Spontaneous Recurrent Epistaxis: Causes & Reasons

Possible Causes for Spontaneous Recurrent Epistaxis

Patients with suspicion of HHT based on clinical data, such as: 1) spontaneous recurrent epistaxis, 2) cutaneous telangiectasia, 3) visceral lesions (arteriovenous malformations [admerahealth.com]

Its diagnosis is based on the Curaçao criteria, and is considered definite if at least 3 of the 4 following criteria are fulfilled: (1) spontaneous and recurrent epistaxis [ncbi.nlm.nih.gov]

The Curaçao criteria include the following: Spontaneous recurrent epistaxis Multiple telangiectasias in typical locations Documented visceral arteriovenous malformations [msdmanuals.com]

Hereditary Hemorrhagic Telangiectasia Type 2

recurrent epistaxis Recurring nosebleed Spontaneous, recurrent nosebleed [ more ] 0004406 Tongue telangiectasia 0000227 Showing of 58 | Last updated: 12/1/2018 Making a [rarediseases.info.nih.gov]

Individuals with HHT are at risk for spontaneous and recurrent nosebleeds (epistaxis) and hemorrhages in the brain, liver, lungs, or other organs. [invitae.com]

Hemophilia B

recurrent epistaxis Recurring nosebleed Spontaneous, recurrent nosebleed [ more ] 0004406 Percent of people who have these symptoms is not available through HPO Abnormal [rarediseases.info.nih.gov]

[…] surgery Protracted bleeding after surgery [ more ] 0004846 Prolonged bleeding time 0003010 Prolonged partial thromboplastin time 0003645 Reduced factor IX activity 0011858 Spontaneous [rarediseases.info.nih.gov]

Hemophilia A

Hemophilia A: Classic hemophilia, which is due to a profound deficiency in the activity of clotting factor VIII. Affected individuals suffer hemorrhage into joints and muscles, easy bruising, and prolonged bleeding from wounds. The disease is inherited as an X-linked trait, so males are affected and females carry the[…] [medicinenet.com]

Mucocutaneous Venous Malformations

Epidemiologic studies suggest the prevalence is one in 5,000 to 8,000 persons in most populations. 1 Spontaneous, recurrent epistaxis from telangiectasia of the nasal mucosa [aafp.org]

The Curacao criteria helps in arriving at a definite diagnosis of HHT if at least three of the following clinical manifestations are present Spontaneous recurrent epistaxis [medcraveonline.com]

Our patient had spontaneous and recurrent epistaxis along with recurrent gum bleeding, with the background of a family history of epistaxis and gum bleeding. [lungindia.com]

Severe Hemophilia A

OBJECTIVES: This article presents a cost-utility analysis from the Colombian health system perspective comparing primary prophylaxis to on-demand treatment using exogenous clotting factor VIII (FVIII) for patients with severe hemophilia type A. METHODS: We developed a Markov model to estimate expected costs and[…] [ncbi.nlm.nih.gov]

Hepatic Arteriovenous Malformation

Two years later, at the age of 16 years she developed spontaneous recurrent epistaxis. She was also noted to have jaundice. [bmcresnotes.biomedcentral.com]

Hereditary hemorrhagic telangectasia (HHT) Symptoms of HHT include: Recurrent spontaneous epistaxis – This is the most common symptom of HHT. [clinicaladvisor.com]

Diagnostic Criteria for HHT (Curaçao Criteria) Criteria Characteristics Epistaxis Spontaneous, recurrent nosebleeds Family history A first-degree relative with HHT Telangiectasias [aafp.org]

Autosomal Recessive Hypohidrotic Ectodermal Dysplasia Type 10B

recurrent epistaxis An important gene associated with Ectodermal Dysplasia 11b, Hypohidrotic/hair/tooth Type, Autosomal Recessive is EDARADD (EDAR Associated Death Domain [malacards.org]

[…] anhidrotic, with immunodeficiency, osteopetrosis, and lymphedema and ectodermal dysplasia, hypohidrotic, with hypothyroidism and ciliary dyskinesia, and has symptoms including spontaneous [malacards.org]

