Sweat Test Abnormal: Causes & Reasons

Possible Causes for Sweat Test Abnormal

Two sweat tests were abnormal with elevated chloride levels at 78 and 88 mmol/L. DNA sequencing revealed a heterozygous mutation 711+1 G>T and an IVS8-T5 allele. [ncbi.nlm.nih.gov]

This abnormality lead to a diagnostic test for cystic fibrosis, named the sweat test. [healthengine.com.au]

These three patients did not have lung disease typical of cystic fibrosis on the basis of sweat testing, spirometry, or base-line nasal potential-difference measurements. [ncbi.nlm.nih.gov]

Fucosidosis

For example, electron microscopic examination of tissue samples from the skin, liver, spleen, heart, lung, kidney, sweat glands, and/or other cells may reveal abnormal “cavities [rarediseases.org]

The diagnosis may be confirmed thorough clinical evaluation, detailed patient history, and a variety of specialized tests. [rarediseases.org]

Ectodermal Dysplasia

Since she complained of hypohidrosis and intolerance to heat and warm weather and her skin was dry and rough, we did not perform iontophoresis test to confirm the abnormality [dx.doi.org]

As shown by the father of female proband 6, the test easily reveals an abnormal distribution of functioning sweat glands in those body sites that also show the clinical evidence [jamanetwork.com]

[…] of sweat gland function. [dx.doi.org]

Addison Disease

Introduction: Addison’s, also known as primary adrenal insufficiency, was first described by Thomas Addison in 1855 as a syndrome of weakness and hyperpigmentation associated with adrenal gland destruction. As a disease entity, Addison’s remains elusive due to its non-specific symptoms and the overall rarity of the[…] [pedclerk.bsd.uchicago.edu]

Mucopolysaccharidosis

Definition: Systemic lysosomal storage disease caused by a deficiency of alpha-L-iduronidase ( IDURONIDASE ) and characterized by progressive physical deterioration with urinary excretion of DERMATAN SULFATE and HEPARAN SULFATE. There are three recognized phenotypes representing a spectrum of clinical severity[…] [hon.ch]

Hypoparathyroidism

[…] noun mass noun Medicine Diminished concentration of parathyroid hormone in the blood, which causes deficiencies of calcium and phosphorus compounds in the blood and results in muscular spasms. ‘Risks of parathyroid surgery include permanent hypoparathyroidism and damage to the recurrent laryngeal nerve.’[…] [en.oxforddictionaries.com]

Myxedema

Ureteral myxedema is exceptionally rare. We describe computed tomography and magnetic resonance imaging findings in a case of ureteral myxedema. The demonstration of water-like hyperintensity around the ureteral lumen on heavily T2-weighted sequences should be considered a strongly suggestive sign for ureteral[…] [ncbi.nlm.nih.gov]

Glycogen Storage Disease

Successfully reported this slideshow. ... Published on Jan 2, 2015 GLYCOGEN STORAGE DISEASES (GSDs) GLYCOGEN STORAGE DISEASES 1.  The metabolic defects concerned with the glycogen synthesis and degradation are collectively referred to as glycogen storage diseases.  These disorders are due to defects in the[…] [slideshare.net]

Glycogen Storage Disease Type 1

Glycogen storage disease type 1 (GSD1) is an inborn error of metabolism caused by deficiency of glucose-6-phosphatase, the enzyme catalysing the conversion of glucose-6-phosphate (G6P) to glucose. GSD1 is associated with severe hyperlipidaemia and hepatic steatosis. The underlying mechanisms responsible for these[…] [ncbi.nlm.nih.gov]

Nephrogenic Diabetes Insipidus

To view the fulltext, please log in To view the pdf, please log in Buy FullText & PDF Unlimited re-access via MyKarger Unrestricted printing, no saving restrictions for personal use read more CHF 38.00 * EUR 35.00 * USD 39.00 * Select KAB Buy a Karger Article Bundle (KAB) and profit from a discount ! If you would[…] [karger.com]

