Subepidermal Blistering: Causes & Reasons

Possible Causes for Subepidermal Blistering

blister with variable inflammation Superficial dermis is fibrotic (Type IV collagen positive) Microscopic (histologic) images Images hosted on other servers: EB simplex: [pathologyoutlines.com]

[…] acquisita (EBA) is a chronic autoimmune subepidermal blistering disease of the skin and mucous membranes, causing blisters, scars and milia, mainly in the areas of skin prone [patient.info]

This subepidermal blistering disease occurs in patients that have been diagnosed with systemic lupus erythematosus (SLE), with a low occurrence of only 1%. [physio-pedia.com]

Bullous Pemphigoid

Angel Fernandez-Flores Images hosted on other servers: Eosinophilic infiltrate Subepidermal bullae Subepidermal blister and dermal inflammation Subepidermal blister, numerous [pathologyoutlines.com]

Abstract Bullous pemphigoid (BP) and herpes gestationis (HG) are skin diseases characterized by subepidermal blisters and autoantibodies against two hemidesmosomal Ag, i.e [ncbi.nlm.nih.gov]

Abstract Bullous pemphigoid (BP) is an autoimmune subepidermal blistering disease associated with autoantibodies directed against the hemidesmosomal proteins BP180 and BP230 [ncbi.nlm.nih.gov]

Mucous Membrane Pemphigoid

Mucous membrane pemphigoid (MMP) is a chronic, recurrent, progressive, subepidermal blistering disorder, mainly affecting the mucous membranes. [ncbi.nlm.nih.gov]

Mucous membrane pemphigoid is a rare, chronic autoimmune disease characterized by subepidermal blistering and scarring, predominantly affecting mucous membranes. [ncbi.nlm.nih.gov]

blisters in their skin. [ncbi.nlm.nih.gov]

Acquired Epidermolysis Bullosa

Epidermolysis Bullosa Acquisita definition Form of epidermolysis bullosa characterized by trauma-induced, subepidermal blistering with no family history of the disease. [dermis.net]

INTRODUCTION: Epidermolysis bullosa acquisita (EBA) is an autoimmune subepidermal blistering disease caused by autoantibodies to type VII collagen. [ncbi.nlm.nih.gov]

From Wikidata Jump to navigation Jump to search chronic subepidermal blistering disease associated with autoimmunity to type VII collagen acquired epidermolysis bullosa acquired [wikidata.org]

Herpes Gestationis

Giudice The Journal of clinical investigation 1993 Subepidermal blistering associated with the human skin diseases bullous pemphigoid and herpes gestationis has been thought [semanticscholar.org]

Abstract Bullous pemphigoid (BP) and herpes gestationis (HG) are skin diseases characterized by subepidermal blisters and autoantibodies against two hemidesmosomal Ag, i.e [ncbi.nlm.nih.gov]

Abstract Pemphigoid gestationis (PG) or herpes gestationis is a rare autoimmune subepidermal blistering disorder associated with pregnancy. [ncbi.nlm.nih.gov]

Dermatitis Herpetiformis

Dear Editor, Dermatitis herpetiformis (DH) is a chronic, polymorphic, pruritic autoimmune blistering skin disease characterized by subepidermal blisters, neutrophilic microabscesses [ncbi.nlm.nih.gov]

The resultant injury and inflammation produce a subepidermal blister. [doctoralerts.com]

Dermatitis herpetiformis and bullous pemphigoid are bullous autoimmune diseases of the skin microscopically characterized by subepidermal blisters. [ncbi.nlm.nih.gov]

Epidermolysis Bullosa Pruriginosa

A biopsy specimen showed subepidermal blistering with prominent inflammatory cells, including numerous eosinophils. [wwww.unboundmedicine.com]

Dermatopathology textbooks include hereditary forms of EB among the �cell-poor� list of subepidermal blistering disorders. [dialnet.unirioja.es]

Dermatopathology textbooks include hereditary forms of EB among the "cell-poor" list of subepidermal blistering disorders. [wwww.unboundmedicine.com]

Pretibial Dystrophic Epidermolysis Bullosa

Epidermolysis Bullosa Acquisita Form of epidermolysis bullosa characterized by trauma-induced, subepidermal blistering with no family history of the disease. [bioportfolio.com]

Immunostaining with an antibody LH7:2 against the NC1 domain of collagen VII was positive at the roof and the bottom of the subepidermal blisters. [dokumen.tips]

blister with variable inflammation Superficial dermis is fibrotic (Type IV collagen positive) Microscopic (histologic) images Images hosted on other servers: EB simplex: [pathologyoutlines.com]

Transient Bullous Dermolysis of the Newborn

BACKGROUND: Bullous dermolysis of the newborn (BDN), an extremely rare clinical type of dystrophic epidermolysis bullosa (DEB), is characterized by subepidermal blistering [ncbi.nlm.nih.gov]

TBDN is characterized by subepidermal blisters, reduced or abnormal anchoring fibrils at the dermo-epidermal junction, and electron-dense inclusions in keratinocytes. [ncbi.nlm.nih.gov]