Hereditary Benign Telangiectasia

Spontaneous and recurrent Epistaxis is the most common feature present (> 90 %). [lecturio.com]

Hereditary hemorrhagic telangectasia (HHT) Symptoms of HHT include: Recurrent spontaneous epistaxis – This is the most common symptom of HHT. [clinicaladvisor.com]

recurrent epistaxis Multiple telangiectasias in typical locations (see above) Proven visceral AVM (lung, liver, brain, spine) First-degree family member with HHT Despite [en.wikipedia.org]

Perineural Angioma

[…] and recurrent epistaxis • Mucocutaneous telangiectases, particularly involving the lips, tongue, oral cavity, fingers, and nose • Internal arteriovenous malformations, including [basicmedicalkey.com]

[…] malformations involving skin, mucosal surfaces, and visceral organs • Essential diagnostic criteria comprise (three or more = definite, two = possible, less than two = unlikely) • Spontaneous [basicmedicalkey.com]

Jejunal Vascular Anomaly with Hemorrhage

The estimated frequency of manifestations in patients with HHT is as follows: Spontaneous, recurrent epistaxis - 90% Skin telangiectases - 75% Hepatic or pulmonary involvement [gastrointestinalatlas.com]

Recurrent Thrombophlebitis due to Hereditary Disorders

The Curaçao Criteria for the diagnosis of HHT include: (1) spontaneous, recurrent epistaxis, (2) telangiectasias at the nose, lips, oral cavity, and fingertips, (3) visceral [omicsonline.org]

Angiofibroma

A 50yr old female patient came with complaints of right sided nasal obstruction and recurrent spontaneous epistaxis since 6 months. [webmedcentral.com]

spontaneous epistaxis and nasal drainage is diagnostic of nasopharyngeal angiofibroma. [cancerjournal.net]

A differential diagnosis of angiofibroma should be considered for any patient coming with complaints of nasal mass and spontaneous, recurrent epistaxis irrespective of age [webmedcentral.com]

Peliosis Hepatis

Epistaxis Spontaneous recurrent nosebleeds 2. Mucocutaneous telangiectasia Multiple at characteristic sites: fingertip pulps, lips, oral cavity 3. [gastro.oxfordjournals.org]

Giacheti Syndrome

recurrent epistaxis Hypodontia Wide nasal bridge Depressed nasal bridge Median cleft lip Depressed nasal tip Median cleft lip and palate Semilobar holoprosencephaly Absent [mendelian.co]

Polysplenia Enlarged naris Abnormality of the dentition Clinodactyly of the 5th finger Polydactyly Protruding ear Anal atresia Nail dystrophy Bone marrow hypercellularity Spontaneous [mendelian.co]

Arterial Tortuosity Syndrome

Epistaxis This is one of the symptoms in the classic triad of presentation of HHT. Spontaneous and recurrent episodes of epistaxis is a common presentation. [medicaljoyworks.com]

Angiomyolipoma

Case 1 A 60-year-old male presented with spontaneous, recurrent epistaxis, and left-sided nasal obstruction for 5 months. [ijpmonline.org]

CASE PRESENTATION One male, 54 year-old patient came to our ENT service in 2006, complaining of 20 years of spontaneous and recurrent epistaxis, always on the left side. [scielo.br]

Hepatopathy

She presented with recurrent spontaneous epistaxis, pulmonary arterio venous malformation and oral telangiectasia. [ncbi.nlm.nih.gov]

White Sponge Nevus

Diagnosis The diagnosis is based on the presence of three of the following four findings: spontaneous recurrent epistaxis, mucocutaneous telangiectasia, visceral involvement [pocketdentistry.com]

Deviated Nasal Septum

He denied anosmia, recurrent epistaxis, nasal pain or sensitivity, otalgia, vision problems, or fevers. The patient had no surgical history. [medscape.com]

Frequent spontaneous epistaxis may be a feature in childhood and adolescence, probably due to vascular wall fragility. [doi.org]

