Spastic Paraplegia Causes & Reasons

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Spastic Paraplegia Symptom Checker: Possible causes include Cervical Spondylosis. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.

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Possible Causes

Cervical Spondylosis

metastatic tumors), subacute combined degeneration of the spinal cord (vitamin B 12 deficiency), hereditary spastic paraplegia, normal pressure hydrocephalus and spinal [aafp.org]

Severe cases of cervical spinal canal stenosis can also cause paraplegia, and significant loss of function also rarely, if ever, occurs. [termedia.pl]

TABLE 4 Conditions That Mimic Cervical Spondylotic Myelopathy on Presentation Amyotrophic lateral sclerosis Extrinsic neoplasia (metastatic tumors) Hereditary spastic paraplegia [aafp.org]

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Pernicious Anemia

When the deficiency is severe, symptoms can worsen, leading to severe weakness, spasticity, paraplegia, and fecal and urinary incontinence. [emedicinehealth.com]

A severe deficiency can result in more serious neurological symptoms, including severe weakness, spasticity, paraplegia, and fecal and urinary incontinence. [medicinenet.com]

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X-linked Parkinsonism-Spasticity Syndrome

"Hereditary spastic paraplegia". nhs.uk. 2017-10-18. Retrieved 2018-01-28. Fink JK (2003). "The Hereditary Spastic Paraplegias". [en.wikipedia.org]

spastic paraplegia loci. [journals.lww.com]

[…] hereditary spastic paraplegia 34 (DOID:0110785) Alliance: disease page Synonyms: SPG34; X-linked spastic paraplegia 34; X-linked spastic paraplegia type 34 Alt IDs: OMIM:300750 [informatics.jax.org]

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Myelitis

The differential diagnosis in hereditary spastic paraplegia includes: multiple sclerosis cervical spondylosis with cervical myelopathy indolent spinal cord or foramen magnum [gpnotebook.co.uk]

Hello, Juliet, Hereditary spastic paraplegia (HSP) is one of the degenerative diseases of the nervous system. [medhelp.org]

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Myelopathy

Hereditary spastic paraplegia (also called familial spastic paraplegia or Strumpell-Lorrain disease) is not a single disease, but rather a heterogeneous group of genetic disorders [massagetoday.com]

metastatic tumors), subacute combined degeneration of the spinal cord (vitamin B 12 deficiency), hereditary spastic paraplegia, normal pressure hydrocephalus and spinal [aafp.org]

the main feature of which is progressive spasticity in the lower limbs due to pyramidal tract dysfunction. [massagetoday.com]

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Cervical Herniated Disc

For patients with more severe symptoms, such as spastic paresis and paraplegia, or those who fail conservative therapy, surgical treatment may be necessary. [symptoma.com]

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Cerebral Palsy

Related phenotypes that were formerly classified in the CPSQ series include spastic paraplegia-47 (SPG47; 614066), spastic paraplegia-50 (SPG50; 612936), spastic paraplegia [ncbi.nlm.nih.gov]

Many children with spastic hemiplegia or paraplegia have normal intelligence; children with spastic quadriplegia or a mixed syndrome may have severe intellectual disability [msdmanuals.com]

51 (SPG51; 613744), and spastic paraplegia-52 (614067). [ncbi.nlm.nih.gov]

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Pelizaeus-Merzbacher Disease

The disease spectrum for Pelizaeus-Merzbacher disease and spastic paraplegia type 2 is extraordinarily broad, ranging from a spastic gait in the pure form of spastic paraplegia [ncbi.nlm.nih.gov]

Abstract Pelizaeus-Merzbacher disease (PMD) and its allelic disorder, spastic paraplegia type 2 (SPG2), are among the best-characterized dysmyelinating leukodystrophies of [ncbi.nlm.nih.gov]

We report on a C-to-T transition in exon 6 of the PLP gene in a male with Pelizaeus-Merzbacher disease/X-linked spastic paraplegia. [ncbi.nlm.nih.gov]

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Spinal Cord Injury

Recovery of sensory and supraspinal control of leg movement in people with chronic paraplegia: A case series. Arch. Phys. Med. Rehabil. 95(4): 610 – 614 ; 2014. [doi.org]

Functional electrical stimulation and suppression of spasticity following spinal cord injury. Bull. N. Y. Acad. Med. 68(2): 351 – 364 ; 1992. Google Scholar Medline 206. [doi.org]

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Cervical Myelopathy

paraplegia, normal pressure hydrocephalus, and spinal cord infarction can be easily differentiated on specific MRI findings. [boneandspine.com]

the main feature of which is progressive spasticity in the lower limbs due to pyramidal tract dysfunction. [massagetoday.com]

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Lathyrism

Clinical manifestations are marked by spastic paraplegia, and degenerative pathological changes are noted in the spinal cord to account for this effect. [doi.org]

Progressive spastic paraplegia.. Pain.. Hyperesthesia.. Paresthesia.. Angiolathyrism - causes sudden death.. Aneurisms.. [specialityclinic.com]

Main involvement is spastic paraplegia with exaggerated tendon jerks and extensor response plantar. [healthdrip.com]

