Spastic Gait: Causes & Reasons

Possible Causes for Spastic Gait

Autosomal Dominant Spastic Paraplegia Type 31

[…] characterized by a pure phenotype of proximal weakness of the lower extremities with spastic gait and brisk reflexes, with a bimodal age of onset of either childhood or adulthood [orpha.net]

[…] with spastic gait and brisk reflexes, with a bimodal age of onset of either childhood or adulthood (>30 years). [rarediseases.info.nih.gov]

Homepage Rare diseases Search Search for a rare disease Autosomal dominant spastic paraplegia type 31 Disease definition A rare type of hereditary spastic paraplegia usually [orpha.net]

X-Linked Spastic Paraplegia Type 2

There are a number of references which give descriptions of a spastic gait - here's part of one I like: When a person has a spastic gait, his legs are typically weak and abnormally [hspjourney.blogspot.com]

The disease spectrum for Pelizaeus-Merzbacher disease and spastic paraplegia type 2 is extraordinarily broad, ranging from a spastic gait in the pure form of spastic paraplegia [ncbi.nlm.nih.gov]

SPG2 is characterized by spastic gait and hyperreflexia. [malacards.org]

Autosomal Recessive Spastic Paraplegia Type 32

[…] type 2, Juvenile (Spastic gait) Amyotrophic lateral sclerosis type 2 (Spastic gait) Ataxia (Spastic gait) Autosomal dominant inheritance ... ... [familydiagnosis.com]

[…] paraplegia 32 HP:0001258 3 cerebellar atrophy 32 HP:0001272 4 pes cavus 32 HP:0001761 5 cerebral atrophy 32 HP:0002059 6 spastic gait 32 HP:0002064 7 hypoplasia of the corpus [malacards.org]

[…] paraplegia 60 Frequent (79-30%) 14 spastic gait 33 HP:0002064 15 cerebellar cortical atrophy 60 Frequent (79-30%) 16 abnormality of the pons 60 Frequent (79-30%) 17 lower [malacards.org]

Autosomal Dominant Spastic Paraplegia Type 10

gait Spastic walk 0002064 Spastic paraplegia 0001258 Urinary bladder sphincter dysfunction 0002839 Urinary incontinence Loss of bladder control 0000020 Showing of 38 | Last [rarediseases.info.nih.gov]

[…] paraparetic gait 0031958 Spastic/hyperactive bladder 0005340 Urinary urgency Overactive bladder 0000012 5%-29% of people have these symptoms Ataxia 0001251 Dupuytren contracture [rarediseases.info.nih.gov]

[…] the lower limbs Diminished vibratory sensation in the legs [ more ] 0002166 Knee clonus 0011449 Pes cavus High-arched foot 0001761 Progressive Worsens with time 0003676 Spastic [rarediseases.info.nih.gov]

Autosomal Recessive Spastic Paraplegia Type 46

Gait (SPG) Locus OMIM Number Protein (genetic locus if protein is unknown) Clinical Syndrome Autosomal dominant HSP SPG3A 182600 Atlastin Uncomplicated HSP: symptoms usually [mhmedical.com]

0002061 Optic atrophy 0000648 Paraplegia Leg paralysis 0010550 Progressive Worsens with time 0003676 Spastic gait Spastic walk 0002064 Urinary incontinence Loss of bladder [rarediseases.info.nih.gov]

SPG4 is characterized by insidiously progressive bilateral lower-limb gait spasticity. [centogene.com]

Autosomal Dominant Spastic Paraplegia Type 36

[…] by an onset in childhood or adulthood of progressive spastic paraplegia (with spastic gait, spasticity, lower limb weakness, pes cavus and urinary urgency) associated with [orpha.net]

SPG4 is characterized by insidiously progressive bilateral lower-limb gait spasticity. [centogene.com]

Walking pattern described as “spastic gait” occurs in which the following elements are present, each to variable degree in different individuals: a) heel strike is shifted [rarediseases.org]

