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68 Possible Causes for Suprabasal Acantholysis

  • Benign Familial Pemphigus

    Histological examination of typical HHD lesions reveals suprabasal acantholysis with a “dilapidated brick wall” appearance (3).[] Biopsy from the lesion showed suprabasal acantholysis with loss of intercellular bridges resulting in a dilapidated brick-wall appearance; characteristic of Hailey – Hailey[] […] skin showed the typical histopathological features of the heterozygous phenotype with suprabasal clefting and acantholysis sparing the adnexae.[]

  • Dyschromatosis Universalis Hereditaria 1

    Our case however, did not show any evidence of suprabasal acantholysis.[] A histopathological variant of DDD is Galli- Galli disease, which is characterised by suprabasal acantholysis.[] Interestingly, few of the cases of DDD described with hypopigmented lesions have shown suprabasal acantholysis (Galli- Galli variant), thus prompting the hypothesis that hypopigmentation[]

  • Dowling-Degos Disease Type 1

    Our case however, did not show any evidence of suprabasal acantholysis.[] acantholysis on histology, respectively.[6] Based on the locations of the hyperpigmented lesions, palmoplantar pitting, hidradenitis suppurativa, and histopathological findings[] A histopathological variant of DDD is Galli- Galli disease, which is characterised by suprabasal acantholysis.[]

  • Dyschromatosis symmetrica hereditaria

    The histopathologic features of reticulate pigment disorders of the skin are comparable, with the exception of the unique hallmark of suprabasal acantholysis, which can be[] […] of the suprabasal epidermis, which was Case Reports in Dermatological Medicine not observed in our case.[] […] and hyperkeratotic erythematous macules and papules, located in the same areas of Dowling-Degos disease, but has a very peculiar histology demonstrating moderate-tosevere acantholysis[]

  • Bullous Erythroderma Ichthyosiformes

    Darier's disease There is epidermal hyperkeratosis with a suprabasal cleft with areas of acantholysis [Figure 3] a.[] Acantholytic Dyskeratosis Acantholytic dyskeratosis is characterized by the presence of suprabasal acantholysis along with acantholytic and dyskeratotic cells.[] acantholysis with spongiosis.[]

  • Epidermolysis Bullosa Acquisita

    Acantholysis and suprabasal clefts may extend into the follicular units.[] Histopathologically, the epidermis of lesional skin shows widespread suprabasal acantholysis leading to intraepidermal vesicles and bullae, while the epidermis shows the appearance[] The suprabasal bulla contains acantholytic keratinocytes. In the superficial dermis, a sparse perivascular infiltrate of mixed inflammatory cells is present.[]

  • Squamous Cell Carcinoma - Skin or Mucosa

    Skin biopsy was also performed on the abdominal skin lesion and the histology showed suprabasal acantholysis with bullous cleft formation ( Fig. 2B ) and C3 deposits in the[]

  • Disseminated Cytomegalovirus Infection

    A skin biopsy from these lesions showed focal suprabasal acantholysis, epidermal ulceration, upper dermal necrosis, and perivascular infiltration of lymphocytes with nuclear[]

  • Duodenal Ulcer

    The histological findings of her skin were characterized by suprabasal acantholysis and mixed inflammatory cell infiltrates, including scattered eosinophils.[]

  • Pemphigus Foliaceus

    Histological examination of a vesicle disclosed suprabasal acantholysis in contrast to the subcorneal acantholysis discovered upon initial histological evaluation.[] Acantholysis in pemphigus vulgaris (PV) and pemphigus foliaceus (PF) occurs predominantly in the suprabasal area and the granular layer, respectively.[] acantholysis with cleft and vesicle formation Vacuolar interface with spongiosis, dyskeratotic keratinocytes and lymphocyte excocytosis Perivascular lichenoid chronic inflammatory[]

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