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Paraparesis

FURTHER INFORMATION / LINKS Gene Reviews Hereditary Spastic Paraplegia Overview Gene Reviews Spastic Paraplegia Type 4 Gene Reviews Spastic Paraplegia 3A Gene Reviews Spastic [bwc.nhs.uk]

Pure hereditary spastic paraplegia The main symptoms of pure hereditary spastic paraplegia are: a gradual weakness in the legs increased muscle tone and stiffness (spasticity [nhs.uk]

Hereditary Spastic Paraplegia/Paraparesis (HSP) Hereditary Spastic Paraplegia/Paraparesis (HSP) TESTING STRATEGY For autosomal dominant HSP; automated sequence analysis is [bwc.nhs.uk]

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Laurence Moon Syndrome

From Wikidata Jump to navigation Jump to search rare autosomal recessive genetic disorder associated with retinitis pigmentosa, spastic paraplegia, and mental disabilities [wikidata.org]

In the majority of the presently known Laurence-Moon syndrome cases, the disease has a childhood onset, characterized by cerebellar ataxia, spastic paraplegia, peripheral [symptoma.com]

Lau·rence-Moon syn·drome ( law'rĕnts mūn ), [MIM*245800] disorder characterized by mental retardation, pigmentary retinopathy, hypogenitalism, and spastic paraplegia; autosomal [medical-dictionary.thefreedictionary.com]

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Syringomyelia

Syringomyelia is a rare disease of the spinal cord characterized by the presence of a fluid-filled cavity, with resulting neurologic defects. The symptoms of syringomyelia usually present slowly and may eventually lead to permanent disabilities. Signs and symptoms of significant syrinx formation are mostly observed in[…] [symptoma.com]

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Hematomyelia

[…] the spinal cord due to increased venous pressure (usually due to AVF; less commonly AVMs) and often involves acute to sub-acute progression of neurological deficits from spastic [emedicine.medscape.com]

paraplegia to flaccid paralysis, loss of sphincter tone, and ascending sensory loss. [9] Spinal subarachnoid hemorrhage (SAH) may cause symptoms due to blood in the subarachnoid [emedicine.medscape.com]

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Hereditary Spastic Paraplegia

Hereditary spastic paraplegia: advances in genetic research. [ncbi.nlm.nih.gov]

[…] of the lower limbs HSMN V familial spastic paraplegia Strümpell-Lorrain disease French settlement disease Strumpell-Lorrain disease hereditary spastic paraparesis FSP HSP [wikidata.org]

Abstract Purpose of review Hereditary spastic paraplegias are a genetically heterogeneous group of diseases. [doi.org]

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Spinal Cord Compression

Examination revealed functional upper extremities with spastic paraplegia of bilateral lower extremities. [ncbi.nlm.nih.gov]

The cord symptoms were often noted to progress rapidly to a flaccid paraplegia, although a slowly progressive spastic paraplegia could occur. [medlink.com]

paraplegia with a sensory level at the trunk Weakness of the legs, sacral loss of sensation and extensor (upward) plantar reflexes Specific syndromes associated with cord [dundeemedstudentnotes.wordpress.com]

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Infantile-Onset Ascending Hereditary Spastic Paralysis

Spastic paraplegia began during the first 2 years of life and extended to upper limbs within the next few years. [ncbi.nlm.nih.gov]

All were considered normal at birth, and spastic paraplegia started approximately at the age of walking achievement. [ncbi.nlm.nih.gov]

Infantile-onset ascending hereditary spastic paralysis is one of a group of genetic disorders known as hereditary spastic paraplegias. [ghr.nlm.nih.gov]

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Primary Lateral Sclerosis

Primary lateral sclerosis (PLS) and hereditary spastic paraplegia (HSP) are clinically similar disorders in which progressive lower limb spasticity and corticospinal tract [ncbi.nlm.nih.gov]

The most common are Hereditary Spastic Paraplegia (or Paraparesis), Familial Spastic Paraparesis (or Paraplegia), and Strümpell-Lorrain Disease. [bravelets.com]

paraplegias (HSP). [ncbi.nlm.nih.gov]

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Pallidopyramidal Syndrome

@inproceedings{Bulboaca2019PallidopyramidalSA, title {Pallidopyramidal Syndrome and Hereditary Spastic Paraplegia common features and diagnostic approach and therapeutic considerations [semanticscholar.org]

MalaCards based summary : Parkinson Disease 15, Autosomal Recessive Early-Onset, also known as pallidopyramidal syndrome, is related to complex hereditary spastic paraplegia [malacards.org]

Pallidopyramidal syndrome and hereditary spastic paraplegia (HSP) can present common features and diagnostic approach has to be careful. genetic assessment is the gold diagnosis [semanticscholar.org]

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Juvenile Primary Lateral Sclerosis

Disease Type of connection Autosomal recessive spastic paraplegia type 18 Infantile-onset ascending hereditary spastic paralysis Juvenile amyotrophic lateral sclerosis Recessive [csbg.cnb.csic.es]

