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11 Possible Causes for Steroid Myopathy, Supraclavicular Fat Pads

  • Cushing's Disease

    Steroid induced proximal myopathy leads to lethargy and poor mobility of patients.[symptoma.com] Weight gain in face ( moon face ) Weight gain above the collar bone (supraclavicular fat pad) Weight gain on the back of neck ( buffalo hump ) Skin changes with easy bruising[aans.org] Individuals with Cushing syndrome can develop moon facies, facial plethora, supraclavicular fat pads, buffalo hump, truncal obesity, and purple striae, as shown in the image[emedicine.medscape.com]

  • Cortisone

    myopathy, loss of muscle mass, osteoporosis , vertebral compression fractures, aseptic necrosis of femoral and humoral heads, pathologic fracture of long bones, and tendon[drugs.com] Cushing's syndrome invariably presents with a classical phenotype comprising central adiposity, prominence of dorsal, supraclavicular and temporal fat pads, bruising, abdominal[ncbi.nlm.nih.gov] […] abdominal distention, nausea , increased appetite, and ulcerative esophagitis have been reported. [ Ref ] Musculoskeletal Musculoskeletal side effects including muscle weakness, steroid[drugs.com]

  • Adrenal Cortex Hormone

    The main concerns are infections , hypertension , diabetes, osteoporosis, avascular necrosis , myopathy, cataracts , and glaucoma . The list that follows is incomplete.[dermnetnz.org] Cutaneous adverse effects Cutaneous adverse effects from long-term systemic steroids may include: Bacterial infections : cellulitis , wound infection Fungal infections : tinea[dermnetnz.org] […] but infant should be monitored for adrenal suppression if mother on 40 mg prednisone daily Musculoskeletal system Bone fracture Osteoporosis Osteonecrosis, especially hip Myopathy[dermnetnz.org]

  • Cushing Syndrome

    Protein catabolism (glucocorticoid excess) Muscle wasting, weakness (steroid myopathy); thinned skin, capillary fragility.[cushings-help.com] Features more specific to Cushing's syndrome include proximal muscle weakness, supraclavicular fat pads, facial plethora, violaceous striae, easy bruising, and premature osteoporosis[bestpractice.bmj.com] fat pad, sometimes known as a 'buffalo hump' purple skin striae easy skin bruising acanthosis nigricans proximal myopathy depression and other mood disorders osteoporosis[radiopaedia.org]

  • ACTH-Secreting Pituitary Adenoma

    Protein catabolism (glucocorticoid excess) Muscle wasting, weakness (steroid myopathy); thinned skin, capillary fragility.[cushings-help.com] fat pad, sometimes known as a 'buffalo hump' purple skin striae easy skin bruising acanthosis nigricans proximal myopathy depression and other mood disorders osteoporosis[radiopaedia.org] Weight gain (with centripetal distribution, buffalo-hump, supraclavicular fat pad), arterial hypertension, ecchymoses and purple striae on flanks and lower abdomen are all[primarycare.imedpub.com]

  • Cushing Syndrome due to Macronodular Adrenal Hyperplasia

    Protein catabolism (glucocorticoid excess) Muscle wasting, weakness (steroid myopathy); thinned skin, capillary fragility.[cushings-help.com] fat pad, sometimes known as a 'buffalo hump' purple skin striae easy skin bruising acanthosis nigricans proximal myopathy depression and other mood disorders osteoporosis[radiopaedia.org] Presentation Truncal obesity, supraclavicular fat pads, buffalo hump, weight gain. Facial fullness, moon facies, facial plethora. Proximal muscle wasting and weakness.[patient.info]

  • Iatrogenic Cushing's Disease

    Cushing's disease Pseudo-Cushing syndrome due to alcohol Steroid induced cushing syndrome 255.0 Excludes congenital adrenal hyperplasia ( 255.2 ) Applies To Adrenal hyperplasia[icd9data.com] Weight gain in face ( moon face ) Weight gain above the collar bone (supraclavicular fat pad) Weight gain on the back of neck ( buffalo hump ) Skin changes with easy bruising[aans.org] Common: centripetal obesity with dorsocervical and supraclavicular fat pads, facial plethora and "moon face," fatigue, hyperglycemia, hypertension, mood lability, easy bruisability[hopkinsguides.com]

  • Nelson Syndrome

    Cushing's disease Pseudo-Cushing syndrome due to alcohol Steroid induced cushing syndrome 255.0 Excludes congenital adrenal hyperplasia ( 255.2 ) Applies To Adrenal hyperplasia[icd9data.com] fat pad, sometimes known as a 'buffalo hump' purple skin striae easy skin bruising acanthosis nigricans proximal myopathy depression and other mood disorders osteoporosis[radiopaedia.org] Individuals with Cushing syndrome can develop moon facies, facial plethora, supraclavicular fat pads, buffalo hump, truncal obesity, and purple striae, as shown in the image[emedicine.medscape.com]

  • Adrenal Cushing Syndrome

    Cushing's disease Pseudo-Cushing syndrome due to alcohol Steroid induced cushing syndrome 255.0 Excludes congenital adrenal hyperplasia ( 255.2 ) Applies To Adrenal hyperplasia[icd9data.com] fat pad, sometimes known as a 'buffalo hump' purple skin striae easy skin bruising acanthosis nigricans proximal myopathy depression and other mood disorders osteoporosis[radiopaedia.org] She showed no sign of easy bruising, thinning of the skin, supraclavicular fat pads, a buffalo hump or purple striae.[edmcasereports.com]

  • Myopathy, Endocrine

    Presentations range anywhere from acute, painful, and necrotic myopathies, as can occur in statin myopathy, to more insidious presentations such as steroid myopathy.[ncbi.nlm.nih.gov] Abdominal striae, truncal obesity, moon facies, supraclavicular fat pads, and a buffalo hump suggest steroid excess, either exogenous or related to Cushing's syndrome.[clinicalpainadvisor.com] Steroid myopathy and the myopathy associated with excess ACTH have a typical pattern of proximal weakness affecting the legs more than the arms.[ncbi.nlm.nih.gov]

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