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2,167 Possible Causes for Spastic Paraplegia

  • Cervical Spondylosis

    ., metastatic tumors), subacute combined degeneration of the spinal cord (vitamin B 12 deficiency), hereditary spastic paraplegia, normal pressure hydrocephalus and spinal[aafp.org] Severe cases of cervical spinal canal stenosis can also cause paraplegia, and significant loss of function also rarely, if ever, occurs.[termedia.pl] TABLE 4 Conditions That Mimic Cervical Spondylotic Myelopathy on Presentation Amyotrophic lateral sclerosis Extrinsic neoplasia (metastatic tumors) Hereditary spastic paraplegia[aafp.org]

  • Pernicious Anemia

    When the deficiency is severe, symptoms can worsen, leading to severe weakness, spasticity, paraplegia, and fecal and urinary incontinence .[emedicinehealth.com] A severe deficiency can result in more serious neurological symptoms, including severe weakness, spasticity , paraplegia, and fecal and urinary incontinence .[medicinenet.com]

  • Myelitis

    The differential diagnosis in hereditary spastic paraplegia includes: multiple sclerosis cervical spondylosis with cervical myelopathy indolent spinal cord or foramen magnum[gpnotebook.co.uk] Hello, Juliet, Hereditary spastic paraplegia (HSP) is one of the degenerative diseases of the nervous system.[medhelp.org]

  • X-linked Parkinsonism-Spasticity Syndrome

    "Hereditary spastic paraplegia". nhs.uk. 2017-10-18. Retrieved 2018-01-28. Fink JK (2003). "The Hereditary Spastic Paraplegias".[en.wikipedia.org] spastic paraplegia loci.[journals.lww.com] Today I'm going to talk about the genetics of hereditary spastic paraplegia. 0:18 Hereditary spastic paraplegia, or HSP, refers to a clinical designation for neurological[hstalks.com]

  • Cervical Herniated Disc

    For patients with more severe symptoms, such as spastic paresis and paraplegia, or those who fail conservative therapy, surgical treatment may be necessary.[symptoma.com]

  • Myelopathy

    Hereditary spastic paraplegia (also called familial spastic paraplegia or Strumpell-Lorrain disease) is not a single disease, but rather a heterogeneous group of genetic disorders[massagetoday.com] ., metastatic tumors), subacute combined degeneration of the spinal cord (vitamin B 12 deficiency), hereditary spastic paraplegia, normal pressure hydrocephalus and spinal[aafp.org] , the main feature of which is progressive spasticity in the lower limbs due to pyramidal tract dysfunction.[massagetoday.com]

  • Cerebral Palsy

    Related phenotypes that were formerly classified in the CPSQ series include spastic paraplegia-47 (SPG47; 614066), spastic paraplegia-50 (SPG50; 612936), spastic paraplegia[ncbi.nlm.nih.gov] Many children with spastic hemiplegia or paraplegia have normal intelligence; children with spastic quadriplegia or a mixed syndrome may have severe intellectual disability[merckmanuals.com] Familial spastic paraplegia is well recognised and the clinician should always ask about family members with an unusual walking gait since childhood.[web.archive.org]

  • Pelizaeus-Merzbacher Disease

    The disease spectrum for Pelizaeus-Merzbacher disease and spastic paraplegia type 2 is extraordinarily broad, ranging from a spastic gait in the pure form of spastic paraplegia[ncbi.nlm.nih.gov] We report on a C-to-T transition in exon 6 of the PLP gene in a male with Pelizaeus-Merzbacher disease/X-linked spastic paraplegia.[ncbi.nlm.nih.gov] Abstract Pelizaeus-Merzbacher disease (PMD) and its allelic disorder, spastic paraplegia type 2 (SPG2), are among the best-characterized dysmyelinating leukodystrophies of[ncbi.nlm.nih.gov]

  • Spinal Cord Injury

    Recovery of sensory and supraspinal control of leg movement in people with chronic paraplegia: A case series. Arch. Phys. Med. Rehabil. 95(4): 610 – 614 ; 2014.[doi.org] Functional electrical stimulation and suppression of spasticity following spinal cord injury. Bull. N. Y. Acad. Med. 68(2): 351 – 364 ; 1992. Google Scholar Medline 206.[doi.org]

  • Cervical Myelopathy

    Hereditary spastic paraplegia (also called familial spastic paraplegia or Strumpell-Lorrain disease) is not a single disease, but rather a heterogeneous group of genetic disorders[massagetoday.com] paraplegia, normal pressure hydrocephalus, and spinal cord infarction can be easily differentiated on specific MRI findings.[boneandspine.com] , the main feature of which is progressive spasticity in the lower limbs due to pyramidal tract dysfunction.[massagetoday.com]

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