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17 Possible Causes for Susceptibility to Hematologic Malignancies Increased

  • Oral Candidiasis

    . • The patients who are on immunosuppressive drug regimens or who have HIV infection, cancer, or hematologic malignancies have an increased susceptibility to oral candidiasis[]

  • Autosomal Dominant Thrombocytopenia 5

    Affected individuals have an increased susceptibility to the development of hematologic malignancies, and possibly to solid neoplasms.[] THC5 is an autosomal dominant disorder, associated with an increased susceptibility to the development of hematologic and solid malignancies.[] […] petechiae UniProtKB/Swiss-Prot : 75 Thrombocytopenia 5: Thrombocytopenia is defined by a decrease in the number of platelets in circulating blood, resulting in the potential for increased[]

  • Medulloblastoma

    Increased susceptibility to certain tumors, including neuroblastoma and some hematological malignancies, is recognized in disorders caused by mutations in genes encoding components[] Increased susceptibility to certain tumors (neuroblastoma), hematological malignancies (acute lymphoblastic leukemia, acute myeloid leukemia) or disorders caused by mutations[]

  • Splenic Subcapsular Hematoma

    However, splenectomy should be avoided if possible, particularly in children, the elderly, and patients with hematologic malignancy, to avoid the resulting permanent susceptibility[] […] to bacterial infections, increasing the risk of overwhelming postsplenectomy sepsis.[]

  • Gaucher Disease

    In addition to the classic manifestations, patients suffer from increased susceptibility to hematologic and nonhematologic malignancies.[]

  • Infective Dermatitis Associated with HTLV-1

    increase the susceptibility to bacterial infections.[] HTLV-2 does not appear to cause lymphoma or other hematological malignancy, but has been associated with neurologic disease in a small number of infected subjects, and may[]

  • Rothmund Thomson Syndrome

    DNA helicase dysfunction results in an increased susceptibility to cancer, particularly osteosarcoma and skin cancer. Myelodysplasia and hematologic malignancy are rare.[]

  • Fungal Meningitis

    The patients most susceptible to invasive fungal infections include those with hematologic malignancies; those receiving hyperalimentation, corticosteroids, or cytotoxic drugs[] This increase is due to the availability of better diagnostic techniques for fungal infections and the ever-increasing population of immunocompromised hosts (1,2).[]

  • Common Variable Immunodeficiency

    […] to infections, autoimmune diseases, hematologic malignancy, or death caused by infection in other family members should increase the provider’s index of suspicion for CVID[] […] malignant diseases. 15 Although the majority of CVID cases occur sporadically, family history is helpful in securing the correct diagnosis. 15 Known immunodeficiency, unusual susceptibility[]

  • Parainfluenza Virus

    malignancy (HM) patients because of their immunocompromised status and susceptibility to lower respiratory tract infections.[] Advances in diagnostic methods, including polymerase chain reaction, have led to increased identification and awareness of these infections.[] […] infections are increasingly recognized as common causes of morbidity and mortality in cancer patients, particularly in hematopoietic cell transplant (HCT) recipients and hematologic[]

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