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809 Possible Causes for stop, TPA

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  • Tenecteplase

    Decision rules comparing this dose to rt-PA would cause stopping for futility at phase II end, or continuation to phase III.[] Functional outcomes were very similar to those of 13 patients with early IV-tPA recanalization.[] Decision rules were devised to yield a clear recommendation to either stop for futility or to continue into Phase III.[]

  • Alteplase

    In this case report, we describe a 48-year-old male patient with a history of mechanical aortic valve replacement surgery, who stopped taking prescribed warfarin therapy 2[] OBJECTIVE: To review and evaluate the evidence regarding the use of low-dose regimens of alteplase (tPA) for the treatment of pulmonary embolism (PE).[] The alteplase infusion was stopped, and following antiallergic therapy, tachycardia and hypotension resolved within 1 hour.[]

  • Meningitis

    Meningitis epidemics occur annually during the dry season (January to May) and stop with the first rains.[] At 4 h, 6 min after onset, intravenous administration of rt-PA (alteplase, 0.6 mg/kg) was started. Her neurological deficits improved rapidly, and her NIHSS score was 1.[] This study was stopped early due to excess adverse effects.[]

  • Reteplase

    BACKGROUND: Acute lower gastrointestinal hemorrhage (LGIB) usually stops spontaneously.[] Because they work on the clotting system, tPAs (such as alteplase , reteplase , and tenecteplase ) are used clinically to treat embolic or thrombotic strokes.[] The safety stopping rule was not activated in any of the tiers. One symptomatic intracerebral hemorrhage was observed in one of the 20 patients (in the 1-unit tier).[]

  • Thrombolytic Therapy

    When bleeding from the access site stops and your vital signs are normal, you may be discharged.[] It differs from alteplase by 6 amino acids Indications Acute myocardial infarction- streptokinase, tPA (Alteplase, Reteplase & Tenecteplase) Acute ischemic stroke - tPA (Alteplase[] You may be asked to stop medications that increase the risk of bleeding and other complications.[]

  • Anistreplase

    Check with your health care professional before stopping or starting any of your medicines. What should I watch for while taking anistreplase?[] (tPA, ongoing) (TEAM-III).[] Drug Category Thrombolytic Agents Dosage Forms Powder for solution Brands / Synonyms Alteplase; Eminase (Wulfing Pharma GmbH) ; Reteplase; t- PA; t-plasminogen activator;[]

  • Lanoteplase

    Thrombolytics can stop a heart attack that would otherwise be larger or potentially deadly.[] (Lanoteplase/SUN9216)and Recombinant tPA(Alteplase)for Acute Myocardial Infarction 著者 Ogata Nobuhiko 著者 Ogawa Hisao 著者 Ogata Yasuhiro 著者 Numata Yuichi 著者 Morigami Yasuhiro[] Thrombolytic therapy with mutant tPA or rtPA was carried out consecutively in 21 patients with AMI (8 patients as the mutant tPA group, and 13 patients as the rtPA group).[]

  • Fibrinolysis

    Treatment with rt-PA was stopped, and the patient needed a permanent shunt.[] Both aptamers bind tPA with low nanomolar affinity and inhibit tPA-mediated activities in a way that is consistent with the proposed localization of their binding sites.[] RESULTS: The trial was stopped upon predefined interim analysis after 30 patients because of significant efficacy of tested intervention.[]

  • Frostbite

    Two who showed improved but abnormal scans after tPA experienced bleeding complications necessitating stopping heparin/Coumadin.[] Stop the soaking when the skin becomes its normal color or loses its numbness.[] In severe cases, blood flow to the area may stop, and blood vessels, muscles, nerves, tendons, and bones may be permanently damaged.[]

  • Acute Massive Pulmonary Embolism

    After a 10-h infusion she went into labor and streptokinase treatment was stopped.[] Thrombolytics used were urokinase, tissue-type plasminogen activator (tPA), and Reteplase.[] He had stopped taking anticoagulants as directed by his physician without any bleeding complications. Figure 2. Dilated right ventricle with McConnell’s sign.[]

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