Possible Causes for subependymal nodules Tuberous Sclerosis […] bilateral, predominantly subcortical distribution of subependymal nodules in prior studies of pediatric samples. [ncbi.nlm.nih.gov] Abstract Tuberous sclerosis complex is associated with radiologically visible abnormalities of brain structure, principally tubers and subependymal nodules. [doi.org] nodules, and subependymal giant cell astrocytomas. [emedicine.com] Subependymal Giant Cell Astrocytoma The surgical indications for this lesion and the role of CT in following up subependymal nodules of tuberous sclerosis are discussed. [ncbi.nlm.nih.gov] INTRODUCTION: Subependymal nodule (SEN) and subependymal giant cell astrocytoma (SEGA) are brain lesions frequently found in tuberous sclerosis (TS). [ncbi.nlm.nih.gov] At an early stage, subependymal nodules had different characteristics in patients who developed subependymal giant cell astrocytomas from those who did not. [ncbi.nlm.nih.gov] Fibrillary Astrocytoma Subependymal and parenchymal nodules occur in the cerebrum. [ncbi.nlm.nih.gov] Although giant cell astrocytoma may develop from these subependymal nodules, tumor formation is very rare in the cortical nodules. [ncbi.nlm.nih.gov] Hamartoma of the Central Nervous System Subependymal nodule. Angiomyolipma of the kidney. [pedclerk.bsd.uchicago.edu] Subependymal nodule Tuberous sclerosis. Subependymal nodule. Similar histology to SEGA with frequent calcification. Image provided by Dr Maie Herrick. [neuropathology-web.org] Our patient complied four major clinical features cortical dysplasia, subependymal nodules, cardiac rhabdomyoma, and multiple retinal hamartomas as well as two minor clinical [egms.de] Angiomyolipoma Multiple calcified subependymal nodules (white arrows) in plain CT brain. B. Multiple hyperintense cortical tubers (white arrows) onT2WI MRI. C. [oatext.com] There were no changes in the size of the subependymal nodules. [ojrd.biomedcentral.com] Neurological involvement include subependymal nodules, subependymal giant cell astrocytomas and cortical tubers. [clinicaltrials.gov] Infantile Choroidocerebral Calcification Syndrome The ensuing anomalies of neuronal proliferation and differentiation result in varied expression of hamartomas in the brain—referred to as subependymal nodules and cortical [appliedradiology.com] Usually enhance (cf occasionally mild in subependymal nodule). ?Arise from subependymal nodules. Don’t usually have malignant transformation. [radnotes.co.nz] nodules (Case 286) Bilateral arachnoid cysts, left-sided polymicrogyria (Case 103) Brain metastases in ovarian cancer (Case 142) Breast cancer metastasis to the brain (Case [urmc.rochester.edu] Rhabdomyoma of the Myocardium […] ectopic beats Psychomotor delay Subependymal nodule RV overload signs Subependymal giant cell astrocytoma Multiple rhabdomyomas 21 WPW Syndrome Partial seizures Cortical [bmccardiovascdisord.biomedcentral.com] To further evaluate, noncontrast CT cranium was also done that showed the presence of multiple calcified periventricular subependymal nodules with basal ganglia calcification [mjdrdypu.org] Imaging may reveal the presence of cortical or subependymal tubers. Renal angiomyolipomas usually manifest later in life. [emedicine.medscape.com] Fibroma Symptoms of the sporadic patient with the 3671del8 mutation are cortical tubers, subependymal nodules, facial angiofibroma, ungual fibroma, renal angiomyolipoma, hypomelanotic [wikigenes.org] Renal Fibroma Subependymal nodule (SEN). Subependymal giant cell astrocytoma (SEGA). Cardiac rhabdomyoma, single or multiple. Lymphangiomyomatosis and/or renal angiomyolipoma. [patient.info] nodule Retinal achromatic patch SGCT(subependymal giant cell tumour) Confetti skin lesions Cardiac rhabdomyomas, single or multiple Multiple renal cysts Lymphangiomyomatosis [academic.oup.com] Presence of subependymal nodules and giant cell astrocytoma are sine qua non of TS. Small RCCs can be hyperechoic and indistinguishable from an AML on