Kwashiorkor

Definitions kwa·shi·or·kor a severe disease of young children, caused by chronic deficiency of protein and calories in the diet and characterized by stunted growth, edema, and a protuberant belly Origin of kwashiorkor from name in a Kwa language of Ghana Webster's New World College Dictionary, Fifth Edition[…] [yourdictionary.com]

Barakat Syndrome

Autoimmune Peripheral Neuropathy

[…] epidermal nerve fiber density (ENFD); abnormal sweat gland nerve fiber density (SGNFD); abnormal sudomotor testing using SUDOSCAN’s measures (the following normative values [impeto-medical.com]

[…] fiber neuropathy was defined as a combination of clinical signs suggestive of small fiber dysfunction and at least one of the following structural or functional variables: abnormal [impeto-medical.com]

Navajo Poikiloderma

Several broncho-pulmonary infectious episodes complicated the evolution, and cystic fibrosis was first considered on the basis of repeated abnormal sweat chloride tests but [hal.archives-ouvertes.fr]

Bronchiectasis with or without Elevated Sweat Chloride 3

It leads to chronic lung disease, exocrine pancreatic insufficiency, hepatobiliary disease, and abnormally high sweat electrolytes. [msdmanuals.com]

Generally such patients have at least one undisputedly abnormal sweat test, two identified CF causing mutations and a phenotype (clinical presentation) compatible with CF [cfmedicine.com]

CONCLUSIONS Cystic fibrosis is a genetic disease usually diagnosed by abnormal sweat testing. [tmg.org.rs]

Acute Pandysautonomia

Abnormal quantitative sudomotor axon reflex test and thermoregulatory sweat test and an excessive orthostatic increase of catecholamines were found in some patients. [mayoclinic.pure.elsevier.com]

A decreased sweat output on the quantitative sudomotor axon reflex test is the most frequent abnormal finding in the POST-AN group suggesting sympathetic cholinergic neuropathy [curezone.org]

Idiopathic Bronchiectasis

Historically, the diagnosis of CF has been based on the presence of typical clinical features and positive laboratory studies, including abnormal sweat tests or two identified [rarediseasesnetwork.org]

Participants whose initial tests show abnormal results may also be asked to have a nasal scrape to collect cell samples and/or a skin sweat test to measure salt concentrations [clinicaltrials.gov]

Chronic Berylliosis

Medical tests may reveal abnormal lung sounds, lung scars, decreased pulmonary function, granulomas (a nodular form of chronic inflammation) and an allergy to beryllium. [web.archive.org]

Its symptoms include coughing, shortness of breath, fatigue, weight loss or loss of appetite, fever and sweating. [web.archive.org]

Holmes-Adie Syndrome

[…] in sweating between test sites (in one of the tests, 43%) which is consistent with patchy loss. [ncbi.nlm.nih.gov]

Sweating was marked in the right axilla. There were no respiratory system abnormalities. Cardiovascular autonomic testing suggested an afferent baroreceptor lesion. [jnnp.bmj.com]

Cardiovascular and sweating abnormality did not concur significantly and only the former was found to increase progressively with known duration of the pupillotonia. [ncbi.nlm.nih.gov]

Cold-Induced Sweating Syndrome Type 1

1 Autonomic Reflex Screen Test Abnormalities in Cold-Induced Sweating Syndrome Type 1. ( 29189552 ) El-Dokla A.M....Alam K. 2017 2 Warmth and Nociceptive Evoked Potentials [malacards.org]

(QSART) abnormalities in genetically confirmed Cold-Induced Sweating Syndrome Type 1 BACKGROUND: Cold-induced sweating syndrome type 1 (CISS1) is a rare autosomal recessive [neurology.org]

Ferdous, Sahawat Tantikittichaikul, Sara Ali, Khondoker Alam, Ahmed Eldokla First published April 8, 2015, Abstract OBJECTIVE: To report Quantitative sudomotor axon reflex test [neurology.org]

Pure Autonomic Failure

Autonomic tests showed low circulating norepinephrine levels, sweating abnormalities with regional anhydrosis of the left side of the trunk and abnormal cardiovagal response [ncbi.nlm.nih.gov]

