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381 Possible Causes for Splenomegaly, Typhoid Fever

  • Infectious Mononucleosis

    Fever of unknown origin (FUO) in an elderly adult due to Epstein-Barr virus (EBV) presenting as "typhoidal mononucleosis," mimicking a lymphoma.[emedicine.medscape.com] Clinical estimates of splenomegaly are fallible.[ncbi.nlm.nih.gov] In adolescent and adult patients presenting with sore throat, the presence of posterior cervical, inguinal or axillary adenopathy, palatine petechiae, splenomegaly, or atypical[ncbi.nlm.nih.gov]

  • Gastrointestinal Hemorrhage

    This is often due to pre-existing liver disease and splenomegaly.[geekymedics.com] Other signs to look for are ascites and erythema (chronic liver disease) and splenomegaly and dilated abdominal wall veins (portal hypertension).[uspharmacist.com] […] bleeding disorders (eg, petechiae, ecchymoses) are sought, as are signs of chronic liver disease (eg, spider angiomas, ascites, palmar erythema) and portal hypertension (eg, splenomegaly[merckmanuals.com]

  • Subacute Bacterial Endocarditis

    (083.0) typhoid (fever) (002.0) Excludes: endocarditis (in): Coxsackie (virus) (074.22) gonococcal (098.84) histoplasmosis (115.0-115.9 with fifth-digit 4) meningococcal[icd9.chrisendres.com] Fever, anaemia, splenomegaly and positive blood cultures for Gram-negative bacteria were found on admission.[ncbi.nlm.nih.gov] Findings compatible with both SBE and marantic endocarditis due to a B-cell lymphoproliferative disorder included an elevated ESR, and splenomegaly.[ncbi.nlm.nih.gov]

  • Salmonella Infection

    Salmonella infection causes common gastroenteritis as well as typhoid fever, which is a serious, sometimes fatal, disease.[symptoma.com] Typhoid fever, a more serious disease caused by Salmonella, is not common in the United States. It frequently occurs in developing countries.[web.archive.org] Salmonella enterica subspecies enterica includes several serovars infecting both humans and other animals and leading to typhoid fever or gastroenteritis.[ncbi.nlm.nih.gov]

  • Viral Hepatitis

    Abstract A typhoid patient presenting with fever and jaundice is reported. Investigations revealed that the patient had both typhoid fever and acute viral hepatitis A.[ncbi.nlm.nih.gov] We are reporting an unusual combination of Typhoid fever and viral hepatitis in a G6PD deficient individual.[ncbi.nlm.nih.gov] Jaundice is a rare clinical presentation in typhoid fever, therefore hepatitis A should be considered in typhoid fever and jaundice because both enterically transmitted disease[ncbi.nlm.nih.gov]

  • Adult-Onset Still Disease

    […] clinically by high spiking fever, polyarthralgia/arthritis, a salmon-pink evanescent rash, predominantly neutrophilic leucocytosis, lymphadenopathy, liver dysfunction, and splenomegaly[ncbi.nlm.nih.gov] Arthritis (OR, 8.6; 95% confidence interval [CI], 1.5-49.1; p 0.014), pharyngitis (OR, 6.9; 95% CI, 1.5-30.2; p 0.010), splenomegaly (OR, 5.4; 95% CI, 1.1-26.7; p 0.039),[ncbi.nlm.nih.gov] AOSD patients with RHS showed significantly higher frequencies of splenomegaly, hepatomegaly, and lymphadenopathy than did those without RHS.[ncbi.nlm.nih.gov]

  • Plasmodium Falciparum Malaria

    January 11, 2019 Weekly Digest: XDR typhoid fever in Pakistan; Flu activity rising in northern hemisphere and south Asia; Antibiotic use on Pennsylvania dairy farms.[cddep.org] Two black African immigrants, with no history of recent travel outside France, received a diagnosis of a malignant lymphoproliferative disorder and splenomegaly, and they[ncbi.nlm.nih.gov] fever and malaria. 3,4 There is much overlap between presentations of both P. falciparum malaria and Ebola virus disease.[journals.lww.com]

  • Malaria

    fever, viral hepatitis, encephalitis.[ncbi.nlm.nih.gov] Abstract We report the case of a 12-year-old child who was admitted to our Department, with 7 days' history of high fever and splenomegaly.[ncbi.nlm.nih.gov] […] to no nets and in areas of stable malaria, ITNs also had an impact on severe malaria (45% PE, 95% CI 20 to 63), parasite prevalence (13% PE), high parasitaemia (29% PE), splenomegaly[ncbi.nlm.nih.gov]

  • Brucellosis

    Statistics showed an impressive reduction of enteric fever. Typhoid inoculation was then used extensively in the British Army during the Great War.[whonamedit.com] She subsequently developed a fever and was diagnosed with pancytopenia and moderate splenomegaly.[ncbi.nlm.nih.gov] The most frequent admission symptoms and findings of the patients with pancytopenia were fever (75%), fatigue (50%), splenomegaly (75%), and hepatomegaly (41%).[ncbi.nlm.nih.gov]

  • Q Fever

    Of patients assessed, 8.9%, 22.4%, 1.1%, and 3.6% had enhanced seroreactivity to Coxiella burnetii, spotted fever group rickettsiae, typhus group rickettsiae, and scrub typhus[ncbi.nlm.nih.gov] This case describes a man who, after extensive investigation for splenomegaly and pancytopenia by several specialties, was finally diagnosed with Q fever endocarditis after[ncbi.nlm.nih.gov] Seroprevalence was highest against scrub typhus group (STG) (22.6%) followed by spotted fever group (SFG) rickettsia (15.7%), Q fever (QF) (6.9%) and typhus group (TG) rickettsia[ncbi.nlm.nih.gov]

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