@article{GrosLouis2003AnAG, title {An ALS2 gene mutation causes hereditary spastic paraplegia in a Pakistani kindred.}, author {François Gros-Louis and Inge A. [semanticscholar.org]

ALS amyotrophic lateral sclerosis ; AR autosomal recessive ; bp base pair ; CMAP compound muscle action potential amplitudes ; IAHSP infantile-onset ascending hereditary spastic [neurology.org]

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Cervical Spinal Cord Tumor

Charles Posted Tue 02nd of October, 2012 20:22:31 PM I need help coding the following Surgical Precert: ***No op report*** 1. Cervical Laminotomy C6-T1 with resection of spinal cord tumor/mass (Surgeon will be putting the bone back in with plate and screws) Thinking the following: Laminotomy - 63020 for C6, and[…] [supercoder.com]

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Diffuse Cerebral Sclerosis of Schilder

[…] paraparesis Systemic atrophies primarily affecting the CNS Huntington's Spinocerebellar ataxia ( Friedreich's ataxia, Ataxia telangiectasia, Hereditary spastic paraplegia [wikidoc.org]

paraplegia ) Spinal muscular atrophy : Werdnig-Hoffman disease - Kugelberg-Welander disease - Fazio Londe syndrome - MND ( Amyotrophic lateral sclerosis (ALS), Progressive [bionity.com]

paraplegia, followed by mental and physical deterioration. [icd9data.com]

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Distal Spinal Muscular Atrophy Type 5

paraplegia, neurolathyrism, Konzo). [link.springer.com]

intellectual disability - dysmorphism Aminolevulinate dehydratase deficiency porphyria Ankyloblepharon filiforme imperforate anus Spastic paraplegia 7 Spastic paraplegia [checkrare.com]

See also [ edit ] Motor neuron disease Hereditary motor and sensory neuropathies Spinal muscular atrophies Charcot–Marie–Tooth disease Hereditary spastic paraplegia References [en.wikipedia.org]

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Upper Motor Neuron Disease

Please help us raise some money for the Spastic Paraplegia Foundation (SPF) to support HSP research. [gofundme.com]

Patients with hereditary spastic paraplegia or meeting revised El Escorial electrodiagnostic criteria for amyotrophic lateral sclerosis were excluded. [ncbi.nlm.nih.gov]

Hereditary Spastic Paraplegia (HSP) is a group of rare inherited neurological disorders that are progressive and cause patients to be unable to walk, and more. [gofundme.com]

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Sjögren-Larsson Syndrome

The Sjogren-Larsson syndrome is a neurocutaneous, autosomal recessive and disabling condition, characterized by congenital ichthyosis, spastic paraplegia and mental retardation [ncbi.nlm.nih.gov]

Both the patients had generalized ichthyosis, and the older one had spastic paraplegia and mental retardation, and the fundus examination revealed foveal and parafoveal glistening [ncbi.nlm.nih.gov]

paraplegia. [medical-dictionary.thefreedictionary.com]

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Globoid Cell Leukodystrophy

paraplegia from the middle of the second decade, and all patients had diminished GALC activity in their leukocytes. [ncbi.nlm.nih.gov]

paraplegia, followed by mental and physical deterioration. [icd10data.com]

[…] polymorphism (PCR-SSCP) analysis, subsequent sequence determination, and restriction enzyme digestion of PCR products, initial symptoms were the onset of slowly progressive spastic [ncbi.nlm.nih.gov]

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Pyramidal Tract Lesion

Hereditary spastic paraparesis HSP, also known as familial spastic paraplegias or Strumpell-Lorrain disease, comprises a clinically and genetically heterogeneous group of [emedicine.medscape.com]

But I just read in this website spastic cerbral palsy is pyramidal and non spastic is extrapyramidal. How can that be? [physicsforums.com]

Of the 45 known gene loci, 20 have been identified as causative. [57] About 40% of autosomal dominant HSP cases are linked to the spastic paraplegia 4 (SPG4) locus on chromosome [emedicine.medscape.com]

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Distal Spinal Muscular Atrophy Type 4

Hereditary spastic paraplegia (HSP). See Hereditary Spastic Paraplegia Overview. [cmm.ucsd.edu]

Hereditary spastic paraplegia (HSP) : Although dominant autosomal trait is the most common one, recessive and X-linked inheritance exist. [neuroweb.us]

By contrast, pseudobulbar palsy, primary lateral sclerosis (PLS), and familial spastic paraplegia (FSP) affect only upper motor neurons innervating the brainstem and spinal [accessmedicine.mhmedical.com]

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Spinal Cord Transection

: Strumpell's familial spastic paraplegia: genetics and neuropathology. J. Neurol. Neurosurg. Psychiatry 37:8–20, 1974. [link.springer.com]

Posted on April 12, 2016 by admin Evaluation of the effects of muscle stretch and weight load in patients with spastic paraplegia. date: 01/01/1981 author: Odeen I, Knutsson [easystand.com]

CrossRef PubMed Google Scholar [10] Harding A.E. : Hereditary “pure” spastic paraplegia: a clinical and genetic study of 22 families. J. Neurol. Neurosurg. [link.springer.com]

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