Autosomal Dominant Spastic Paraplegia Type 6

0002061 Progressive Worsens with time 0003676 Seizures Seizure 0001250 Spastic gait Spastic walk 0002064 Urinary bladder sphincter dysfunction 0002839 Urinary urgency Overactive [rarediseases.info.nih.gov]

Showing of 26 | 80%-99% of people have these symptoms Babinski sign 0003487 Gait disturbance Abnormal gait Abnormal walk Impaired gait [ more ] 0001288 Impaired vibratory [rarediseases.info.nih.gov]

[…] vibration sense Decreased vibratory sense Diminished vibratory sense Impaired vibratory sense [ more ] 0002495 Lower limb hyperreflexia Overactive lower leg reflex 0002395 Spastic [rarediseases.info.nih.gov]

Autosomal Recessive Spastic Paraplegia Type 26

Background: Hereditary spastic paraplegias (HSP) are degenerative diseases of upper motor neurons characterized by a progressive spastic gait disorder which are phenotypically [mdsabstracts.org]

gait Spastic walk 0002064 Spastic paraplegia 0001258 Toe walking Toe-walking 0040083 Showing of 37 | Last updated: 12/1/2018 If you need medical advice, you can look for [rarediseases.info.nih.gov]

SPG4 is characterized by insidiously progressive bilateral lower-limb gait spasticity. [centogene.com]

Hereditary Spastic Paraplegia

For many subjects with an ATL1 mutation, spastic gait begins in early childhood and does not significantly worsen, even over many years; such cases resemble spastic diplegic [ncbi.nlm.nih.gov]

Characteristic clinical features comprise progressive spastic gait, cognitive impairment, and ataxia. [ncbi.nlm.nih.gov]

Hereditary spastic paraplegias (HSPs) are genetically driven disorders with the hallmark of progressive spastic gait disturbance. [ncbi.nlm.nih.gov]

Autosomal Recessive Spastic Paraplegia Type 44

SPG4 is characterized by insidiously progressive bilateral lower-limb gait spasticity. [centogene.com]

Objective assessment of gait after intrathecal baclofen in hereditary spastic paraplegia. [en.wikipedia.org]

Furthermore, type II form of HSP usually evolves more rapidly. [12] Summary of genotypes The genes are designated SPG (Spastic gait gene). [ipfs.io]

Autosomal Dominant Spastic Paraplegia Type 37

[…] by a childhood- to adulthood-onset of slowly progressive spastic gait, extensor plantar responses, brisk tendon reflexes in arms and legs, decreased vibration sense at ankles [orpha.net]

spastic paraplegia characterized by a slowly progressive and relatively benign spastic paraplegia presenting in adulthood with spastic gait, lower limb hyperreflexia, extensor [mendelian.co]

He described “a pure spastic movement disorder of the legs” in 2 brothers who developed a spastic gait at the ages of 37 and 56 years. [medlink.com]

Autosomal Dominant Spastic Paraplegia Type 42

[…] by slowly progressive spastic paraplegia of lower extremities with an age of onset ranging from childhood to adulthood and patients presenting with spastic gait, increased [orpha.net]

HSP3A usually develops in early childhood with more than 80% of affected individuals developing spastic gait before 10 years of age. [flybase.org]

SPG4 is characterized by insidiously progressive bilateral lower-limb gait spasticity. [centogene.com]

Autosomal Dominant Spastic Paraplegia Type 4

The clinical phenotype includes asymptomatic patients, mildly affected individuals with spastic gait but able to walk independently, and severely affected patients who were [link.springer.com]

gait Spastic walk 0002064 Spastic paraplegia 0001258 Urinary bladder sphincter dysfunction 0002839 Urinary incontinence Loss of bladder control 0000020 Urinary urgency Overactive [rarediseases.info.nih.gov]

He described “a pure spastic movement disorder of the legs” in 2 brothers who developed a spastic gait at the ages of 37 and 56 years. [medlink.com]

Autosomal Recessive Spastic Paraplegia Type 48

SPG4 is characterized by insidiously progressive bilateral lower-limb gait spasticity. [centogene.com]

Objective assessment of gait after intrathecal baclofen in hereditary spastic paraplegia. [en.wikipedia.org]