TBDN is characterized by subepidermal blisters, reduced or abnormal an... [eurekamag.com]

Linear IgA Dermatosis

Linear IgA dermatosis is an autoantibody-mediated, subepidermal blistering disease that is rarely associated with drug exposure. [ncbi.nlm.nih.gov]

However, it is not yet certain that this disease constitutes an entity distinct from other subepidermal blistering diseases, especially when IgG deposits are also present. [ncbi.nlm.nih.gov]

Linear IgA dermatosis is a rare autoimmune bullous skin disease with subepidermal blister formation and linear IgA deposits along the basement membrane zone. [ncbi.nlm.nih.gov]

Bullous Lichen Planus

Histologic Features A hyperkeratotic cornified layer Hypergranulosis Irregular epidermal hyperplasia Vacuolar alterations of the basal layer A subepidermal blister with a [dxpath.com]

blister Papillary dermal edema Perivascular lymphocytic infiltrate, sometimes with eosinophils Immunofluorescence shows liner IgG and C3 along the dermal-epidermal junction [dermpedia.org]

Practice Points Lichen planus pemphigoides (LPP) is a rare autoimmune subepidermal blistering disease with few cases reported in the literature. [mdedge.com]

Anti-p200 Pemphigoid

TY - JOUR T1 - Anti-p200 pemphigoid: a novel autoimmune subepidermal blistering disease. [unboundmedicine.com]

Subepidermal blistering disease with autoantibodies against a novel dermal 200- $\kappa$ Da antigen. J Dermatol Sci 2000;23:93-102 5. [koreascience.or.kr]

Abstract Anti-p200 pemphigoid is a recently defined autoimmune subepidermal blistering disease characterized by circulating and tissue-bound autoantibodies to a 200-kDa protein [ncbi.nlm.nih.gov]

Epidermolysis Bullosa Simplex Type Cockayne-Touraine

The mechanisms involved in the development of a subepidermal blister are variable. [basicmedicalkey.com]

In 1969, Eisen postulated that excessive fibroblast collagenase activity was the underlying cause of subepidermal blister formation and dermal collagenolysis in patients with [blog.ebinfoworld.com]

Histopathology revealed a subepidermal blister with minimal inflammatory infiltrate and dermal edema [Figure 4]. [ijpd.in]

Bullous Myringitis

Bullous pemphigoid is a chronic, inflammatory, subepidermal, blistering disease. If untreated, it can persist for months or years, with periods of. [decisionsexpert.ga]

Linear IgA Bullous Dermatosis Autoimmune disease characterized by subepidermal blisters and linear deposition of autoantibodies at the dermoepidermal junction. [ncbi.nlm.nih.gov]

In bullous pemphigoid, the most common subepidermal blistering autoimmune disease, antibodies are directed against the hemidesmosomal antigens BP180 (collagen type XVII) and [glosbe.com]

Hydroa Vacciniforme-Like Lymphoma

No clear subepidermal blister was found. [ncbi.nlm.nih.gov]

Epidermolysis Bullosa

Skin fragility, subepidermal blisters, residual scarring, and milia formation. [accessmedicine.mhmedical.com]

CONSUMERS: Click here for the Consumer Version Epidermolysis bullosa acquisita is a rare, acquired, chronic condition characterized by subepidermal blistering. [msdmanuals.com]

[…] significant morbidity but death due to disease is rare Treatment Corticosteroids and immunosuppressants, but relatively resistant to treatment Microscopic (histologic) description Subepidermal [pathologyoutlines.com]

Dystrophic Epidermolysis Bullosa

Skin biopsy from the shin showed a subepidermal blister with milium. [ncbi.nlm.nih.gov]

Histopathologic exam reveals a subepidermal blister. [dermnet.com]

H&E staining of a biopsy specimen from a dorsal lesion of her right foot showed subepidermal blisters and some inflammatory infiltrates in the upper dermis ( Fig. [medicaljournals.se]

Pemphigus Erythematosus

Histologically, there is a superficial inflammatory cell infiltrate and a subepidermal blister without necrotic keratinocytes. [pemphigus.org]

The blisters are subepidermal and surrounded by a mixed inflammatory cell infiltrate. [aafp.org]

Pemphigoid Pemphigoid is a group of subepidermal, blistering autoimmune diseases that primarily affect the skin, especially the lower abdomen, groin, and flexor surfaces of [pemphigus.org]

Porphyria Cutanea Tarda

Histology revealed an interface dermatitis with focal hyperkeratosis and subepidermal blistering. [ncbi.nlm.nih.gov]

A punch biopsy revealed subepidermal blistering with festooning of dermal papillae associated with a mixed inflammatory infiltrate. [ncbi.nlm.nih.gov]

Histopathology showed a partly regenerated subepidermal blister with a heavy inflammatory cell infiltrate between the old roof and the regenerating base (fig. 2a). [karger.com]

Junctional Epidermolysis Bullosa

blister in a neonate, review the literature regarding cases of epidermolysis bullosa (EB) presenting with inflammatory infiltrates, and discuss mechanisms to explain these [ncbi.nlm.nih.gov]

blistering. [ncbi.nlm.nih.gov]

blister with variable inflammation Superficial dermis is fibrotic (Type IV collagen positive) Microscopic (histologic) images Images hosted on other servers: EB simplex: [pathologyoutlines.com]