He thought that the nasal obstruction would recover spontaneously, but the symptom has persisted. [medscape.com]

Myotonic Syndrome

After Expert Rev Mol rhinophyma early signs [ 13 ] cases of spontaneous recurrent epistaxis [ 90 ] the players... [lorientalspa.ma]

Electrocautery or argon beam ablation is described as a possible treatment option for cases of spontaneous recurrent epistaxis [90]. treatment of rhinophyma and sebaceous [lorientalspa.ma]

Chilblain Lupus Erythematosus Type 1

After Expert Rev Mol rhinophyma early signs [ 13 ] cases of spontaneous recurrent epistaxis [ 90 ] the players... [lorientalspa.ma]

Electrocautery or argon beam ablation is described as a possible treatment option for cases of spontaneous recurrent epistaxis [90]. treatment of rhinophyma and sebaceous [lorientalspa.ma]

Brain Abscess

HHT was first described as a familial disease characterized by episodes of spontaneous and recurrent epistaxis, cutaneous and mucosal visible dilated blood vessels (telangiectasias [jcm.asm.org]

Hereditary Factor I Deficiency

Recurrent spontaneous abortions may occur in women affected with afibrinogenemia. [orpha.net]

(bleeding in joint space) Gastrointestinal bleeding Menorrhagia Traumatic and surgical bleeding Intracranial hemorrhage in rare cases Recurrent spontaneous abortions may [centogene.com]

Clinical description Common manifestations of afibrinogenemia include umbilical cord bleeding, epistaxis, hemarthrosis, gastrointestinal bleeding, menorrhagia, traumatic and [orpha.net]

Hereditary Factor XIIIA Deficiency

hematuria, surgical site bleeding, menorrhagia, joint bleeding, delayed healing, spontaneous abortion, recurrent miscarriage Plasma half life is 9 - 12 days Factor XIII [pathologyoutlines.com]

[…] on factor levels Umbilical cord stump bleeding, intracranial hemorrhage, soft tissue hematoma, bleeding after circumcision, gastrointestinal bleeding, gingival bleeding, epistaxis [pathologyoutlines.com]

Rosacea

Electrocautery or argon beam ablation is described as a possible treatment option for cases of spontaneous recurrent epistaxis [ 90 ]. [doi.org]

Acquired Factor XIII Deficiency

hematuria, surgical site bleeding, menorrhagia, joint bleeding, delayed healing, spontaneous abortion, recurrent miscarriage Plasma half life is 9 - 12 days Factor XIII [pathologyoutlines.com]

Glanzmann Thrombasthenia

B.D., a 34 year old male patient presented with the history of recurrent epistaxis, easy post-traumatic bruising and spontaneous purpuric spots from early childhood. [jpgmonline.com]

[…] hemorrhages such as epistaxis and recurrent, difficult to manage gingival hemorrhages, which are potentially fatal and more than 75% of cases require blood or platelet transfusion [investigacion.upb.edu.co]

Bleeding usually begins early in childhood and follows a characteristic pattern of recurrent, spontaneous episodes of mucosal and cutaneous hemorrhage, epistaxis, frequent [jisppd.com]

Hereditary Koilonychia

Epistaxis that is spontaneous and recurrent Multiple mucocutaneous telangiectasia at characteristic sites such as the lips, nose, tongue and mucous membranes, fingers, conjunctiva [medicaleducationleeds.com]

Autosomal Dominant Aplasia and Myelodysplasia

Clumsiness Infantile onset Peripheral neuropathy Spasticity Motor delay Nephrotic syndrome Spontaneous abortion Tinnitus Monocytopenia Epistaxis Pruritus Arthralgia Abdominal [mendelian.co]

[…] pain Severe viral infection Abnormal natural killer cell morphology Recurrent mycobacterium avium complex infections Severe viral infections Recurrent otitis media Chronic [mendelian.co]

[…] infections Pneumonia Tonsillitis Agranulocytosis Monocytosis Congenital neutropenia Eosinophilia Decreased antibody level in blood Recurrent bacterial infections Meningitis [mendelian.co]