Furthermore, type II form of HSP usually evolves more rapidly. [12] Summary of genotypes The genes are designated SPG (Spastic gait gene). [ipfs.io]

Autosomal Dominant Spastic Paraplegia Type 41

spastic gait and mild urinary compromise. [orpha.net]

Objective assessment of gait after intrathecal baclofen in hereditary spastic paraplegia. [en.wikipedia.org]

Furthermore, type II form of HSP usually evolves more rapidly. [12] Summary of genotypes The genes are designated SPG (Spastic gait gene). [ipfs.io]

Autosomal Recessive Spastic Paraplegia Type 49

SPG4 is characterized by insidiously progressive bilateral lower-limb gait spasticity. [centogene.com]

Walking pattern described as “spastic gait” occurs in which the following elements are present, each to variable degree in different individuals: a) heel strike is shifted [rarediseases.org]

Objective assessment of gait after intrathecal baclofen in hereditary spastic paraplegia. [en.wikipedia.org]

Autosomal Dominant Spastic Paraplegia Type 19

He described “a pure spastic movement disorder of the legs” in 2 brothers who developed a spastic gait at the ages of 37 and 56 years. [medlink.com]

SPG4 is characterized by insidiously progressive bilateral lower-limb gait spasticity. [centogene.com]

Walking pattern described as “spastic gait” occurs in which the following elements are present, each to variable degree in different individuals: a) heel strike is shifted [rarediseases.org]

X-Linked Spastic Paraplegia Type 34

SPG4 is characterized by insidiously progressive bilateral lower-limb gait spasticity. [centogene.com]

Objective assessment of gait after intrathecal baclofen in hereditary spastic paraplegia. [en.wikipedia.org]

Hereditary spastic paraplegia Specialty Neurology Hereditary spastic paraplegia (HSP) is a group of inherited diseases whose main feature is a progressive gait disorder. [en.wikipedia.org]

Autosomal Recessive Spastic Paraplegia Type 7

Children with very early onset may have relatively non-progressive spastic gait. ~ 6 yrs, 2 – 50 yrs AD Uncomplicated/ Complicated Atlastin (SPG3A) DNA Sequencing Mainly pure [1pdf.net]

SPG4 is characterized by insidiously progressive bilateral lower-limb gait spasticity. [centogene.com]

Objective assessment of gait after intrathecal baclofen in hereditary spastic paraplegia. [en.wikipedia.org]

Autosomal Dominant Spastic Paraplegia Type 17

gait Spastic walk 0002064 5%-29% of people have these symptoms Abnormal motor nerve conduction velocity 0040131 Ankle weakness 0031374 Distal sensory impairment Decreased [rarediseases.info.nih.gov]

SPG4 is characterized by insidiously progressive bilateral lower-limb gait spasticity. [centogene.com]

gait Spastic walk 0002064 Spastic paraplegia 0001258 Urinary incontinence Loss of bladder control 0000020 Variable expressivity 0003828 Showing of 39 | Last updated: 5/1/ [rarediseases.info.nih.gov]

Autosomal Recessive Spastic Paraplegia Type 20

They all had some difficulties in walking, with clumsy, mildly spastic gait. [cags.org.ae]

gait Spastic walk 0002064 Speech apraxia 0011098 1%-4% of people have these symptoms Ataxia 0001251 Bilateral vestibular Schwannoma 0009589 Cafe-au-lait spot 0000957 Cortical [rarediseases.info.nih.gov]

Objective assessment of gait after intrathecal baclofen in hereditary spastic paraplegia. [en.wikipedia.org]

Autosomal Dominant Spastic Paraplegia Type 8

SPG4 is characterized by insidiously progressive bilateral lower-limb gait spasticity. [centogene.com]

Walking pattern described as “spastic gait” occurs in which the following elements are present, each to variable degree in different individuals: a) heel strike is shifted [rarediseases.org]

Objective assessment of gait after intrathecal baclofen in hereditary spastic paraplegia. [en.wikipedia.org]