sonography. [es.slideshare.net] Medial Sclerosis Heterotopia Heterotopia: subependymal nodules (arrows). [radiologyassistant.nl] Subependymal giant cell astrocytoma (SEGA) This is a tumor that develops from a subependymal nodule near the foramen of Monro. [radiologyassistant.nl] There are multiple cortcal and subependymal nodules. The CT shows that most of the lesions are calcified. [radiologyassistant.nl] Platelet-Type Bleeding Disorder 19 nodules of gray matter. [nature.com] Introduction X-linked dominant bilateral periventricular nodular heterotopia (BPNH; MIM #300049) is a neuronal migration disorder characterized by subependymal nodules of [nature.com] […] p.V528M was initially detected in a female autopsy case of X-linked bilateral periventricular nodular heterotopia (BPNH), a neuronal migration disorder characterized by subependymal [nature.com] Status Epilepticus Computed tomography brain scanning revealed bilateral cortex edema and calcified subependymal nodules. [ncbi.nlm.nih.gov] Initial magnetic resonance imaging of the brain revealed diffuse edema in the bilateral cerebral cortex, cortical tubers, and subependymal nodules. [ncbi.nlm.nih.gov] Familial Papillary Thyroid Carcinoma with Papillary Renal Cell Carcinoma […] of the left eye, depigmented skin patches, and magnetic resonance imaging findings of the head characteristic of tsc (subependymal nodules and cortical tubers). [current-oncology.com] At the age of 6, he had been diagnosed with tsc because of the appearance of facial angiofibromas (Pringle nodules, Figure 2), hepatic and renal angiomyolipomas, a hamartoma [current-oncology.com] Temporal Lobe Epilepsy Heterotopia Heterotopia: subependymal nodules (arrows). [radiologyassistant.nl] Subependymal giant cell astrocytoma (SEGA) This is a tumor that develops from a subependymal nodule near the foramen of Monro. [radiologyassistant.nl] There are multiple cortcal and subependymal nodules. The CT shows that most of the lesions are calcified. [radiologyassistant.nl] Familial Cutaneous Collagenoma Subependymal giant cell tumors (also referred to as subependymal giant cell astrocytomas or SEGAs) are thought to develop from subependymal nodules and occur in approximately [clinicaladvisor.com] Subependymal nodules are a major clinical feature that can be quite useful in the diagnosis of TSC. [clinicaladvisor.com] Characteristic findings in individuals with TSC include: – Subependymal nodules, cortical tubers, and/or subependymal giant cell tumor, with or without hydrocephalus in the [clinicaladvisor.com] Pilomyxoid Astrocytoma nodule and subependymal giant cell astrocytoma appears to be radiographic size, with the cut-off being 1 cm (subependymal nodule, smaller; subependymal giant cell astrocytoma [emedicine.medscape.com] These children are at risk of developing subependymal giant cell astrocytomas, cortical tubers, and subependymal nodules. [northshore.org] […] and constitute one of the diagnostic criteria of tuberous sclerosis. [88] Indeed, subependymal giant cell astrocytoma is distinguishable from subependymal nodules only by [emedicine.medscape.com] Cerebral Neoplasm Subependymal nodule Tuberous sclerosis. Subependymal nodule. Similar histology to SEGA with frequent calcification. Image provided by Dr Maie Herrick. [neuropathology-web.org] Major features are cortical tubers, subependymal nodules, subependymal giant cell astrocytomas (SEGA), hypomelanotic skin macules, shagreen patches, retinal nodular hamartomas [neuropathology-web.org] Subependymal giant cell astrocytoma at the foramen of Monro and cortical lesions. SEGA Tuberous sclerosis. Subependymal giant cell astrocytoma. [neuropathology-web.org] Pleomorphic Xanthoastrocytoma nodules (90-100%) and white matter hamartomas and heterotopias (90-100%). [ruralneuropractice.com] Heterotopia Heterotopia: subependymal nodules (arrows). [radiologyassistant.nl] From the imaging findings, differential diagnoses in this case at this point were subependymal giant cell astrocytoma