Quantitative sensory testing showed abnormal thresholds to all thermal modalities. [ncbi.nlm.nih.gov]

The thermoregulatory sweat test provides a quantitative measure of the patient's ability to respond to heat and humidity by sweating. [symptoma.com]

Auriculotemporal Syndrome

The Minor starch-iodine test was performed, revealing areas of abnormal sweating (figure 1). [n.neurology.org]

Two weeks following intradermal injection of botulinum toxin targeting areas of hyperhidrosis, symptoms resolved and repeat Minor test revealed resolution of abnormal sweating [n.neurology.org]

Gustatory sweating is caused by abnormal innervation of facial sweat glands by sprouting parasympathetic fibers following an injury to auriculotemporal nerve.1 The distribution [n.neurology.org]

Orthostatic Intolerance due to NET Deficiency

Other studies label patients with “Neuropathic POTS”if the QSART sweat test is abnormal. [ihpotblogspot.blogspot.com]

Another 5 patients had neurophysiologic evidence of distal small fiber neuropathy, 2 distal anhidrosis (thermoregulatory sweat test), 2 elevated thresholds for cold sensation [doi.org]

Thermoregulatory Sweat Test (TST), skin biopsies looking at the small fiber nerves, gastric motility studies and more. [dysautonomiainternational.org]

Berylliosis

Medical tests may reveal abnormal lung sounds, lung scars, decreased pulmonary function, granulomas (a nodular form of chronic inflammation) and an allergy to beryllium. [web.archive.org]

Its symptoms include coughing, shortness of breath, fatigue, weight loss or loss of appetite, fever and sweating. [web.archive.org]

AMACR Deficiency

In this patient cystic fibrosis was confirmed by an abnormal sweat test, abnormal ion transport in rectal epithelial cells and heterozygosity for the mutation ΔF508 in the [wjgnet.com]

Autonomic Nervous System Disorder

[…] response and distribution of sweat patterns Other symptoms of abnormal autonomic reflexes These tests help determine whether an autonomic disorder is benign or life-threatening [froedtert.com]

Doctors examine the pupils for abnormal responses or lack of response to changes in light. Sweat testing is also done. [merckmanuals.com]

[…] physicians with expertise in autonomic disorders use non-invasive procedures to precisely assess symptoms of autonomic disorders such as: Tachycardia Dizziness Fainting Sweat [froedtert.com]

Dysautonomia

[…] and autonomic testing demonstrating abnormal responses to quantitative sweat testing and cardiovagal function testing. [ncbi.nlm.nih.gov]

Your physician may recommend autonomic testing if you’re experiencing symptoms including: Abnormal sweating Dizziness Fainting Fatigue Fluctuating blood pressure Numbness [scripps.org]

× The thermoregulatory sweat test and the quantitative sudomotor axon reflex test both determine the sweat gland function and the integrity of efferent cholinergic sympathetic [doi.org]

Pancreatic Insufficiency

The patient did not have any evidence of disorders known to be associated with an abnormal sweat test, including most importantly cystic fibrosis. [ncbi.nlm.nih.gov]

This report describes a 15-year-old girl with anorexia nervosa whose sweat electrolytes and pancreatic exocrine function were abnormal during a state of malnutrition. [ncbi.nlm.nih.gov]

Polyglucosan Body Myopathy Type 2

Electrophysiologic testing is nonspecific: Specialized autonomic testing (thermoregulatory sweat tests and autonomic reflex testing) shows sudomotor sweating abnormalities [ncbi.nlm.nih.gov]

Prerenal Azotemia

2 abnormal but non-diagnostic sweat tests, and a common CFTR mutation. [indianjnephrol.org]

Also possible but even less likely is an abnormality of the epithelial sodium channel, which can result in abnormal sweat test values and a CF-like presentation; [2] genetics [indianjnephrol.org]

During his work-up for his ARF, he was found to have a family history of CF, F508del/unknown CFTR genotype, and abnormal sweat tests. [indianjnephrol.org]