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68 Possible Causes for Suprabasal Acantholysis

  • Benign Familial Pemphigus

    Histological examination of typical HHD lesions reveals suprabasal acantholysis with a “dilapidated brick wall” appearance (3).[medicaljournals.se] Biopsy from the lesion showed suprabasal acantholysis with loss of intercellular bridges resulting in a dilapidated brick-wall appearance; characteristic of Hailey – Hailey[odermatol.com] […] skin showed the typical histopathological features of the heterozygous phenotype with suprabasal clefting and acantholysis sparing the adnexae.[thedoctorsdoctor.com]

  • Dyschromatosis Universalis Hereditaria 1

    Our case however, did not show any evidence of suprabasal acantholysis.[omicsonline.org] A histopathological variant of DDD is Galli- Galli disease, which is characterised by suprabasal acantholysis.[omicsonline.org] Interestingly, few of the cases of DDD described with hypopigmented lesions have shown suprabasal acantholysis (Galli- Galli variant), thus prompting the hypothesis that hypopigmentation[omicsonline.org]

  • Dowling-Degos Disease Type 1

    Our case however, did not show any evidence of suprabasal acantholysis.[omicsonline.org] acantholysis on histology, respectively.[6] Based on the locations of the hyperpigmented lesions, palmoplantar pitting, hidradenitis suppurativa, and histopathological findings[jcadonline.com] A histopathological variant of DDD is Galli- Galli disease, which is characterised by suprabasal acantholysis.[omicsonline.org]

  • Dyschromatosis symmetrica hereditaria

    The histopathologic features of reticulate pigment disorders of the skin are comparable, with the exception of the unique hallmark of suprabasal acantholysis, which can be[scienceopen.com] […] of the suprabasal epidermis, which was Case Reports in Dermatological Medicine not observed in our case.[docksci.com] […] and hyperkeratotic erythematous macules and papules, located in the same areas of Dowling-Degos disease, but has a very peculiar histology demonstrating moderate-tosevere acantholysis[docksci.com]

  • Bullous Erythroderma Ichthyosiformes

    Darier's disease There is epidermal hyperkeratosis with a suprabasal cleft with areas of acantholysis [Figure 3] a.[ijdpdd.com] Acantholytic Dyskeratosis Acantholytic dyskeratosis is characterized by the presence of suprabasal acantholysis along with acantholytic and dyskeratotic cells.[ijdpdd.com] acantholysis with spongiosis.[ijdpdd.com]

  • Epidermolysis Bullosa Acquisita

    Acantholysis and suprabasal clefts may extend into the follicular units.[plasticsurgerykey.com] Histopathologically, the epidermis of lesional skin shows widespread suprabasal acantholysis leading to intraepidermal vesicles and bullae, while the epidermis shows the appearance[plasticsurgerykey.com] The suprabasal bulla contains acantholytic keratinocytes. In the superficial dermis, a sparse perivascular infiltrate of mixed inflammatory cells is present.[plasticsurgerykey.com]

  • Squamous Cell Carcinoma - Skin or Mucosa

    Skin biopsy was also performed on the abdominal skin lesion and the histology showed suprabasal acantholysis with bullous cleft formation ( Fig. 2B ) and C3 deposits in the[e-crt.org]

  • Disseminated Cytomegalovirus Infection

    A skin biopsy from these lesions showed focal suprabasal acantholysis, epidermal ulceration, upper dermal necrosis, and perivascular infiltration of lymphocytes with nuclear[medicaljournals.se]

  • Duodenal Ulcer

    The histological findings of her skin were characterized by suprabasal acantholysis and mixed inflammatory cell infiltrates, including scattered eosinophils.[ncbi.nlm.nih.gov]

  • Pemphigus Foliaceus

    Histological examination of a vesicle disclosed suprabasal acantholysis in contrast to the subcorneal acantholysis discovered upon initial histological evaluation.[ncbi.nlm.nih.gov] Acantholysis in pemphigus vulgaris (PV) and pemphigus foliaceus (PF) occurs predominantly in the suprabasal area and the granular layer, respectively.[ncbi.nlm.nih.gov] acantholysis with cleft and vesicle formation Vacuolar interface with spongiosis, dyskeratotic keratinocytes and lymphocyte excocytosis Perivascular lichenoid chronic inflammatory[pathologyoutlines.com]

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