Associated Genes BANF1 (Withdrawn symbols: BAF ) Mouse Orthologs Banf1 (Withdrawn symbols [mousephenotype.org] […] and thin eyebrow Thin, sparse eyebrows 0000535 Sparse eyelashes Scant eyelashes Scanty eyelashes Thin eyelashes [ more ] 0000653 Spotty hyperpigmentation Spotty increased [rarediseases.info.nih.gov] […] and thin eyebrow Very Common - Between 80% and 100% cases Insulin resistance Very Common - Between 80% and 100% cases Other less frequent symptoms Patients with BANF1 gene [mendelian.co] Hallermann-Streiff Syndrome His ophthalmic features included sparse eyelashes and eyebrows, microphthalmia, nystagmus, lower lid entropion in the right eye, and upper lid entropion with blepharoptosis [ncbi.nlm.nih.gov] […] and thin eyebrow Thin, sparse eyebrows 0000535 Sparse eyelashes Scant eyelashes Scanty eyelashes Thin eyelashes [ more ] 0000653 Telecanthus Corners of eye widely separated [rarediseases.info.nih.gov] […] and thin eyebrow Sparse eyelashes Telecanthus Underdeveloped nasal alae Visual impairment Occasionally present symptoms in 5-29% of the cases: Abdominal situs inversus Abnormality [dovemed.com] Pallister-Killian Syndrome […] and thin eyebrow Thin, sparse eyebrows 0000535 Sparse hair 0008070 Thick upper lip vermilion Full upper lip Increased volume of upper lip Plump upper lip Prominent upper [rarediseases.info.nih.gov] […] nervous system: Extreme hypotonia at birth Epileptic seizures Mental developmental delays Hearing loss, lack of speech development Issues related to the face and skull: Sparse [dovemed.com] Newborns and children also have a specific phenotype, characterized by facial dimorphism: "coarse" facies, high forehead, sparse lashes and eyebrows, shallow supraorbital [symptoma.com] Netherton Syndrome […] and thin eyebrow Thin, sparse eyebrows 0000535 Sparse eyelashes Scant eyelashes Scanty eyelashes Thin eyelashes [ more ] 0000653 1%-4% of people have these symptoms Intestinal [rarediseases.info.nih.gov] […] location Displaced kidney [ more ] 0000086 Erythroderma 0001019 Hydronephrosis 0000126 Short stature Decreased body height Small stature [ more ] 0004322 Skin rash 0000988 Sparse [rarediseases.info.nih.gov] Diffuse Palmoplantar Keratoderma The eyelashes are short and sparse, and the eyebrows as well as axillary and pubic hair are also sparse or absent (1), as in our case. [ncbi.nlm.nih.gov] Scalp hair is sparse, fine, lightly pigmented, and grows slowly with scant or absent eyebrows. The eyelashes may be normal, sparse, or completely absent. [idoj.in] The hair from the beard, eyebrows, eyelashes, moustaches, and pubic and axillary regions was very sparse to nearly absent (Figure 2 a, b, c). [ncbi.nlm.nih.gov] Rombo Syndrome Sparse eyebrows * Absent eyebrows * Whitish-yellow skin bumps * Areas of red skin Causes Absent eyebrows -,Chronic skin infection ,Decreased body hair Skin nodules [checkorphan.org] On examination, all the three terminal hair-bearing areas before puberty were affected: Sparse and lightly pigmented hair over scalp, absence of eyebrows and eyelashes [Figure [ijtrichology.com] Symptoms * Sparse eyelashes * Absent eyelashes * Carcinoma * Skin telangiectasia * Thin skin * Epithelioma * Decreased body hair * Skin nodules * Chronic skin infection * [checkorphan.org] Goldberg-Shprintzen Syndrome One of the described patients had sparse scalp hair, a sloping forehead, sparse eyebrows, broad nasal bridge, large ears, pointed chin, ventricular septal defect, hypospadias [diseaseinfosearch.org] The patient had mild but progressive microcephaly (-2 SD) and dysmorphic facial features, including sloping forehead, hypertelorism, sparse eyebrows, depressed nasal bridge [omim.org] […] and thin eyebrow Thin, sparse eyebrows 0000535 Sparse scalp hair Reduced/lack of hair on scalp Scalp hair, thinning Sparse, thin scalp hair sparse-absent scalp hair [ more [rarediseases.info.nih.gov] Growth Failure Macrocephaly, coarse face, large mouth with thick lips or macroglossia, frizzy and sparse hair, strabismus, epicanthic fold, thick eyebrows, low nasal bridge and low set ears [amhsr.org] Macrocephaly, coarse