and pilocytic astrocytoma. [ruralneuropractice.com] Generalized Epilepsy with Febrile Seizures Plus Brain pathology consists of calcified subependymal nodules, giant cell astrocytomas, and other areas of focal cortical dysgenesis. [pcs.hmc.washington.edu] Cerebellar Neoplasm Subependymal nodule Tuberous sclerosis. Subependymal nodule. Similar histology to SEGA with frequent calcification. Image provided by Dr Maie Herrick. [neuropathology-web.org] Major features are cortical tubers, subependymal nodules, subependymal giant cell astrocytomas (SEGA), hypomelanotic skin macules, shagreen patches, retinal nodular hamartomas [neuropathology-web.org] Subependymal giant cell astrocytoma at the foramen of Monro and cortical lesions. SEGA Tuberous sclerosis. Subependymal giant cell astrocytoma. [neuropathology-web.org] Parietal Lobe Tumor Heterotopia Heterotopia: subependymal nodules (arrows). [radiologyassistant.nl] Subependymal giant cell astrocytoma (SEGA) This is a tumor that develops from a subependymal nodule near the foramen of Monro. [radiologyassistant.nl] There are multiple cortcal and subependymal nodules. The CT shows that most of the lesions are calcified. [radiologyassistant.nl] Tuberous Sclerosis Type 2 Subependymal nodules can become subependymal giant cell astrocytomas. [columbianeurosurgery.org] nodules, SEGA. [orpha.net] nodule - Subependymal giant cell astrocytoma - Cardiac rhabdomyoma, single or multiple - Renal angiomyolipoma or pulmonary lymphangiomyomatosisb Minor features - Multiple [health.cdc.go.kr] Tuberous Sclerosis Type 1 nodules, SEGA. [orpha.net] nodule - Subependymal giant cell astrocytoma - Cardiac rhabdomyoma, single or multiple - Renal angiomyolipoma or pulmonary lymphangiomyomatosisb Minor features - Multiple [health.cdc.go.kr] "Standardized whole brain mapping of tubers and subependymal nodules in tuberous sclerosis complex". [en.wikipedia.org] Epilepsy It is accompanied by the characteristic brain lesions of cerebral cortical tubers and subependymal nodules, and by the neurological sequelae of epilepsy, variable intellectual [dx.doi.org] Astrocytoma Only one patient developed the tumour suddenly from pre-existing subependymal nodules from the childhood and they had to be removed at 24 years of age. [mendeley.com] By contrast, 32 patients with TSC and images of subependymal nodules whose CT or MR progress was followed up for between 10 and 30 years did not develop a tumour. [mendeley.com] Intestinal Lymphangiectasia Brain magnetic resonance imaging demonstrated a moderate tuber load throughout multiple cerebral lobes and scattered subependymal nodules, consistent with TSC (see Fig. 1) [journals.lww.com] Focal-Onset Impaired-Awareness Seizure Heterotopia Heterotopia: subependymal nodules (arrows). [radiologyassistant.nl] Subependymal giant cell astrocytoma (SEGA) This is a tumor that develops from a subependymal nodule near the foramen of Monro. [radiologyassistant.nl] There are multiple cortcal and subependymal nodules. The CT shows that most of the lesions are calcified. [radiologyassistant.nl] Incessant Infant Ventricular Tachycardia After birth, he was diagnosed as having TSC based on the diagnostic criteria of white leaf-shaped hypomelanotic macules, a subependymal nodule, and a retinal hamartoma [ 4 [bmcpediatr.biomedcentral.com] Lymphangioleiomyomatosis Brain imaging was suggestive of cortical tubers and subependymal nodules. The echocardiography showed right atrial rhabdomyoma. [ncbi.nlm.nih.gov] Baseline cranial MRI scans in patients with tuberous sclerosis showed cortical tubers and subependymal nodules, but no subependymal giant cell astrocytomas and no changes [clincancerres.aacrjournals.org] Neurologic Assessment All patients with the tuberous sclerosis complex had cortical tubers; 64% had subependymal nodules. [doi.org] Neoplasm of the Pancreas They are predisposed to develop three different brain lesions- "tubers," subependymal giant cell astrocytomas and subependymal nodules. [web.archive.org]