Pemphigus

Abstract Cicatricial pemphigoid (CP) is a chronic, autoimmune, subepidermal blistering disease with predominant mucosal involvement. [ncbi.nlm.nih.gov]

Linear IgA bullous dermatosis (LABD) is a rare subepidermal blistering disease with linear IgA deposits at the epidermal basement membrane zone (BMZ). [ncbi.nlm.nih.gov]

On the other hand, subepidermal blister formation in bullous pemphigoid has been believed to be complement-dependent. [ncbi.nlm.nih.gov]

Brunsting-Perry Cicatricial Pemphigoid

Abstract Brunsting-Perry type pemphigoid (BPP) is a rare subepidermal blistering disease and a cause of secondary cicatricial alopecia. [ncbi.nlm.nih.gov]

A lesional skin biopsy showed a subepidermal blister. [ncbi.nlm.nih.gov]

Subepidermal blistering disease with autoantibodies against a novel dermal 200-kDa antigen. J Dermatol Sci. 2000;23(2):93-102. [malattierare.regione.veneto.it]

Bullous Systemic Lupus Erythematosus

Bullous systemic lupus erythematosus is a subepidermal blistering disease that occurs only rarely in a subset of patients with systemic lupus erythematosus and even less commonly [jhu.pure.elsevier.com]

Histopathologic examination showed subepidermal blistering and immunoglobulins (IgG, IgM, IgA) and complement components (C1q, C3) deposited linearly at the basement membrane [ncbi.nlm.nih.gov]

Bullous systemic lupus erythematosus is a subepidermal blistering disorder that primarily affects young women and only rarely occurs in children. [ncbi.nlm.nih.gov]

Multiple Eruptive Milia

blistering skin disease, topical steroid (clobetasol propionate), or a systemic medication (cyclosporine).[2] Primary milia are very common and may affect up to 50% of neonates [njcponline.com]

Secondary milia may occur anywhere following trauma, for example burns, subepidermal blistering diseases, dermabrasion, radiotherapy, or following topical therapy with glucocorticoids [ncbi.nlm.nih.gov]

[…] eccrine sweat ducts[1] and are classified as primary when they arise spontaneously or secondary when they result from skin trauma such as burns, dermabrasion and radiotherapy, subepidermal [njcponline.com]

Pseudoporphyria

Biopsy sample showed subepidermal blister, dermal festooning of papillae and thickened vessels; and the level of urinary porphyrin was within the normal range (1). [scielo.org.pe]

Generalized Dominant Dystrophic Epidermolysis bullosa

Acquired epidermolysis bullosa has subepidermal blistering, showing IgG deposition along the dermal epidermal junction. [skincareguide.ca]

blister with variable inflammation Superficial dermis is fibrotic (Type IV collagen positive) Microscopic (histologic) images Images hosted on other servers: EB simplex: [pathologyoutlines.com]

Histopathology revealed a subepidermal blister with minimal inflammatory infiltrate and dermal edema [Figure 4]. [ijpd.in]

Familial Primary Localized Cutaneous Amyloidosis

JJ Wu, YN Su, CH Hsiao, SH Jee, JW Tjiu and JS Chen, Macular amyloidosis presenting in an incontinentia pigmenti–like pattern with subepidermal blister formation, Journal [doi.org]

blister. [2] Macular and papular forms may coexist in the same patient; this is known as biphasic amyloidosis. [ijdvl.com]

Macular amyloidosis presenting in an incontinentia pigmenti-like pattern with subepidermal blister formation. [e-ijd.org]

Pemphigus Vegetans

The subepidermal blister, seen at the right of the photomicrograph “shot” at high magnification, came into being by virtue of loss of a single layer of basal keratocytes. [derm101.com]

The blisters are subepidermal and surrounded by a mixed inflammatory cell infiltrate. [aafp.org]

+ 10.77.8B: Scattered neutrophils in the edematous upper part of the dermis and in the subepidermal blister = Pemphigus vulgaris, fully developed Much of the intraepidermal [derm101.com]

Familial Hydroa Vacciniforme

Intra- and subepidermal blisters; necrotic areas in the epidermis with surrounding chronic inflammatory infiltrate. [altmeyers.org]

Histology resembles erythema multiforme: mononuclear inflammatory cell infiltrate with edema evolving into subepidermal blisters. [dermatologyadvisor.com]

Anonychia with Flexural Pigmentation

blistering disorder in a 16-year-old female: case report Crisostomo MVN, Lacuesta-Gutierrez MPM 2018-08-31 HTML PDF Atypical cutaneous and mucosal lichen planus in a 53-year-old [spmcpapers.com]

[…] research reports CASE REPORTS Harlequin ichthyosis in a 4-year-old male: case report Ng JNC, Jimenez MSL, Lademora-Dinopol CR, Bunagan MJKS, Tangtatco JAA 2018-08-31 HTML PDF Subepidermal [spmcpapers.com]