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1,638 Possible Causes for Splenomegaly, Vasculitis

  • Infectious Mononucleosis

    Clinical estimates of splenomegaly are fallible.[ncbi.nlm.nih.gov] EBV infection , including: Infantile papular acrodermatitis (Gianotti-Crosti syndrome ) Erythema multiforme Erythema nodosum Urticaria including cold urticaria Urticarial vasculitis[dermnetnz.org] Not only morbilliform lesions, but in some cases urticarial, purpuric and vesicular rashes, pustular eyrthematous rash, universal erythema or cutaneous vasculitis in the erythema[omicsonline.org]

  • Rheumatoid Arthritis

    It is extremely rare for RA to present as FS or develop after initially presenting as neutropaenia and splenomegaly.[ncbi.nlm.nih.gov] Extensive investigations did not reveal evidences of other systemic causes such as malignancy or systemic vasculitis.[ncbi.nlm.nih.gov] […] anti-citruillated plasma antibody (ACPA): it is more than 80% sensitive and more than 95% specific elevated ESR or C-reactive protein Associations Felty syndrome : rheumatoid arthritis, splenomegaly[radiopaedia.org]

  • Felty's Syndrome

    Computed tomography of the pelvis led to an incorrect diagnosis of malignancy, while radionuclide imaging using Tc-99m sulfur colloid confirmed the diagnosis of ectopic splenomegaly[ncbi.nlm.nih.gov] We address the issue of "adding fuel to the fire" and review reported implications of GCSF in induction of vasculitis.[ncbi.nlm.nih.gov] Abstract The syndrome of atrophic polyarthritis occurring in an adult, associated with fever, secondary anemia, leukopenia and splenomegaly, was described by Felty 1 in 1924[annals.org]

  • Gastrointestinal Hemorrhage

    This is often due to pre-existing liver disease and splenomegaly.[geekymedics.com] We describe a case of systemic Candida albicans infection associated with life-threatening gastrointestinal hemorrhage due to unusual necrotizing vasculitis involving the[ncbi.nlm.nih.gov] Other signs to look for are ascites and erythema (chronic liver disease) and splenomegaly and dilated abdominal wall veins (portal hypertension).[uspharmacist.com]

  • Familial Mediterranean Fever

    Her persistent left elbow effusion resolved and her splenomegaly rapidly disappeared.[bloodjournal.org] An association of FMF with systemic vasculitis, namely Henoch-Schönlein purpura, polyarteritis nodosa and Behçet's disease has been described.[ncbi.nlm.nih.gov] Cutaneous necrotizing vasculitis repeatedly emerging with febrile attacks should be included among the skin manifestations of FMF.[ncbi.nlm.nih.gov]

  • Gaucher Disease

    HALS for GD patients with refractory hypersplenism and massive splenomegaly is safe and feasible in experienced hands.[ncbi.nlm.nih.gov] Cutaneous leukocytoclastic vasculitis (CLV) is a necrotizing inflammation of the small vessels in the dermis.[ncbi.nlm.nih.gov] After 4years of ERT, therapeutic goals for thrombocytopenia and splenomegaly had been achieved in 100% of patients; goals for anemia and hepatomegaly had been achieved in[ncbi.nlm.nih.gov]

  • Brucellosis

    The most frequent admission symptoms and findings of the patients with pancytopenia were fever (75%), fatigue (50%), splenomegaly (75%), and hepatomegaly (41%).[ncbi.nlm.nih.gov] […] arthralgia and rash on legs, diagnosed with brucellosis through brucellosis tube agglutination test and found to have splenic infarct upon examination and leukocytoclastic vasculitis[ncbi.nlm.nih.gov] Tender hepatomegaly or splenomegaly was striking in seven patients. Other characteristics included epistaxis, arthralgia, myalgia, and weight loss.[pediatrics.aappublications.org]

  • Tsutsugamushi Disease

    As the disease progresses, pneumonia, encephalitis, delirium and splenomegaly may be added to the clinical picture.[symptoma.com] Leukocytoclastic vasculitis and basal vacuolar changes were the characteristic features of the eschar and the erythematous lesions, respectively.[ncbi.nlm.nih.gov] […] there is a sudden onset of headache, malaise, anorexia, weakness, and fever, followed by pneumonia, a macular rash (on the trunk before the limbs), lymphadenopathy, hepato-splenomegaly[histopathology-india.net]

  • Disseminated Histoplasmosis

    This case highlights consideration of disseminated histoplasmosis in patients presenting with diffuse adenopathy along with hepatomegaly and/or splenomegaly in the right clinical[ncbi.nlm.nih.gov] Differential diagnoses such as malignant tumors, cocaine use, granulomatosis, vasculitis and infections are more frequently observed and could delay and/or bias the final[ncbi.nlm.nih.gov] On the basis of a comparative analysis of those who died and survived, the absence of splenomegaly and hepatomegaly and the presence of H. capsulatum in the peripheral blood[ncbi.nlm.nih.gov]

  • Typhus

    The most common CT finding was hepatomegaly (74.4%), followed by splenomegaly (66.7%).[ncbi.nlm.nih.gov] An autopsy revealed systemic vasculitis and perivasculitis. The endothelial tissue of the white pulp of the spleen was markedly infiltrated by plasma cells.[ncbi.nlm.nih.gov] The disease manifestations are thought to result from a systemic vasculitis, caused by both direct effects of the organisms as well as an exaggerated immune response, although[ncbi.nlm.nih.gov]

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