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809 Possible Causes for stop, TPA

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  • Tenecteplase

    Decision rules comparing this dose to rt-PA would cause stopping for futility at phase II end, or continuation to phase III.[ncbi.nlm.nih.gov] Functional outcomes were very similar to those of 13 patients with early IV-tPA recanalization.[ncbi.nlm.nih.gov] Decision rules were devised to yield a clear recommendation to either stop for futility or to continue into Phase III.[ncbi.nlm.nih.gov]

  • Alteplase

    In this case report, we describe a 48-year-old male patient with a history of mechanical aortic valve replacement surgery, who stopped taking prescribed warfarin therapy 2[ncbi.nlm.nih.gov] OBJECTIVE: To review and evaluate the evidence regarding the use of low-dose regimens of alteplase (tPA) for the treatment of pulmonary embolism (PE).[ncbi.nlm.nih.gov] The alteplase infusion was stopped, and following antiallergic therapy, tachycardia and hypotension resolved within 1 hour.[ncbi.nlm.nih.gov]

  • Meningitis

    Meningitis epidemics occur annually during the dry season (January to May) and stop with the first rains.[ncbi.nlm.nih.gov] At 4 h, 6 min after onset, intravenous administration of rt-PA (alteplase, 0.6 mg/kg) was started. Her neurological deficits improved rapidly, and her NIHSS score was 1.[ncbi.nlm.nih.gov] This study was stopped early due to excess adverse effects.[ncbi.nlm.nih.gov]

  • Reteplase

    BACKGROUND: Acute lower gastrointestinal hemorrhage (LGIB) usually stops spontaneously.[ncbi.nlm.nih.gov] Because they work on the clotting system, tPAs (such as alteplase , reteplase , and tenecteplase ) are used clinically to treat embolic or thrombotic strokes.[osmosis.org] The safety stopping rule was not activated in any of the tiers. One symptomatic intracerebral hemorrhage was observed in one of the 20 patients (in the 1-unit tier).[ncbi.nlm.nih.gov]

  • Thrombolytic Therapy

    When bleeding from the access site stops and your vital signs are normal, you may be discharged.[dignityhealth.org] It differs from alteplase by 6 amino acids Indications Acute myocardial infarction- streptokinase, tPA (Alteplase, Reteplase & Tenecteplase) Acute ischemic stroke - tPA (Alteplase[careinternet.net] You may be asked to stop medications that increase the risk of bleeding and other complications.[vr.net.au]

  • Anistreplase

    Check with your health care professional before stopping or starting any of your medicines. What should I watch for while taking anistreplase?[bartonhealth.org] (tPA, ongoing) (TEAM-III).[ncbi.nlm.nih.gov] Drug Category Thrombolytic Agents Dosage Forms Powder for solution Brands / Synonyms Alteplase; Eminase (Wulfing Pharma GmbH) ; Reteplase; t- PA; t-plasminogen activator;[druglib.com]

  • Lanoteplase

    Thrombolytics can stop a heart attack that would otherwise be larger or potentially deadly.[sutterhealth.org] (Lanoteplase/SUN9216)and Recombinant tPA(Alteplase)for Acute Myocardial Infarction 著者 Ogata Nobuhiko 著者 Ogawa Hisao 著者 Ogata Yasuhiro 著者 Numata Yuichi 著者 Morigami Yasuhiro[iss.ndl.go.jp] Thrombolytic therapy with mutant tPA or rtPA was carried out consecutively in 21 patients with AMI (8 patients as the mutant tPA group, and 13 patients as the rtPA group).[jstage.jst.go.jp]

  • Fibrinolysis

    Treatment with rt-PA was stopped, and the patient needed a permanent shunt.[ncbi.nlm.nih.gov] Both aptamers bind tPA with low nanomolar affinity and inhibit tPA-mediated activities in a way that is consistent with the proposed localization of their binding sites.[ncbi.nlm.nih.gov] RESULTS: The trial was stopped upon predefined interim analysis after 30 patients because of significant efficacy of tested intervention.[ncbi.nlm.nih.gov]

  • Frostbite

    Two who showed improved but abnormal scans after tPA experienced bleeding complications necessitating stopping heparin/Coumadin.[ncbi.nlm.nih.gov] Stop the soaking when the skin becomes its normal color or loses its numbness.[mayoclinic.com] In severe cases, blood flow to the area may stop, and blood vessels, muscles, nerves, tendons, and bones may be permanently damaged.[webmd.com]

  • Acute Massive Pulmonary Embolism

    After a 10-h infusion she went into labor and streptokinase treatment was stopped.[ncbi.nlm.nih.gov] Thrombolytics used were urokinase, tissue-type plasminogen activator (tPA), and Reteplase.[ncbi.nlm.nih.gov] He had stopped taking anticoagulants as directed by his physician without any bleeding complications. Figure 2. Dilated right ventricle with McConnell’s sign.[evtoday.com]

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