face, curly, sparse hair, thick eyebrows, eye (epicantal folds), nose (short bulbous nose, depressed nasal bridge), mouth (large mouth, thick lips, macroglossia [amhsr.org] Hypothyroidism Full sparse outer 1/3 Hair Thin, sparse on extremities Coarse and sparse Hair loss Sometimes Common Nails Thin, brittle Normal to thick Peri-orbital Tissue Sunken Puffy Skin [drlam.com] Symptoms, signs and additional investigation findings in hypothyroidism Organ system Symptoms and signs Appearance Puffy and pale facies Dry, brittle hair Sparse eyebrows [racgp.org.au] […] lower Low 90s to 98.6 Temp regulation fluctuating and exaggerated Steady Mental Function Mental Function Brain Fog Slow thinking Depression Sometimes Frequent Physical Looks Eyebrows [drlam.com] Pili Torti Symptoms - Pili torti Sparse eyebrows Absent eyebrows Sparse eyelashes Absent eyelashes Twisted hair shaft Causes - Pili torti The common cause of pili torti is genetics, [checkorphan.org] Symptoms Sparse eyebrows Absent eyebrows Sparse eyelashes Absent eyelashes Twisted hair shaft Causes The common cause of pili torti is genetics, and usually develops in early [checkorphan.org] Clinical examination showed dry, lustreless, fragile, and brittle hair of scalp and sparse hairs involving eyebrows [Figure 1]. [ijtrichology.com] Ichthyosis Vulgaris Patient’s hair was dry, sparse and eyebrows were scanty ( Figure 1 ). There were no nail abnormalities. [omicsonline.org] Microtia […] or arched eyebrows. [ncbi.nlm.nih.gov] […] scalp, choanal atresia, esophageal atresia (EA), tracheo-esophageal fistula (TEF), persistent vitelline duct, athelia/hypothelia, and subtle facial dysmorphisms including sparse [ncbi.nlm.nih.gov] Cerebro-Facio-Thoracic Dysplasia […] and thin eyebrow Thin, sparse eyebrows 0000535 Sparse eyelashes Scant eyelashes Scanty eyelashes Thin eyelashes [ more ] 0000653 Supernumerary nipple Accessory nipple 0002558 [rarediseases.info.nih.gov] curly and/or slow-growing hair, lack of eyebrows and eyelashes, abnormal skin lesions varying from severe atopic dermatitis to hyperkeratosis/ichthyosis-like lesions Hypotonia [en.wikibooks.org] Synophrys Monobrow Unibrow [ more ] 0000664 Thick eyebrow Bushy eyebrows Dense eyebrow Heavy eyebrows Prominent eyebrows Thick eyebrows [ more ] 0000574 Upslanted palpebral [rarediseases.info.nih.gov] Autosomal Recessive Nail Dysplasia Sparse or absent eyebrows Sparse or absent eyelashes Diagnosing Fried Syndrome A physician can diagnose Fried syndrome on the basis of physical features. [nfed.org] At present we can identify dry scaly skin; fine sparse and brittle hair, eyebrows, and eyelashes, hypodontia, nail dystrophy, hypohidrosis, and athelia, with deficient hearing [omicsonline.org] (a) A female child with sparse scalp hair and absent eyebrows and eyelashes with an old man appearance. [e-ijd.org] Trichotillomania Bare patches where hair has been pulled out including sparse or missing eyebrows and/or eyelashes. Playing with pulled out hair. [glennmillermd.com] Physical Effects Bald spots Patchy hair Inconsistent hair regrowth Sparse or missing eyebrows Uneven hairline Infections Blepharitis Psychological Effects Shame Embarrassment [trichstop.com] Patients can also present with sparse eyebrows or eyelashes. [aocd.org] Micrognathism eyebrows and/or eyelashes. [diki.pl] Characteristic features may include microcephaly, ear abnormalities, anteverted nares, midfacial hypoplasia, tented upper lip and small jaw (micrognathia), sparse or absent [diki.pl] […] lateral eyebrows; Strabismus; Microphthalmia; Hyperopia; Megalocornea; Iris hypoplasia; Iris coloboma; Tapetoretinal degeneration; [Nose]; Broad nasal tip; Broad nasal bridge [findzebra.com] Hashimoto Thyroiditis coarse, and dry hair Coarse, dry, and thickened skin Hand tingling or pain (carpal tunnel syndrome) Slow pulse Muscle cramps Joint pain Sides of eyebrows thin or fall out [uclahealth.org] […] expressions Tiredness and lack of energy (fatigue) Not being able to handle cold Hoarse voice Slow speech Droopy eyelids Puffy and swollen face Weight gain Constipation Sparse [uclahealth.org]