Autosomal Dominant Spastic Paraplegia Type 13

[…] ankle clonus spastic gait lower limb hyperreflexia extensor plantar responses more Neurologic Peripheral Nervous System: decreased vibration sense in the lower limbs Genitourinary [malacards.org]

SPG4 is characterized by insidiously progressive bilateral lower-limb gait spasticity. [centogene.com]

Walking pattern described as “spastic gait” occurs in which the following elements are present, each to variable degree in different individuals: a) heel strike is shifted [rarediseases.org]

Autosomal Recessive Spastic Paraplegia Type 14

SPG4 is characterized by insidiously progressive bilateral lower-limb gait spasticity. [centogene.com]

Walking pattern described as “spastic gait” occurs in which the following elements are present, each to variable degree in different individuals: a) heel strike is shifted [rarediseases.org]

Objective assessment of gait after intrathecal baclofen in hereditary spastic paraplegia. [en.wikipedia.org]

Autosomal Dominant Spastic Paraplegia Type 12

He described “a pure spastic movement disorder of the legs” in 2 brothers who developed a spastic gait at the ages of 37 and 56 years. [medlink.com]

SPG4 is characterized by insidiously progressive bilateral lower-limb gait spasticity. [centogene.com]

Walking pattern described as “spastic gait” occurs in which the following elements are present, each to variable degree in different individuals: a) heel strike is shifted [rarediseases.org]

Autosomal Recessive Spastic Paraplegia Type 45

[…] paraplegia type 45 is a rare, pure or complex form of hereditary spastic paraplegia characterized by onset in infancy of progressive lower limb spasticity, abnormal gait, [mendelian.co]

Objective assessment of gait after intrathecal baclofen in hereditary spastic paraplegia. [en.wikipedia.org]

SPG4 is characterized by insidiously progressive bilateral lower-limb gait spasticity. [centogene.com]

Juvenile Primary Lateral Sclerosis

gait Spastic walk 0002064 Spastic tetraparesis 0001285 30%-79% of people have these symptoms Dysphagia Poor swallowing Swallowing difficulties Swallowing difficulty [ more [rarediseases.info.nih.gov]

Gait gene locus; AD= Autosomal dominant; AR= Autosomal recessive; HSP60= heat shock protein 60 (mitochondrial Chaperonin); KIF5A= kinesin heavy chain; NIPA1= non imprinted [wiki.iop.kcl.ac.uk]

JALS is characterized by onset during childhood (mean age of onset is 6.5 years), spasticity of facial muscles, uncontrolled laughter, spastic dysarthria, spastic gait, inconstant [cmm.ucsd.edu]

Amyotrophic Lateral Sclerosis Type 5

Patients then develop motor neuron degeneration leading to facial muscle spasticity, spastic dysarthria, and spastic gait. [orpha.net]

dysarthria, and a spastic gait (manner of walking). [rarediseases.info.nih.gov]

In case of ALS5, however, pyramidal signs such as an increase of muscle tone, spastic gait, and hyperreflexia with extensor plantar responses appear late in the course of [symptoma.com]

Pallidopyramidal Syndrome

Symptoms * Pyramidal signs * Parkinson disease * Tremor * Rigidity * Hyperreflexia * Spastic muscle tone * Gait disturbance * Bradykinesia * Dysarthria * Dysphagia Diagnosis [checkorphan.org]

He walked with a stooped posture and had a spastic gait with frequent freezing and marked postural instability (UPDRS Grade 3). [casereports.in]

There were no intention tremors, coordination in lower limbs could not be tested due to spasticity. [casereports.in]

Cerebral Palsy

BACKGROUND: Previous researchers reported that popliteal angle did not correlate well with knee angle during gait in individuals with spastic cerebral palsy (CP). [ncbi.nlm.nih.gov]

Abstract To compare medial gastrocnemius muscle-tendon structure, gait propulsive forces, and ankle joint gait kinetics between typically developing children and those with [ncbi.nlm.nih.gov]

CASE DESCRIPTION: Three children with spastic cerebral palsy demonstrate the effect on gait when the blocks attributable to the orthoses were removed. [ncbi.nlm.nih.gov]